{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:25:19Z","timestamp":1759332319017},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,10]]},"DOI":"10.7759\/cureus.26715","type":"journal-article","created":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T14:24:47Z","timestamp":1657463087000},"source":"Crossref","is-referenced-by-count":7,"title":["Study of Arterial Blood Gas Analysis in Moderate-to-Severe COVID-19 Patients"],"prefix":"10.7759","author":[{"given":"Hiren","family":"Sanghani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumit","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijaysinh","family":"Parmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Features, evaluation, and treatment of coronavirus (COVID-19)","author":"Cascella M","year":"2022","unstructured":"Cascella M, Rajnik M, Aleem A, et al.. Features, evaluation, and treatment of coronavirus (COVID-19). StatPearls Publishing, Treasure Island, FL; 2022."},{"key":"ref2","unstructured":"Chinese Center for Disease Control and Prevention. (2022). Accessed. May 6, 2022: http:\/\/www.chinacdc.cn\/jkzt\/crb\/zl\/szkb_11803\/jszl_2275\/202001\/t20200121_211326.html."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030747","article-title":"Identification of a novel coronavirus in patients with severe acute respiratory syndrome","volume":"348","author":"Drosten C","year":"2003","unstructured":"Drosten C, G\u00fcnther S, Preiser W, et al.. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med. 2003, 348:1967-76. 10.1056\/NEJMoa030747","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038638","article-title":"Characterization of human coronavirus etiology in Chinese adults with acute upper respiratory tract infection by real-time RT-PCR assays","volume":"7","author":"Lu R","year":"2012","unstructured":"Lu R, Yu X, Wang W, et al.. Characterization of human coronavirus etiology in Chinese adults with acute upper respiratory tract infection by real-time RT-PCR assays. PLoS One. 2012, 7:e38638. 10.1371\/journal.pone.0038638","journal-title":"PLoS One"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/cc2912","article-title":"Clinical review: acid-base abnormalities in the intensive care unit -- part II","volume":"9","author":"Kaplan LJ","year":"2005","unstructured":"Kaplan LJ, Frangos S. Clinical review: acid-base abnormalities in the intensive care unit -- part II. Crit Care. 2005, 9:198-203. 10.1186\/cc2912","journal-title":"Crit Care"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30229-0","article-title":"Management of acute kidney injury in patients with COVID-19","volume":"8","author":"Ronco C","year":"2020","unstructured":"Ronco C, Reis T, Husain-Syed F. Management of acute kidney injury in patients with COVID-19. Lancet Respir Med. 2020, 8:738-42. 10.1016\/S2213-2600(20)30229-0","journal-title":"Lancet Respir Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2001017","article-title":"A novel coronavirus from patients with pneumonia in China, 2019","volume":"382","author":"Zhu N","year":"2020","unstructured":"Zhu N, Zhang D, Wang W, et al.. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020, 382:727-33. 10.1056\/NEJMoa2001017","journal-title":"N Engl J Med"},{"key":"ref8","article-title":"Blood gas analysis among covid-19 positive patients: a single centre, retrospective, observational study","volume":"15","author":"Mondal S","year":"2021","unstructured":"Mondal S, Das TK, Bhattacharya S, Banerjee S, Hazra D. Blood gas analysis among covid-19 positive patients: a single centre, retrospective, observational study. J Clin Diagn Res. 2021, 15:LC01-4.","journal-title":"J Clin Diagn Res"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30079-5","article-title":"Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study","volume":"8","author":"Yang X","year":"2020","unstructured":"Yang X, Yu Y, Xu J, et al.. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med. 2020, 8:475-81. 10.1016\/S2213-2600(20)30079-5","journal-title":"Lancet Respir Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2004500","article-title":"Covid-19 in critically ill patients in the Seattle region - case series","volume":"382","author":"Bhatraju PK","year":"2020","unstructured":"Bhatraju PK, Ghassemieh BJ, Nichols M, et al.. Covid-19 in critically ill patients in the Seattle region - case series. N Engl J Med. 2020, 382:2012-22. 10.1056\/NEJMoa2004500","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.5394","article-title":"Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy","volume":"323","author":"Grasselli G","year":"2020","unstructured":"Grasselli G, Zangrillo A, Zanella A, et al.. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA. 2020, 323:1574-81. 10.1001\/jama.2020.5394","journal-title":"JAMA"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.c110030","article-title":"Ventilatory failure, ventilator support, and ventilator weaning","volume":"2","author":"Tobin MJ","year":"2012","unstructured":"Tobin MJ, Laghi F, Jubran A. Ventilatory failure, ventilator support, and ventilator weaning. Compr Physiol. 2012, 2:2871-921. 10.1002\/cphy.c110030","journal-title":"Compr Physiol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.9734\/ajrid\/2021\/v6i330199","article-title":"Arterial blood gas analysis of critically ill corona virus disease 2019 patients","volume":"6","author":"Lakhani J","year":"2021","unstructured":"Lakhani J, Kapadia S, Pandya H, Gill R, Chordiya R, Muley A. Arterial blood gas analysis of critically ill corona virus disease 2019 patients. Asian J Res Infect Dis. 2021, 6:51-63. 10.9734\/ajrid\/2021\/v6i330199","journal-title":"Asian J Res Infect Dis"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1177\/0004563220972539","article-title":"Correlating arterial blood gas, acid-base and blood pressure abnormalities with outcomes in COVID-19 intensive care patients","volume":"58","author":"Bezuidenhout MC","year":"2021","unstructured":"Bezuidenhout MC, Wiese OJ, Moodley D, et al.. Correlating arterial blood gas, acid-base and blood pressure abnormalities with outcomes in COVID-19 intensive care patients. Ann Clin Biochem. 2021, 58:95-101. 10.1177\/0004563220972539","journal-title":"Ann Clin Biochem"},{"key":"ref15","article-title":"Arterial blood gas","author":"Castro D","year":"2022","unstructured":"Castro D, Patil SM, Keenaghan M. Arterial blood gas. StatPearls publishing, Treasure Island, FL; 2022."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-020-02377-1","article-title":"Does this patient have COVID-19? A practical guide for the internist","volume":"15","author":"Bertolino L","year":"2020","unstructured":"Bertolino L, Vitrone M, Durante-Mangoni E. Does this patient have COVID-19? A practical guide for the internist. Intern Emerg Med. 2020, 15:791-800. 10.1007\/s11739-020-02377-1","journal-title":"Intern Emerg Med"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-021-02855-1","article-title":"Acid base disorders in patients with COVID-19","volume":"54","author":"Alfano G","year":"2022","unstructured":"Alfano G, Fontana F, Mori G, et al.. Acid base disorders in patients with COVID-19. Int Urol Nephrol. 2022, 54:405-10. 10.1007\/s11255-021-02855-1","journal-title":"Int Urol Nephrol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/cc3987","article-title":"Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients","volume":"10","author":"Gunnerson KJ","year":"2006","unstructured":"Gunnerson KJ, Saul M, He S, Kellum JA. Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients. Crit Care. 2006, 10:R22. 10.1186\/cc3987","journal-title":"Crit Care"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-015-0984-8","article-title":"Pulse oximetry","volume":"19","author":"Jubran A","year":"2015","unstructured":"Jubran A. Pulse oximetry. Crit Care. 2015, 19:272. 10.1186\/s13054-015-0984-8","journal-title":"Crit Care"},{"key":"ref20","article-title":"Respiratory alkalosis","author":"Brinkman JE","year":"2022","unstructured":"Brinkman JE, Sharma S. Respiratory alkalosis. StatPearls Publishing, Treasure Island, FL; 2022."},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.564635","article-title":"Association between respiratory alkalosis and the prognosis of COVID-19 patients","volume":"8","author":"Wu C","year":"2021","unstructured":"Wu C, Wang G, Zhang Q, et al.. Association between respiratory alkalosis and the prognosis of COVID-19 patients. Front Med (Lausanne). 2021, 8:564635. 10.3389\/fmed.2021.564635","journal-title":"Front Med (Lausanne)"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1530\/EC-21-0265","article-title":"Electrolyte and acid-base imbalance in severe COVID-19","volume":"10","author":"Sj\u00f6str\u00f6m A","year":"2021","unstructured":"Sj\u00f6str\u00f6m A, Rysz S, Sj\u00f6str\u00f6m H, H\u00f6ybye C. Electrolyte and acid-base imbalance in severe COVID-19. Endocr Connect. 2021, 10:805-14. 10.1530\/EC-21-0265","journal-title":"Endocr Connect"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.08.005","article-title":"Metabolic acidosis as a possible cause of CKD: what should clinicians do?","volume":"64","author":"Kovesdy CP","year":"2014","unstructured":"Kovesdy CP. Metabolic acidosis as a possible cause of CKD: what should clinicians do?. Am J Kidney Dis. 2014, 64:481-3. 10.1053\/j.ajkd.2014.08.005","journal-title":"Am J Kidney Dis"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs609","article-title":"Serum bicarbonate and mortality in adults in NHANES III","volume":"28","author":"Raphael KL","year":"2013","unstructured":"Raphael KL, Zhang Y, Wei G, Greene T, Cheung AK, Beddhu S. Serum bicarbonate and mortality in adults in NHANES III. Nephrol Dial Transplant. 2013, 28:1207-13. 10.1093\/ndt\/gfs609","journal-title":"Nephrol Dial Transplant"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/s0749-0704(01)00012-4","article-title":"Metabolic acidosis in the intensive care unit","volume":"18","author":"Gauthier PM","year":"2002","unstructured":"Gauthier PM, Szerlip HM. Metabolic acidosis in the intensive care unit. Crit Care Clin. 2002, 18:289-308, vi. 10.1016\/s0749-0704(01)00012-4","journal-title":"Crit Care Clin"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1515\/jtim-2016-0036","article-title":"Metabolic acidosis status and mortality in patients on the end stage of renal disease","volume":"4","author":"Raikou VD Md PhD","year":"2016","unstructured":"Raikou VD Md PhD. Metabolic acidosis status and mortality in patients on the end stage of renal disease. J Transl Int Med. 2016, 4:170-7. 10.1515\/jtim-2016-0036","journal-title":"J Transl Int Med"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1186\/cc10487","article-title":"Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study","volume":"15","author":"Jung B","year":"2011","unstructured":"Jung B, Rimmele T, Le Goff C, et al.. Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study. Crit Care. 2011, 15:R238. 10.1186\/cc10487","journal-title":"Crit Care"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1972.48","article-title":"The effects of acid-base disturbances on cardiovascular and pulmonary function","volume":"1","author":"Mitchell JH","year":"1972","unstructured":"Mitchell JH, Wildenthal K, Johnson RL Jr. The effects of acid-base disturbances on cardiovascular and pulmonary function. Kidney Int. 1972, 1:375-89. 10.1038\/ki.1972.48","journal-title":"Kidney Int"},{"key":"ref29","doi-asserted-by":"crossref","DOI":"10.18203\/2349-3933.ijam20190086","article-title":"Acid based disorders in intensive care unit: a hospital-based study","volume":"6","author":"Rajendran B","year":"2019","unstructured":"Rajendran B, Mallampati SR, Jha SJ. Acid based disorders in intensive care unit: a hospital-based study. Int J Adv Med. 2019, 6:62-5.","journal-title":"Int J Adv Med"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.7196\/samj.2020.v110i11.15287","article-title":"Metabolic alkalosis in hospitalised COVID-19 patients: a window to the pathogenesis?","volume":"110","author":"Rood J","year":"2020","unstructured":"Rood J, Davids R, Le Roux A, et al.. Metabolic alkalosis in hospitalised COVID-19 patients: a window to the pathogenesis?. S Afr Med J. 2020, 110:13109. 10.7196\/samj.2020.v110i11.15287","journal-title":"S Afr Med J"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/97497-study-of-arterial-blood-gas-analysis-in-moderate-to-severe-covid-19-patients","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:39:04Z","timestamp":1707507544000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/97497-study-of-arterial-blood-gas-analysis-in-moderate-to-severe-covid-19-patients"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,10]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.26715","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7,10]]}}}