{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T00:17:38Z","timestamp":1707524258006},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,22]]},"DOI":"10.7759\/cureus.16554","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T10:47:31Z","timestamp":1626950851000},"source":"Crossref","is-referenced-by-count":4,"title":["A Retrospective Observational Study: Is Absolute Lymphocyte Count a Prognostic Marker in COVID-19?"],"prefix":"10.7759","author":[{"given":"Mansoor","family":"Zafar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Shahbaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mangala","family":"Karkhanis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abdelbagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Opeyemi  A","family":"Makanjuola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bipin","family":"Pun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ratan S","family":"Randhawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederic","family":"Cuison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Safarova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oluwamayowa","family":"Ojofeitimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamal","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariya","family":"Farooq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem","family":"Eldebri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saba","family":"Alam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucinda","family":"Barry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alisha","family":"Khanna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karuna","family":"Subba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amr","family":"Elyasaky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hesam A","family":"Nooredinvand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manivannan","family":"Periasamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bolurin A","family":"Adekunle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Maryam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao","family":"Khuu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Hegner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Esteves Morete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirej","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gjulio","family":"Ciroi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ubaid Ur","family":"Rehman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jabeen","family":"Hsiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maaryah J","family":"Zafar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadiyah","family":"Zafar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca A","family":"Lazau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najam-us-Saher","family":"Rizvi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Moran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A","family":"O'Neill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktoriya","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Berliti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Nakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tila","family":"Muhammad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osei","family":"Kankam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Whitehead","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellie M","family":"Giddings","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Merritt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umesh","family":"Dashora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30079-5","article-title":"Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study","volume":"8","author":"Yang X","year":"2020","unstructured":"Yang X, Yu Y, Xu J, et al.. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020, 8:475-481. 10.1016\/S2213-2600(20)30079-5","journal-title":"Lancet Respir Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032","article-title":"Clinical characteristics of coronavirus disease 2019 in China","volume":"382","author":"Guan WJ","year":"2020","unstructured":"Guan WJ, Ni ZY, Hu Y, et al.. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020, 382:1708-1720. 10.1056\/NEJMoa2002032","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.13288","article-title":"Absolute lymphocyte count is a prognostic marker in Covid-19: a retrospective cohort review","volume":"42","author":"Wagner J","year":"2020","unstructured":"Wagner J, DuPont A, Larson S, Cash B, Farooq A. Absolute lymphocyte count is a prognostic marker in Covid-19: a retrospective cohort review. Int J Lab Hematol. 2020, 42:761-765. 10.1111\/ijlh.13288","journal-title":"Int J Lab Hematol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s40560-020-00453-4","article-title":"Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis","volume":"8","author":"Huang I","year":"2020","unstructured":"Huang I, Pranata R. Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis. J Intensive Care. 2020, 8:36. 10.1186\/s40560-020-00453-4","journal-title":"J Intensive Care"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2020.102763","article-title":"Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients","volume":"55","author":"Liu J","year":"2020","unstructured":"Liu J, Li S, Liu J, et al.. Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients. EBioMedicine. 2020, 55:102763. 10.1016\/j.ebiom.2020.102763","journal-title":"EBioMedicine"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2015897","article-title":"False negative tests for SARS-CoV-2 infection - challenges and implications","volume":"383","author":"Woloshin S","year":"2020","unstructured":"Woloshin S, Patel N, Kesselheim AS. False negative tests for SARS-CoV-2 infection - challenges and implications. N Engl J Med. 2020, 383:e38. 10.1056\/NEJMp2015897","journal-title":"N Engl J Med"},{"key":"ref7","unstructured":"Guidance and Standard Operating Procedure COVID-19 Virus Testing in NHS Laboratories. (2020). https.\/\/www.rcpath.org\/uploads\/assets\/90111431-8aca-4614-b06633d07e2a3dd9\/Guidance-and-SOP-COVID-19-Testing-NHS-Labor...."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i1981","article-title":"Sparse data bias: a problem hiding in plain sight","volume":"352","author":"Greenland S","year":"2016","unstructured":"Greenland S, Mansournia MA, Altman DG. Sparse data bias: a problem hiding in plain sight. BMJ. 2016, 352:i1981. 10.1136\/bmj.i1981","journal-title":"BMJ"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2002.tb02943.x","article-title":"Viruses and diabetes","volume":"958","author":"Jaeckel E","year":"2002","unstructured":"Jaeckel E, Manns M, Von Herrath M. Viruses and diabetes. Ann N Y Acad Sci. 2002, 958:7-25. 10.1111\/j.1749-6632.2002.tb02943.x","journal-title":"Ann N Y Acad Sci"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.04.086","article-title":"Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a systemic review and meta-analysis","volume":"96","author":"Zhao Q","year":"2020","unstructured":"Zhao Q, Meng M, Kumar R, et al.. Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a systemic review and meta-analysis. Int J Infect Dis. 2020, 96:131-135. 10.1016\/j.ijid.2020.04.086","journal-title":"Int J Infect Dis"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-020-02374-0","article-title":"Neutrophil-to-lymphocyte ratio predicts critical illness patients with 2019 coronavirus disease in the early stage","volume":"18","author":"Liu J","year":"2020","unstructured":"Liu J, Liu Y, Xiang P, et al.. Neutrophil-to-lymphocyte ratio predicts critical illness patients with 2019 coronavirus disease in the early stage. J Transl Med. 2020, 18:206. 10.1186\/s12967-020-02374-0","journal-title":"J Transl Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2020.04.018","article-title":"Laboratory data analysis of novel coronavirus (COVID-19) screening in 2510 patients","volume":"507","author":"Yun H","year":"2020","unstructured":"Yun H, Sun Z, Wu J, Tang A, Hu M, Xiang Z. Laboratory data analysis of novel coronavirus (COVID-19) screening in 2510 patients. Clin Chim Acta. 2020, 507:94-97. 10.1016\/j.cca.2020.04.018","journal-title":"Clin Chim Acta"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-05991-x","article-title":"Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China","volume":"46","author":"Ruan Q","year":"2020","unstructured":"Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive Care Med. 2020, 46:846-848. 10.1007\/s00134-020-05991-x","journal-title":"Intensive Care Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1172\/JCI64096","article-title":"Causes, consequences, and reversal of immune system aging","volume":"123","author":"Montecino-Rodriguez E","year":"2013","unstructured":"Montecino-Rodriguez E, Berent-Maoz B, Dorshkind K. Causes, consequences, and reversal of immune system aging. J Clin Invest. 2013, 123:958-965. 10.1172\/JCI64096","journal-title":"J Clin Invest"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/ni1033","article-title":"Age-related changes in lymphocyte development and function","volume":"5","author":"Linton PJ","year":"2004","unstructured":"Linton PJ, Dorshkind K. Age-related changes in lymphocyte development and function. Nat Immunol. 2004, 5:133-139. 10.1038\/ni1033","journal-title":"Nat Immunol"},{"key":"ref16","unstructured":"Can HbA1c levels be used as an independent marker of mortality and morbidity risk in patients with COVID19 positive swabs? - a retrospective observational study. (2021). Accessed. June 24, 2021: https:\/\/www.utmj.org\/index.php\/UTMJ\/article\/view\/1494."},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.15490","article-title":"COVID-19 vaccination-induced rash: does the choice of vaccine matter?","volume":"13","author":"Zafar M","year":"2021","unstructured":"Zafar M, Ewnetu B, Ahmed S, Iqbal U, Whitehead M. COVID-19 vaccination-induced rash: does the choice of vaccine matter?. Cureus. 2021, 13:e15490. 10.7759\/cureus.15490","journal-title":"Cureus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/61072-a-retrospective-observational-study-is-absolute-lymphocyte-count-a-prognostic-marker-in-covid-19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:27:23Z","timestamp":1707506843000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/61072-a-retrospective-observational-study-is-absolute-lymphocyte-count-a-prognostic-marker-in-covid-19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,22]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.16554","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7,22]]}}}