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Vaccine to Be Offered More Widely to Help Control Outbreak\u2014GOV.UK. (2022). Accessed: December 21, 2022: https:\/\/www.gov.uk\/government\/news\/monkeypox-vaccine-to-be-offered-more-widely-to-help-control-outbreak.."},{"key":"ref71","unstructured":"Monkeypox\u2014NYC Health. (2022). Accessed. December 21, 2022: https:\/\/www.nyc.gov\/site\/doh\/health\/health-topics\/monkeypox.page."},{"key":"ref72","unstructured":"2022 monkeypox outbreak global map. (2022). Accessed. December 21, 2022: https:\/\/www.cdc.gov\/poxvirus\/monkeypox\/response\/2022\/world-map.html."},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/154.4.551","article-title":"Human monkeypox: a study of 2,510 contacts of 214 patients","volume":"154","author":"Jezek Z","year":"1986","unstructured":"Jezek Z, Marennikova SS, Mutumbo M, Nakano JH, Paluku KM, Szczeniowski M. Human monkeypox: a study of 2,510 contacts of 214 patients. J Infect Dis. 1986, 154:551-5. 10.1093\/infdis\/154.4.551","journal-title":"J Infect Dis"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/17.3.643","article-title":"The transmission potential of monkeypox virus in human populations","volume":"17","author":"Fine PE","year":"1988","unstructured":"Fine PE, Jezek Z, Grab B, Dixon H. The transmission potential of monkeypox virus in human populations. Int J Epidemiol. 1988, 17:643-50. 10.1093\/ije\/17.3.643","journal-title":"Int J Epidemiol"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005769107","article-title":"Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo","volume":"107","author":"Rimoin AW","year":"2010","unstructured":"Rimoin AW, Mulembakani PM, Johnston SC, et al.. Major increase in human monkeypox incidence 30 years after smallpox vaccination campaigns cease in the Democratic Republic of Congo. 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