{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T05:17:29Z","timestamp":1722230249954},"reference-count":33,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,2]]},"DOI":"10.7759\/cureus.21832","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T12:23:16Z","timestamp":1643804596000},"source":"Crossref","is-referenced-by-count":1,"title":["Immunotherapy Effectiveness in Treating Peanut Hypersensitivity: A Systemic Review"],"prefix":"10.7759","author":[{"given":"Rahaf","family":"Alghamdi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania","family":"Alshaier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aljawharah","family":"Alotaibi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amani","family":"Almutairi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghadeer","family":"Alotaibi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aisha","family":"Faqeeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assail","family":"Almalki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hind","family":"AbdulMajed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.12.622","article-title":"Further fatalities caused by anaphylactic reactions to food, 2001-2006","volume":"119","author":"Bock SA","year":"2007","unstructured":"Bock SA, Mu\u00f1oz-Furlong A, Sampson HA. Further fatalities caused by anaphylactic reactions to food, 2001-2006. J Allergy Clin Immunol. 2007, 119:1016-8. 10.1016\/j.jaci.2006.12.622","journal-title":"J Allergy Clin Immunol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.05.013","article-title":"Food allergy: a practice parameter update-2014","volume":"134","author":"Sampson HA","year":"2014","unstructured":"Sampson HA, Aceves S, Bock SA, et al.. Food allergy: a practice parameter update-2014. J Allergy Clin Immunol. 2014, 134:1016-25.e43. 10.1016\/j.jaci.2014.05.013","journal-title":"J Allergy Clin Immunol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414850","article-title":"Randomized trial of peanut consumption in infants at risk for peanut allergy","volume":"372","author":"Du Toit G","year":"2015","unstructured":"Du Toit G, Roberts G, Sayre PH, et al.. Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015, 372:803-13. 10.1056\/NEJMoa1414850","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/all.12429","article-title":"EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy","volume":"69","author":"Muraro A","year":"2014","unstructured":"Muraro A, Werfel T, Hoffmann-Sommergruber K, et al.. EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy. Allergy. 2014, 69:1008-25. 10.1111\/all.12429","journal-title":"Allergy"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.112129","article-title":"The natural history of peanut allergy","volume":"107","author":"Skolnick HS","year":"2001","unstructured":"Skolnick HS, Conover-Walker MK, Koerner CB, Sampson HA, Burks W, Wood RA. The natural history of peanut allergy. J Allergy Clin Immunol. 2001, 107:367-74. 10.1067\/mai.2001.112129","journal-title":"J Allergy Clin Immunol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.01.002","article-title":"Natural history of peanut allergy and predictors of resolution in the first 4 years of life: a population-based assessment","volume":"135","author":"Peters RL","year":"2015","unstructured":"Peters RL, Allen KJ, Dharmage SC, et al.. Natural history of peanut allergy and predictors of resolution in the first 4 years of life: a population-based assessment. J Allergy Clin Immunol. 2015, 135:1257-66.e1-2. 10.1016\/j.jaci.2015.01.002","journal-title":"J Allergy Clin Immunol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.05.032","article-title":"Audit of manufactured products: use of allergen advisory labels and identification of labeling ambiguities","volume":"124","author":"Pieretti MM","year":"2009","unstructured":"Pieretti MM, Chung D, Pacenza R, Slotkin T, Sicherer SH. Audit of manufactured products: use of allergen advisory labels and identification of labeling ambiguities. J Allergy Clin Immunol. 2009, 124:337-41. 10.1016\/j.jaci.2009.05.032","journal-title":"J Allergy Clin Immunol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.1.e6","article-title":"Clinical features of acute allergic reactions to peanut and tree nuts in children","volume":"102","author":"Sicherer SH","year":"1998","unstructured":"Sicherer SH, Burks AW, Sampson HA. Clinical features of acute allergic reactions to peanut and tree nuts in children. Pediatrics. 1998, 102:e6. 10.1542\/peds.102.1.e6","journal-title":"Pediatrics"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02121.x","article-title":"Health-related quality of life of food allergic patients: comparison with the general population and other diseases","volume":"65","author":"Flokstra-de Blok BM","year":"2010","unstructured":"Flokstra-de Blok BM, Dubois AE, Vlieg-Boerstra BJ, et al.. Health-related quality of life of food allergic patients: comparison with the general population and other diseases. Allergy. 2010, 65:238-44. 10.1111\/j.1398-9995.2009.02121.x","journal-title":"Allergy"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000486310","article-title":"Oral immunotherapy in Japanese children with anaphylactic peanut allergy","volume":"175","author":"Nagakura KI","year":"2018","unstructured":"Nagakura KI, Sato S, Yanagida N, Nishino M, Asaumi T, Ogura K, Ebisawa M. Oral immunotherapy in Japanese children with anaphylactic peanut allergy. Int Arch Allergy Immunol. 2018, 175:181-8. 10.1159\/000486310","journal-title":"Int Arch Allergy Immunol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(92)90080-l","article-title":"Treatment of peanut allergy with rush immunotherapy","volume":"90","author":"Oppenheimer JJ","year":"1992","unstructured":"Oppenheimer JJ, Nelson HS, Bock SA, Christensen F, Leung DY. Treatment of peanut allergy with rush immunotherapy. J Allergy Clin Immunol. 1992, 90:256-62. 10.1016\/0091-6749(92)90080-l","journal-title":"J Allergy Clin Immunol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30420-9","article-title":"Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety","volume":"393","author":"Chu D","year":"2019","unstructured":"Chu D, Wood R, French S, et al.. Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety. Lancet. 2019, 393:2222-32. 10.1016\/S0140-6736(19)30420-9","journal-title":"Lancet"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/all.13124","article-title":"Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis","volume":"72","author":"Nurmatov U","year":"2017","unstructured":"Nurmatov U, Dhami S, Arasi S, et al.. Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis. Allergy. 2017, 72:1133-47. 10.1111\/all.13124","journal-title":"Allergy"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins JP","year":"2011","unstructured":"Higgins JP, Altman DG, G\u00f8tzsche PC, et al.. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 2011, 343:d5928. 10.1136\/bmj.d5928","journal-title":"BMJ"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(97)80006-1","article-title":"Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract","volume":"99","author":"Nelson HS","year":"1997","unstructured":"Nelson HS, Lahr J, Rule R, et al.. Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract. J Allergy Clin Immunol. 1997, 99:744-51. 10.1016\/S0091-6749(97)80006-1","journal-title":"J Allergy Clin Immunol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.12.1111","article-title":"A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response","volume":"127","author":"Varshney P","year":"2011","unstructured":"Varshney P, Jones SM, Scurlock AM, et al.. A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response. J Allergy Clin Immunol. 2011, 127:654-60. 10.1016\/j.jaci.2010.12.1111","journal-title":"J Allergy Clin Immunol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62301-6","article-title":"Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial","volume":"383","author":"Anagnostou K","year":"2014","unstructured":"Anagnostou K, Islam S, King Y, et al.. Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial. Lancet. 2014, 383:1297-304. 10.1016\/S0140-6736(13)62301-6","journal-title":"Lancet"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13668","article-title":"Double-blind placebo-controlled challenge showed that peanut oral immunotherapy was effective for severe allergy without negative effects on\u00a0airway inflammation","volume":"106","author":"Kukkonen AK","year":"2017","unstructured":"Kukkonen AK, Uotila R, Malmberg LP, Pelkonen AS, M\u00e4kel\u00e4 MJ. Double-blind placebo-controlled challenge showed that peanut oral immunotherapy was effective for severe allergy without negative effects on\u00a0airway inflammation. Acta Paediatr. 2017, 106:274-81. 10.1111\/apa.13668","journal-title":"Acta Paediatr"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1812856","article-title":"AR101 oral immunotherapy for peanut allergy","volume":"379","author":"Vickery BP","year":"2018","unstructured":"Vickery BP, Vereda A, Casale TB, et al.. AR101 oral immunotherapy for peanut allergy. N Engl J Med. 2018, 379:1991-2001. 10.1056\/NEJMoa1812856","journal-title":"N Engl J Med"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31793-3","article-title":"Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study","volume":"394","author":"Chinthrajah RS","year":"2019","unstructured":"Chinthrajah RS, Purington N, Andorf S, et al.. Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study. Lancet. 2019, 394:1437-49. 10.1016\/S0140-6736(19)31793-3","journal-title":"Lancet"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(20)30234-0","article-title":"Efficacy and safety of oral immunotherapy with AR101 in European children with a peanut allergy (ARTEMIS): a multicentre, double-blind, randomised, placebo-controlled phase 3 trial","volume":"4","author":"Hourihane JO","year":"2020","unstructured":"Hourihane JO, Beyer K, Abbas A, et al.. Efficacy and safety of oral immunotherapy with AR101 in European children with a peanut allergy (ARTEMIS): a multicentre, double-blind, randomised, placebo-controlled phase 3 trial. Lancet Child Adolesc Health. 2020, 4:728-39. 10.1016\/S2352-4642(20)30234-0","journal-title":"Lancet Child Adolesc Health"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12243","article-title":"Monitoring Ara h 1, 2 and 3-sIgE and sIgG4 antibodies in peanut allergic children receiving oral rush immunotherapy","volume":"25","author":"Nozawa A","year":"2014","unstructured":"Nozawa A, Okamoto Y, Mov\u00e9rare R, Borres MP, Kurihara K. Monitoring Ara h 1, 2 and 3-sIgE and sIgG4 antibodies in peanut allergic children receiving oral rush immunotherapy. Pediatr Allergy Immunol. 2014, 25:323-8. 10.1111\/pai.12243","journal-title":"Pediatr Allergy Immunol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.01982.x","article-title":"Successful oral tolerance induction in severe peanut allergy","volume":"64","author":"Clark AT","year":"2009","unstructured":"Clark AT, Islam S, King Y, Deighton J, Anagnostou K, Ewan PW. Successful oral tolerance induction in severe peanut allergy. Allergy. 2009, 64:1218-20. 10.1111\/j.1398-9995.2009.01982.x","journal-title":"Allergy"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.05.022","article-title":"Clinical efficacy and immune regulation with peanut oral immunotherapy","volume":"124","author":"Jones SM","year":"2009","unstructured":"Jones SM, Pons L, Roberts JL, et al.. Clinical efficacy and immune regulation with peanut oral immunotherapy. J Allergy Clin Immunol. 2009, 124:292-300, 300.e1-97. 10.1016\/j.jaci.2009.05.022","journal-title":"J Allergy Clin Immunol"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.05.027","article-title":"Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective","volume":"139","author":"Vickery BP","year":"2017","unstructured":"Vickery BP, Berglund JP, Burk CM, et al.. Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective. J Allergy Clin Immunol. 2017, 139:173-181.e8. 10.1016\/j.jaci.2016.05.027","journal-title":"J Allergy Clin Immunol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.11.005","article-title":"A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy","volume":"135","author":"Narisety SD","year":"2015","unstructured":"Narisety SD, Frischmeyer-Guerrerio PA, Keet CA, Gorelik M, Schroeder J, Hamilton RG, Wood RA. A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy. J Allergy Clin Immunol. 2015, 135:1275-82.e1-6. 10.1016\/j.jaci.2014.11.005","journal-title":"J Allergy Clin Immunol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.12.1083","article-title":"Sublingual immunotherapy for peanut allergy: clinical and immunologic evidence of desensitization","volume":"127","author":"Kim EH","year":"2011","unstructured":"Kim EH, Bird JA, Kulis M, et al.. Sublingual immunotherapy for peanut allergy: clinical and immunologic evidence of desensitization. J Allergy Clin Immunol. 2011, 127:640-6.e1. 10.1016\/j.jaci.2010.12.1083","journal-title":"J Allergy Clin Immunol"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.12.1917","article-title":"Sublingual immunotherapy for peanut allergy: long-term follow-up of a randomized multicenter trial","volume":"135","author":"Burks AW","year":"2015","unstructured":"Burks AW, Wood RA, Jones SM, et al.. Sublingual immunotherapy for peanut allergy: long-term follow-up of a randomized multicenter trial. J Allergy Clin Immunol. 2015, 135:1240-8.e1-3. 10.1016\/j.jaci.2014.12.1917","journal-title":"J Allergy Clin Immunol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.11.007","article-title":"Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy","volume":"133","author":"Vickery BP","year":"2014","unstructured":"Vickery BP, Scurlock AM, Kulis M, et al.. Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol. 2014, 133:468-75. 10.1016\/j.jaci.2013.11.007","journal-title":"J Allergy Clin Immunol"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.16591","article-title":"Effect of varying doses of epicutaneous immunotherapy vs placebo on reaction to peanut protein exposure among patients with peanut sensitivity: a randomized clinical trial","volume":"318","author":"Sampson HA","year":"2017","unstructured":"Sampson HA, Shreffler WG, Yang WH, et al.. Effect of varying doses of epicutaneous immunotherapy vs placebo on reaction to peanut protein exposure among patients with peanut sensitivity: a randomized clinical trial. JAMA. 2017, 318:1798-809. 10.1001\/jama.2017.16591","journal-title":"JAMA"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.08.017","article-title":"Epicutaneous immunotherapy for the treatment of peanut allergy in children and young adults","volume":"139","author":"Jones SM","year":"2017","unstructured":"Jones SM, Sicherer SH, Burks AW, et al.. Epicutaneous immunotherapy for the treatment of peanut allergy in children and young adults. J Allergy Clin Immunol. 2017, 139:1242-1252.e9. 10.1016\/j.jaci.2016.08.017","journal-title":"J Allergy Clin Immunol"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2020.08.015","article-title":"Improvements in quality of life in children following epicutaneous immunotherapy (EPIT) for peanut allergy in the PEPITES and PEOPLE studies","volume":"9","author":"DunnGalvin A","year":"2021","unstructured":"DunnGalvin A, Fleischer DM, Campbell DE, O'B Hourihane J, Green TD, Sampson HA, Greenhawt M. Improvements in quality of life in children following epicutaneous immunotherapy (EPIT) for peanut allergy in the PEPITES and PEOPLE studies. J Allergy Clin Immunol Pract. 2021, 9:216-224.e1. 10.1016\/j.jaip.2020.08.015","journal-title":"J Allergy Clin Immunol Pract"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-56961-3","article-title":"Adverse events associated with peanut oral immunotherapy in children - a systematic review and meta-analysis","volume":"10","author":"Grzeskowiak LE","year":"2020","unstructured":"Grzeskowiak LE, Tao B, Knight E, Cohen-Woods S, Chataway T. Adverse events associated with peanut oral immunotherapy in children - a systematic review and meta-analysis. Sci Rep. 2020, 10:659. 10.1038\/s41598-019-56961-3","journal-title":"Sci Rep"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/73885-immunotherapy-effectiveness-in-treating-peanut-hypersensitivity-a-systemic-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:37:12Z","timestamp":1707507432000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/73885-immunotherapy-effectiveness-in-treating-peanut-hypersensitivity-a-systemic-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,2]]},"references-count":33,"URL":"https:\/\/doi.org\/10.7759\/cureus.21832","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2,2]]}}}