{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T05:11:45Z","timestamp":1793596305768,"version":"4.5.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,17]]},"DOI":"10.7759\/cureus.24220","type":"journal-article","created":{"date-parts":[[2022,4,17]],"date-time":"2022-04-17T20:11:45Z","timestamp":1650226305000},"source":"Crossref","is-referenced-by-count":9,"title":["Metformin-Associated Lactic Acidosis: A Case Report and Review"],"prefix":"10.7759","author":[{"given":"Shoaib","family":"Ashraf","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Upreti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunita","family":"Karki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabih","family":"Nasr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-4758.2011.00605.x","article-title":"Metformin intoxication requiring dialysis","volume":"15","author":"Nguyen HL","year":"2011","unstructured":"Nguyen HL, Concepcion L. Metformin intoxication requiring dialysis. Hemodial Int. 2011, 15:S68-71. 10.1111\/j.1542-4758.2011.00605.x","journal-title":"Hemodial Int"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199630050-00003","article-title":"Clinical pharmacokinetics of metformin","volume":"30","author":"Scheen AJ","year":"1996","unstructured":"Scheen AJ. Clinical pharmacokinetics of metformin. Clin Pharmacokinet. 1996, 30:359-71. 10.2165\/00003088-199630050-00003","journal-title":"Clin Pharmacokinet"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2006.03.004","article-title":"Metformin-associated lactic acidosis treated with continuous renal replacement therapy","volume":"28","author":"Alivanis P","year":"2006","unstructured":"Alivanis P, Giannikouris I, Paliuras C, Arvanitis A, Volanaki M, Zervos A. Metformin-associated lactic acidosis treated with continuous renal replacement therapy. Clin Ther. 2006, 28:396-400. 10.1016\/j.clinthera.2006.03.004","journal-title":"Clin Ther"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2015.10.014","article-title":"Metformin-associated lactic acidosis: current perspectives on causes and risk","volume":"65","author":"DeFronzo R","year":"2016","unstructured":"DeFronzo R, Fleming GA, Chen K, Bicsak TA. Metformin-associated lactic acidosis: current perspectives on causes and risk. Metabolism. 2016, 65:20-9. 10.1016\/j.metabol.2015.10.014","journal-title":"Metabolism"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.5527\/wjn.v5.i4.367","article-title":"Metformin associated lactic acidosis in Auckland City Hospital 2005 to 2009","volume":"5","author":"Haloob I","year":"2016","unstructured":"Haloob I, de Zoysa JR. Metformin associated lactic acidosis in Auckland City Hospital 2005 to 2009. World J Nephrol. 2016, 5:367-71. 10.5527\/wjn.v5.i4.367","journal-title":"World J Nephrol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s40800-018-0076-1","article-title":"Metformin-associated lactic acidosis: a case report","volume":"5","author":"Umeda T","year":"2018","unstructured":"Umeda T, Minami T, Bartolomei K, Summerhill E. Metformin-associated lactic acidosis: a case report. Drug Saf Case Rep. 2018, 5:8. 10.1007\/s40800-018-0076-1","journal-title":"Drug Saf Case Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1530\/EDM-17-0148","article-title":"Recurrent lactic acidosis and hypoglycemia with inadvertent metformin use: a case of look-alike pills","volume":"2018","author":"Jacob T","year":"2018","unstructured":"Jacob T, Garrick R, Goldberg MD. Recurrent lactic acidosis and hypoglycemia with inadvertent metformin use: a case of look-alike pills. Endocrinol Diabetes Metab Case Rep. 2018, 2018:10.1530\/EDM-17-0148","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-8-159","article-title":"Metformin-associated lactic acidosis presenting as an ischemic gut in a patient who then survived a cardiac arrest: a case report","volume":"8","author":"Ncomanzi D","year":"2014","unstructured":"Ncomanzi D, Sicat RM, Sundararajan K. Metformin-associated lactic acidosis presenting as an ischemic gut in a patient who then survived a cardiac arrest: a case report. J Med Case Rep. 2014, 8:159. 10.1186\/1752-1947-8-159","journal-title":"J Med Case Rep"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181a02490","article-title":"Metformin-associated lactic acidosis: a prognostic and therapeutic study","volume":"37","author":"Seidowsky A","year":"2009","unstructured":"Seidowsky A, Nseir S, Houdret N, Fourrier F. Metformin-associated lactic acidosis: a prognostic and therapeutic study. Crit Care Med. 2009, 37:2191-6. 10.1097\/CCM.0b013e3181a02490","journal-title":"Crit Care Med"},{"key":"ref10","article-title":"Metformin-associated lactic acidosis (MALA): clinical profile and outcomes in patients admitted to the intensive care unit","volume":"12","author":"Biradar V","year":"2010","unstructured":"Biradar V, Moran JL, Peake SL, Peter JV. Metformin-associated lactic acidosis (MALA): clinical profile and outcomes in patients admitted to the intensive care unit. Crit Care Resusc. 2010, 12:191-5.","journal-title":"Crit Care Resusc"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199920040-00006","article-title":"Lactic acidosis in metformin-treated patients. Prognostic value of arterial lactate levels and plasma metformin concentrations","volume":"20","author":"Lalau JD","year":"1999","unstructured":"Lalau JD, Race JM. Lactic acidosis in metformin-treated patients. Prognostic value of arterial lactate levels and plasma metformin concentrations. Drug Saf. 1999, 20:377-84. 10.2165\/00002018-199920040-00006","journal-title":"Drug Saf"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/65912-metformin-associated-lactic-acidosis-a-case-report-and-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:38:16Z","timestamp":1707507496000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/65912-metformin-associated-lactic-acidosis-a-case-report-and-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,17]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.24220","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4,17]]}}}