{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T03:48:15Z","timestamp":1773373695215,"version":"3.50.1"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,10]]},"DOI":"10.7759\/cureus.33624","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T03:55:00Z","timestamp":1673409300000},"source":"Crossref","is-referenced-by-count":1,"title":["Nicorandil, Novel Potassium Adenosine Triphosphate Channel (K+ ATP) Opener in Ischemia\u00a0With\u00a0Non-Obstructive Coronary Arteries (INOCA) and Atherosclerotic Cardiovascular Disease (ASCVD): Delphi Consensus Statement"],"prefix":"10.7759","author":[{"given":"Rabin","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2015.05.003","article-title":"Prevalence, treatments and outcomes of coronary artery disease in Indians: a systematic review","volume":"67","author":"Rao M","year":"2015","unstructured":"Rao M, Xavier D, Devi P, et al.. Prevalence, treatments and outcomes of coronary artery disease in Indians: a systematic review. Indian Heart J. 2015, 67:302-10. 10.1016\/j.ihj.2015.05.003","journal-title":"Indian Heart J"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mjafi.2019.12.005","article-title":"Cardiovascular disease in India: a 360 degree overview","volume":"76","author":"Sreeniwas Kumar A","year":"2020","unstructured":"Sreeniwas Kumar A, Sinha N. Cardiovascular disease in India: a 360 degree overview. Med J Armed Forces India. 2020, 76:1-3. 10.1016\/j.mjafi.2019.12.005","journal-title":"Med J Armed Forces India"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy806","article-title":"Prediction of obstructive coronary artery disease and prognosis in patients with suspected stable angina","volume":"40","author":"Reeh J","year":"2019","unstructured":"Reeh J, Therming CB, Heitmann M, et al.. Prediction of obstructive coronary artery disease and prognosis in patients with suspected stable angina. Eur Heart J. 2019, 40:1426-35. 10.1093\/eurheartj\/ehy806","journal-title":"Eur Heart J"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa503","article-title":"An EAPCI expert consensus document on ischaemia with non-obstructive coronary arteries in collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group","volume":"41","author":"Kunadian V","year":"2020","unstructured":"Kunadian V, Chieffo A, Camici PG, et al.. An EAPCI expert consensus document on ischaemia with non-obstructive coronary arteries in collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. Eur Heart J. 2020, 41:3504-20. 10.1093\/eurheartj\/ehaa503","journal-title":"Eur Heart J"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz425","article-title":"2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes","volume":"41","author":"Knuuti J","year":"2020","unstructured":"Knuuti J, Wijns W, Saraste A, et al.. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J. 2020, 41:407-77. 10.1093\/eurheartj\/ehz425","journal-title":"Eur Heart J"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/4665632","article-title":"Protective effect of nicorandil on cardiac microvascular injury: role of mitochondrial integrity","volume":"2021","author":"Jiang X","year":"2021","unstructured":"Jiang X, Wu D, Jiang Z, Ling W, Qian G. Protective effect of nicorandil on cardiac microvascular injury: role of mitochondrial integrity. Oxid Med Cell Longev. 2021, 2021:4665632. 10.1155\/2021\/4665632","journal-title":"Oxid Med Cell Longev"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s10557-013-6456-y","article-title":"Beneficial effects of intracoronary nicorandil on microvascular dysfunction after primary percutaneous coronary intervention: demonstration of its superiority to nitroglycerin in a cross-over study","volume":"27","author":"Ito N","year":"2013","unstructured":"Ito N, Nanto S, Doi Y, et al.. Beneficial effects of intracoronary nicorandil on microvascular dysfunction after primary percutaneous coronary intervention: demonstration of its superiority to nitroglycerin in a cross-over study. Cardiovasc Drugs Ther. 2013, 27:279-87. 10.1007\/s10557-013-6456-y","journal-title":"Cardiovasc Drugs Ther"},{"key":"ref8","article-title":"Therapeutic effect and safety of nicorandil in treatment of refractory angina pectoris","volume":"11","author":"Li Y","year":"2018","unstructured":"Li Y, Liu Y, Peng W, Wang B, Geng T, Xu Z. Therapeutic effect and safety of nicorandil in treatment of refractory angina pectoris. Int J Clin Exp Med. 2018, 11:6993-8.","journal-title":"Int J Clin Exp Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1987.127","article-title":"Effect of a new coronary vasodilator, nicorandil, on variant angina pectoris","volume":"42","author":"Kishida H","year":"1987","unstructured":"Kishida H, Murao S. Effect of a new coronary vasodilator, nicorandil, on variant angina pectoris. Clin Pharmacol Ther. 1987, 42:166-74. 10.1038\/clpt.1987.127","journal-title":"Clin Pharmacol Ther"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2018.08.002","article-title":"Vasospastic angina: a literature review of current evidence","volume":"112","author":"Picard F","year":"2019","unstructured":"Picard F, Sayah N, Spagnoli V, Adjedj J, Varenne O. Vasospastic angina: a literature review of current evidence. Arch Cardiovasc Dis. 2019, 112:44-55. 10.1016\/j.acvd.2018.08.002","journal-title":"Arch Cardiovasc Dis"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000022167","article-title":"The effect of nicorandil in patients with cardiac syndrome X: a meta-analysis of randomized controlled trials","volume":"99","author":"Jia Q","year":"2020","unstructured":"Jia Q, Shi S, Yuan G, Shi J, Shi S, Wei Y, Hu Y. The effect of nicorandil in patients with cardiac syndrome X: a meta-analysis of randomized controlled trials. Medicine (Baltimore). 2020, 99:e22167. 10.1097\/MD.0000000000022167","journal-title":"Medicine (Baltimore)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023888","article-title":"The effectiveness and safety of nicorandil in the treatment of patients with microvascular angina: a protocol for systematic review and meta-analysis","volume":"100","author":"Zhang Y","year":"2021","unstructured":"Zhang Y, Wang X, Liu R, Li Q, Tian W, Lei H, Shi C. The effectiveness and safety of nicorandil in the treatment of patients with microvascular angina: a protocol for systematic review and meta-analysis. Medicine (Baltimore). 2021, 100:e23888. 10.1097\/MD.0000000000023888","journal-title":"Medicine (Baltimore)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.12659\/msm.902324","article-title":"Cardioprotective effects of nicorandil on coronary heart disease patients undergoing elective percutaneous coronary intervention","volume":"23","author":"Pang Z","year":"2017","unstructured":"Pang Z, Zhao W, Yao Z. Cardioprotective effects of nicorandil on coronary heart disease patients undergoing elective percutaneous coronary intervention. Med Sci Monit. 2017, 23:2924-30. 10.12659\/msm.902324","journal-title":"Med Sci Monit"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S195918","article-title":"Nicorandil prior to primary percutaneous coronary intervention improves clinical outcomes in patients with acute myocardial infarction: a meta-analysis of randomized controlled trials","volume":"13","author":"Xu L","year":"2019","unstructured":"Xu L, Wang L, Li K, Zhang Z, Sun H, Yang X. Nicorandil prior to primary percutaneous coronary intervention improves clinical outcomes in patients with acute myocardial infarction: a meta-analysis of randomized controlled trials. Drug Des Devel Ther. 2019, 13:1389-400. 10.2147\/DDDT.S195918","journal-title":"Drug Des Devel Ther"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-021-02301-1","article-title":"Clinical outcomes of nicorandil administration in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis of randomized controlled trials","volume":"21","author":"Geng N","year":"2021","unstructured":"Geng N, Ren L, Xu L, Zou D, Pang W. Clinical outcomes of nicorandil administration in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis of randomized controlled trials. BMC Cardiovasc Disord. 2021, 21:488. 10.1186\/s12872-021-02301-1","journal-title":"BMC Cardiovasc Disord"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-09-0649","article-title":"Effects of nicorandil on cardiovascular events in patients with coronary artery disease in the Japanese Coronary Artery Disease (JCAD) study","volume":"74","author":"Horinaka S","year":"2010","unstructured":"Horinaka S, Yabe A, Yagi H, et al.. Effects of nicorandil on cardiovascular events in patients with coronary artery disease in the Japanese Coronary Artery Disease (JCAD) study. Circ J. 2010, 74:503-9. 10.1253\/circj.cj-09-0649","journal-title":"Circ J"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV9I9A178","article-title":"Nicorandil prevents microvascular dysfunction resulting from PCI in patients with stable angina pectoris: a randomised study","volume":"9","author":"Hirohata A","year":"2014","unstructured":"Hirohata A, Yamamoto K, Hirose E, et al.. Nicorandil prevents microvascular dysfunction resulting from PCI in patients with stable angina pectoris: a randomised study. EuroIntervention. 2014, 9:1050-6. 10.4244\/EIJV9I9A178","journal-title":"EuroIntervention"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520967856","article-title":"Effect of nicorandil treatment adjunctive to percutaneous coronary intervention in patients with acute myocardial infarction: a systematic review and meta-analysis","volume":"48","author":"Zhou J","year":"2020","unstructured":"Zhou J, Xu J, Cheng A, Li P, Chen B, Sun S. Effect of nicorandil treatment adjunctive to percutaneous coronary intervention in patients with acute myocardial infarction: a systematic review and meta-analysis. J Int Med Res. 2020, 48:300060520967856. 10.1177\/0300060520967856","journal-title":"J Int Med Res"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2011.08.001","article-title":"Oral treatment with nicorandil at discharge is associated with reduced mortality after acute myocardial infarction","volume":"59","author":"Sakata Y","year":"2012","unstructured":"Sakata Y, Nakatani D, Shimizu M, et al.. Oral treatment with nicorandil at discharge is associated with reduced mortality after acute myocardial infarction. J Cardiol. 2012, 59:14-21. 10.1016\/j.jjcc.2011.08.001","journal-title":"J Cardiol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/127647-nicorandil-novel-potassium-adenosine-triphosphate-channel-k-atp-opener-in-ischemiawithnon-obstructive-coronary-arteries-inoca-and-atherosclerotic-cardiovascular-disease-ascvd-delphi-consensus-statement","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:53:29Z","timestamp":1707508409000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/127647-nicorandil-novel-potassium-adenosine-triphosphate-channel-k-atp-opener-in-ischemiawithnon-obstructive-coronary-arteries-inoca-and-atherosclerotic-cardiovascular-disease-ascvd-delphi-consensus-statement"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,10]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.33624","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1,10]]}}}