{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T05:52:51Z","timestamp":1787896371825,"version":"build-2784847793"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,19]]},"DOI":"10.7759\/cureus.19750","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T17:32:02Z","timestamp":1637343122000},"source":"Crossref","is-referenced-by-count":1,"title":["Urologic Manifestations and Hydronephrosis as Initial Presentation of Erdheim-Chester Disease: A Rare Form of Non-Langerhans Histiocytosis"],"prefix":"10.7759","author":[{"given":"Skyler E","family":"Burke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akriti","family":"Chaudhry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin A","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle C","family":"Schuppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheddi","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane M","family":"Pearce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Mroch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01942684","article-title":"\u00dcber lipoidgranulomatose","volume":"279","author":"Chester W","year":"1930","unstructured":"Chester W. \u00dcber lipoidgranulomatose. Virchows Arch Pathol Anat. 1930, 279:561-602. 10.1007\/BF01942684","journal-title":"Virchows Arch Pathol Anat"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202542","article-title":"The multifaceted clinical presentations and manifestations of Erdheim-Chester disease: comprehensive review of the literature and of 10 new cases","volume":"72","author":"Cavalli G","year":"2013","unstructured":"Cavalli G, Guglielmi B, Berti A, Campochiaro C, Sabbadini MG, Dagna L. The multifaceted clinical presentations and manifestations of Erdheim-Chester disease: comprehensive review of the literature and of 10 new cases. Ann Rheum Dis. 2013, 72:1691-5. 10.1136\/annrheumdis-2012-202542","journal-title":"Ann Rheum Dis"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/3954165","article-title":"Kidney transplantation for Erdheim-Chester disease","volume":"2020","author":"Yoo J","year":"2020","unstructured":"Yoo J, Gunsteen C, Patel S, et al.. Kidney transplantation for Erdheim-Chester disease. Case Rep Transplant. 2020, 2020:3954165. 10.1155\/2020\/3954165","journal-title":"Case Rep Transplant"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1053\/crad.2001.0681","article-title":"Erdheim-Chester disease","volume":"56","author":"Murray D","year":"2001","unstructured":"Murray D, Marshall M, England E, Mander J, Chakera TM. Erdheim-Chester disease. Clin Radiol. 2001, 56:481-4. 10.1053\/crad.2001.0681","journal-title":"Clin Radiol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-06-294108","article-title":"CNS involvement and treatment with interferon-\u03b1 are independent prognostic factors in Erdheim-Chester disease: a multicenter survival analysis of 53 patients","volume":"117","author":"Arnaud L","year":"2011","unstructured":"Arnaud L, Hervier B, N\u00e9el A, et al.. CNS involvement and treatment with interferon-\u03b1 are independent prognostic factors in Erdheim-Chester disease: a multicenter survival analysis of 53 patients. Blood. 2011, 117:2778-82. 10.1182\/blood-2010-06-294108","journal-title":"Blood"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-12-757823","article-title":"Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults","volume":"130","author":"Milne P","year":"2017","unstructured":"Milne P, Bigley V, Bacon CM, et al.. Hematopoietic origin of Langerhans cell histiocytosis and Erdheim-Chester disease in adults. Blood. 2017, 130:167-75. 10.1182\/blood-2016-12-757823","journal-title":"Blood"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-12-757377","article-title":"Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem\/progenitor cells","volume":"130","author":"Durham BH","year":"2017","unstructured":"Durham BH, Roos-Weil D, Baillou C, et al.. Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem\/progenitor cells. Blood. 2017, 130:176-80. 10.1182\/blood-2016-12-757377","journal-title":"Blood"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-04-279083","article-title":"Recurrent BRAF mutations in Langerhans cell histiocytosis","volume":"116","author":"Badalian-Very G","year":"2010","unstructured":"Badalian-Very G, Vergilio JA, Degar BA, et al.. Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood. 2010, 116:1919-23. 10.1182\/blood-2010-04-279083","journal-title":"Blood"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-03-561381","article-title":"Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease","volume":"124","author":"Diamond EL","year":"2014","unstructured":"Diamond EL, Dagna L, Hyman DM, et al.. Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease. Blood. 2014, 124:483-92. 10.1182\/blood-2014-03-561381","journal-title":"Blood"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-10-313510","article-title":"Systemic perturbation of cytokine and chemokine networks in Erdheim-Chester disease: a single-center series of 37 patients","volume":"117","author":"Arnaud L","year":"2011","unstructured":"Arnaud L, Gorochov G, Charlotte F, et al.. Systemic perturbation of cytokine and chemokine networks in Erdheim-Chester disease: a single-center series of 37 patients. Blood. 2011, 117:2783-90. 10.1182\/blood-2010-10-313510","journal-title":"Blood"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2013.02.011","article-title":"Erdheim-Chester disease","volume":"39","author":"Haroche J","year":"2013","unstructured":"Haroche J, Arnaud L, Cohen-Aubart F, Hervier B, Charlotte F, Emile JF, Amoura Z. Erdheim-Chester disease. Rheum Dis Clin North Am. 2013, 39:299-311. 10.1016\/j.rdc.2013.02.011","journal-title":"Rheum Dis Clin North Am"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.10.023","article-title":"Urologic manifestations of Erdheim-Chester disease","volume":"84","author":"Yelfimov DA","year":"2014","unstructured":"Yelfimov DA, Lightner DJ, Tollefson MK. Urologic manifestations of Erdheim-Chester disease. Urology. 2014, 84:218-21. 10.1016\/j.urology.2013.10.023","journal-title":"Urology"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2707","article-title":"Erdheim-Chester disease of the central nervous system: new manifestations of a rare disease","volume":"32","author":"Sedrak P","year":"2011","unstructured":"Sedrak P, Ketonen L, Hou P, Guha-Thakurta N, Williams MD, Kurzrock R, Debnam JM. Erdheim-Chester disease of the central nervous system: new manifestations of a rare disease. AJNR Am J Neuroradiol. 2011, 32:2126-31. 10.3174\/ajnr.A2707","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref14","article-title":"\"Coated aorta\": a new sign of Erdheim-Chester disease","volume":"27","author":"Serratrice J","year":"2000","unstructured":"Serratrice J, Granel B, De Roux C, et al.. \"Coated aorta\": a new sign of Erdheim-Chester disease. J Rheumatol. 2000, 27:1550-3.","journal-title":"J Rheumatol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25055","article-title":"Phenotypes and survival in Erdheim-Chester disease: results from a 165-patient cohort","volume":"93","author":"Cohen-Aubart F","year":"2018","unstructured":"Cohen-Aubart F, Emile JF, Carrat F, et al.. Phenotypes and survival in Erdheim-Chester disease: results from a 165-patient cohort. Am J Hematol. 2018, 93:E114-7. 10.1002\/ajh.25055","journal-title":"Am J Hematol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2018.190728","article-title":"Prognostic factors of Erdheim-Chester disease: a nationwide survey in Japan","volume":"103","author":"Toya T","year":"2018","unstructured":"Toya T, Ogura M, Toyama K, et al.. Prognostic factors of Erdheim-Chester disease: a nationwide survey in Japan. Haematologica. 2018, 103:1815-24. 10.3324\/haematol.2018.190728","journal-title":"Haematologica"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1182\/hematology.2020000159","article-title":"Histiocytic disorders: insights into novel biology and implications for therapy of Langerhans cell histiocytosis and Erdheim-Chester disease","volume":"2020","author":"McClain K","year":"2020","unstructured":"McClain K. Histiocytic disorders: insights into novel biology and implications for therapy of Langerhans cell histiocytosis and Erdheim-Chester disease. Hematology Am Soc Hematol Educ Program. 2020, 2020:395-9. 10.1182\/hematology.2020000159","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.04.057","article-title":"Erdheim-Chester disease with cardiac involvement successfully treated with anakinra","volume":"167","author":"Killu AM","year":"2013","unstructured":"Killu AM, Liang JJ, Jaffe AS. Erdheim-Chester disease with cardiac involvement successfully treated with anakinra. Int J Cardiol. 2013, 167:e115-7. 10.1016\/j.ijcard.2013.04.057","journal-title":"Int J Cardiol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-07-446286","article-title":"Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation","volume":"121","author":"Haroche J","year":"2013","unstructured":"Haroche J, Cohen-Aubart F, Emile JF, et al.. Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation. Blood. 2013, 121:1495-500. 10.1182\/blood-2012-07-446286","journal-title":"Blood"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1012-y","article-title":"Efficacy of MEK inhibition in patients with histiocytic neoplasms","volume":"567","author":"Diamond EL","year":"2019","unstructured":"Diamond EL, Durham BH, Ulaner GA, et al.. Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019, 567:521-4. 10.1038\/s41586-019-1012-y","journal-title":"Nature"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019003507","article-title":"Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era","volume":"135","author":"Goyal G","year":"2020","unstructured":"Goyal G, Heaney ML, Collin M, et al.. Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era. Blood. 2020, 135:1929-45. 10.1182\/blood.2019003507","journal-title":"Blood"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/73388-urologic-manifestations-and-hydronephrosis-as-initial-presentation-of-erdheim-chester-disease-a-rare-form-of-non-langerhans-histiocytosis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:30:41Z","timestamp":1707507041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/73388-urologic-manifestations-and-hydronephrosis-as-initial-presentation-of-erdheim-chester-disease-a-rare-form-of-non-langerhans-histiocytosis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,19]]},"references-count":21,"URL":"https:\/\/doi.org\/10.7759\/cureus.19750","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11,19]]}}}