{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:05:11Z","timestamp":1789286711071,"version":"build-2803163510"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,13]]},"DOI":"10.7759\/cureus.116161","type":"journal-article","created":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:04:21Z","timestamp":1789286661000},"source":"Crossref","is-referenced-by-count":0,"title":["Integrated Clinical, Biological, and Echocardiographic Factors Independently Associated With In-Hospital Mortality in Infective Endocarditis: A Single-Centre Cohort Study From Morocco"],"prefix":"10.7759","author":[{"given":"Tariq","family":"El Karimy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiba","family":"Rizkou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joumana","family":"Elmasrioui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustapha","family":"Elhattaoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.59","article-title":"Infective endocarditis","volume":"2","author":"Holland TL","year":"2016","unstructured":"Holland TL, Baddour LM, Bayer AS, Hoen B, Miro JM, Fowler VG Jr. Infective endocarditis. Nat Rev Dis Primers. 2016, 2:16059. 10.1038\/nrdp.2016.59","journal-title":"Nat Rev Dis Primers"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-025-05034-7","article-title":"Global, regional, and national burden of endocarditis, 1990-2021: a systematic analysis of the GBD 2021 study","volume":"25","author":"Feng J","year":"2025","unstructured":"Feng J, Liu P, Li H, Chen H, Shen Q, Liu H, Hu J. Global, regional, and national burden of endocarditis, 1990-2021: a systematic analysis of the GBD 2021 study. BMC Cardiovasc Disord. 2025, 25:561. 10.1186\/s12872-025-05034-7","journal-title":"BMC Cardiovasc Disord"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2016.08.011","article-title":"Infective endocarditis in low- and middle-income countries","volume":"35","author":"Njuguna B","year":"2017","unstructured":"Njuguna B, Gardner A, Karwa R, Delahaye F. Infective endocarditis in low- and middle-income countries. Cardiol Clin. 2017, 35:153-63. 10.1016\/j.ccl.2016.08.011","journal-title":"Cardiol Clin"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl427","article-title":"Infective endocarditis: changing epidemiology and predictors of 6-month mortality: a prospective cohort study","volume":"28","author":"Hill EE","year":"2007","unstructured":"Hill EE, Herijgers P, Claus P, Vanderschueren S, Herregods MC, Peetermans WE. Infective endocarditis: changing epidemiology and predictors of 6-month mortality: a prospective cohort study. Eur Heart J. 2007, 28:196-203. 10.1093\/eurheartj\/ehl427","journal-title":"Eur Heart J"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)01206-7","article-title":"Echocardiography predicts embolic events in infective endocarditis","volume":"37","author":"Di Salvo G","year":"2001","unstructured":"Di Salvo G, Habib G, Pergola V, et al.. Echocardiography predicts embolic events in infective endocarditis. J Am Coll Cardiol. 2001, 37:1069-76. 10.1016\/S0735-1097(00)01206-7","journal-title":"J Am Coll Cardiol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90535-H","article-title":"Echocardiographic assessment of patients with infectious endocarditis: prediction of risk for complications","volume":"18","author":"Sanfilippo AJ","year":"1991","unstructured":"Sanfilippo AJ, Picard MH, Newell JB, Rosas E, Davidoff R, Thomas JD, Weyman AE. Echocardiographic assessment of patients with infectious endocarditis: prediction of risk for complications. J Am Coll Cardiol. 1991, 18:1191-9. 10.1016\/0735-1097(91)90535-H","journal-title":"J Am Coll Cardiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/heart.88.1.53","article-title":"Mortality from infective endocarditis: clinical predictors of outcome","volume":"88","author":"Wallace SM","year":"2002","unstructured":"Wallace SM, Walton BI, Kharbanda RK, Hardy R, Wilson AP, Swanton RH. Mortality from infective endocarditis: clinical predictors of outcome. Heart. 2002, 88:53-60. 10.1136\/heart.88.1.53","journal-title":"Heart"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad193","article-title":"2023 ESC guidelines for the management of endocarditis: developed by the task force on the management of endocarditis of the European Society of Cardiology (ESC) Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Nuclear Medicine (EANM)","volume":"44","author":"Delgado V","year":"2023","unstructured":"Delgado V, Ajmone Marsan N, de Waha S, et al.. 2023 ESC guidelines for the management of endocarditis: developed by the task force on the management of endocarditis of the European Society of Cardiology (ESC) Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Nuclear Medicine (EANM). Eur Heart J. 2023, 44:3948-4042. 10.1093\/eurheartj\/ehad193","journal-title":"Eur Heart J"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz620","article-title":"Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European Infective Endocarditis) registry: a prospective cohort study","volume":"40","author":"Habib G","year":"2019","unstructured":"Habib G, Erba PA, Iung B, et al.. Clinical presentation, aetiology and outcome of infective endocarditis. Results of the ESC-EORP EURO-ENDO (European Infective Endocarditis) registry: a prospective cohort study. Eur Heart J. 2019, 40:3222-32. 10.1093\/eurheartj\/ehz620","journal-title":"Eur Heart J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciad271","article-title":"The 2023 Duke-International Society for Cardiovascular Infectious Diseases criteria for infective endocarditis: updating the modified Duke criteria","volume":"77","author":"Fowler VG","year":"2023","unstructured":"Fowler VG, Durack DT, Selton-Suty C, et al.. The 2023 Duke-International Society for Cardiovascular Infectious Diseases criteria for infective endocarditis: updating the modified Duke criteria. Clin Infect Dis. 2023, 77:518-26. 10.1093\/cid\/ciad271","journal-title":"Clin Infect Dis"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S101902","article-title":"Managing infective endocarditis in the elderly: new issues for an old disease","volume":"11","author":"Forestier E","year":"2016","unstructured":"Forestier E, Fraisse T, Roubaud-Baudron C, Selton-Suty C, Pagani L. Managing infective endocarditis in the elderly: new issues for an old disease. Clin Interv Aging. 2016, 11:1199-206. 10.2147\/CIA.S101902","journal-title":"Clin Interv Aging"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4546-6","article-title":"The clinical features and prognosis of infective endocarditis in the elderly from 2007 to 2016 in a tertiary hospital in China","volume":"19","author":"Wu Z","year":"2019","unstructured":"Wu Z, Chen Y, Xiao T, Niu T, Shi Q, Xiao Y. The clinical features and prognosis of infective endocarditis in the elderly from 2007 to 2016 in a tertiary hospital in China. BMC Infect Dis. 2019, 19:937. 10.1186\/s12879-019-4546-6","journal-title":"BMC Infect Dis"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2021-319637","article-title":"Severity of anaemia and association with all-cause mortality in patients with medically managed left-sided endocarditis","volume":"108","author":"Pries-Heje MM","year":"2022","unstructured":"Pries-Heje MM, Hasselbalch RB, Wiingaard C, et al.. Severity of anaemia and association with all-cause mortality in patients with medically managed left-sided endocarditis. Heart. 2022, 108:882-8. 10.1136\/heartjnl-2021-319637","journal-title":"Heart"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/530904-integrated-clinical-biological-and-echocardiographic-factors-independently-associated-with-in-hospital-mortality-in-infective-endocarditis-a-single-centre-cohort-study-from-morocco","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T08:04:22Z","timestamp":1789286662000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/530904-integrated-clinical-biological-and-echocardiographic-factors-independently-associated-with-in-hospital-mortality-in-infective-endocarditis-a-single-centre-cohort-study-from-morocco"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,13]]},"references-count":13,"URL":"https:\/\/doi.org\/10.7759\/cureus.116161","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,13]]}}}