{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T22:04:03Z","timestamp":1789337043369,"version":"build-2803163510"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,13]]},"DOI":"10.7759\/cureus.116187","type":"journal-article","created":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T21:58:37Z","timestamp":1789336717000},"source":"Crossref","is-referenced-by-count":0,"title":["Pilsicainide Intoxication Presenting With Alternating Accelerated Idioventricular and Junctional Escape Rhythms During Acute Kidney Injury: A Case Report"],"prefix":"10.7759","author":[{"given":"Shousei","family":"Osako","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Miyauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Oketani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuru","family":"Ohishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joa.2016.03.004","article-title":"Assessment of drug-induced proarrhythmias due to pilsicainide in patients with atrial tachyarrhythmias","volume":"32","author":"Koike H","year":"2016","unstructured":"Koike H, Fujino T, Koike M, et al.. Assessment of drug-induced proarrhythmias due to pilsicainide in patients with atrial tachyarrhythmias. J Arrhythm. 2016, 32:468-73. 10.1016\/j.joa.2016.03.004","journal-title":"J Arrhythm"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1090265","article-title":"Case report: an autopsy case of pilsicainide poisoning","volume":"14","author":"Takei S","year":"2023","unstructured":"Takei S, Kinoshita H, Kumihashi M, Jamal M, Abe H, Kimura S. Case report: an autopsy case of pilsicainide poisoning. Front Pharmacol. 2023, 14:10.3389\/fphar.2023.1090265","journal-title":"Front Pharmacol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.4676-20","article-title":"Pilsicainide intoxication with neuropsychiatric symptoms treated with continuous hemodiafiltration","volume":"59","author":"Asano M","year":"2020","unstructured":"Asano M, Hayakawa T, Kato Y, Kawada K, Goto S, Branch J, Shimizu H. Pilsicainide intoxication with neuropsychiatric symptoms treated with continuous hemodiafiltration. Intern Med. 2020, 59:2191-5. 10.2169\/internalmedicine.4676-20","journal-title":"Intern Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1536\/jhj.45.1049","article-title":"A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings","volume":"45","author":"Horita Y","year":"2004","unstructured":"Horita Y, Kanaya H, Uno Y, et al.. A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings. Jpn Heart J. 2004, 45:1049-56. 10.1536\/jhj.45.1049","journal-title":"Jpn Heart J"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-252108","article-title":"Pilsicainide intoxication mimicking hyperkalemia effectively managed by prompt diagnosis and emergency haemodialysis","volume":"15","author":"Hirano Y","year":"2022","unstructured":"Hirano Y, Fujikawa H, Shibazaki S. Pilsicainide intoxication mimicking hyperkalemia effectively managed by prompt diagnosis and emergency haemodialysis. BMJ Case Rep. 2022, 15:10.1136\/bcr-2022-252108","journal-title":"BMJ Case Rep"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2014.44.2.122","article-title":"A case of sudden cardiac death due to pilsicainide-induced torsades de pointes","volume":"44","author":"Nakatani S","year":"2014","unstructured":"Nakatani S, Taniike M, Makino N, Egami Y, Shutta R, Tanouchi J, Nishino M. A case of sudden cardiac death due to pilsicainide-induced torsades de pointes. Korean Circ J. 2014, 44:122-4. 10.4070\/kcj.2014.44.2.122","journal-title":"Korean Circ J"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3918\/jsicm.17.327","article-title":"Serious polymorphic ventricular tachycardia induced by pilsicainide intoxication with hyperkalemia treated with continuous hemodiafiltration. (Article in Japanese)","volume":"17","author":"Yasuda H","year":"2010","unstructured":"Yasuda H, Mishima M, Yonemoto T, Okuyama Y. Serious polymorphic ventricular tachycardia induced by pilsicainide intoxication with hyperkalemia treated with continuous hemodiafiltration. (Article in Japanese). J Jpn Soc Intensive Care Med. 2010, 17:327-32. 10.3918\/jsicm.17.327","journal-title":"J Jpn Soc Intensive Care Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.9371","article-title":"Flecainide toxicity - clinical diagnosis and management of an urgent condition","volume":"12","author":"Bazoukis G","year":"2024","unstructured":"Bazoukis G, Efthymiou P, Yiannikourides A, et al.. Flecainide toxicity - clinical diagnosis and management of an urgent condition. Clin Case Rep. 2024, 12:10.1002\/ccr3.9371","journal-title":"Clin Case Rep"},{"key":"ref9","article-title":"KDIGO clinical practice guideline for acute kidney injury","volume":"2","author":"KDIGO Group","year":"2012","unstructured":"KDIGO Group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012, 2:1.","journal-title":"Kidney Int Suppl"},{"key":"ref10","article-title":"Accelerated idioventricular rhythm: history and chronology of the main discoveries","volume":"10","author":"Riera AR","year":"2010","unstructured":"Riera AR, Barros RB, de Sousa FD, Baranchuk A. Accelerated idioventricular rhythm: history and chronology of the main discoveries. Indian Pacing Electrophysiol J. 2010, 10:40-8.","journal-title":"Indian Pacing Electrophysiol J"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s13181-015-0483-y","article-title":"A literature review of the use of sodium bicarbonate for the treatment of QRS widening","volume":"12","author":"Bruccoleri RE","year":"2016","unstructured":"Bruccoleri RE, Burns MM. A literature review of the use of sodium bicarbonate for the treatment of QRS widening. J Med Toxicol. 2016, 12:121-9. 10.1007\/s13181-015-0483-y","journal-title":"J Med Toxicol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(95)70151-6","article-title":"ECG lead aVR versus QRS interval in predicting seizures and arrhythmias in acute tricyclic antidepressant toxicity","volume":"26","author":"Liebelt EL","year":"1995","unstructured":"Liebelt EL, Francis PD, Woolf AD. ECG lead aVR versus QRS interval in predicting seizures and arrhythmias in acute tricyclic antidepressant toxicity. Ann Emerg Med. 1995, 26:195-201. 10.1016\/S0196-0644(95)70151-6","journal-title":"Ann Emerg Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/529781-pilsicainide-intoxication-presenting-with-alternating-accelerated-idioventricular-and-junctional-escape-rhythms-during-acute-kidney-injury-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T21:58:38Z","timestamp":1789336718000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/529781-pilsicainide-intoxication-presenting-with-alternating-accelerated-idioventricular-and-junctional-escape-rhythms-during-acute-kidney-injury-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,13]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.116187","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9,13]]}}}