{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T11:42:00Z","timestamp":1781091720419,"version":"3.54.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,15]]},"DOI":"10.7759\/cureus.36172","type":"journal-article","created":{"date-parts":[[2023,3,15]],"date-time":"2023-03-15T10:39:52Z","timestamp":1678876792000},"source":"Crossref","is-referenced-by-count":6,"title":["Suicide Attempt With Levothyroxine Overdose"],"prefix":"10.7759","author":[{"given":"Angad S","family":"Gill","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harpreet K","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhijana","family":"Karunakaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Chaudhuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2006.0235","article-title":"Serum TSH and total T4 in the United States population and their association with participant characteristics: National Health and Nutrition Examination Survey (NHANES 1999-2002)","volume":"17","author":"Aoki Y","year":"2007","unstructured":"Aoki Y, Belin RM, Clickner R, Jeffries R, Phillips L, Mahaffey KR. Serum TSH and total T4 in the United States population and their association with participant characteristics: National Health and Nutrition Examination Survey (NHANES 1999-2002). Thyroid. 2007, 17:1211-23. 10.1089\/thy.2006.0235","journal-title":"Thyroid"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0028","article-title":"Guidelines for the treatment of hypothyroidism: prepared by the American Thyroid Association task force on thyroid hormone replacement","volume":"24","author":"Jonklaas J","year":"2014","unstructured":"Jonklaas J, Bianco AC, Bauer AJ, et al.. Guidelines for the treatment of hypothyroidism: prepared by the American Thyroid Association task force on thyroid hormone replacement. Thyroid. 2014, 24:1670-751. 10.1089\/thy.2014.0028","journal-title":"Thyroid"},{"key":"ref3","article-title":"Thyroid hormone","author":"Cantrell FL","year":"2022","unstructured":"Cantrell FL. Thyroid hormone. Poisoning and Drug Overdose. Olson KR, Smollin CG, Anderson IB (ed): McGraw Hill, New York, NY; 2022."},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1017\/cem.2014.75","article-title":"Case report: clues to the diagnosis of an unsuspected massive levothyroxine overdose","volume":"17","author":"Allen KM","year":"2015","unstructured":"Allen KM, Crawford VB, Conaglen JV, Elston MS. Case report: clues to the diagnosis of an unsuspected massive levothyroxine overdose. CJEM. 2015, 17:692-8. 10.1017\/cem.2014.75","journal-title":"CJEM"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00856","article-title":"Can reverse T3 assay be employed to guide T4 vs. T4\/T3 therapy in hypothyroidism?","volume":"10","author":"Gomes-Lima C","year":"2019","unstructured":"Gomes-Lima C, Wartofsky L, Burman K. Can reverse T3 assay be employed to guide T4 vs. T4\/T3 therapy in hypothyroidism?. Front Endocrinol (Lausanne). 2019, 10:856. 10.3389\/fendo.2019.00856","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref6","doi-asserted-by":"crossref","DOI":"10.1542\/peds.73.3.313","article-title":"Acute ingestions of thyroid hormones","volume":"73","author":"Lehrner LM","year":"1984","unstructured":"Lehrner LM, Weir MR. Acute ingestions of thyroid hormones. Pediatrics. 1984, 73:313-7.","journal-title":"Pediatrics"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000010909","article-title":"No obvious sympathetic excitation after massive levothyroxine overdose: a case report","volume":"97","author":"Xue J","year":"2018","unstructured":"Xue J, Zhang L, Qin Z, et al.. No obvious sympathetic excitation after massive levothyroxine overdose: a case report. Medicine (Baltimore). 2018, 97:e10909. 10.1097\/MD.0000000000010909","journal-title":"Medicine (Baltimore)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.17925\/EE.2013.09.01.40","article-title":"A review of the pharmacokinetics of levothyroxine for the treatment of hypothyroidism","volume":"9","author":"Colucci P","year":"2013","unstructured":"Colucci P, Yue CS, Ducharme M, Benvenga S. A review of the pharmacokinetics of levothyroxine for the treatment of hypothyroidism. Eur Endocrinol. 2013, 9:40-7. 10.17925\/EE.2013.09.01.40","journal-title":"Eur Endocrinol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1530\/acta.0.1080351","article-title":"The effect of propranolol on circulating thyroid hormone measurements in thyrotoxic and euthyroid subjects","volume":"108","author":"Franklyn JA","year":"1985","unstructured":"Franklyn JA, Wilkins MR, Wilkinson R, Ramsden DB, Sheppard MC. The effect of propranolol on circulating thyroid hormone measurements in thyrotoxic and euthyroid subjects. Acta Endocrinol (Copenh). 1985, 108:351-5. 10.1530\/acta.0.1080351","journal-title":"Acta Endocrinol (Copenh)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-45-2-293","article-title":"The influence of beta-adrenoceptor blocking agents on plasma thyroxine and triiodothyronine","volume":"45","author":"Wiersinga WM","year":"1977","unstructured":"Wiersinga WM, Touber JL. The influence of beta-adrenoceptor blocking agents on plasma thyroxine and triiodothyronine. J Clin Endocrinol Metab. 1977, 45:293-8. 10.1210\/jcem-45-2-293","journal-title":"J Clin Endocrinol Metab"},{"key":"ref11","article-title":"Massive thyroid hormone overdose: kinetics, clinical manifestations and management","volume":"4","author":"Shilo L","year":"2002","unstructured":"Shilo L, Kovatz S, Hadari R, Weiss E, Nabriski D, Shenkman L. Massive thyroid hormone overdose: kinetics, clinical manifestations and management. Isr Med Assoc J. 2002, 4:298-9.","journal-title":"Isr Med Assoc J"},{"key":"ref12","article-title":"Thyroxine Poisoning","author":"Medeiros-Neto G","year":"2000","unstructured":"Medeiros-Neto G, Feingold KR, Anawalt B. Thyroxine Poisoning. MDText.com, Inc., South Dartmouth, MA; 2000."},{"key":"ref13","doi-asserted-by":"crossref","DOI":"10.1001\/jama.1985.03360150085029","article-title":"Levothyroxine overdose associated with seizures in a young child","volume":"254","author":"Kulig K","year":"1985","unstructured":"Kulig K, Golightly LK, Rumack BH. Levothyroxine overdose associated with seizures in a young child. JAMA. 1985, 254:2109-10.","journal-title":"JAMA"},{"key":"ref14","doi-asserted-by":"crossref","DOI":"10.1542\/peds.84.2.262","article-title":"Acute thyroxine ingestion in pediatric patients","volume":"84","author":"Lewander WJ","year":"1989","unstructured":"Lewander WJ, Lacouture PG, Silva JE, Lovejoy FH. Acute thyroxine ingestion in pediatric patients. Pediatrics. 1989, 84:262-5.","journal-title":"Pediatrics"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.21037\/apm-20-190","article-title":"Plasmapheresis in the treatment of multi-drug intoxication involving levothyroxine sodium and calcium channel blockers: a case report","volume":"10","author":"Li R","year":"2021","unstructured":"Li R, Xu YW, Xue Y, Wu XZ. Plasmapheresis in the treatment of multi-drug intoxication involving levothyroxine sodium and calcium channel blockers: a case report. Ann Palliat Med. 2021, 10:5839-45. 10.21037\/apm-20-190","journal-title":"Ann Palliat Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3109\/15563658308990617","article-title":"Plasmapheresis in thyroxine overdose: a case report","volume":"20","author":"May ME","year":"1983","unstructured":"May ME, Mintz PD, Lowry P, Geller R, Curnow RT. Plasmapheresis in thyroxine overdose: a case report. J Toxicol Clin Toxicol. 1983, 20:517-20. 10.3109\/15563658308990617","journal-title":"J Toxicol Clin Toxicol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg1049","article-title":"Current applications of plasmapheresis in clinical toxicology","volume":"18 Suppl 5","author":"Nenov VD","year":"2003","unstructured":"Nenov VD, Marinov P, Sabeva J, Nenov DS. Current applications of plasmapheresis in clinical toxicology. Nephrol Dial Transplant. 2003, 18 Suppl 5:v56-8. 10.1093\/ndt\/gfg1049","journal-title":"Nephrol Dial Transplant"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1081\/clt-120039801","article-title":"Position paper: cathartics","volume":"42","year":"2004","unstructured":"Position paper. cathartics. J Toxicol Clin Toxicol. 2004, 42:243-53. 10.1081\/clt-120039801","journal-title":"J Toxicol Clin Toxicol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/143395-suicide-attempt-with-levothyroxine-overdose","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:55:21Z","timestamp":1707508521000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/143395-suicide-attempt-with-levothyroxine-overdose"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,15]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.36172","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,15]]}}}