{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T23:01:02Z","timestamp":1789599662731,"version":"build-2803163510"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,30]]},"DOI":"10.7759\/cureus.36908","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T14:09:22Z","timestamp":1680185362000},"source":"Crossref","is-referenced-by-count":3,"title":["A Comparative Evaluation of Soft and Hard Tissue Changes Around Dental Implants Placed With and Without Platelet-Rich Fibrin"],"prefix":"10.7759","author":[{"given":"Kanchan","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suparna","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archana","family":"Kumari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marupaka","family":"Bhargavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumati","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasad","family":"Ingale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Laddha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.249_13358","article-title":"Patient information on treatment alternatives for missing single teeth - systematic review","volume":"9","author":"Edelmayer M","year":"2016","unstructured":"Edelmayer M, Woletz K, Ulm C, Zechner W, Tepper G. Patient information on treatment alternatives for missing single teeth - systematic review. Eur J Oral Implantol. 2016, 9:45-57. 10.1111\/clr.249_13358","journal-title":"Eur J Oral Implantol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.5772\/16477","article-title":"Crestal bone level alterations in implant therapy","author":"Koutouzis T","year":"2011","unstructured":"Koutouzis T. Crestal bone level alterations in implant therapy. Implant Dentistry - A Rapidly Evolving Practice. IntechOpen, London; 2011. 10.5772\/16477"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1994.tb00006.x","article-title":"Biological aspects of implant dentistry: osseointegration","volume":"4","author":"Albrektsson TO","year":"1994","unstructured":"Albrektsson TO, Johansson CB, Sennerby L. Biological aspects of implant dentistry: osseointegration. Periodontol 2000. 1994, 4:58-73. 10.1111\/j.1600-0757.1994.tb00006.x","journal-title":"Periodontol 2000"},{"key":"ref4","article-title":"The maintenance of crestal bone around dental implants","author":"Alshehri MA","year":"2011","unstructured":"Alshehri MA. The maintenance of crestal bone around dental implants. Implants. 2011, 20-4.","journal-title":"Implants"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.11607\/prd.1945","article-title":"Provisional restorations used in immediate implant placement provide a platform to promote peri-implant soft tissue healing: a pilot study","volume":"36","author":"Saito H","year":"2016","unstructured":"Saito H, Chu SJ, Reynolds MA, Tarnow DP. Provisional restorations used in immediate implant placement provide a platform to promote peri-implant soft tissue healing: a pilot study. Int J Periodontics Restorative Dent. 2016, 36:47-52. 10.11607\/prd.1945","journal-title":"Int J Periodontics Restorative Dent"},{"key":"ref6","article-title":"The long-term efficacy of currently used dental implants: a review and proposed criteria of success","volume":"1","author":"Albrektsson T","year":"1986","unstructured":"Albrektsson T, Zarb G, Worthington P, Eriksson AR. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants. 1986, 1:11-25.","journal-title":"Int J Oral Maxillofac Implants"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2010.00327.x","article-title":"Soft tissue attachment to titanium implants coated with growth factors","volume":"15","author":"Bates C","year":"2013","unstructured":"Bates C, Marino V, Fazzalari NL, Bartold PM. Soft tissue attachment to titanium implants coated with growth factors. Clin Implant Dent Relat Res. 2013, 15:53-63. 10.1111\/j.1708-8208.2010.00327.x","journal-title":"Clin Implant Dent Relat Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1563\/aaid-joi-D-13-00304","article-title":"Efficacy of growth factor in promoting early osseointegration","volume":"40","author":"Al-Hezaimi K","year":"2014","unstructured":"Al-Hezaimi K, Nevins M, Kim SW, Fateh A, Kim DM. Efficacy of growth factor in promoting early osseointegration. J Oral Implantol. 2014, 40:543-8. 10.1563\/aaid-joi-D-13-00304","journal-title":"J Oral Implantol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.07.009","article-title":"Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features","volume":"101","author":"Dohan DM","year":"2006","unstructured":"Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006, 101:e45-50. 10.1016\/j.tripleo.2005.07.009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2015\/12636.5788","article-title":"Effect of platelet rich fibrin (PRF) on peri-implant soft tissue and crestal bone in one-stage implant placement: a randomized controlled trial","volume":"9","author":"Boora P","year":"2015","unstructured":"Boora P, Rathee M, Bhoria M. Effect of platelet rich fibrin (PRF) on peri-implant soft tissue and crestal bone in one-stage implant placement: a randomized controlled trial. J Clin Diagn Res. 2015, 9:ZC18-21. 10.7860\/JCDR\/2015\/12636.5788","journal-title":"J Clin Diagn Res"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.04.020","article-title":"In vitro effects of Choukroun's PRF (platelet-rich fibrin) on human gingival fibroblasts, dermal prekeratinocytes, preadipocytes, and maxillofacial osteoblasts in primary cultures","volume":"108","author":"Dohan Ehrenfest DM","year":"2009","unstructured":"Dohan Ehrenfest DM, Diss A, Odin G, Doglioli P, Hippolyte MP, Charrier JB. In vitro effects of Choukroun's PRF (platelet-rich fibrin) on human gingival fibroblasts, dermal prekeratinocytes, preadipocytes, and maxillofacial osteoblasts in primary cultures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009, 108:341-52. 10.1016\/j.tripleo.2009.04.020","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.07.008","article-title":"Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution","volume":"101","author":"Dohan DM","year":"2006","unstructured":"Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006, 101:e37-44. 10.1016\/j.tripleo.2005.07.008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0377-1237(09)80091-9","article-title":"Comparison of crestal bone loss along two implant crest module designs","volume":"65","author":"Goswami MM","year":"2009","unstructured":"Goswami MM. Comparison of crestal bone loss along two implant crest module designs. Med J Armed Forces India. 2009, 65:319-22. 10.1016\/S0377-1237(09)80091-9","journal-title":"Med J Armed Forces India"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(84)90225-7","article-title":"The biologic response to the single-crystal sapphire endosteal dental implant: scanning electron microscopic observations","volume":"51","author":"McKinney RV Jr","year":"1984","unstructured":"McKinney RV Jr, Steflik DE, Koth DL. The biologic response to the single-crystal sapphire endosteal dental implant: scanning electron microscopic observations. J Prosthet Dent. 1984, 51:372-9. 10.1016\/0022-3913(84)90225-7","journal-title":"J Prosthet Dent"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.12.995","article-title":"The effect of the distance from the contact point to the crest of bone on the presence or absence of the interproximal dental papilla","volume":"63","author":"Tarnow DP","year":"1992","unstructured":"Tarnow DP, Magner AW, Fletcher P. The effect of the distance from the contact point to the crest of bone on the presence or absence of the interproximal dental papilla. J Periodontol. 1992, 63:995-6. 10.1902\/jop.1992.63.12.995","journal-title":"J Periodontol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jds.2012.10.010","article-title":"Comparative evaluation of platelet-rich fibrin membrane and connective tissue graft in the treatment of multiple adjacent recession defects: a clinical study","volume":"10","author":"Uraz A","year":"2015","unstructured":"Uraz A, Sezgin Y, Yalim M, Taner IL, Cetiner D. Comparative evaluation of platelet-rich fibrin membrane and connective tissue graft in the treatment of multiple adjacent recession defects: a clinical study. J Dent Sci. 2015, 10:36-45. 10.1016\/j.jds.2012.10.010","journal-title":"J Dent Sci"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jobcr.2014.03.003","article-title":"Platelet rich fibrin: a new covering material for oral mucosal defects","volume":"4","author":"Mohanty S","year":"2014","unstructured":"Mohanty S, Pathak H, Dabas J. Platelet rich fibrin: a new covering material for oral mucosal defects. J Oral Biol Craniofac Res. 2014, 4:144-6. 10.1016\/j.jobcr.2014.03.003","journal-title":"J Oral Biol Craniofac Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01306.x","article-title":"A 10-year prospective study of ITI dental implants placed in the posterior region. I: Clinical and radiographic results","volume":"18","author":"Blanes RJ","year":"2007","unstructured":"Blanes RJ, Bernard JP, Blanes ZM, Belser UC. A 10-year prospective study of ITI dental implants placed in the posterior region. I: Clinical and radiographic results. Clin Oral Implants Res. 2007, 18:699-706. 10.1111\/j.1600-0501.2006.01306.x","journal-title":"Clin Oral Implants Res"},{"key":"ref19","article-title":"Osseointegrated implants in the treatment of partially edentulous jaws: a prospective 5-year multicenter study","volume":"9","author":"Lekholm U","year":"1994","unstructured":"Lekholm U, van Steenberghe D, Herrmann I, et al.. Osseointegrated implants in the treatment of partially edentulous jaws: a prospective 5-year multicenter study. Int J Oral Maxillofac Implants. 1994, 9:627-35.","journal-title":"Int J Oral Maxillofac Implants"},{"key":"ref20","article-title":"The effect of plaque on peri implant soft tissue health: a 4 years follow up study","volume":"3","author":"Rismanchian M","year":"2006","unstructured":"Rismanchian M, Fazel A. The effect of plaque on peri implant soft tissue health: a 4 years follow up study. Dent Res J. 2006, 3:1-6.","journal-title":"Dent Res J"},{"key":"ref21","article-title":"Regeneration of gingival papillae after single-implant treatment","volume":"17","author":"Jemt T","year":"1997","unstructured":"Jemt T. Regeneration of gingival papillae after single-implant treatment. Int J Periodontics Restorative Dent. 1997, 17:326-33.","journal-title":"Int J Periodontics Restorative Dent"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s10006-002-0367-6","article-title":"Growth stimulation of human osteoblast-like cells by thrombocyte concentrates in vitro. (Article in German)","volume":"6","author":"Weibrich G","year":"2002","unstructured":"Weibrich G, Gnoth SH, Otto M, Reichert TE, Wagner W. Growth stimulation of human osteoblast-like cells by thrombocyte concentrates in vitro. (Article in German). Mund Kiefer Gesichtschir. 2002, 6:168-74. 10.1007\/s10006-002-0367-6","journal-title":"Mund Kiefer Gesichtschir"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-4931(02)00321-1","article-title":"Investigation of cell reactions to microstructured implant surfaces","volume":"23","author":"Scheideler L","year":"2003","unstructured":"Scheideler L, Geis-Gerstorfer J, Kern D, Pfeiffer F, Rupp F, Weber H, Wolburg H. Investigation of cell reactions to microstructured implant surfaces. Mater Sci Eng C. 2003, 23:455-9. 10.1016\/S0928-4931(02)00321-1","journal-title":"Mater Sci Eng C"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0501.1994.050401.x","article-title":"Histologic probe penetration in healthy and inflamed peri-implant tissues","volume":"5","author":"Lang NP","year":"1994","unstructured":"Lang NP, Wetzel AC, Stich H, Caffesse RG. Histologic probe penetration in healthy and inflamed peri-implant tissues. Clin Oral Implants Res. 1994, 5:191-201. 10.1034\/j.1600-0501.1994.050401.x","journal-title":"Clin Oral Implants Res"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jds.2011.03.004","article-title":"Clinical and histologic evaluations of healing in an extraction socket filled with platelet-rich fibrin","volume":"6","author":"Zhao JH","year":"2011","unstructured":"Zhao JH, Tsai CH, Chang YC. Clinical and histologic evaluations of healing in an extraction socket filled with platelet-rich fibrin. J Dent Sci. 2011, 6:116-22. 10.1016\/j.jds.2011.03.004","journal-title":"J Dent Sci"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/125766-a-comparative-evaluation-of-soft-and-hard-tissue-changes-around-dental-implants-placed-with-and-without-platelet-rich-fibrin","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:59:24Z","timestamp":1707508764000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/125766-a-comparative-evaluation-of-soft-and-hard-tissue-changes-around-dental-implants-placed-with-and-without-platelet-rich-fibrin"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,30]]},"references-count":25,"URL":"https:\/\/doi.org\/10.7759\/cureus.36908","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3,30]]}}}