{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:59:33Z","timestamp":1787032773986,"version":"build-2736575974"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,20]]},"DOI":"10.7759\/cureus.11583","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T03:22:56Z","timestamp":1605842576000},"source":"Crossref","is-referenced-by-count":16,"title":["Varicella-Zoster Virus Meningitis and Encephalitis: An Understated Cause of Central Nervous System Infections"],"prefix":"10.7759","author":[{"given":"Jose C","family":"Alvarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Ticono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricio","family":"Medallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector","family":"Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Ferr\u00e9s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Forero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-009-9092-5","article-title":"Herpes zoster meningoencephalitis: not only a disease of the immunocompromised?","volume":"38","author":"Douglas A","year":"2010","unstructured":"Douglas A, Harris P, Francis F, Norton R. Herpes zoster meningoencephalitis: not only a disease of the immunocompromised?. Infection. 2010, 38:73-75. 10.1007\/s15010-009-9092-5","journal-title":"Infection"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.17.4.903-925.2004","article-title":"Molecular methods for diagnosis of viral encephalitis","volume":"17","author":"DeBiasi RL","year":"2004","unstructured":"DeBiasi RL, Tyler KL. Molecular methods for diagnosis of viral encephalitis. Clin Microbiol Rev. 2004, 17:903-925. 10.1128\/CMR.17.4.903-925.2004","journal-title":"Clin Microbiol Rev"},{"key":"ref3","doi-asserted-by":"crossref","DOI":"10.5858\/2001-125-0770-VZVIOT","article-title":"Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates","volume":"125","author":"Kleinschmidt-DeMasters BK","year":"2001","unstructured":"Kleinschmidt-DeMasters BK, Gilden DH. Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates. Arch Pathol Lab Med. 2001, 125:770-180.","journal-title":"Arch Pathol Lab Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1086\/648419","article-title":"Infectious encephalitis in France in 2007: a national prospective study","volume":"49","author":"Alexandra Mailles","year":"2009","unstructured":"Alexandra Mailles, Stahl JP. Infectious encephalitis in France in 2007: a national prospective study. Clin Infect Dis. 2009, 49:1838-1847. 10.1086\/648419","journal-title":"Clin Infect Dis"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-007575","article-title":"Herpes zoster as a cause of viral meningitis in immunocompetent patients","volume":"2013","author":"Kangath RV","year":"2013","unstructured":"Kangath RV, Lindeman TE, Brust K. Herpes zoster as a cause of viral meningitis in immunocompetent patients. BMJ Case Rep. 2013, 2013:bcr2012007575. 10.1136\/bcr-2012-007575","journal-title":"BMJ Case Rep"},{"key":"ref6","unstructured":"Orrego C. Convenio de Desempe\u00f1o Colectivo. Gobierno Regional Metropolitano de Santiago. (2017). https.\/\/www.gobiernosantiago.cl\/wp-content\/uploads\/2017\/01\/CDC-2017-1.pdf."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2009.07.014","article-title":"Varicella-zoster virus CNS disease-viral load, clinical manifestations and sequels","volume":"46","author":"Persson A","year":"2009","unstructured":"Persson A, Bergstr\u00f6m T, Lindh M, Namvar L, Studahl M. Varicella-zoster virus CNS disease-viral load, clinical manifestations and sequels. J Clin Virol. 2009, 46:249-253. 10.1016\/j.jcv.2009.07.014","journal-title":"J Clin Virol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2013.01.031","article-title":"Infection of the central nervous system caused by varicella zoster virus reactivation: a retrospective case series study","volume":"17","author":"Lozano Becerra JC","year":"2013","unstructured":"Lozano Becerra JC, Sieber R, Martinetti G, Costa ST, Meylan P, Bernasconi E. Infection of the central nervous system caused by varicella zoster virus reactivation: a retrospective case series study. Int J Infect Dis. 2013, 17:529-534. 10.1016\/j.ijid.2013.01.031","journal-title":"Int J Infect Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03705.x","article-title":"Acute varicella zoster encephalitis without evidence of primary vasculopathy in a case-series of 20 patients","volume":"18","author":"De Broucker T","year":"2012","unstructured":"De Broucker T, Mailles A, Chabrier S, Morand P, Stahl JP. Acute varicella zoster encephalitis without evidence of primary vasculopathy in a case-series of 20 patients. Clin Microbiol Infect. 2012, 18:808-819. 10.1111\/j.1469-0691.2011.03705.x","journal-title":"Clin Microbiol Infect"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1086\/591129","article-title":"Clinical features of viral meningitis in adults: significant differences in cerebrospinal fluid findings among herpes simplex virus, varicella zoster virus, and enterovirus infections","volume":"15","author":"Ihekwaba UK","year":"2008","unstructured":"Ihekwaba UK, Kudesia G, McKendrick MW. Clinical features of viral meningitis in adults: significant differences in cerebrospinal fluid findings among herpes simplex virus, varicella zoster virus, and enterovirus infections. Clin Infect Dis. 2008, 15:783-789. 10.1086\/591129","journal-title":"Clin Infect Dis"},{"key":"ref11","article-title":"Mandell, Douglas, and Bennet\u2019s Principles and Practice of Infectious Diseases. 7th ed","author":"Mandell","year":"2009","unstructured":"Mandell, Bennett JE, Dolin R, et al.. Mandell, Douglas, and Bennet\u2019s Principles and Practice of Infectious Diseases. 7th ed. Churchill Livingstone Elsevier, London, United Kingdom; 2009."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu137","article-title":"Focal encephalitis following varicella-zoster virus reactivation without rash in a healthy immunized young adult","volume":"210","author":"Halling G","year":"2014","unstructured":"Halling G, Giannini C, Britton JW, et al.. Focal encephalitis following varicella-zoster virus reactivation without rash in a healthy immunized young adult. J Infect Dis. 2014, 210:713-716. 10.1093\/infdis\/jiu137","journal-title":"J Infect Dis"},{"key":"ref13","doi-asserted-by":"crossref","DOI":"10.1111\/j.1468-1331.2008.02233.x","article-title":"Aseptic meningitis and encephalitis because of herpesviruses and enteroviruses in an immunocompetent adult population","volume":"15","author":"Frantzidou F","year":"2008","unstructured":"Frantzidou F, Kamaria F, Dumaidi K, Skoura L, Antoniadis A, Papa A. Aseptic meningitis and encephalitis because of herpesviruses and enteroviruses in an immunocompetent adult population. Eur J Neurol. 2008, 15:995-997.","journal-title":"Eur J Neurol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2015.06.004","article-title":"Varicella-zoster virus infections of the central nervous system - prognosis, diagnostics and treatment","volume":"71","author":"Grahn A","year":"2015","unstructured":"Grahn A, Studahl M. Varicella-zoster virus infections of the central nervous system - prognosis, diagnostics and treatment. J Infect. 2015, 71:281-293. 10.1016\/j.jinf.2015.06.004","journal-title":"J Infect"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa185","article-title":"","author":"Herlin","year":"2020","unstructured":"Herlin, Hansen, Bodilsen, et al.. Clinical Infectious Diseases. 2020 Feb 27. 10.1093\/cid\/ciaa185"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research","article-title":"Varicella zoster virus in the nervous system","volume":"4","author":"Gilden D","year":"2015","unstructured":"Gilden D, Nagel M, Cohrs R, Mahalingam R, Baird N. Varicella zoster virus in the nervous system. F1000Res. 2015, 4:1356. 10.12688\/f1000research","journal-title":"F1000Res"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30245-7","article-title":"Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study","volume":"18","author":"McGill F","year":"2018","unstructured":"McGill F, Griffiths MJ, Bonnett LJ, et al.. Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study. Lancet Infect Dis. 2018, 18:992-1003. 10.1016\/S1473-3099(18)30245-7","journal-title":"Lancet Infect Dis"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-017-0993-4","article-title":"A retrospective study of viral central nervous system infections: relationship amongst aetiology, clinical course and outcome","volume":"1","author":"Calleri G","year":"2017","unstructured":"Calleri G, Libanore V, Corcione S, De Rosa FG, Caramello P. A retrospective study of viral central nervous system infections: relationship amongst aetiology, clinical course and outcome. Infection. 2017, 1:227-231. 10.1007\/s15010-017-0993-4","journal-title":"Infection"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.23690","article-title":"Diagnostic value of a \u201cwide-range\u201d quantitative nested real-time PCR assay for varicella zoster virus myelitis","volume":"1","author":"Takahashi T","year":"2013","unstructured":"Takahashi T, Tamura M, Takasu T. Diagnostic value of a \u201cwide-range\u201d quantitative nested real-time PCR assay for varicella zoster virus myelitis. J Med Virol. 2013, 1:2042-2055. 10.1002\/jmv.23690","journal-title":"J Med Virol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/45507-varicella-zoster-virus-meningitis-and-encephalitis-an-understated-cause-of-central-nervous-system-infections","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T14:29:50Z","timestamp":1707488990000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/45507-varicella-zoster-virus-meningitis-and-encephalitis-an-understated-cause-of-central-nervous-system-infections"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,20]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.11583","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11,20]]}}}