{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T11:45:26Z","timestamp":1771674326270,"version":"3.50.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,23]]},"DOI":"10.7759\/cureus.13521","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T01:00:39Z","timestamp":1614128439000},"source":"Crossref","is-referenced-by-count":6,"title":["Acute Upper Gastrointestinal Bleeding in Hexagenerians or Older (\u226560 Years) Versus Younger (&lt;60 Years) Patients: Clinico-Endoscopic Profile and Outcome"],"prefix":"10.7759","author":[{"given":"Rajpal S","family":"Yadav","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payal","family":"Bargujar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans R","family":"Pahadiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul K","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitendra","family":"Upadhyay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alok","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoj","family":"Lakhotia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l536","article-title":"Management of acute upper gastrointestinal bleeding","volume":"364","author":"Stanley AJ","year":"2019","unstructured":"Stanley AJ, Laine L. Management of acute upper gastrointestinal bleeding. BMJ. 2019, 364:1536. 10.1136\/bmj.l536","journal-title":"BMJ"},{"key":"ref2","article-title":"Epidemiology of hospitalization for acute upper gastrointestinal hemorrhage: a population-based study","volume":"90","author":"Longstreth GF","year":"1995","unstructured":"Longstreth GF. Epidemiology of hospitalization for acute upper gastrointestinal hemorrhage: a population-based study. Am J Gastroenterol. 1995, 90:206-10.","journal-title":"Am J Gastroenterol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07517.x","article-title":"Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993\/1994 and 2000","volume":"98","author":"van Leerdam ME","year":"2003","unstructured":"van Leerdam ME, Vreeburg EM, Rauws EA, et al.. Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993\/1994 and 2000. Am J Gastroenterol. 2003, 98:1494-9. 10.1111\/j.1572-0241.2003.07517.x","journal-title":"Am J Gastroenterol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200402000-00009","article-title":"Changes in aetiology and clinical outcome of acute upper gastrointestinal bleeding during the last 15 years","volume":"16","author":"Thomopoulos KC","year":"2004","unstructured":"Thomopoulos KC, Vagenas KA, Vagianos CE, Margaritis VG, Blikas AP, Katsakoulis EC, Nikolopoulou VN. Changes in aetiology and clinical outcome of acute upper gastrointestinal bleeding during the last 15 years. Eur J Gastroenterol Hepatol. 2004, 16:82. 10.1097\/00042737-200402000-00009","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.6999.222","article-title":"Incidence of and mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. Steering Committee and members of the National Audit of Acute Upper Gastrointestinal Haemorrhage","volume":"311","author":"Rockall TA","year":"1995","unstructured":"Rockall TA, Logan RF, Devlin HB, Northfield TC. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. Steering Committee and members of the National Audit of Acute Upper Gastrointestinal Haemorrhage. BMJ. 1995, 311:222-6. 10.1136\/bmj.311.6999.222","journal-title":"BMJ"},{"key":"ref6","article-title":"Acute upper gastrointestinal haemorrhage in patients aged 80 years or more","volume":"68","author":"Cooper BT","year":"1988","unstructured":"Cooper BT, Weston CF, Neumann CS. Acute upper gastrointestinal haemorrhage in patients aged 80 years or more. Q J Med. 1988, 68:765-74.","journal-title":"Q J Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-4356(01)00461-9","article-title":"Incidence of serious upper gastrointestinal bleeding\/perforation in the general population: review of epidemiologic studies","volume":"55","author":"Hernandez-Diaz S","year":"2002","unstructured":"Hernandez-Diaz S, Rodriguez LA. Incidence of serious upper gastrointestinal bleeding\/perforation in the general population: review of epidemiologic studies. J Clin Epidemiol. 2002, 55:157-63. 10.1016\/s0895-4356(01)00461-9","journal-title":"J Clin Epidemiol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.4.460","article-title":"Recent trends in admissions and mortality due to peptic ulcer in England: increasing frequency of haemorrhage among older subjects","volume":"50","author":"Higham J","year":"2002","unstructured":"Higham J, Kang JY, Majeed A. Recent trends in admissions and mortality due to peptic ulcer in England: increasing frequency of haemorrhage among older subjects. Gut. 2002, 50:460-4. 10.1136\/gut.50.4.460","journal-title":"Gut"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v11.i2.68","article-title":"Role of endoscopy in acute gastrointestinal bleeding in real clinical practice: an evidence-based review","volume":"11","author":"Jung K","year":"2019","unstructured":"Jung K, Moon W. Role of endoscopy in acute gastrointestinal bleeding in real clinical practice: an evidence-based review. World J Gastrointest Endosc. 2019, 11:68-83. 10.4253\/wjge.v11.i2.68","journal-title":"World J Gastrointest Endosc"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-152-2-201001190-00009","article-title":"International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding","volume":"152","author":"Barkun AN","year":"2010","unstructured":"Barkun AN, Bardou M, Kuipers EJ, et al.. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010, 152:101-13. 10.7326\/0003-4819-152-2-201001190-00009","journal-title":"Ann Intern Med"},{"key":"ref11","article-title":"Diagnosis and management of upper gastrointestinal bleeding","volume":"85","author":"Wilkins T","year":"2012","unstructured":"Wilkins T, Khan N, Nabh A, Schade RR. Diagnosis and management of upper gastrointestinal bleeding. Am Fam Physician. 2012, 85:469-76.","journal-title":"Am Fam Physician"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-018-00930-7","article-title":"Acute upper gastrointestinal bleed: an audit of the causes and outcomes from a tertiary care center in eastern India","volume":"38","author":"Banerjee A","year":"2019","unstructured":"Banerjee A, Bishnu S, Dhali GK. Acute upper gastrointestinal bleed: an audit of the causes and outcomes from a tertiary care center in eastern India. Indian J Gastroenterol. 2019, 38:190-202. 10.1007\/s12664-018-00930-7","journal-title":"Indian J Gastroenterol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.4103\/jmh.JMH_86_17","article-title":"Etiological and endoscopic profile of middle aged and elderly patients with upper gastrointestinal bleeding in a Tertiary Care Hospital in North India: a retrospective analysis","volume":"8","author":"Mahajan P","year":"2017","unstructured":"Mahajan P, Chandail VS. Etiological and endoscopic profile of middle aged and elderly patients with upper gastrointestinal bleeding in a Tertiary Care Hospital in North India: a retrospective analysis. J Mid-Life Health. 2017, 8:137-41. 10.4103\/jmh.JMH_86_17","journal-title":"J Mid-Life Health"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.7869\/tg.2012.85","article-title":"Spectrum of upper gastrointestinal hemorrhage in coastal Odisha","volume":"34","author":"Singh SP","year":"2013","unstructured":"Singh SP, Panigrahi MK. Spectrum of upper gastrointestinal hemorrhage in coastal Odisha. Trop Gastroenterol. 2013, 34:14-7. 10.7869\/tg.2012.85","journal-title":"Trop Gastroenterol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/gut.38.3.316","article-title":"Risk assessment after acute upper gastrointestinal haemorrhage","volume":"38","author":"Rockall TA","year":"1996","unstructured":"Rockall TA, Logan RF, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal haemorrhage. Gut. 1996, 38:316-21. 10.1136\/gut.38.3.316","journal-title":"Gut"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02816-6","article-title":"A risk score to predict need for treatment for upper gastrointestinal haemorrhage","volume":"356","author":"Blatchford O","year":"2000","unstructured":"Blatchford O, Murray W, Blatchford M. A risk score to predict need for treatment for upper gastrointestinal haemorrhage. Lancet. 2000, 356:1318-21. 10.1016\/S0140-6736(00)02816-6","journal-title":"Lancet"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-101-4-538","article-title":"Double-contrast barium meal and upper gastrointestinal endoscopy. A comparative study","volume":"101","author":"Dooley CP","year":"1984","unstructured":"Dooley CP, Larson AW, Stace NH, et al.. Double-contrast barium meal and upper gastrointestinal endoscopy. A comparative study. Ann Intern Med. 1984, 101:538-45. 10.7326\/0003-4819-101-4-538","journal-title":"Ann Intern Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.carj.2012.08.001","article-title":"Acute gastrointestinal hemorrhage: radiologic diagnosis and management","volume":"64","author":"Jaskolka JD","year":"2013","unstructured":"Jaskolka JD, Binkhamis S, Prabhudesai V, Chawla TP. Acute gastrointestinal hemorrhage: radiologic diagnosis and management. Can Assoc Radiol J. 2013, 64:90-100. 10.1016\/j.carj.2012.08.001","journal-title":"Can Assoc Radiol J"},{"key":"ref19","article-title":"Clinical profile, severity and outcome of acute upper gastrointestinal bleeding in elderly patients compared to non-elderly patients: a prospective observational study","volume":"67","author":"Sourabh S","year":"2019","unstructured":"Sourabh S, Sharma N, Sharma R, et al.. Clinical profile, severity and outcome of acute upper gastrointestinal bleeding in elderly patients compared to non-elderly patients: a prospective observational study. J Assoc Physicians India. 2019, 67:30-2.","journal-title":"J Assoc Physicians India"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-7-8","article-title":"Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study","volume":"7","author":"Christensen S","year":"2007","unstructured":"Christensen S, Riis A, Norgaard M, Sorensen HT, Thomsen RW. Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study. BMC Geriatr. 2007, 7:8. 10.1186\/1471-2318-7-8","journal-title":"BMC Geriatr"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i32.3724","article-title":"Characteristics and outcomes of acute upper gastrointestinal bleeding after therapeutic endoscopy in the elderly","volume":"17","author":"Charatcharoenwitthaya P","year":"2011","unstructured":"Charatcharoenwitthaya P, Pausawasdi N, Laosanguaneak N, Bubthamala J, Tanwandee T, Leelakusolvong S. Characteristics and outcomes of acute upper gastrointestinal bleeding after therapeutic endoscopy in the elderly. World J Gastroenterol. 2011, 17:3724-32. 10.3748\/wjg.v17.i32.3724","journal-title":"World J Gastroenterol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.4047","article-title":"Acute upper gastrointestinal bleeding in oct\u03bfgenarians: clinical outcome and factors related to mortality","volume":"14","author":"Theocharis GJ","year":"2008","unstructured":"Theocharis GJ, Arvaniti V, Assimakopoulos SF, Thomopoulos KC, Xourgias V, Mylonakou I, Nikolopoulou VN. Acute upper gastrointestinal bleeding in oct\u03bfgenarians: clinical outcome and factors related to mortality. World J Gastroenterol. 2008, 14:4047-53. 10.3748\/wjg.14.4047","journal-title":"World J Gastroenterol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.228437","article-title":"Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit","volume":"60","author":"Hearnshaw SA","year":"2011","unstructured":"Hearnshaw SA, Logan RF, Lowe D, Travis SP, Murphy MF, Palmer KR. Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit. Gut. 2011, 60:1327-35. 10.1136\/gut.2010.228437","journal-title":"Gut"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05541.x","article-title":"Prospective validation of the Rockall Scoring system for upper GI haemorrhages in subgroup of patients with varices and peptic ulcers","volume":"97","author":"Sanders DS","year":"2002","unstructured":"Sanders DS, Carter MJ, Goodchap RJ, Cross SS, Gleeson DC, Lobo AJ. Prospective validation of the Rockall Scoring system for upper GI haemorrhages in subgroup of patients with varices and peptic ulcers. Am J Gastroenterol. 2002, 97:630-35. 10.1111\/j.1572-0241.2002.05541.x","journal-title":"Am J Gastroenterol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/51886-acute-upper-gastrointestinal-bleeding-in-hexagenerians-or-older-60-years-versus-younger-60-years-patients-clinico-endoscopic-profile-and-outcome","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:24:38Z","timestamp":1707506678000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/51886-acute-upper-gastrointestinal-bleeding-in-hexagenerians-or-older-60-years-versus-younger-60-years-patients-clinico-endoscopic-profile-and-outcome"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,23]]},"references-count":24,"URL":"https:\/\/doi.org\/10.7759\/cureus.13521","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2,23]]}}}