{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T03:13:38Z","timestamp":1788232418094,"version":"build-2803163510"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,31]]},"DOI":"10.7759\/cureus.115552","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T02:32:11Z","timestamp":1788229931000},"source":"Crossref","is-referenced-by-count":0,"title":["Male Senescence Phenotypes Include Hair Loss and Hair Gain"],"prefix":"10.7759","author":[{"given":"Colleen","family":"Reisz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An-Lin","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.10.039","article-title":"Geroscience: linking aging to chronic disease","volume":"159","author":"Kennedy BK","year":"2014","unstructured":"Kennedy BK, Berger SL, Brunet A, et al.. Geroscience: linking aging to chronic disease. Cell. 2014, 159:709-13. 10.1016\/j.cell.2014.10.039","journal-title":"Cell"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.11.001","article-title":"Hallmarks of aging: an expanding universe","volume":"186","author":"L\u00f3pez-Ot\u00edn C","year":"2023","unstructured":"L\u00f3pez-Ot\u00edn C, Blasco MA, Partridge L, Serrano M, Kroemer G. Hallmarks of aging: an expanding universe. Cell. 2023, 186:243-78. 10.1016\/j.cell.2022.11.001","journal-title":"Cell"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S275785","article-title":"The inflammatory aspect of male and female pattern hair loss","volume":"13","author":"Peyravian N","year":"2020","unstructured":"Peyravian N, Deo S, Daunert S, Jimenez JJ. The inflammatory aspect of male and female pattern hair loss. J Inflamm Res. 2020, 13:879-81. 10.2147\/JIR.S275785","journal-title":"J Inflamm Res"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2015.220","article-title":"Prediction of male-pattern baldness from genotypes","volume":"24","author":"Liu F","year":"2016","unstructured":"Liu F, Hamer MA, Heilmann S, et al.. Prediction of male-pattern baldness from genotypes. Eur J Hum Genet. 2016, 24:895-902. 10.1038\/ejhg.2015.220","journal-title":"Eur J Hum Genet"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.12.005","article-title":"The hair follicle as a dynamic miniorgan","volume":"19","author":"Schneider MR","year":"2009","unstructured":"Schneider MR, Schmidt-Ullrich R, Paus R. The hair follicle as a dynamic miniorgan. Curr Biol. 2009, 19:R132-42. 10.1016\/j.cub.2008.12.005","journal-title":"Curr Biol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12965","article-title":"Hunting the genes in male-pattern alopecia: how important are they, how close are we and what will they tell us?","volume":"25","author":"Heilmann-Heimbach S","year":"2016","unstructured":"Heilmann-Heimbach S, Hochfeld LM, Paus R, N\u00f6then MM. Hunting the genes in male-pattern alopecia: how important are they, how close are we and what will they tell us?. Exp Dermatol. 2016, 25:251-7. 10.1111\/exd.12965","journal-title":"Exp Dermatol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.720879","article-title":"The roles of non-coding RNA in the development and regeneration of hair follicles: current status and further perspectives","volume":"9","author":"Yang M","year":"2021","unstructured":"Yang M, Weng T, Zhang W, Zhang M, He X, Han C, Wang X. The roles of non-coding RNA in the development and regeneration of hair follicles: current status and further perspectives. Front Cell Dev Biol. 2021, 9:720879. 10.3389\/fcell.2021.720879","journal-title":"Front Cell Dev Biol"},{"key":"ref8","article-title":"Male-pattern hair loss: comprehensive identification of the associated genes as a basis for understanding pathophysiology","volume":"35","author":"Henne SK","year":"2023","unstructured":"Henne SK, N\u00f6then MM, Heilmann-Heimbach S. Male-pattern hair loss: comprehensive identification of the associated genes as a basis for understanding pathophysiology. Med Genet. 2023, 35:3-14.","journal-title":"Med Genet"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.323.7309.369","article-title":"Maternal and paternal age at delivery, birth order, and risk of childhood onset type 1 diabetes: population based cohort study","volume":"323","author":"Stene LC","year":"2001","unstructured":"Stene LC, Magnus P, Lie RT, S\u00f8vik O, Joner G. Maternal and paternal age at delivery, birth order, and risk of childhood onset type 1 diabetes: population based cohort study. BMJ. 2001, 323:369. 10.1136\/bmj.323.7309.369","journal-title":"BMJ"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/437107","article-title":"Developmental programming of nonalcoholic fatty liver disease: the effect of early life nutrition on susceptibility and disease severity in later life","volume":"2015","author":"Li M","year":"2015","unstructured":"Li M, Reynolds CM, Segovia SA, Gray C, Vickers MH. Developmental programming of nonalcoholic fatty liver disease: the effect of early life nutrition on susceptibility and disease severity in later life. Biomed Res Int. 2015, 2015:437107. 10.1155\/2015\/437107","journal-title":"Biomed Res Int"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1237427","article-title":"Developmental origins of health and disease: environmental exposures","volume":"27","author":"Swanson JM","year":"2009","unstructured":"Swanson JM, Entringer S, Buss C, Wadhwa PD. Developmental origins of health and disease: environmental exposures. Semin Reprod Med. 2009, 27:391-402. 10.1055\/s-0029-1237427","journal-title":"Semin Reprod Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.178536","article-title":"Classifications of patterned hair loss: a review","volume":"9","author":"Gupta M","year":"2016","unstructured":"Gupta M, Mysore V. Classifications of patterned hair loss: a review. J Cutan Aesthet Surg. 2016, 9:3-12. 10.4103\/0974-2077.178536","journal-title":"J Cutan Aesthet Surg"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1979.04010080002004","article-title":"Whisker hair","volume":"115","author":"Norwood OT","year":"1979","unstructured":"Norwood OT. Whisker hair. Arch Dermatol. 1979, 115:930-1. 10.1001\/archderm.1979.04010080002004","journal-title":"Arch Dermatol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2017.09.014","article-title":"Organization of sensory feature selectivity in the whisker system","volume":"368","author":"Bale MR","year":"2018","unstructured":"Bale MR, Maravall M. Organization of sensory feature selectivity in the whisker system. Neuroscience. 2018, 368:70-80. 10.1016\/j.neuroscience.2017.09.014","journal-title":"Neuroscience"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00261.2020","article-title":"Thalamic state influences timing precision in the thalamocortical circuit","volume":"125","author":"Whitmire CJ","year":"2021","unstructured":"Whitmire CJ, Liew YJ, Stanley GB. Thalamic state influences timing precision in the thalamocortical circuit. J Neurophysiol. 2021, 125:1833-50. 10.1152\/jn.00261.2020","journal-title":"J Neurophysiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/biology13050312","article-title":"Modelling human hair follicles-lessons from animal models and beyond","volume":"13","author":"Tan CT","year":"2024","unstructured":"Tan CT, Lim CY, Lay K. Modelling human hair follicles-lessons from animal models and beyond. Biology (Basel). 2024, 13:10.3390\/biology13050312","journal-title":"Biology (Basel)"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/exd.14155","article-title":"Hair follicle immune privilege and its collapse in alopecia areata","volume":"29","author":"Bertolini M","year":"2020","unstructured":"Bertolini M, McElwee K, Gilhar A, Bulfone-Paus S, Paus R. Hair follicle immune privilege and its collapse in alopecia areata. Exp Dermatol. 2020, 29:703-25. 10.1111\/exd.14155","journal-title":"Exp Dermatol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.933370","article-title":"Hair follicle morphogenesis during embryogenesis, neogenesis, and organogenesis","volume":"10","author":"Park S","year":"2022","unstructured":"Park S. Hair follicle morphogenesis during embryogenesis, neogenesis, and organogenesis. Front Cell Dev Biol. 2022, 10:933370. 10.3389\/fcell.2022.933370","journal-title":"Front Cell Dev Biol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3390\/cells11030562","article-title":"The origins of NAFLD: the potential implication of intrauterine life and early postnatal period","volume":"11","author":"Valentini F","year":"2022","unstructured":"Valentini F, Rocchi G, Vespasiani-Gentilucci U, Guarino MP, Altomare A, Carotti S. The origins of NAFLD: the potential implication of intrauterine life and early postnatal period. Cells. 2022, 11:10.3390\/cells11030562","journal-title":"Cells"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1989.61.2.311","article-title":"Thalamocortical response transformation in the rat vibrissa\/barrel system","volume":"61","author":"Simons DJ","year":"1989","unstructured":"Simons DJ, Carvell GE. Thalamocortical response transformation in the rat vibrissa\/barrel system. J Neurophysiol. 1989, 61:311-30. 10.1152\/jn.1989.61.2.311","journal-title":"J Neurophysiol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adh3273","article-title":"Mechanical stimulation of human hair follicle outer root sheath cultures activates adjacent sensory neurons","volume":"9","author":"Agramunt J","year":"2023","unstructured":"Agramunt J, Parke B, Mena S, et al.. Mechanical stimulation of human hair follicle outer root sheath cultures activates adjacent sensory neurons. Sci Adv. 2023, 9:eadh3273. 10.1126\/sciadv.adh3273","journal-title":"Sci Adv"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0202969","article-title":"Sensory-specific impairment among older people. An investigation using both sensory thresholds and subjective measures across the five senses","volume":"13","author":"Cavazzana A","year":"2018","unstructured":"Cavazzana A, R\u00f6hrborn A, Garthus-Niegel S, Larsson M, Hummel T, Croy I. Sensory-specific impairment among older people. An investigation using both sensory thresholds and subjective measures across the five senses. PLoS One. 2018, 13:e0202969. 10.1371\/journal.pone.0202969","journal-title":"PLoS One"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/503761-male-senescence-phenotypes-include-hair-loss-and-hair-gain","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T02:32:12Z","timestamp":1788229932000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/503761-male-senescence-phenotypes-include-hair-loss-and-hair-gain"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.115552","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,31]]}}}