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J Biol Chem. 2004, 279:43838-46. 10.1074\/jbc.M403612200","journal-title":"J Biol Chem"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-008-9125-4","article-title":"The parkinsonism-hyperpyrexia syndrome","volume":"10","author":"Newman EJ","year":"2009","unstructured":"Newman EJ, Grosset DG, Kennedy PG. The parkinsonism-hyperpyrexia syndrome. Neurocrit Care. 2009, 10:136-40. 10.1007\/s12028-008-9125-4","journal-title":"Neurocrit Care"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.c140017","article-title":"Heat stroke","volume":"5","author":"Leon LR","year":"2015","unstructured":"Leon LR, Bouchama A. Heat stroke. 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StatPearls Publishing, Treasure Island, FL; 2021."},{"key":"ref130","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.9.6318","article-title":"Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4- and NF-kappaB-dependent mechanism","volume":"179","author":"Chase MA","year":"2007","unstructured":"Chase MA, Wheeler DS, Lierl KM, Hughes VS, Wong HR, Page K. Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4- and NF-kappaB-dependent mechanism. J Immunol. 2007, 179:6318-24. 10.4049\/jimmunol.179.9.6318","journal-title":"J Immunol"},{"key":"ref131","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0905523","article-title":"Releasing signals, secretory pathways, and immune function of endogenous extracellular heat shock protein 72","volume":"79","author":"Johnson JD","year":"2006","unstructured":"Johnson JD, Fleshner M. 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J Clin Endocrinol Metab. 2004, 89:1512-25. 10.1210\/jc.2002-021444","journal-title":"J Clin Endocrinol Metab"},{"key":"ref136","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.39367","article-title":"Procalcitonin: a promising tool or just another overhyped test?","volume":"17","author":"Paudel R","year":"2020","unstructured":"Paudel R, Dogra P, Montgomery-Yates AA, Coz Yataco A. Procalcitonin: a promising tool or just another overhyped test?. Int J Med Sci. 2020, 17:332-7. 10.7150\/ijms.39367","journal-title":"Int J Med Sci"},{"key":"ref137","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1993.tb07526.x","article-title":"Exertional heat stroke induced by amphetamine analogues. Does dantrolene have a place?","volume":"48","author":"Watson JD","year":"1993","unstructured":"Watson JD, Ferguson C, Hinds CJ, Skinner R, Coakley JH. Exertional heat stroke induced by amphetamine analogues. Does dantrolene have a place?. Anaesthesia. 1993, 48:1057-60. 10.1111\/j.1365-2044.1993.tb07526.x","journal-title":"Anaesthesia"},{"key":"ref138","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-16104-4","article-title":"The impact of food bioactives on health: in vitro and ex vivo models","author":"Verhoeckx K","year":"2015","unstructured":"Verhoeckx K, Cotter P, L\u00f3pez-Exp\u00f3sito I, et al.. The impact of food bioactives on health: in vitro and ex vivo models. Springer, Cham, Switzerland; 2015. 10.1007\/978-3-319-16104-4"},{"key":"ref139","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073571","article-title":"Eicosapentaenoic acid enhances heat stress-impaired intestinal epithelial barrier function in Caco-2 cells","volume":"8","author":"Xiao G","year":"2013","unstructured":"Xiao G, Tang L, Yuan F, et al.. Eicosapentaenoic acid enhances heat stress-impaired intestinal epithelial barrier function in Caco-2 cells. 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MedGenMed. 2004, 6:6.","journal-title":"MedGenMed"},{"key":"ref144","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-199112000-00015","article-title":"Methamphetamine-induced ischemic colitis","volume":"13","author":"Johnson TD","year":"1991","unstructured":"Johnson TD, Berenson MM. Methamphetamine-induced ischemic colitis. J Clin Gastroenterol. 1991, 13:687-9. 10.1097\/00004836-199112000-00015","journal-title":"J Clin Gastroenterol"},{"key":"ref145","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2009.139","article-title":"Methamphetamine colitis: a rare case of ischemic colitis in a young patient","volume":"144","author":"Holubar SD","year":"2009","unstructured":"Holubar SD, Hassinger JP, Dozois EJ, Masuoka HC. Methamphetamine colitis: a rare case of ischemic colitis in a young patient. 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