{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T09:28:56Z","timestamp":1749720536370},"reference-count":25,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,17]]},"DOI":"10.7759\/cureus.29256","type":"journal-article","created":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T12:05:00Z","timestamp":1663416300000},"source":"Crossref","is-referenced-by-count":2,"title":["Contribution and Effectiveness of Laboratory Testing in the Diagnostic Assessment of Juvenile Ischemic Stroke and Transient Ischemic Attack"],"prefix":"10.7759","author":[{"given":"Francesco","family":"Janes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Giacomello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Blarasin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Fabris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Lorenzut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gian Luigi","family":"Gigli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Curcio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariarosaria","family":"Valente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2010.36","article-title":"Ischemic stroke in the elderly: an overview of evidence","volume":"6","author":"Chen RL","year":"2010","unstructured":"Chen RL, Balami JS, Esiri MM, Chen LK, Buchan AM. Ischemic stroke in the elderly: an overview of evidence. Nat Rev Neurol. 2010, 6:256-65. 10.1038\/nrneurol.2010.36","journal-title":"Nat Rev Neurol"},{"key":"ref2","unstructured":"SPREAD - Stroke Prevention and Educational Awareness Diffusion. Ictus cerebrale. linee guida italiane di prevenzione e trattamento VIII edizione. (2016). Accessed: July 8, 2022: http:\/\/www.iso-spread.it\/capitoli\/LINEE_GUIDA_SPREAD_8a_EDIZIONE.pdf."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.19.8.977","article-title":"Incidence of stroke in young adults in Florence, Italy","volume":"19","author":"Nencini P","year":"1988","unstructured":"Nencini P, Inzitari D, Baruffi MC, et al.. Incidence of stroke in young adults in Florence, Italy. Stroke. 1988, 19:977-81. 10.1161\/01.str.19.8.977","journal-title":"Stroke"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.32.1.52","article-title":"Stroke in young adults in the community-based L'Aquila registry: incidence and prognosis","volume":"32","author":"Marini C","year":"2001","unstructured":"Marini C, Totaro R, De Santis F, Ciancarelli I, Baldassarre M, Carolei A. Stroke in young adults in the community-based L'Aquila registry: incidence and prognosis. Stroke. 2001, 32:52-6. 10.1161\/01.str.32.1.52","journal-title":"Stroke"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.040543","article-title":"Ischaemic stroke in young adults: predictors of outcome and recurrence","volume":"76","author":"Nedeltchev K","year":"2005","unstructured":"Nedeltchev K, der Maur TA, Georgiadis D, et al.. Ischaemic stroke in young adults: predictors of outcome and recurrence. J Neurol Neurosurg Psychiatry. 2005, 76:191-5. 10.1136\/jnnp.2004.040543","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70251-9","article-title":"Aetiological diagnosis of ischaemic stroke in young adults","volume":"9","author":"Ferro Jos\u00e9 M","year":"2010","unstructured":"Ferro Jos\u00e9 M, Massaro AR, Mas JL. Aetiological diagnosis of ischaemic stroke in young adults. Lancet Neurol. 2010, 9:1085-96. 10.1016\/S1474-4422(10)70251-9","journal-title":"Lancet Neurol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4103\/0970-0218.80798","article-title":"A Study on Stroke and its Outcome in Young adults (15-45 Years) from coastal South India","volume":"36","author":"Kumar HH","year":"2011","unstructured":"Kumar HH, Kalra B, Goyal N. A Study on Stroke and its Outcome in Young adults (15-45 Years) from coastal South India. Indian J Community Med. 2011, 36:62-5. 10.4103\/0970-0218.80798","journal-title":"Indian J Community Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.113.000390","article-title":"Genetics of ischemic stroke in young adults","volume":"7","author":"Cheng YC","year":"2014","unstructured":"Cheng YC, Cole JW, Kittner SJ, Mitchell BD. Genetics of ischemic stroke in young adults. Circ Cardiovasc Genet. 2014, 7:383-92. 10.1161\/CIRCGENETICS.113.000390","journal-title":"Circ Cardiovasc Genet"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2015.08.004","article-title":"[Ischemic stroke in the young adult]","volume":"37","author":"Calvet D","year":"2016","unstructured":"Calvet D. [Ischemic stroke in the young adult]. Rev Med Interne. 2016, 37:19-24. 10.1016\/j.revmed.2015.08.004","journal-title":"Rev Med Interne"},{"key":"ref10","unstructured":"International Classification of Diseases,Ninth Revision, Clinical Modification (ICD-9-CM). (1997). Accessed. July 8, 2022: https:\/\/www.cdc.gov\/nchs\/icd\/icd9cm.htm#ftp."},{"key":"ref11","article-title":"WHO STEPS stroke manual : The WHO STEPwise Approach to Stroke Surveillance\/Noncommunicable Diseases and Mental Health, World Health Organization","author":"World Health Organization","year":"2006","unstructured":"World Health Organization. WHO STEPS stroke manual : The WHO STEPwise Approach to Stroke Surveillance\/Noncommunicable Diseases and Mental Health, World Health Organization. WHO, Geneva; 2006."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2019.03.021","article-title":"Identification of high-risk patent foramen ovale associated with cryptogenic stroke: development of a scoring system","volume":"32","author":"Nakayama R","year":"2019","unstructured":"Nakayama R, Takaya Y, Akagi T, et al.. Identification of high-risk patent foramen ovale associated with cryptogenic stroke: development of a scoring system. J Am Soc Echocardiogr. 2019, 32:811-6. 10.1016\/j.echo.2019.03.021","journal-title":"J Am Soc Echocardiogr"},{"key":"ref13","unstructured":"Nomenclatore tariffario FVG. (2019). Accessed. September 29, 2020: http:\/\/www.regione.fvg.it\/rafvg\/export\/sites\/default\/RAFVG\/salute-sociale\/sistema-sociale-sanitario\/FOGLIA51\/allegati...."},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12228","article-title":"Etiology of first-ever ischaemic stroke in European young adults: the 15 cities young stroke study","volume":"20","author":"Yesilot Barlas N","year":"2013","unstructured":"Yesilot Barlas N, Putaala J, Waje-Andreassen U, et al.. Etiology of first-ever ischaemic stroke in European young adults: the 15 cities young stroke study. Eur J Neurol. 2013, 20:1431-9. 10.1111\/ene.12228","journal-title":"Eur J Neurol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.117.016599","article-title":"Contribution of established stroke risk factors to the burden of stroke in young adults","volume":"48","author":"Aigner A","year":"2017","unstructured":"Aigner A, Grittner U, Rolfs A, Norrving B, Siegerink B, Busch MA. Contribution of established stroke risk factors to the burden of stroke in young adults. Stroke. 2017, 48:1744-51. 10.1161\/STROKEAHA.117.016599","journal-title":"Stroke"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2013.10.008","article-title":"Risk factor and etiology analysis of ischemic stroke in young adult patients","volume":"23","author":"Renna R","year":"2014","unstructured":"Renna R, Pilato F, Profice P, et al.. Risk factor and etiology analysis of ischemic stroke in young adult patients. J Stroke Cerebrovasc Dis. 2014, 23:e221-7. 10.1016\/j.jstrokecerebrovasdis.2013.10.008","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s11936-017-0587-6","article-title":"A diagnostic approach to stroke in young adults","volume":"19","author":"Stack CA","year":"2017","unstructured":"Stack CA, Cole JW. A diagnostic approach to stroke in young adults. Curr Treat Options Cardiovasc Med. 2017, 19:84. 10.1007\/s11936-017-0587-6","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.12.006","article-title":"Clinical impact of thrombophilia screening in young adults with ischemic stroke","volume":"28","author":"Omran SS","year":"2019","unstructured":"Omran SS, Lerario MP, Gialdini G, et al.. Clinical impact of thrombophilia screening in young adults with ischemic stroke. J Stroke Cerebrovasc Dis. 2019, 28:882-9. 10.1016\/j.jstrokecerebrovasdis.2018.12.006","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/svn-2018-000169","article-title":"Utility of current thrombophilia screening in young patients with stroke and TIA","volume":"3","author":"Alakbarzade V","year":"2018","unstructured":"Alakbarzade V, Taylor A, Scully M, Simister R, Chandratheva A. Utility of current thrombophilia screening in young patients with stroke and TIA. Stroke Vasc Neurol. 2018, 3:231-6. 10.1136\/svn-2018-000169","journal-title":"Stroke Vasc Neurol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2015.11.006","article-title":"Thrombophilia testing in young patients with ischemic stroke","volume":"137","author":"Pahus SH","year":"2016","unstructured":"Pahus SH, Hansen AT, Hvas AM. Thrombophilia testing in young patients with ischemic stroke. Thromb Res. 2016, 137:108-12. 10.1016\/j.thromres.2015.11.006","journal-title":"Thromb Res"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.07.032","article-title":"An audit of thrombophilia testing in patients with ischemic stroke or transient ischemic attack: the futility of testing","volume":"27","author":"Gavva C","year":"2018","unstructured":"Gavva C, Johnson M, De Simone N, Sarode R. An audit of thrombophilia testing in patients with ischemic stroke or transient ischemic attack: the futility of testing. J Stroke Cerebrovasc Dis. 2018, 27:3301-5. 10.1016\/j.jstrokecerebrovasdis.2018.07.032","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-012-0325-0","article-title":"Drug abuse and stroke","volume":"13","author":"Fonseca AC","year":"2013","unstructured":"Fonseca AC, Ferro JM. Drug abuse and stroke. Curr Neurol Neurosci Rep. 2013, 13:325. 10.1007\/s11910-012-0325-0","journal-title":"Curr Neurol Neurosci Rep"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2016.07.004","article-title":"Lp(a) and cardiovascular risk: Investigating the hidden side of the moon","volume":"26","author":"Bucci M","year":"2016","unstructured":"Bucci M, Tana C, Giamberardino MA, Cipollone F. Lp(a) and cardiovascular risk: Investigating the hidden side of the moon. Nutr Metab Cardiovasc Dis. 2016, 26:980-6. 10.1016\/j.numecd.2016.07.004","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.07.017","article-title":"Immune-thrombotic thrombocytopenic purpura is a rare cause of ischemic stroke in young adults: case reports and literature review","volume":"27","author":"Tomich C","year":"2018","unstructured":"Tomich C, Debruxelles S, Delmas Y, et al.. Immune-thrombotic thrombocytopenic purpura is a rare cause of ischemic stroke in young adults: case reports and literature review. J Stroke Cerebrovasc Dis. 2018, 27:3163-71. 10.1016\/j.jstrokecerebrovasdis.2018.07.017","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1177\/2396987317703210","article-title":"Searching for explanations for cryptogenic stroke in the young: revealing the triggers, causes, and outcome (SECRETO): rationale and design","volume":"2","author":"Putaala J","year":"2017","unstructured":"Putaala J, Martinez-Majander N, Saeed S, et al.. Searching for explanations for cryptogenic stroke in the young: revealing the triggers, causes, and outcome (SECRETO): rationale and design. Eur Stroke J. 2017, 2:116-25. 10.1177\/2396987317703210","journal-title":"Eur Stroke J"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/85728-contribution-and-effectiveness-of-laboratory-testing-in-the-diagnostic-assessment-of-juvenile-ischemic-stroke-and-transient-ischemic-attack","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:39:21Z","timestamp":1707507561000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/85728-contribution-and-effectiveness-of-laboratory-testing-in-the-diagnostic-assessment-of-juvenile-ischemic-stroke-and-transient-ischemic-attack"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,17]]},"references-count":25,"URL":"https:\/\/doi.org\/10.7759\/cureus.29256","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9,17]]}}}