{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T17:00:09Z","timestamp":1761238809987},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,30]]},"DOI":"10.7759\/cureus.11789","type":"journal-article","created":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T18:58:50Z","timestamp":1606762730000},"source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Body Mass Index on the Clinicopathological and Prognostic Factors of Colorectal Cancer in Saudi Arabia"],"prefix":"10.7759","author":[{"given":"Saleh M","family":"Aldaqal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulqader A","family":"Maqbul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed  A","family":"Alhammad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aseel S","family":"Alghamdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bandar A","family":"Alharbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meshal T","family":"Alharbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar M","family":"Alhazmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasir O","family":"Zaylaee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.65","article-title":"Colorectal cancer","volume":"1","author":"Kuipers EJ","year":"2015","unstructured":"Kuipers EJ, Grady WM, Lieberman D, et al.. Colorectal cancer. Nat Rev Dis Primers. 2015, 1:15065. 10.1038\/nrdp.2015.65","journal-title":"Nat Rev Dis Primers"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.22034\/APJCP.2017.18.9.2437","article-title":"Cancer incidence in Saudi Arabia: 2012 data from the Saudi Cancer Registry","volume":"18","author":"Bazarbashi S","year":"2017","unstructured":"Bazarbashi S, Al Eid H, Minguet J. Cancer incidence in Saudi Arabia: 2012 data from the Saudi Cancer Registry. Asian Pac J Cancer Prev. 2017, 18:2437-2444. 10.22034\/APJCP.2017.18.9.2437","journal-title":"Asian Pac J Cancer Prev"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-916274","article-title":"Colorectal cancer: epidemiology, risk factors, and health services","volume":"18","author":"Amersi F","year":"2005","unstructured":"Amersi F, Agustin M, Ko CY. Colorectal cancer: epidemiology, risk factors, and health services. Clin Colon Rectal Surg. 2005, 18:133-140. 10.1055\/s-2005-916274","journal-title":"Clin Colon Rectal Surg"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60460-8","article-title":"Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013","volume":"384","author":"Ng M","year":"2014","unstructured":"Ng M, Fleming T, Robinson M, et al.. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014, 384:766-781. 10.1016\/S0140-6736(14)60460-8","journal-title":"Lancet"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-015-1306-y","article-title":"Obesity as a risk factor in cancer: a national consensus of the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology","volume":"17","author":"Goday A","year":"2015","unstructured":"Goday A, Barneto I, Garc\u00eda-Almeida JM, et al.. Obesity as a risk factor in cancer: a national consensus of the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology. Clin Transl Oncol. 2015, 17:763-771. 10.1007\/s12094-015-1306-y","journal-title":"Clin Transl Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-304701","article-title":"Obesity and colorectal cancer","volume":"62","author":"Bardou M","year":"2013","unstructured":"Bardou M, Barkun AN, Martel M. Obesity and colorectal cancer. Gut. 2013, 62:933-947. 10.1136\/gutjnl-2013-304701","journal-title":"Gut"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60269-X","article-title":"Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies","volume":"371","author":"Renehan AG","year":"2008","unstructured":"Renehan AG, Tyson M, Egger M, et al.. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet. 2008, 371:569-578. 10.1016\/S0140-6736(08)60269-X","journal-title":"Lancet"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31100","article-title":"Body fatness at an early age and risk of colorectal cancer","volume":"142","author":"Hidayat K","year":"2018","unstructured":"Hidayat K, Yang C-M, Shi B-M. Body fatness at an early age and risk of colorectal cancer. Int J Cancer. 2018, 142:729-740. 10.1002\/ijc.31100","journal-title":"Int J Cancer"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.068189","article-title":"Effect of physical activity and body size on survival after diagnosis with colorectal cancer","volume":"55","author":"Haydon AM","year":"2006","unstructured":"Haydon AM, Macinnis RJ, English DR, et al.. Effect of physical activity and body size on survival after diagnosis with colorectal cancer. Gut. 2006, 55:62-67. 10.1136\/gut.2005.068189","journal-title":"Gut"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-017-4682-z","article-title":"BMI is a risk factor for colorectal cancer mortality","volume":"62","author":"Shaukat A","year":"2017","unstructured":"Shaukat A, Dostal A, Menk J, et al.. BMI is a risk factor for colorectal cancer mortality. Dig Dis Sci. 2017, 62:2511-2517. 10.1007\/s10620-017-4682-z","journal-title":"Dig Dis Sci"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2017.09.004","article-title":"Meta-analysis of the clinicopathological characteristics and peri-operative outcomes of colorectal cancer in obese patients","volume":"51","author":"Rogers AC","year":"2017","unstructured":"Rogers AC, Handelman GS, Solon JG, et al.. Meta-analysis of the clinicopathological characteristics and peri-operative outcomes of colorectal cancer in obese patients. Cancer Epidemiol. 2017, 51:23-29. 10.1016\/j.canep.2017.09.004","journal-title":"Cancer Epidemiol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.136531","article-title":"Prognostic relevance of prediagnostic weight loss and overweight at diagnosis in patients with colorectal cancer","volume":"104","author":"Walter V","year":"2016","unstructured":"Walter V, Jansen L, Hoffmeister M, et al.. Prognostic relevance of prediagnostic weight loss and overweight at diagnosis in patients with colorectal cancer. Am J Clin Nutr. 2016, 104:1110-1120. 10.3945\/ajcn.116.136531","journal-title":"Am J Clin Nutr"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-014-0435-x","article-title":"Postdiagnosis body mass index and risk of mortality in colorectal cancer survivors: a prospective study and meta-analysis","volume":"25","author":"Schlesinger S","year":"2014","unstructured":"Schlesinger S, Siegert S, Koch M, et al.. Postdiagnosis body mass index and risk of mortality in colorectal cancer survivors: a prospective study and meta-analysis. Cancer Causes Control. 2014, 25:1407-1418. 10.1007\/s10552-014-0435-x","journal-title":"Cancer Causes Control"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0000000000000447","article-title":"Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma: a large prospective cohort study in Norway","volume":"27","author":"Lu Y","year":"2016","unstructured":"Lu Y, Ness-Jensen E, Martling A, et al.. Anthropometry-based obesity phenotypes and risk of colorectal adenocarcinoma: a large prospective cohort study in Norway. Epidemiology. 2016, 27:423-432. 10.1097\/EDE.0000000000000447","journal-title":"Epidemiology"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0985-4","article-title":"The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM","volume":"17","author":"Edge SB","year":"2010","unstructured":"Edge SB, Compton CC. The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM. Ann Surg Oncol. 2010, 17:1471-1474. 10.1245\/s10434-010-0985-4","journal-title":"Ann Surg Oncol"},{"key":"ref16","article-title":"Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee","volume":"854","year":"1995","unstructured":"Physical status. the use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser. 1995, 854:1-452.","journal-title":"World Health Organ Tech Rep Ser"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2012.05.009","article-title":"Nutritional status, cachexia and survival in patients with advanced colorectal carcinoma. Different assessment criteria for nutritional status provide unequal results","volume":"32","author":"Thoresen L","year":"2013","unstructured":"Thoresen L, Frykholm G, Lydersen S, et al.. Nutritional status, cachexia and survival in patients with advanced colorectal carcinoma. Different assessment criteria for nutritional status provide unequal results. Clin Nutr. 2013, 32:65-72. 10.1016\/j.clnu.2012.05.009","journal-title":"Clin Nutr"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-11-293","article-title":"Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study","volume":"11","author":"Br\u00e4ndstedt J","year":"2013","unstructured":"Br\u00e4ndstedt J, Wangefjord S, Borgquist S, et al.. Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study. J Transl Med. 2013, 11:293. 10.1186\/1479-5876-11-293","journal-title":"J Transl Med"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S2173-5077(10)70162-9","article-title":"The impact of obesity on the histopathological characteristics of colorectal tumours. An observational study","volume":"87","author":"Garc\u00eda-Oria Serrano MJ","year":"2010","unstructured":"Garc\u00eda-Oria Serrano MJ, Armengol Carrasco M, Ortiz R, et al.. The impact of obesity on the histopathological characteristics of colorectal tumours. An observational study. Cirug\u00eda Espa\u00f1ola. 2010, 87:33-38. 10.1016\/S2173-5077(10)70162-9","journal-title":"Cirug\u00eda Espa\u00f1ola"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju177","article-title":"Cancer prognosis: role of BMI and fat tissue","volume":"106","author":"Azvolinsky A","year":"2014","unstructured":"Azvolinsky A. Cancer prognosis: role of BMI and fat tissue. J Natl Cancer Inst. 2014, 106:dju177. 10.1093\/jnci\/dju177","journal-title":"J Natl Cancer Inst"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1503\/cjs.004414","article-title":"Is obesity associated with advanced stage or grade of colon cancer? Canadian journal of surgery","volume":"58","author":"Neumann K","year":"2015","unstructured":"Neumann K, Mahmud SM, McKay, et al.. Is obesity associated with advanced stage or grade of colon cancer? Canadian journal of surgery. Can J Surg. 2015, 58:140-142. 10.1503\/cjs.004414","journal-title":"Can J Surg"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/2042-6410-3-23","article-title":"Gender, anthropometric factors and risk of colorectal cancer with particular reference to tumour location and TNM stage: a cohort study","volume":"3","author":"Br\u00e4ndstedt J","year":"2012","unstructured":"Br\u00e4ndstedt J, Wangefjord S, Nodin B, et al.. Gender, anthropometric factors and risk of colorectal cancer with particular reference to tumour location and TNM stage: a cohort study. Biol Sex Differ. 2012, 3:23. 10.1186\/2042-6410-3-23","journal-title":"Biol Sex Differ"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-014-0450-y","article-title":"Association of obesity and overweight with overall survival in colorectal cancer patients: a meta-analysis of 29 studies","volume":"25","author":"Wu S","year":"2014","unstructured":"Wu S, Liu J, Wang X, et al.. Association of obesity and overweight with overall survival in colorectal cancer patients: a meta-analysis of 29 studies. Cancer Causes Control. 2014, 25:1489-1502. 10.1007\/s10552-014-0450-y","journal-title":"Cancer Causes Control"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djk092","article-title":"Lymph node evaluation and survival after curative resection of colon cancer: systematic review","volume":"99","author":"Chang GJ","year":"2007","unstructured":"Chang GJ, Rodriguez-Bigas MA, Skibber JM, et al.. Lymph node evaluation and survival after curative resection of colon cancer: systematic review. J Natl Cancer Inst. 2007, 99:433-441. 10.1093\/jnci\/djk092","journal-title":"J Natl Cancer Inst"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11544","article-title":"Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma","volume":"98","author":"Meyerhardt JA","year":"2003","unstructured":"Meyerhardt JA, Catalano PJ, Haller DG, et al.. Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma. Cancer. 2003, 98:484-495. 10.1002\/cncr.11544","journal-title":"Cancer"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1097\/CEJ.0b013e328360f434","article-title":"Body mass index, physical activity, and colorectal cancer by anatomical subsites: a systematic review and meta-analysis of cohort studies","volume":"22","author":"Robsahm TE","year":"2013","unstructured":"Robsahm TE, Aagnes B, Hjart\u00e5ker A, et al.. Body mass index, physical activity, and colorectal cancer by anatomical subsites: a systematic review and meta-analysis of cohort studies. Eur J Cancer Prev. 2013, 22:492-505. 10.1097\/CEJ.0b013e328360f434","journal-title":"Eur J Cancer Prev"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200210000-00003","article-title":"A new TNM staging strategy for node-positive (stage III) colon cancer: an analysis of 50,042 patients","volume":"236","author":"Greene FL","year":"2002","unstructured":"Greene FL, Stewart AK, Norton HJ. A new TNM staging strategy for node-positive (stage III) colon cancer: an analysis of 50,042 patients. Ann Surg. 2002, 236:416-421. 10.1097\/00000658-200210000-00003","journal-title":"Ann Surg"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602013340503","article-title":"Serum immunoreactive-leptin concentrations in normal-weight and obese humans","volume":"334","author":"Considine RV","year":"1996","unstructured":"Considine RV, Sinha MK, Heiman ML, et al.. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med. 1996, 334:292-295. 10.1056\/NEJM199602013340503","journal-title":"N Engl J Med"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2006.041004","article-title":"Overexpression of the obesity hormone leptin in human colorectal cancer","volume":"60","author":"Koda M","year":"2007","unstructured":"Koda M, Sulkowska M, Kanczuga-Koda L, et al.. Overexpression of the obesity hormone leptin in human colorectal cancer. J Clin Pathol. 2007, 60:902-906. 10.1136\/jcp.2006.041004","journal-title":"J Clin Pathol"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802606","article-title":"BMI and waist circumference as predictors of lifetime colon cancer risk in Framingham Study adults","volume":"28","author":"Moore LL","year":"2004","unstructured":"Moore LL, Bradlee ML, Singer MR, et al.. BMI and waist circumference as predictors of lifetime colon cancer risk in Framingham Study adults. Int J Obes Relat Metab Disord. 2004, 28:559-567. 10.1038\/sj.ijo.0802606","journal-title":"Int J Obes Relat Metab Disord"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/45945-the-impact-of-body-mass-index-on-the-clinicopathological-and-prognostic-factors-of-colorectal-cancer-in-saudi-arabia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:21:12Z","timestamp":1707506472000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/45945-the-impact-of-body-mass-index-on-the-clinicopathological-and-prognostic-factors-of-colorectal-cancer-in-saudi-arabia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,30]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.11789","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11,30]]}}}