{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:03:00Z","timestamp":1760101380537},"reference-count":26,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,3]]},"DOI":"10.7759\/cureus.27659","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T04:17:25Z","timestamp":1659586645000},"source":"Crossref","is-referenced-by-count":3,"title":["Hemoglobin Drop and the Need for Transfusion in Primary Knee Arthroplasty"],"prefix":"10.7759","author":[{"given":"Fatema H","family":"Madan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebrahim","family":"Khamis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Aqeel","family":"Alhassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Alrashid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Rahma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1703856114","article-title":"Knee osteoarthritis has doubled in prevalence since the mid-20th century","volume":"114","author":"Wallace IJ","year":"2017","unstructured":"Wallace IJ, Worthington S, Felson DT, et al.. Knee osteoarthritis has doubled in prevalence since the mid-20th century. Proc Natl Acad Sci U S A. 2017, 114:9332-6. 10.1073\/pnas.1703856114","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.N.01141","article-title":"Prevalence of total hip and knee replacement in the United States","volume":"97","author":"Maradit Kremers H","year":"2015","unstructured":"Maradit Kremers H, Larson DR, Crowson CS, et al.. Prevalence of total hip and knee replacement in the United States. J Bone Joint Surg Am. 2015, 97:1386-97. 10.2106\/JBJS.N.01141","journal-title":"J Bone Joint Surg Am"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/2151459318804113","article-title":"Complications and readmissions after total knee replacement in octogenarians and nonagenarians","volume":"9","author":"Yohe N","year":"2018","unstructured":"Yohe N, Funk A, Ciminero M, Erez O, Saleh A. Complications and readmissions after total knee replacement in octogenarians and nonagenarians. Geriatr Orthop Surg Rehabil. 2018, 9:2151459318804113. 10.1177\/2151459318804113","journal-title":"Geriatr Orthop Surg Rehabil"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-019-1422-4","article-title":"The effects of tourniquet use on blood loss in primary total knee arthroplasty for patients with osteoarthritis: a meta-analysis","volume":"14","author":"Cai DF","year":"2019","unstructured":"Cai DF, Fan QH, Zhong HH, Peng S, Song H. The effects of tourniquet use on blood loss in primary total knee arthroplasty for patients with osteoarthritis: a meta-analysis. J Orthop Surg Res. 2019, 14:348. 10.1186\/s13018-019-1422-4","journal-title":"J Orthop Surg Res"},{"key":"ref5","article-title":"A retrospective analysis of hemostatic techniques in primary total knee arthroplasty: traditional electrocautery, bipolar sealer, and argon beam coagulation","volume":"45","author":"Rosenthal BD","year":"2016","unstructured":"Rosenthal BD, Haughom BD, Levine BR. A retrospective analysis of hemostatic techniques in primary total knee arthroplasty: traditional electrocautery, bipolar sealer, and argon beam coagulation. Am J Orthop (Belle Mead NJ). 2016, 45:E187-91.","journal-title":"Am J Orthop (Belle Mead NJ)"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-017-0550-y","article-title":"Optimal release timing of temporary drain clamping after total knee arthroplasty","volume":"12","author":"Jeon YS","year":"2017","unstructured":"Jeon YS, Park JS, Kim MK. Optimal release timing of temporary drain clamping after total knee arthroplasty. J Orthop Surg Res. 2017, 12:47. 10.1186\/s13018-017-0550-y","journal-title":"J Orthop Surg Res"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006763","article-title":"The efficacy and safety of epinephrine for postoperative bleeding in total joint arthroplasty: A PRISMA-compliant meta-analysis","volume":"96","author":"Teng Y","year":"2017","unstructured":"Teng Y, Ma J, Ma X, Wang Y, Lu B, Guo C. The efficacy and safety of epinephrine for postoperative bleeding in total joint arthroplasty: A PRISMA-compliant meta-analysis. Medicine (Baltimore). 2017, 96:e6763. 10.1097\/MD.0000000000006763","journal-title":"Medicine (Baltimore)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1590\/1413-785220182601149210","article-title":"Efficacy of tranexamic acid in reducing blood loss in total knee arthroplasty","volume":"26","author":"Sadigursky D","year":"2018","unstructured":"Sadigursky D, Araujo LM, Fernandes RJ. Efficacy of tranexamic acid in reducing blood loss in total knee arthroplasty. Acta Ortop Bras. 2018, 26:63-6. 10.1590\/1413-785220182601149210","journal-title":"Acta Ortop Bras"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.03.059","article-title":"Comparison of 3 routes of administration of tranexamic acid on primary unilateral total knee arthroplasty: a prospective, randomized, controlled study","volume":"32","author":"Yuan X","year":"2017","unstructured":"Yuan X, Li B, Wang Q, Zhang X. Comparison of 3 routes of administration of tranexamic acid on primary unilateral total knee arthroplasty: a prospective, randomized, controlled study. J Arthroplasty. 2017, 32:2738-43. 10.1016\/j.arth.2017.03.059","journal-title":"J Arthroplasty"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20160301-05","article-title":"Safety, efficacy, and cost-effectiveness of tranexamic acid in orthopedic surgery","volume":"39","author":"Lin ZX","year":"2016","unstructured":"Lin ZX, Woolf SK. Safety, efficacy, and cost-effectiveness of tranexamic acid in orthopedic surgery. Orthopedics. 2016, 39:119-30. 10.3928\/01477447-20160301-05","journal-title":"Orthopedics"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/2309499016684725","article-title":"The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty","volume":"25","author":"Cankaya D","year":"2017","unstructured":"Cankaya D, Dasar U, Satilmis AB, Basaran SH, Akkaya M, Bozkurt M. The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty. J Orthop Surg (Hong Kong). 2017, 25:2309499016684725. 10.1177\/2309499016684725","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-018-1038-0","article-title":"Blood loss of total knee arthroplasty in osteoarthritis: an analysis of influential factors","volume":"13","author":"Hu Y","year":"2018","unstructured":"Hu Y, Li Q, Wei BG, Zhang XS, Torsha TT, Xiao J, Shi ZJ. Blood loss of total knee arthroplasty in osteoarthritis: an analysis of influential factors. J Orthop Surg Res. 2018, 13:325. 10.1186\/s13018-018-1038-0","journal-title":"J Orthop Surg Res"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s10195-006-0118-9","article-title":"Closed suction drainage after orthopaedic surgery: evidence versus practice","volume":"7","author":"Tucci G","year":"2006","unstructured":"Tucci G, Amorese V, Romanini E. Closed suction drainage after orthopaedic surgery: evidence versus practice. Journal of Orthopaedics and Traumatology. 2006, 7:29-32. 10.1007\/s10195-006-0118-9","journal-title":"Journal of Orthopaedics and Traumatology"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-019-1329-0","article-title":"The incidence and risk factors for allogenic blood transfusion in total knee and hip arthroplasty","volume":"14","author":"Song K","year":"2019","unstructured":"Song K, Pan P, Yao Y, Jiang T, Jiang Q. The incidence and risk factors for allogenic blood transfusion in total knee and hip arthroplasty. J Orthop Surg Res. 2019, 14:273. 10.1186\/s13018-019-1329-0","journal-title":"J Orthop Surg Res"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00352-18","article-title":"Transfusion-transmitted infections: an update on product screening, diagnostic techniques, and the path ahead","volume":"56","author":"Dean CL","year":"2018","unstructured":"Dean CL, Wade J, Roback JD. Transfusion-transmitted infections: an update on product screening, diagnostic techniques, and the path ahead. J Clin Microbiol. 2018, 56:10.1128\/JCM.00352-18","journal-title":"J Clin Microbiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.33160\/yam.2018.03.013","article-title":"Analysis of acute transfusion reactions and their occurrence times","volume":"61","author":"Hatayama Y","year":"2018","unstructured":"Hatayama Y, Matsumoto S, Hamada E, Kojima N, Hara A, Hino N, Motokura T. Analysis of acute transfusion reactions and their occurrence times\r\n. Yonago Acta Med. 2018, 61:87-90. 10.33160\/yam.2018.03.013","journal-title":"Yonago Acta Med"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2011.10.008","article-title":"Predicting need for allogeneic transfusion after total knee arthroplasty","volume":"27","author":"Noticewala MS","year":"2012","unstructured":"Noticewala MS, Nyce JD, Wang W, Geller JA, Macaulay W. Predicting need for allogeneic transfusion after total knee arthroplasty. J Arthroplasty. 2012, 27:961-7. 10.1016\/j.arth.2011.10.008","journal-title":"J Arthroplasty"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20190225-05","article-title":"Preoperative hemoglobin predicts postoperative transfusion despite antifibrinolytics during total knee arthroplasty","volume":"42","author":"Ryan SP","year":"2019","unstructured":"Ryan SP, Klement MR, Green CL, Blizzard DJ, Wellman SS, Seyler TM. Preoperative hemoglobin predicts postoperative transfusion despite antifibrinolytics during total knee arthroplasty. Orthopedics. 2019, 42:103-9. 10.3928\/01477447-20190225-05","journal-title":"Orthopedics"},{"key":"ref19","unstructured":"Strong evidence supports not using a drain with total knee arthroplasty (TKA) because there is no difference in complications or outcomes. . (2014). Accessed. 17\/07\/2022: http:\/\/https: \/\/www.orthoguidelines.org\/go\/cpg\/detail.cfm?id=1317."},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.4081\/or.2020.8663","article-title":"Efficacy of postoperative drainage in total knee arthroplasty: review of the literature","volume":"12","author":"Basilico M","year":"2020","unstructured":"Basilico M, Vitiello R, Liuzza F, et al.. Efficacy of postoperative drainage in total knee arthroplasty: review of the literature. Orthop Rev (Pavia). 2020, 12:8663. 10.4081\/or.2020.8663","journal-title":"Orthop Rev (Pavia)"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2015.10.005","article-title":"Closed suction drainage is not necessary for total knee arthroplasty: a prospective study on simultaneous bilateral surgeries of a mean follow-up of 5.5 years","volume":"31","author":"Watanabe T","year":"2016","unstructured":"Watanabe T, Muneta T, Yagishita K, Hara K, Koga H, Sekiya I. Closed suction drainage is not necessary for total knee arthroplasty: a prospective study on simultaneous bilateral surgeries of a mean follow-up of 5.5 years. J Arthroplasty. 2016, 31:641-5. 10.1016\/j.arth.2015.10.005","journal-title":"J Arthroplasty"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2017.03.002","article-title":"Tourniquet and closed-suction drains in total knee arthroplasty. No beneficial effects on bleeding management and knee function at a higher cost","volume":"103","author":"Yin D","year":"2017","unstructured":"Yin D, Delisle J, Banica A, et al.. Tourniquet and closed-suction drains in total knee arthroplasty. No beneficial effects on bleeding management and knee function at a higher cost. Orthop Traumatol Surg Res. 2017, 103:583-9. 10.1016\/j.otsr.2017.03.002","journal-title":"Orthop Traumatol Surg Res"},{"key":"ref23","unstructured":"Strong evidence supports that, in patients with no known contraindications, treatment with tranexamic acid decreases postoperative blood loss and reduces the necessity of postoperative transfusions following total knee arthroplasty (TKA). (2014). Accessed. 17.07.2022: https:\/\/www.orthoguidelines.org\/go\/cpg\/detail.cfm?id=1304."},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.5792\/ksrr.2016.28.3.188","article-title":"Effect of tranexamic acid on blood loss and blood transfusion reduction after total knee arthroplasty","volume":"28","author":"Seol YJ","year":"2016","unstructured":"Seol YJ, Seon JK, Lee SH, Jin C, Prakash J, Park YJ, Song EK. Effect of tranexamic acid on blood loss and blood transfusion reduction after total knee arthroplasty. Knee Surg Relat Res. 2016, 28:188-93. 10.5792\/ksrr.2016.28.3.188","journal-title":"Knee Surg Relat Res"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2018.04.043","article-title":"The efficacy of tranexamic acid in total knee arthroplasty: a network meta-analysis","volume":"33","author":"Fillingham YA","year":"2018","unstructured":"Fillingham YA, Ramkumar DB, Jevsevar DS, et al.. The efficacy of tranexamic acid in total knee arthroplasty: a network meta-analysis. J Arthroplasty. 2018, 33:3090-3098.e1. 10.1016\/j.arth.2018.04.043","journal-title":"J Arthroplasty"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.5792\/ksrr.2016.28.3.201","article-title":"Effect of closed suction drain on blood loss and transfusion rates in simultaneous bilateral total knee arthroplasty: a prospective randomized study","volume":"28","author":"Jhurani A","year":"2016","unstructured":"Jhurani A, Shetty GM, Gupta V, Saxena P, Singh N. Effect of closed suction drain on blood loss and transfusion rates in simultaneous bilateral total knee arthroplasty: a prospective randomized study. Knee Surg Relat Res. 2016, 28:201-6. 10.5792\/ksrr.2016.28.3.201","journal-title":"Knee Surg Relat Res"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/107004-hemoglobin-drop-and-the-need-for-transfusion-in-primary-knee-arthroplasty","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:41:19Z","timestamp":1707507679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/107004-hemoglobin-drop-and-the-need-for-transfusion-in-primary-knee-arthroplasty"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,3]]},"references-count":26,"URL":"https:\/\/doi.org\/10.7759\/cureus.27659","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8,3]]}}}