{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T16:16:22Z","timestamp":1758125782981},"reference-count":26,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,9]]},"DOI":"10.7759\/cureus.34815","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T22:45:42Z","timestamp":1675982742000},"source":"Crossref","is-referenced-by-count":4,"title":["Vitamin D Deficiency in Saudi Patients With Rheumatoid Arthritis"],"prefix":"10.7759","author":[{"given":"Samar","family":"Alharbi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Razan","family":"Alharbi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enas","family":"Alhabib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reenad","family":"Ghunaim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mawadah M","family":"Alreefi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12072097","article-title":"Immunologic effects of vitamin D on human health and disease","volume":"12","author":"Charoenngam N","year":"2020","unstructured":"Charoenngam N, Holick MF. Immunologic effects of vitamin D on human health and disease. Nutrients. 2020, 12:2097. 10.3390\/nu12072097","journal-title":"Nutrients"},{"key":"ref2","article-title":"Vitamin D deficiency in rheumatoid arthritis. Prevalence and association with disease activity in Western Saudi Arabia","volume":"33","author":"Attar SM","year":"2012","unstructured":"Attar SM. Vitamin D deficiency in rheumatoid arthritis. Prevalence and association with disease activity in Western Saudi Arabia. Saudi Med J. 2012, 33:520-5.","journal-title":"Saudi Med J"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2010.02.011","article-title":"Vitamin D and autoimmune rheumatologic disorders","volume":"9","author":"Pelajo CF","year":"2010","unstructured":"Pelajo CF, Lopez-Benitez JM, Miller LC. Vitamin D and autoimmune rheumatologic disorders. Autoimmun Rev. 2010, 9:507-10. 10.1016\/j.autrev.2010.02.011","journal-title":"Autoimmun Rev"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.069831","article-title":"Vitamin D and autoimmunity: new aetiological and therapeutic considerations","volume":"66","author":"Arnson Y","year":"2007","unstructured":"Arnson Y, Amital H, Shoenfeld Y. Vitamin D and autoimmunity: new aetiological and therapeutic considerations. Ann Rheum Dis. 2007, 66:1137-42. 10.1136\/ard.2007.069831","journal-title":"Ann Rheum Dis"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2008.02127.x","article-title":"The complex role of vitamin D in autoimmune diseases","volume":"68","author":"Szodoray P","year":"2008","unstructured":"Szodoray P, Nakken B, Gaal J, et al.. The complex role of vitamin D in autoimmune diseases. Scand J Immunol. 2008, 68:261-9. 10.1111\/j.1365-3083.2008.02127.x","journal-title":"Scand J Immunol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/ncpendmet0716","article-title":"Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity","volume":"4","author":"Adams JS","year":"2008","unstructured":"Adams JS, Hewison M. Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab. 2008, 4:80-90. 10.1038\/ncpendmet0716","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.6.1678S","article-title":"Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease","volume":"80","author":"Holick MF","year":"2004","unstructured":"Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004, 80:1678-88S. 10.1093\/ajcn\/80.6.1678S","journal-title":"Am J Clin Nutr"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2015.01.036","article-title":"Vitamin D and diabetes: where do we stand?","volume":"108","author":"Mathieu C","year":"2015","unstructured":"Mathieu C. Vitamin D and diabetes: where do we stand?. Diabetes Res Clin Pract. 2015, 108:201-9. 10.1016\/j.diabres.2015.01.036","journal-title":"Diabetes Res Clin Pract"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2011.11.001","article-title":"Vitamin D, multiple sclerosis and inflammatory bowel disease","volume":"523","author":"Cantorna MT","year":"2012","unstructured":"Cantorna MT. Vitamin D, multiple sclerosis and inflammatory bowel disease. Arch Biochem Biophys. 2012, 523:103-6. 10.1016\/j.abb.2011.11.001","journal-title":"Arch Biochem Biophys"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/0961203307085879","article-title":"Review: vitamin D, immunity and lupus","volume":"17","author":"Cutolo M","year":"2008","unstructured":"Cutolo M, Otsa K. Review: vitamin D, immunity and lupus. Lupus. 2008, 17:6-10. 10.1177\/0961203307085879","journal-title":"Lupus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3109\/03009749309099266","article-title":"Low serum vitamin D metabolites in women with rheumatoid arthritis","volume":"22","author":"Kr\u00f6ger H","year":"1993","unstructured":"Kr\u00f6ger H, Penttil\u00e4 IM, Alhava EM. Low serum vitamin D metabolites in women with rheumatoid arthritis. Scand J Rheumatol. 1993, 22:172-7. 10.3109\/03009749309099266","journal-title":"Scand J Rheumatol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-019-00577-2","article-title":"Vitamin D, autoimmune disease and rheumatoid arthritis","volume":"106","author":"Harrison SR","year":"2020","unstructured":"Harrison SR, Li D, Jeffery LE, Raza K, Hewison M. Vitamin D, autoimmune disease and rheumatoid arthritis. Calcif Tissue Int. 2020, 106:58-75. 10.1007\/s00223-019-00577-2","journal-title":"Calcif Tissue Int"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0000000000000340","article-title":"Vitamin D serum level, disease activity and functional ability in different rheumatic patients","volume":"349","author":"Grazio S","year":"2015","unstructured":"Grazio S, Nagli\u0107 \u0110B, Ani\u0107 B, et al.. Vitamin D serum level, disease activity and functional ability in different rheumatic patients. Am J Med Sci. 2015, 349:46-9. 10.1097\/MAJ.0000000000000340","journal-title":"Am J Med Sci"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12426","article-title":"Vitamin D status in rheumatoid arthritis patients: relation to clinical manifestations, disease activity, quality of life and fibromyalgia syndrome","volume":"19","author":"Gheita TA","year":"2016","unstructured":"Gheita TA, Sayed S, Gheita HA, Kenawy SA. Vitamin D status in rheumatoid arthritis patients: relation to clinical manifestations, disease activity, quality of life and fibromyalgia syndrome. Int J Rheum Dis. 2016, 19:294-9. 10.1111\/1756-185X.12426","journal-title":"Int J Rheum Dis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-019-04682-1","article-title":"Serum levels of adiponectin and vitamin D correlate with activity of rheumatoid arthritis","volume":"46","author":"Khajoei S","year":"2019","unstructured":"Khajoei S, Hassaninevisi M, Kianmehr N, et al.. Serum levels of adiponectin and vitamin D correlate with activity of rheumatoid arthritis. Mol Biol Rep. 2019, 46:2505-12. 10.1007\/s11033-019-04682-1","journal-title":"Mol Biol Rep"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2017\/24014.9486","article-title":"The relationship between serum level of vitamin D3 and the severity of new onset rheumatoid arthritis activity","volume":"11","author":"Rajaee E","year":"2017","unstructured":"Rajaee E, Ghorbani A, Mowla K, Zakerkish M, Mohebi M, Dargahi-Malamir M. The relationship between serum level of vitamin D3 and the severity of new onset rheumatoid arthritis activity. J Clin Diagn Res. 2017, 11:OC28-30. 10.7860\/JCDR\/2017\/24014.9486","journal-title":"J Clin Diagn Res"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-013-2174-x","article-title":"The effect of vitamin D levels on the assessment of disease activity in rheumatoid arthritis","volume":"32","author":"Higgins MJ","year":"2013","unstructured":"Higgins MJ, Mackie SL, Thalayasingam N, Bingham SJ, Hamilton J, Kelly CA. The effect of vitamin D levels on the assessment of disease activity in rheumatoid arthritis. Clin Rheumatol. 2013, 32:863-7. 10.1007\/s10067-013-2174-x","journal-title":"Clin Rheumatol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/ar3195","article-title":"Vitamin D deficiency in rheumatoid arthritis: prevalence, determinants and associations with disease activity and disability","volume":"12","author":"Rossini M","year":"2010","unstructured":"Rossini M, Maddali Bongi S, La Montagna G, et al.. Vitamin D deficiency in rheumatoid arthritis: prevalence, determinants and associations with disease activity and disability. Arthritis Res Ther. 2010, 12:R216. 10.1186\/ar3195","journal-title":"Arthritis Res Ther"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/260725","article-title":"Vitamin D is a good marker for disease activity of rheumatoid arthritis disease","volume":"2015","author":"Azzeh FS","year":"2015","unstructured":"Azzeh FS, Kensara OA. Vitamin D is a good marker for disease activity of rheumatoid arthritis disease. Dis Markers. 2015, 2015:260725. 10.1155\/2015\/260725","journal-title":"Dis Markers"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-010-1393-6","article-title":"The relationship between vitamin D and disease activity and functional health status in rheumatoid arthritis","volume":"31","author":"Turhano\u011flu AD","year":"2011","unstructured":"Turhano\u011flu AD, G\u00fcler H, Y\u00f6nden Z, Aslan F, Mansuroglu A, Ozer C. The relationship between vitamin D and disease activity and functional health status in rheumatoid arthritis. Rheumatol Int. 2011, 31:911-4. 10.1007\/s00296-010-1393-6","journal-title":"Rheumatol Int"},{"key":"ref21","article-title":"Circannual vitamin d serum levels and disease activity in rheumatoid arthritis: Northern versus Southern Europe","volume":"24","author":"Cutolo M","year":"2006","unstructured":"Cutolo M, Otsa K, Laas K, et al.. Circannual vitamin d serum levels and disease activity in rheumatoid arthritis: Northern versus Southern Europe. Clin Exp Rheumatol. 2006, 24:702-4.","journal-title":"Clin Exp Rheumatol"},{"key":"ref22","article-title":"Serum 25-hydroxyvitamin D concentration in patients with psoriasis and rheumatoid arthritis and its association with disease activity and serum tumor necrosis factor-alpha","volume":"34","author":"Atwa MA","year":"2013","unstructured":"Atwa MA, Balata MG, Hussein AM, Abdelrahman NI, Elminshawy HH. Serum 25-hydroxyvitamin D concentration in patients with psoriasis and rheumatoid arthritis and its association with disease activity and serum tumor necrosis factor-alpha. Saudi Med J. 2013, 34:806-13.","journal-title":"Saudi Med J"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.090705","article-title":"Vitamin D status and its associations with disease activity and severity in African Americans with recent-onset rheumatoid arthritis","volume":"37","author":"Craig SM","year":"2010","unstructured":"Craig SM, Yu F, Curtis JR, et al.. Vitamin D status and its associations with disease activity and severity in African Americans with recent-onset rheumatoid arthritis. J Rheumatol. 2010, 37:275-81. 10.3899\/jrheum.090705","journal-title":"J Rheumatol"},{"key":"ref24","article-title":"Associations between vitamin D, disease activity, and clinical response to therapy in rheumatoid arthritis","volume":"30","author":"Baker JF","year":"2012","unstructured":"Baker JF, Baker DG, Toedter G, Shults J, Von Feldt JM, Leonard MB. Associations between vitamin D, disease activity, and clinical response to therapy in rheumatoid arthritis. Clin Exp Rheumatol. 2012, 30:658-64.","journal-title":"Clin Exp Rheumatol"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04875.x","article-title":"Vitamin D metabolites as clinical markers in autoimmune and chronic disease","volume":"1173","author":"Blaney GP","year":"2009","unstructured":"Blaney GP, Albert PJ, Proal AD. Vitamin D metabolites as clinical markers in autoimmune and chronic disease. Ann N Y Acad Sci. 2009, 1173:384-90. 10.1111\/j.1749-6632.2009.04875.x","journal-title":"Ann N Y Acad Sci"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1002\/art.11434","article-title":"Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study","volume":"50","author":"Merlino LA","year":"2004","unstructured":"Merlino LA, Curtis J, Mikuls TR, Cerhan JR, Criswell LA, Saag KG. Vitamin D intake is inversely associated with rheumatoid arthritis: results from the Iowa Women's Health Study. Arthritis Rheum. 2004, 50:72-7. 10.1002\/art.11434","journal-title":"Arthritis Rheum"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/136968-vitamin-d-deficiency-in-saudi-patients-with-rheumatoid-arthritis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:58:53Z","timestamp":1707508733000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/136968-vitamin-d-deficiency-in-saudi-patients-with-rheumatoid-arthritis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,9]]},"references-count":26,"URL":"https:\/\/doi.org\/10.7759\/cureus.34815","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2,9]]}}}