{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:42:59Z","timestamp":1764175379341},"reference-count":35,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,2]]},"DOI":"10.7759\/cureus.35690","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T15:11:01Z","timestamp":1677769861000},"source":"Crossref","is-referenced-by-count":4,"title":["Association Between Follicle-Stimulating Hormone Receptor (FSHR) rs6166 and Estrogen Receptor 1 (ESR1) rs2234693 Polymorphisms and Polycystic Ovary Syndrome Risk, Phenotype, and Reproductive Outcomes in an Infertile Portuguese Population"],"prefix":"10.7759","author":[{"given":"In\u00eas H","family":"Vieira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra F","family":"Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Almeida Reis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L","family":"Carreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Concei\u00e7\u00e3o","family":"Dias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Filipa","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dircea","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Paula","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Ramalho-Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Cristina","family":"Ramalhinho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Moura Ramos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Paiva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Cortes\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Teresa","family":"Almeida-Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep399","article-title":"The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria","volume":"25","author":"March WA","year":"2010","unstructured":"March WA, Moore VM, Willson KJ, Phillips DI, Norman RJ, Davies MJ. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum Reprod. 2010, 25:544-51. 10.1093\/humrep\/dep399","journal-title":"Hum Reprod"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1210\/er.2015-1018","article-title":"Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome","volume":"36","author":"Dumesic DA","year":"2015","unstructured":"Dumesic DA, Oberfield SE, Stener-Victorin E, Marshall JC, Laven JS, Legro RS. Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. Endocr Rev. 2015, 36:487-525. 10.1210\/er.2015-1018","journal-title":"Endocr Rev"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)04800-8","article-title":"Effects of metformin on body mass index, menstrual cyclicity, and ovulation induction in women with polycystic ovary syndrome","volume":"79","author":"Haas DA","year":"2003","unstructured":"Haas DA, Carr BR, Attia GR. Effects of metformin on body mass index, menstrual cyclicity, and ovulation induction in women with polycystic ovary syndrome. Fertil Steril. 2003, 79:469-81. 10.1016\/S0015-0282(02)04800-8","journal-title":"Fertil Steril"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-009-9308-8","article-title":"Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome","volume":"26","author":"Unsal T","year":"2009","unstructured":"Unsal T, Konac E, Yesilkaya E, et al.. Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome. J Assist Reprod Genet. 2009, 26:205-16. 10.1007\/s10815-009-9308-8","journal-title":"J Assist Reprod Genet"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem426","article-title":"Consensus on infertility treatment related to polycystic ovary syndrome","volume":"23","author":"Thessaloniki ESHRE\/ASRM-Sponsored PCOS Consensus Workshop Group","year":"2008","unstructured":"Thessaloniki ESHRE\/ASRM-Sponsored PCOS Consensus Workshop Group. Consensus on infertility treatment related to polycystic ovary syndrome. Hum Reprod. 2008, 23:462-77. 10.1093\/humrep\/dem426","journal-title":"Hum Reprod"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/5.9.797","article-title":"Association of oestrogen receptor gene polymorphisms with outcome of ovarian stimulation in patients undergoing IVF","volume":"5","author":"Sundarrajan C","year":"1999","unstructured":"Sundarrajan C, Liao W, Roy AC, Ng SC. Association of oestrogen receptor gene polymorphisms with outcome of ovarian stimulation in patients undergoing IVF. Mol Hum Reprod. 1999, 5:797-802. 10.1093\/molehr\/5.9.797","journal-title":"Mol Hum Reprod"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1530\/REP-15-0251","article-title":"Impact of gene polymorphisms of gonadotropins and their receptors on human reproductive success","volume":"150","author":"Casarini L","year":"2015","unstructured":"Casarini L, Santi D, Marino M. Impact of gene polymorphisms of gonadotropins and their receptors on human reproductive success. Reproduction. 2015, 150:R175-84. 10.1530\/REP-15-0251","journal-title":"Reproduction"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-013-0166-z","article-title":"Association between FSHR polymorphisms and polycystic ovary syndrome among Chinese women in north China","volume":"31","author":"Wu XQ","year":"2014","unstructured":"Wu XQ, Xu SM, Liu JF, Bi XY, Wu YX, Liu J. Association between FSHR polymorphisms and polycystic ovary syndrome among Chinese women in north China. J Assist Reprod Genet. 2014, 31:371-7. 10.1007\/s10815-013-0166-z","journal-title":"J Assist Reprod Genet"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-015-0427-0","article-title":"Leutinizing hormone\/choriogonadotropin receptor and follicle stimulating hormone receptor gene variants in polycystic ovary syndrome","volume":"32","author":"Almawi WY","year":"2015","unstructured":"Almawi WY, Hubail B, Arekat DZ, et al.. Leutinizing hormone\/choriogonadotropin receptor and follicle stimulating hormone receptor gene variants in polycystic ovary syndrome. J Assist Reprod Genet. 2015, 32:607-14. 10.1007\/s10815-015-0427-0","journal-title":"J Assist Reprod Genet"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2011.633649","article-title":"PCOS and peripheral AMH levels in relation to FSH receptor gene single nucleotide polymorphisms","volume":"28","author":"Mohiyiddeen L","year":"2012","unstructured":"Mohiyiddeen L, Salim S, Mulugeta B, McBurney H, Newman WG, Pemberton P, Nardo LG. PCOS and peripheral AMH levels in relation to FSH receptor gene single nucleotide polymorphisms. Gynecol Endocrinol. 2012, 28:375-7. 10.3109\/09513590.2011.633649","journal-title":"Gynecol Endocrinol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-017-0953-z","article-title":"FSH receptor gene p. Thr307Ala and p. Asn680Ser polymorphisms are associated with the risk of polycystic ovary syndrome","volume":"34","author":"Kim JJ","year":"2017","unstructured":"Kim JJ, Choi YM, Hong MA, et al.. FSH receptor gene p. Thr307Ala and p. Asn680Ser polymorphisms are associated with the risk of polycystic ovary syndrome. J Assist Reprod Genet. 2017, 34:1087-93. 10.1007\/s10815-017-0953-z","journal-title":"J Assist Reprod Genet"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der222","article-title":"Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome","volume":"26","author":"Valkenburg O","year":"2011","unstructured":"Valkenburg O, Uitterlinden AG, Themmen AP, de Jong FH, Hofman A, Fauser BC, Laven JS. Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome. Hum Reprod. 2011, 26:2902-11. 10.1093\/humrep\/der222","journal-title":"Hum Reprod"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep114","article-title":"Clomiphene citrate resistance in relation to follicle-stimulating hormone receptor Ser680Ser-polymorphism in polycystic ovary syndrome","volume":"24","author":"Overbeek A","year":"2009","unstructured":"Overbeek A, Kuijper EA, Hendriks ML, et al.. Clomiphene citrate resistance in relation to follicle-stimulating hormone receptor Ser680Ser-polymorphism in polycystic ovary syndrome. Hum Reprod. 2009, 24:2007-13. 10.1093\/humrep\/dep114","journal-title":"Hum Reprod"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.1.7098","article-title":"Association between estrogen receptor-beta gene polymorphisms and ovulatory dysfunctions in patients with menstrual disorders","volume":"86","author":"Sundarrajan C","year":"2001","unstructured":"Sundarrajan C, Liao WX, Roy AC, Ng SC. Association between estrogen receptor-beta gene polymorphisms and ovulatory dysfunctions in patients with menstrual disorders. J Clin Endocrinol Metab. 2001, 86:135-9. 10.1210\/jcem.86.1.7098","journal-title":"J Clin Endocrinol Metab"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1177\/1933719114542015","article-title":"Genetic polymorphisms in Pakistani women with polycystic ovary syndrome","volume":"22","author":"Liaqat I","year":"2015","unstructured":"Liaqat I, Jahan N, Krikun G, Taylor HS. Genetic polymorphisms in Pakistani women with polycystic ovary syndrome. Reprod Sci. 2015, 22:347-57. 10.1177\/1933719114542015","journal-title":"Reprod Sci"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr034","article-title":"Genetic predictors of controlled ovarian hyperstimulation: where do we stand today?","volume":"17","author":"Altm\u00e4e S","year":"2011","unstructured":"Altm\u00e4e S, Hovatta O, Stavreus-Evers A, Salumets A. Genetic predictors of controlled ovarian hyperstimulation: where do we stand today?. Hum Reprod Update. 2011, 17:813-28. 10.1093\/humupd\/dmr034","journal-title":"Hum Reprod Update"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00398","article-title":"Pharmacogenetics of FSH action in the female","volume":"10","author":"Conforti A","year":"2019","unstructured":"Conforti A, Vaiarelli A, Cimadomo D, et al.. Pharmacogenetics of FSH action in the female. Front Endocrinol (Lausanne). 2019, 10:398. 10.3389\/fendo.2019.00398","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.10.004","article-title":"Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome","volume":"81","author":"Rotterdam ESHRE\/ASRM-Sponsored PCOS Consensus Workshop Group","year":"2004","unstructured":"Rotterdam ESHRE\/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004, 81:19-25. 10.1016\/j.fertnstert.2003.10.004","journal-title":"Fertil Steril"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2019.03.203","article-title":"A meta-analysis of pregnancy-related outcomes and complications in women with polycystic ovary syndrome undergoing IVF","volume":"39","author":"Sha T","year":"2019","unstructured":"Sha T, Wang X, Cheng W, Yan Y. A meta-analysis of pregnancy-related outcomes and complications in women with polycystic ovary syndrome undergoing IVF. Reprod Biomed Online. 2019, 39:281-93. 10.1016\/j.rbmo.2019.03.203","journal-title":"Reprod Biomed Online"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-12-86","article-title":"Follicle-stimulating hormone receptor gene polymorphism in chronic anovulatory women, with or without polycystic ovary syndrome: a cross-sectional study","volume":"12","author":"Singhasena W","year":"2014","unstructured":"Singhasena W, Pantasri T, Piromlertamorn W, Samchimchom S, Vutyavanich T. Follicle-stimulating hormone receptor gene polymorphism in chronic anovulatory women, with or without polycystic ovary syndrome: a cross-sectional study. Reprod Biol Endocrinol. 2014, 12:86. 10.1186\/1477-7827-12-86","journal-title":"Reprod Biol Endocrinol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209830","article-title":"Identification of selected genetic polymorphisms in polycystic ovary syndrome in Sri Lankan women using low cost genotyping techniques","volume":"13","author":"Branavan U","year":"2018","unstructured":"Branavan U, Muneeswaran K, Wijesundera S, Jayakody S, Chandrasekharan V, Wijeyaratne C. Identification of selected genetic polymorphisms in polycystic ovary syndrome in Sri Lankan women using low cost genotyping techniques. PLoS One. 2018, 13:e0209830. 10.1371\/journal.pone.0209830","journal-title":"PLoS One"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-021-02291-1","article-title":"Replication study and meta-analysis of selected genetic variants and polycystic ovary syndrome susceptibility in Asian population","volume":"38","author":"Wan P","year":"2021","unstructured":"Wan P, Meng L, Huang C, et al.. Replication study and meta-analysis of selected genetic variants and polycystic ovary syndrome susceptibility in Asian population. J Assist Reprod Genet. 2021, 38:2781-9. 10.1007\/s10815-021-02291-1","journal-title":"J Assist Reprod Genet"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm_00000441","article-title":"Genetic variations of follicle stimulating hormone receptor are associated with polycystic ovary syndrome","volume":"26","author":"Gu BH","year":"2010","unstructured":"Gu BH, Park JM, Baek KH. Genetic variations of follicle stimulating hormone receptor are associated with polycystic ovary syndrome. Int J Mol Med. 2010, 26:107-12. 10.3892\/ijmm_00000441","journal-title":"Int J Mol Med"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-011-9619-4","article-title":"FSH-receptor Ala307Thr polymorphism is associated to polycystic ovary syndrome and to a higher responsiveness to exogenous FSH in Italian women","volume":"28","author":"Dolfin E","year":"2011","unstructured":"Dolfin E, Guani B, Lussiana C, Mari C, Restagno G, Revelli A. FSH-receptor Ala307Thr polymorphism is associated to polycystic ovary syndrome and to a higher responsiveness to exogenous FSH in Italian women. J Assist Reprod Genet. 2011, 28:925-30. 10.1007\/s10815-011-9619-4","journal-title":"J Assist Reprod Genet"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.12.040","article-title":"Estrogen receptor beta gene +1730 G\/A polymorphism in women with polycystic ovary syndrome","volume":"93","author":"Kim JJ","year":"2010","unstructured":"Kim JJ, Choi YM, Choung SH, Yoon SH, Lee GH, Moon SY. Estrogen receptor beta gene +1730 G\/A polymorphism in women with polycystic ovary syndrome. Fertil Steril. 2010, 93:1942-7. 10.1016\/j.fertnstert.2008.12.040","journal-title":"Fertil Steril"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2018.00504","article-title":"Variant alleles of the ESR1, PPARG, HMGA2, and MTHFR genes are associated with polycystic ovary syndrome risk in a Chinese population: a case-control study","volume":"9","author":"Jiao X","year":"2018","unstructured":"Jiao X, Chen W, Zhang J, et al.. Variant alleles of the ESR1, PPARG, HMGA2, and MTHFR genes are associated with polycystic ovary syndrome risk in a Chinese population: a case-control study. Front Endocrinol (Lausanne). 2018, 9:504. 10.3389\/fendo.2018.00504","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2015.01.037","article-title":"Estrogen receptor \u03b1lpha gene (ESR1) PvuII and XbaI polymorphisms are associated to metabolic and proinflammatory factors in polycystic ovary syndrome","volume":"560","author":"Silva FS","year":"2015","unstructured":"Silva FS, S\u00f3ter MO, Sales MF, et al.. Estrogen receptor \u03b1lpha gene (ESR1) PvuII and XbaI polymorphisms are associated to metabolic and proinflammatory factors in polycystic ovary syndrome. Gene. 2015, 560:44-9. 10.1016\/j.gene.2015.01.037","journal-title":"Gene"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19053114","article-title":"Biochemical characterization and molecular determination of estrogen receptor-\u03b1 (ESR1 PvuII-rs2234693 T>C) and MiRNA-146a (rs2910164 C>G) polymorphic gene variations and their association with the risk of polycystic ovary syndrome","volume":"19","author":"Mir R","year":"2022","unstructured":"Mir R, Tayeb FJ, Barnawi J, et al.. Biochemical characterization and molecular determination of estrogen receptor-\u03b1 (ESR1 PvuII-rs2234693 T&gt;C) and MiRNA-146a (rs2910164 C&gt;G) polymorphic gene variations and their association with the risk of polycystic ovary syndrome. Int J Environ Res Public Health. 2022, 19:3114. 10.3390\/ijerph19053114","journal-title":"Int J Environ Res Public Health"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.726184","article-title":"Association of estrogen receptor genes polymorphisms with polycystic ovary syndrome: a systematic review and meta-analysis based on observational studies","volume":"12","author":"Zhou S","year":"2021","unstructured":"Zhou S, Wen S, Sheng Y, et al.. Association of estrogen receptor genes polymorphisms with polycystic ovary syndrome: a systematic review and meta-analysis based on observational studies. Front Endocrinol (Lausanne). 2021, 12:726184. 10.3389\/fendo.2021.726184","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00023","article-title":"Follicle stimulating hormone receptor (FSHR) Polymorphisms and polycystic ovary syndrome (PCOS)","volume":"10","author":"Laven JS","year":"2019","unstructured":"Laven JS. Follicle stimulating hormone receptor (FSHR) Polymorphisms and polycystic ovary syndrome (PCOS). Front Endocrinol (Lausanne). 2019, 10:23. 10.3389\/fendo.2019.00023","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1007\/s43032-020-00375-4","article-title":"A comprehensive overview of common polymorphic variants in genes related to polycystic ovary syndrome","volume":"28","author":"Castillo-Higuera T","year":"2021","unstructured":"Castillo-Higuera T, Alarc\u00f3n-Granados MC, Marin-Suarez J, et al.. A comprehensive overview of common polymorphic variants in genes related to polycystic ovary syndrome. Reprod Sci. 2021, 28:2399-412. 10.1007\/s43032-020-00375-4","journal-title":"Reprod Sci"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s10038-006-0005-5","article-title":"Follicle-stimulating hormone receptor gene polymorphism and ovarian responses to controlled ovarian hyperstimulation for IVF-ET","volume":"51","author":"Jun JK","year":"2006","unstructured":"Jun JK, Yoon JS, Ku SY, et al.. Follicle-stimulating hormone receptor gene polymorphism and ovarian responses to controlled ovarian hyperstimulation for IVF-ET. J Hum Genet. 2006, 51:665-70. 10.1007\/s10038-006-0005-5","journal-title":"J Hum Genet"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1097\/01.fpc.0000167330.92786.5e","article-title":"Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation","volume":"15","author":"Behre HM","year":"2005","unstructured":"Behre HM, Greb RR, Mempel A, et al.. Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation. Pharmacogenet Genomics. 2005, 15:451-6. 10.1097\/01.fpc.0000167330.92786.5e","journal-title":"Pharmacogenet Genomics"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-005-9015-z","article-title":"FSH receptor gene polymorphisms have a role for different ovarian response to stimulation in patients entering IVF\/ICSI-ET programs","volume":"23","author":"Loutradis D","year":"2006","unstructured":"Loutradis D, Patsoula E, Minas V, Koussidis GA, Antsaklis A, Michalas S, Makrigiannakis A. FSH receptor gene polymorphisms have a role for different ovarian response to stimulation in patients entering IVF\/ICSI-ET programs. J Assist Reprod Genet. 2006, 23:177-84. 10.1007\/s10815-005-9015-z","journal-title":"J Assist Reprod Genet"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/12.7.1430","article-title":"Oestrogen receptor gene polymorphisms and ovarian stimulation for in-vitro fertilization","volume":"12","author":"Georgiou I","year":"1997","unstructured":"Georgiou I, Konstantelli M, Syrrou M, Messinis IE, Lolis DE. Oestrogen receptor gene polymorphisms and ovarian stimulation for in-vitro fertilization. Hum Reprod. 1997, 12:1430-3. 10.1093\/humrep\/12.7.1430","journal-title":"Hum Reprod"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/131814-association-between-follicle-stimulating-hormone-receptor-fshr-rs6166-and-estrogen-receptor-1-esr1-rs2234693-polymorphisms-and-polycystic-ovary-syndrome-risk-phenotype-and-reproductive-outcomes-in-an-infertile-portuguese-population","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:59:40Z","timestamp":1707508780000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/131814-association-between-follicle-stimulating-hormone-receptor-fshr-rs6166-and-estrogen-receptor-1-esr1-rs2234693-polymorphisms-and-polycystic-ovary-syndrome-risk-phenotype-and-reproductive-outcomes-in-an-infertile-portuguese-population"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,2]]},"references-count":35,"URL":"https:\/\/doi.org\/10.7759\/cureus.35690","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,2]]}}}