{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T08:09:07Z","timestamp":1789027747105,"version":"build-2803163510"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,10]]},"DOI":"10.7759\/cureus.116031","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:39:43Z","timestamp":1789025983000},"source":"Crossref","is-referenced-by-count":0,"title":["Pancytopenia and Hypocalcemia: An Unexpected Cause"],"prefix":"10.7759","author":[{"given":"Gabriela","family":"Paulo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Veiga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Oliveira Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilda","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i40.11428","article-title":"Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge","volume":"21","author":"Pernot S","year":"2015","unstructured":"Pernot S, Voron T, Perkins G, Lagorce-Pages C, Berger A, Taieb J. Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge. World J Gastroenterol. 2015, 21:11428-38. 10.3748\/wjg.v21.i40.11428","journal-title":"World J Gastroenterol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v26.i39.6037","article-title":"Metastatic pattern in esophageal and gastric cancer: Influenced by site and histology","volume":"26","author":"Verstegen MH","year":"2020","unstructured":"Verstegen MH, Harker M, van de Water C, et al.. Metastatic pattern in esophageal and gastric cancer: Influenced by site and histology. World J Gastroenterol. 2020, 26:6037-46. 10.3748\/wjg.v26.i39.6037","journal-title":"World J Gastroenterol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.14744\/ejmo.2017.65365","article-title":"Gastric cancer patients with bone marrow metastasis: A single-center experience and review of the literature","volume":"1","author":"Ergun Y","year":"2017","unstructured":"Ergun Y, Uncu D, Yaz\u0131c\u0131 O, Ucar G, Karabuga EK, Zengin N. Gastric cancer patients with bone marrow metastasis: A single-center experience and review of the literature. Eurasian J Med Oncol. 2017, 1:160-163. 10.14744\/ejmo.2017.65365","journal-title":"Eurasian J Med Oncol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2013.07.001","article-title":"Tumor lysis syndrome: New challenges and recent advances","volume":"21","author":"Wilson FP","year":"2014","unstructured":"Wilson FP, Berns JS. Tumor lysis syndrome: New challenges and recent advances. Adv Chronic Kidney Dis. 2014, 21:18-26. 10.1053\/j.ackd.2013.07.001","journal-title":"Adv Chronic Kidney Dis"},{"key":"ref5","article-title":"Update on diagnosis and treatment of early signet-ring cell gastric carcinoma: A literature review","volume":"15","author":"Tang YH","year":"2023","unstructured":"Tang YH, Ren LL, Mao T. Update on diagnosis and treatment of early signet-ring cell gastric carcinoma: A literature review. World J Gastrointest Endosc. 2023, 15:240-7.","journal-title":"World J Gastrointest Endosc"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0000000000001481","article-title":"18F-FDG PET and PET\/CT for the evaluation of gastric signet ring cell carcinoma: A systematic review","volume":"42","author":"Dondi F","year":"2021","unstructured":"Dondi F, Albano D, Giubbini R, Bertagna F. 18F-FDG PET and PET\/CT for the evaluation of gastric signet ring cell carcinoma: A systematic review. Nucl Med Commun. 2021, 42:1293-300. 10.1097\/MNM.0000000000001481","journal-title":"Nucl Med Commun"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1986.tb02745.x","article-title":"A hospital survey of hypocalcemia in patients with malignant disease","volume":"220","author":"Blomqvist CP","year":"1986","unstructured":"Blomqvist CP. A hospital survey of hypocalcemia in patients with malignant disease. Acta Med Scand. 1986, 220:167-73. 10.1111\/j.0954-6820.1986.tb02745.x","journal-title":"Acta Med Scand"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000029731","article-title":"Severe and refractory hypocalcaemia secondary to osteoblastic bone metastases in bladder signet ring carcinoma: A case report and literature review","volume":"101","author":"Zeng W","year":"2022","unstructured":"Zeng W, Swee DS. Severe and refractory hypocalcaemia secondary to osteoblastic bone metastases in bladder signet ring carcinoma: A case report and literature review. Medicine (Baltimore). 2022, 101:e29731. 10.1097\/MD.0000000000029731","journal-title":"Medicine (Baltimore)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.56.8545","article-title":"Paraneoplastic hypocalcemia developed in gastric cancer accompanied by osteoblastic metastasis","volume":"56","author":"Okazaki J","year":"2017","unstructured":"Okazaki J, Muguruma N, Kitamura S, et al.. Paraneoplastic hypocalcemia developed in gastric cancer accompanied by osteoblastic metastasis. Intern Med. 2017, 56:1345-9. 10.2169\/internalmedicine.56.8545","journal-title":"Intern Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-219354","article-title":"Treatment of severe hypocalcaemia due to osteoblastic metastases in a patient with post-thyroidectomy hypoparathyroidism with (153)Sm-EDTMP","volume":"2017","author":"Kassi E","year":"2017","unstructured":"Kassi E, Kapsali I, Kokkinos M, Gogas H. Treatment of severe hypocalcaemia due to osteoblastic metastases in a patient with post-thyroidectomy hypoparathyroidism with (153)Sm-EDTMP. BMJ Case Rep. 2017, 2017:10.1136\/bcr-2017-219354","journal-title":"BMJ Case Rep"},{"key":"ref11","article-title":"Hypocalcaemia of malignancy","volume":"74","author":"Schattner A","year":"2016","unstructured":"Schattner A, Dubin I, Huber R, Gelber M. Hypocalcaemia of malignancy. Neth J Med. 2016, 74:231-9.","journal-title":"Neth J Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2010.0067","article-title":"Normal parathyroid hormone levels do not exclude permanent hypoparathyroidism after thyroidectomy","volume":"21","author":"Promberger R","year":"2011","unstructured":"Promberger R, Ott J, Kober F, Karik M, Freissmuth M, Hermann M. Normal parathyroid hormone levels do not exclude permanent hypoparathyroidism after thyroidectomy. Thyroid. 2011, 21:145-50. 10.1089\/thy.2010.0067","journal-title":"Thyroid"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.20945\/2359-3997000000549","article-title":"Hypoparathyroidism: Update of guidelines from the 2022 International Task Force","volume":"66","author":"Clarke BL","year":"2022","unstructured":"Clarke BL. Hypoparathyroidism: Update of guidelines from the 2022 International Task Force. Arch Endocrinol Metab. 2022, 66:604-10. 10.20945\/2359-3997000000549","journal-title":"Arch Endocrinol Metab"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2019-0728","article-title":"Risk factors and prognosis of bone metastases in newly diagnosed gastric cancer","volume":"16","author":"Liang C","year":"2020","unstructured":"Liang C, Chen H, Yang Z, Han C, Ren C. Risk factors and prognosis of bone metastases in newly diagnosed gastric cancer. Future Oncol. 2020, 16:733-48. 10.2217\/fon-2019-0728","journal-title":"Future Oncol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10081777","article-title":"Bone metastases from gastric cancer: what we know and how to deal with them","volume":"10","author":"Petrillo A","year":"2021","unstructured":"Petrillo A, Giunta EF, Pappalardo A, et al.. Bone metastases from gastric cancer: what we know and how to deal with them. J Clin Med. 2021, 10:1777. 10.3390\/jcm10081777","journal-title":"J Clin Med"},{"key":"ref16","doi-asserted-by":"crossref","DOI":"10.4251\/wjgo.v11.i9.686","article-title":"Tumor progression-dependent angiogenesis in gastric cancer and its potential application","volume":"11","author":"Hsieh HL","year":"2019","unstructured":"Hsieh HL, Tsai MM. Tumor progression-dependent angiogenesis in gastric cancer and its potential application. World J Gastrointest Oncol. 2019, 11:686-704.","journal-title":"World J Gastrointest Oncol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159\/000127386","article-title":"Clinical outcome of gastric cancer patients with bone marrow metastases","volume":"73","author":"Kim HS","year":"2007","unstructured":"Kim HS, Yi SY, Jun HJ, et al.. Clinical outcome of gastric cancer patients with bone marrow metastases. Oncology. 2007, 73:192-7. 10.1159\/000127386","journal-title":"Oncology"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s12288-014-0378-0","article-title":"Pancytopenia and isolated bone marrow recurrence in a case of previously resected gastric carcinoma: A rare finding","volume":"30","author":"Sehgal T","year":"2014","unstructured":"Sehgal T, Kumar N, Rastogi P, Kapoor R. Pancytopenia and isolated bone marrow recurrence in a case of previously resected gastric carcinoma: A rare finding. Indian J Hematol Blood Transfus. 2014, 30:314-6. 10.1007\/s12288-014-0378-0","journal-title":"Indian J Hematol Blood Transfus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/510183-pancytopenia-and-hypocalcemia-an-unexpected-cause","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:39:44Z","timestamp":1789025984000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/510183-pancytopenia-and-hypocalcemia-an-unexpected-cause"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,10]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.116031","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,10]]}}}