{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T13:21:17Z","timestamp":1721827277791},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,3]]},"DOI":"10.7759\/cureus.12440","type":"journal-article","created":{"date-parts":[[2021,1,3]],"date-time":"2021-01-03T11:43:16Z","timestamp":1609674196000},"source":"Crossref","is-referenced-by-count":4,"title":["Risk Factors and Complications Among Pediatric Patients With Sickle Cell Anemia: A Single Tertiary Center Retrospective Study"],"prefix":"10.7759","author":[{"given":"Fatma","family":"Alzahrani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anas M","family":"Fallatah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatimah M","family":"Al-Haddad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahad T","family":"Khayyat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wasayf M","family":"AlMehmadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bashaier G","family":"AlQahtani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rawabi S","family":"Alamri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1510865","article-title":"Sickle cell disease","volume":"376","author":"Piel FB","year":"2017","unstructured":"Piel FB, Steinberg MH, Rees DC. Sickle cell disease. N Engl J Med. 2017, 376:1561-73. 10.1056\/NEJMra1510865","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24175","article-title":"A global perspective on sickle cell disease","volume":"59","author":"Aygun B","year":"2012","unstructured":"Aygun B, Odame I. A global perspective on sickle cell disease. Pediatr Blood Cancer. 2012, 59:386-90. 10.1002\/pbc.24175","journal-title":"Pediatr Blood Cancer"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/198492b0","article-title":"Distribution of sickle-cell hemoglobin in Saudi Arabia","volume":"198","author":"Lehmann H","year":"1963","unstructured":"Lehmann H, Maranjian G, Mourant AE. Distribution of sickle-cell hemoglobin in Saudi Arabia. Nature. 1963, 198:492-3. 10.1038\/198492b0","journal-title":"Nature"},{"key":"ref4","article-title":"The prevalence of sickle cell disease in Saudi children and adolescents. A community-based survey","volume":"29","author":"Al-Qurashi MM","year":"2008","unstructured":"Al-Qurashi MM, El-Mouzan MI, Al-Herbish AS, Al-Salloum AA, Al-Omar AA. The prevalence of sickle cell disease in Saudi children and adolescents. A community-based survey. Saudi Med J. 2008, 29:1480-3.","journal-title":"Saudi Med J"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.21767\/2386-5180.1000226","article-title":"Prevalence of complications of sickle cell disease at Makkah Al-Mukaramah, Saudi Arabia, 2017","volume":"6","author":"Alkot M","year":"2018","unstructured":"Alkot M, Almaghrabi WA, Al-Najdi N, Al Otaibi M, Shatla M, Abdelbaki H. Prevalence of complications of sickle cell disease at Makkah Al-Mukaramah, Saudi Arabia, 2017. Ann Clin Lab Res. 2018, 6:226. 10.21767\/2386-5180.1000226","journal-title":"Ann Clin Lab Res"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1542\/hpeds.2014-0184","article-title":"Clinical and geographic characterization of 30-day readmissions in pediatric sickle cell crisis patients","volume":"5","author":"McMillan JE","year":"2015","unstructured":"McMillan JE, Meier ER, Winer JC, Coco M, Daymont M, Long S, Jacobs BR. Clinical and geographic characterization of 30-day readmissions in pediatric sickle cell crisis patients. Hosp Pediatr. 2015, 5:423-31. 10.1542\/hpeds.2014-0184","journal-title":"Hosp Pediatr"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12411","article-title":"Sickle cell disease in children: chronic complications and search of predictive factors for adverse outcomes","volume":"94","author":"Silva IV","year":"2015","unstructured":"Silva IV, Reis AF, Palar\u00e9 MJ, Ferr\u00e3o A, Rodrigues T, Morais A. Sickle cell disease in children: chronic complications and search of predictive factors for adverse outcomes. Eur J Haematol. 2015, 94:157-61. 10.1111\/ejh.12411","journal-title":"Eur J Haematol"},{"key":"ref8","unstructured":"WHO. obesity and overweight. (2020). Accessed: August 15, 2020: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight."},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jegh.2017.12.001","article-title":"Distribution of hemoglobinopathy disorders in Saudi Arabia based on data from the premarital screening and genetic counseling program, 2011-2015","volume":"7","author":"Alsaeed ES","year":"2018","unstructured":"Alsaeed ES, Farhat GN, Assiri AM, et al.. Distribution of hemoglobinopathy disorders in Saudi Arabia based on data from the premarital screening and genetic counseling program, 2011-2015. J Epidemiol Glob Health. 2018, 7:S41-7. 10.1016\/j.jegh.2017.12.001","journal-title":"J Epidemiol Glob Health"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/0256-4947.81540","article-title":"Epidemiology of sickle cell disease in Saudi Arabia","volume":"31","author":"Jastaniah W","year":"2011","unstructured":"Jastaniah W. Epidemiology of sickle cell disease in Saudi Arabia. Ann Saudi Med. 2011, 31:289-93. 10.4103\/0256-4947.81540","journal-title":"Ann Saudi Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2008.07.050","article-title":"Comparisons of high versus low emergency department utilizers in sickle cell disease","volume":"53","author":"Aisiku IP","year":"2009","unstructured":"Aisiku IP, Smith WR, McClish DK, et al.. Comparisons of high versus low emergency department utilizers in sickle cell disease. Ann Emerg Med. 2009, 53:587-93. 10.1016\/j.annemergmed.2008.07.050","journal-title":"Ann Emerg Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.378","article-title":"Acute care utilization and rehospitalizations for sickle cell disease","volume":"303","author":"Brousseau DC","year":"2010","unstructured":"Brousseau DC, Owens PL, Mosso AL, Panepinto JA, Steiner CA. Acute care utilization and rehospitalizations for sickle cell disease. JAMA. 2010, 303:1288-94. 10.1001\/jama.2010.378","journal-title":"JAMA"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00000446-199903000-00033","article-title":"Sickle cell disease. Do you doubt your patient's pain?","volume":"99","author":"Gorman K","year":"1999","unstructured":"Gorman K. Sickle cell disease. Do you doubt your patient's pain?. Am J Nurs. 1999, 99:38-43. 10.1097\/00000446-199903000-00033","journal-title":"Am J Nurs"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-07-100719","article-title":"Prediction of adverse outcomes in children with sickle cell anemia: a study of the Dallas Newborn Cohort","volume":"111","author":"Quinn CT","year":"2008","unstructured":"Quinn CT, Lee NJ, Shull EP, Ahmad N, Rogers ZR, Buchanan GR. Prediction of adverse outcomes in children with sickle cell anemia: a study of the Dallas Newborn Cohort. Blood. 2008, 111:544-8. 10.1182\/blood-2007-07-100719","journal-title":"Blood"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/adc.82.3.204","article-title":"Height and weight reference curves for homozygous sickle cell disease","volume":"82","author":"Thomas PW","year":"2000","unstructured":"Thomas PW, Singhal A, Hemmings-Kelly M, Serjeant GR. Height and weight reference curves for homozygous sickle cell disease. Arch Dis Child. 2000, 82:204-8. 10.1136\/adc.82.3.204","journal-title":"Arch Dis Child"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9343(96)00407-x","article-title":"Natural history of blood pressure in sickle cell disease: risks for stroke and death associated with relative hypertension in sickle cell anemia","volume":"102","author":"Pegelow CH","year":"1997","unstructured":"Pegelow CH, Colangelo L, Steinberg M, Wright EC, Smith J, Phillips G, Vichinsky E. Natural history of blood pressure in sickle cell disease: risks for stroke and death associated with relative hypertension in sickle cell anemia. Am J Med. 1997, 102:171-7. 10.1016\/s0002-9343(96)00407-x","journal-title":"Am J Med"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066004","article-title":"Male gender, increased blood viscosity, body mass index and triglyceride levels are independently associated with systemic relative hypertension in sickle cell anemia","volume":"8","author":"Lamarre Y","year":"2013","unstructured":"Lamarre Y, Lalanne-Mistrih ML, Romana M, et al.. Male gender, increased blood viscosity, body mass index and triglyceride levels are independently associated with systemic relative hypertension in sickle cell anemia. PloS One. 2013, 8:e66004. 10.1371\/journal.pone.0066004","journal-title":"PloS One"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21699","article-title":"The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: a 17.5 year follow-up","volume":"85","author":"Steinberg MH","year":"2010","unstructured":"Steinberg MH, McCarthy WF, Castro O, et al.. The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: a 17.5 year follow-up. Am J Hematol. 2010, 85:403-8. 10.1002\/ajh.21699","journal-title":"Am J Hematol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.2165\/00128072-200103110-00002","article-title":"Prevention and management of infection in children with sickle cell anaemia","volume":"3","author":"Wong WY","year":"2001","unstructured":"Wong WY. Prevention and management of infection in children with sickle cell anaemia. Paediatr Drugs. 2001, 3:793-801. 10.2165\/00128072-200103110-00002","journal-title":"Paediatr Drugs"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1086\/516781","article-title":"Incidence of invasive pneumococcal disease among individuals with sickle cell disease before and after the introduction of the pneumococcal conjugate vaccine","volume":"44","author":"Halasa NB","year":"2007","unstructured":"Halasa NB, Shankar SM, Talbot TR, et al.. Incidence of invasive pneumococcal disease among individuals with sickle cell disease before and after the introduction of the pneumococcal conjugate vaccine. Clin Infect Dis. 2007, 44:1428-33. 10.1086\/516781","journal-title":"Clin Infect Dis"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.088807","article-title":"Bacteraemia in homozygous sickle cell disease in Africa: is pneumococcal prophylaxis justified?","volume":"92","author":"Kizito ME","year":"2007","unstructured":"Kizito ME, Mworozi E, Ndugwa C, Serjeant GR. Bacteraemia in homozygous sickle cell disease in Africa: is pneumococcal prophylaxis justified?. Arch Dis Child. 2007, 92:21-3. 10.1136\/adc.2005.088807","journal-title":"Arch Dis Child"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2008.545","article-title":"Sickle cell disease in children: differentiating osteomyelitis from vaso-occlusive crisis","volume":"163","author":"Berger E","year":"2009","unstructured":"Berger E, Saunders N, Wang L, Friedman JN. Sickle cell disease in children: differentiating osteomyelitis from vaso-occlusive crisis. Arch Pediatr Adolesc Med. 2009, 163:251-5. 10.1001\/archpediatrics.2008.545","journal-title":"Arch Pediatr Adolesc Med"},{"key":"ref23","article-title":"Osteomyelitis in sickle cell disease","volume":"13","author":"Piehl FC","year":"1993","unstructured":"Piehl FC, Davis RJ, Prugh SI. Osteomyelitis in sickle cell disease. J Pediatr Orthop. 1993, 13:225-7.","journal-title":"J Pediatr Orthop"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1097\/00006565-200102000-00018","article-title":"Differentiating osteomyelitis from bone infarction in sickle cell disease","volume":"17","author":"Wong AL","year":"2001","unstructured":"Wong AL, Sakamoto KM, Johnson EE. Differentiating osteomyelitis from bone infarction in sickle cell disease. Pediatr Emerg Care. 2001, 17:60-3. 10.1097\/00006565-200102000-00018","journal-title":"Pediatr Emerg Care"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.4103\/joah.joah_67_19","article-title":"Epidemiology and characteristics of sickle cell patients admitted to hospitals in Jazan region, Saudi Arabia","volume":"11","author":"Hazzazi AA","year":"2020","unstructured":"Hazzazi AA, Ageeli MH, Alfaqih AM, Jaafari AA, Malhan HM, Bakkar MM. Epidemiology and characteristics of sickle cell patients admitted to hospitals in Jazan region, Saudi Arabia. J Appl Hematol. 2020, 11:10-14. 10.4103\/joah.joah_67_19","journal-title":"J Appl Hematol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-09-551564","article-title":"How I treat and manage strokes in sickle cell disease","volume":"125","author":"Kassim AA","year":"2015","unstructured":"Kassim AA, Galadanci NA, Pruthi S, DeBaun MR. How I treat and manage strokes in sickle cell disease. Blood. 2015, 125:3401-10. 10.1182\/blood-2014-09-551564","journal-title":"Blood"},{"key":"ref27","doi-asserted-by":"crossref","DOI":"10.1542\/peds.97.6.864","article-title":"Cognitive functioning and brain magnetic resonance imaging in children with sickle cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease","volume":"97","author":"Armstrong FD","year":"1996","unstructured":"Armstrong FD, Thompson RJ Jr, Wang W, et al.. Cognitive functioning and brain magnetic resonance imaging in children with sickle cell disease. Neuropsychology Committee of the Cooperative Study of Sickle Cell Disease. Pediatrics. 1996, 97:864-70.","journal-title":"Pediatrics"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.22103","article-title":"Increased prevalence of osteonecrosis of the femoral head in children and adolescents with sickle-cell disease","volume":"86","author":"Mahadeo KM","year":"2011","unstructured":"Mahadeo KM, Oyeku S, Taragin B, Rajpathak SN, Moody K, Santizo R, Driscoll MC. Increased prevalence of osteonecrosis of the femoral head in children and adolescents with sickle-cell disease. Am J Hematol. 2011, 86:806-8. 10.1002\/ajh.22103","journal-title":"Am J Hematol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjhh.2016.09.009","article-title":"Cholelithiasis and its complications in sickle cell disease in a university hospital","volume":"39","author":"Martins RA","year":"2017","unstructured":"Martins RA, Soares RS, Vito FB, Barbosa VF, Silva SS, Moraes-Souza H, Martins PR. Cholelithiasis and its complications in sickle cell disease in a university hospital. Rev Bras Hematol Hemoter. 2017, 39:28-31. 10.1016\/j.bjhh.2016.09.009","journal-title":"Rev Bras Hematol Hemoter"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2008.10.015","article-title":"Laparoscopic cholecystectomy in sickle cell disease patients: does operating time matter?","volume":"7","author":"Dan D","year":"2009","unstructured":"Dan D, Seetahal S, Harnanan D, Singh Y, Hariharan S, Naraynsingh V. Laparoscopic cholecystectomy in sickle cell disease patients: does operating time matter?. Int J Surg. 2009, 7:70-3. 10.1016\/j.ijsu.2008.10.015","journal-title":"Int J Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/43954-risk-factors-and-complications-among-pediatric-patients-with-sickle-cell-anemia-a-single-tertiary-center-retrospective-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:27:24Z","timestamp":1707506844000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/43954-risk-factors-and-complications-among-pediatric-patients-with-sickle-cell-anemia-a-single-tertiary-center-retrospective-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,3]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.12440","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1,3]]}}}