{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T12:47:03Z","timestamp":1782564423248,"version":"3.54.5"},"reference-count":5,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,11]]},"DOI":"10.7759\/cureus.33658","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T16:20:16Z","timestamp":1673454016000},"source":"Crossref","is-referenced-by-count":4,"title":["Severe Insomnia Induced by Isotretinoin Use for the Management of Acne Vulgaris: A Rare Side Effect"],"prefix":"10.7759","author":[{"given":"Sultan H","family":"Assiri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwaq K","family":"Alosaimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emad A","family":"Alharbi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/sleepj\/zsx050.1030","article-title":"Isotretinoin (13-cis retinoic acid) is associated with a higher frequency of sleep apnea syndrome: results from the US FDA adverse event reporting system (FEARS)","volume":"40","author":"Gupta M","year":"2017","unstructured":"Gupta M, Vujcic B, and Gupta A.. Isotretinoin (13-cis retinoic acid) is associated with a higher frequency of sleep apnea syndrome: results from the US FDA adverse event reporting system (FEARS). Sleep. 2017, 40:A383-4. 10.1093\/sleepj\/zsx050.1030","journal-title":"Sleep"},{"key":"ref2","article-title":"Hypersomnia associated with isotretinoin in a patient with recurrent major depressive disorder and acne vulgaris","volume":"27","author":"Shehi GM","year":"2004","unstructured":"Shehi GM, Bryson WJ.. Hypersomnia associated with isotretinoin in a patient with recurrent major depressive disorder and acne vulgaris. Sleep. 2004, 27:821.","journal-title":"Sleep"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04095.x","article-title":"Effects of isotretinoin treatment on sleep in patients with severe acne: a pilot study","volume":"26","author":"Ismailogullari S","year":"2012","unstructured":"Ismailogullari S, Ferahbas A, Aksu M, Baydemir R, Utas S. Effects of isotretinoin treatment on sleep in patients with severe acne: a pilot study. J Eur Acad Dermatol Venereol. 2012, 26:778-81. 10.1111\/j.1468-3083.2011.04095.x","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.06.573","article-title":"Isotretinoin use in acne is associated with a higher odds of the adverse effect of insomnia: results from the US FDA adverse events reporting system","volume":"83","author":"Gupta M","year":"2020","unstructured":"Gupta M, Vujcic B, Gupta A. Isotretinoin use in acne is associated with a higher odds of the adverse effect of insomnia: results from the US FDA adverse events reporting system. AAD. 2020, 83:121. 10.1016\/j.jaad.2020.06.573","journal-title":"AAD"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.curtheres.2019.01.008","article-title":"Psychiatric and developmental effects of isotretinoin (retinoid) treatment","volume":"90","author":"Suuberg A","year":"2019","unstructured":"Suuberg A. Psychiatric and developmental effects of isotretinoin (retinoid) treatment. Curr Ther Res Clin Exp. 2019, 90:27-31. 10.1016\/j.curtheres.2019.01.008","journal-title":"Curr Ther Res Clin Exp"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/131918-severe-insomnia-induced-by-isotretinoin-use-for-the-management-of-acne-vulgaris-a-rare-side-effect","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:54:29Z","timestamp":1707508469000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/131918-severe-insomnia-induced-by-isotretinoin-use-for-the-management-of-acne-vulgaris-a-rare-side-effect"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,11]]},"references-count":5,"URL":"https:\/\/doi.org\/10.7759\/cureus.33658","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1,11]]}}}