{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T07:32:05Z","timestamp":1750404725167},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,16]]},"DOI":"10.7759\/cureus.37635","type":"journal-article","created":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T12:45:50Z","timestamp":1681649150000},"source":"Crossref","is-referenced-by-count":2,"title":["A Rare Manifestation of Unknown Hyperparathyroidism as a Perforated Peptic Ulcer"],"prefix":"10.7759","author":[{"given":"Gideon","family":"Mlawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahid","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabeen","family":"Azhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Furhana","family":"Hussein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bashir","family":"Mahamud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulrahman","family":"Nugod","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7762\/cnr.2015.4.1.1","article-title":"The role of calcium in human aging","volume":"4","author":"Beto JA","year":"2015","unstructured":"Beto JA. The role of calcium in human aging. Clin Nutr Res. 2015, 4:1-8. 10.7762\/cnr.2015.4.1.1","journal-title":"Clin Nutr Res"},{"key":"ref2","article-title":"Calcium and its role in human body","volume":"4","author":"Pravina P","year":"2013","unstructured":"Pravina P, Sayaji D, Avinash M. Calcium and its role in human body. Int J Res Pharm Biomed Sci. 2013, 4:659-68.","journal-title":"Int J Res Pharm Biomed Sci"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2011.07.001","article-title":"Disorders of calcium metabolism and parathyroid disease","volume":"25","author":"Cooper MS","year":"2011","unstructured":"Cooper MS. Disorders of calcium metabolism and parathyroid disease. Best Pract Res Clin Endocrinol Metab. 2011, 25:975-83. 10.1016\/j.beem.2011.07.001","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref4","unstructured":"Management of hypercalcaemia. (2023). Accessed. January 24, 2023: https:\/\/handbook.ggcmedicines.org.uk\/guidelines\/electrolyte-disturbances\/management-of-hypercalcaemia\/."},{"key":"ref5","article-title":"Resistant hypercalcemia","author":"Omotosho YB","year":"2022","unstructured":"Omotosho YB, Zahra F. Resistant hypercalcemia. StatPearls (Internet). StatPearls Publishing, Treasure Island, FL; 2022."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/2042018810390260","article-title":"Endocrine and metabolic emergencies: hypercalcaemia","volume":"1","author":"Carroll R","year":"2010","unstructured":"Carroll R, Matfin G. Endocrine and metabolic emergencies: hypercalcaemia. Ther Adv Endocrinol Metab. 2010, 1:225-34. 10.1177\/2042018810390260","journal-title":"Ther Adv Endocrinol Metab"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/893134","article-title":"Multifactorial hypercalcemia and literature review on primary hyperparathyroidism associated with lymphoma","volume":"2014","author":"Maletkovic J","year":"2014","unstructured":"Maletkovic J, Isorena JP, Palma Diaz MF, Korenman SG, Yeh MW. Multifactorial hypercalcemia and literature review on primary hyperparathyroidism associated with lymphoma. Case Rep Endocrinol. 2014, 2014:893134. 10.1155\/2014\/893134","journal-title":"Case Rep Endocrinol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/1947-2714.170600","article-title":"Hypercalcemia of malignancy: an update on pathogenesis and management","volume":"7","author":"Mirrakhimov AE","year":"2015","unstructured":"Mirrakhimov AE. Hypercalcemia of malignancy: an update on pathogenesis and management. N Am J Med Sci. 2015, 7:483-93. 10.4103\/1947-2714.170600","journal-title":"N Am J Med Sci"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.13-3-287","article-title":"How to approach hypercalcaemia","volume":"13","author":"Crowley R","year":"2013","unstructured":"Crowley R, Gittoes N. How to approach hypercalcaemia. Clin Med (Lond). 2013, 13:287-90. 10.7861\/clinmedicine.13-3-287","journal-title":"Clin Med (Lond)"},{"key":"ref10","unstructured":"Assessment of hypercalcaemia. (2022). Accessed. January 15, 2023: https:\/\/bestpractice.bmj.com\/topics\/en-gb\/159."},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.4989","article-title":"Stones, bones, groans, and psychic moans: primary hyperparathyroidism presenting as surgical emergency","volume":"11","author":"Saleem M","year":"2019","unstructured":"Saleem M, Iftikhar H. Stones, bones, groans, and psychic moans: primary hyperparathyroidism presenting as surgical emergency. Cureus. 2019, 11:e4989. 10.7759\/cureus.4989","journal-title":"Cureus"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000104224","article-title":"Peptic ulcer perforation as the first manifestation of previously unknown primary hyperparathyroidism","volume":"1","author":"Efremidou EI","year":"2007","unstructured":"Efremidou EI, Liratzopoulos N, Papageorgiou MS, Karanikas M, Pavlidou E, Romanidis K, Manolas KJ. Peptic ulcer perforation as the first manifestation of previously unknown primary hyperparathyroidism. Case Rep Gastroenterol. 2007, 1:21-6. 10.1159\/000104224","journal-title":"Case Rep Gastroenterol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v9.i1.1","article-title":"Perforated peptic ulcer-an update","volume":"9","author":"Chung KT","year":"2017","unstructured":"Chung KT, Shelat VG. Perforated peptic ulcer-an update. World J Gastrointest Surg. 2017, 9:1-12. 10.4240\/wjgs.v9.i1.1","journal-title":"World J Gastrointest Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2017.104","article-title":"Primary hyperparathyroidism","volume":"14","author":"Walker MD","year":"2018","unstructured":"Walker MD, Silverberg SJ. Primary hyperparathyroidism. Nat Rev Endocrinol. 2018, 14:115-25. 10.1038\/nrendo.2017.104","journal-title":"Nat Rev Endocrinol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1530\/EDM-17-0059","article-title":"Two rare manifestations of primary hyperparathyroidism: paralysis and peptic ulcer bleeding","volume":"2017","author":"Heidarpour M","year":"2017","unstructured":"Heidarpour M, Karami M, Hedayat P, Aminorroaya A. Two rare manifestations of primary hyperparathyroidism: paralysis and peptic ulcer bleeding. Endocrinol Diabetes Metab Case Rep. 2017, 2017:17-0059. 10.1530\/EDM-17-0059","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.5003","article-title":"A rare case of acetaminophen toxicity leading to severe kidney injury","volume":"11","author":"Saleem M","year":"2019","unstructured":"Saleem M, Iftikhar H. A rare case of acetaminophen toxicity leading to severe kidney injury. Cureus. 2019, 11:e5003. 10.7759\/cureus.5003","journal-title":"Cureus"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-240570","article-title":"Perforated gastric ulcer as the initial manifestation of hyperparathyroidism","volume":"14","author":"Castle C","year":"2021","unstructured":"Castle C, Tietjens J. Perforated gastric ulcer as the initial manifestation of hyperparathyroidism. BMJ Case Rep. 2021, 14:e240570. 10.1136\/bcr-2020-240570","journal-title":"BMJ Case Rep"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i20.3229","article-title":"Role of calcium and other trace elements in the gastrointestinal physiology","volume":"12","author":"Kirchhoff P","year":"2006","unstructured":"Kirchhoff P, Geibel JP. Role of calcium and other trace elements in the gastrointestinal physiology. World J Gastroenterol. 2006, 12:3229-36. 10.3748\/wjg.v12.i20.3229","journal-title":"World J Gastroenterol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M107315200","article-title":"The stomach divalent ion-sensing receptor scar is a modulator of gastric acid secretion","volume":"276","author":"Geibel JP","year":"2001","unstructured":"Geibel JP, Wagner CA, Caroppo R, et al.. The stomach divalent ion-sensing receptor scar is a modulator of gastric acid secretion. J Biol Chem. 2001, 276:39549-52. 10.1074\/jbc.M107315200","journal-title":"J Biol Chem"},{"key":"ref20","article-title":"Primary hyperparathyroidism and peptic ulcer","volume":"80","author":"Gasparoni P","year":"1989","unstructured":"Gasparoni P, Caroli A, Sardeo G, Maschio S, Lo Giudice C, Fioretti D. Primary hyperparathyroidism and peptic ulcer. Minerva Med. 1989, 80:1327-30.","journal-title":"Minerva Med"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198904133201504","article-title":"A randomized trial of nonoperative treatment for perforated peptic ulcer","volume":"320","author":"Crofts TJ","year":"1989","unstructured":"Crofts TJ, Park KG, Steele RJ, Chung SS, Li AK. A randomized trial of nonoperative treatment for perforated peptic ulcer. N Engl J Med. 1989, 320:970-3. 10.1056\/NEJM198904133201504","journal-title":"N Engl J Med"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2007.11796","article-title":"Results of conservative treatment for perforated gastroduodenal ulcers in patients not eligible for surgical repair","volume":"137","author":"Bucher P","year":"2007","unstructured":"Bucher P, Oulhaci W, Morel P, Ris F, Huber O. Results of conservative treatment for perforated gastroduodenal ulcers in patients not eligible for surgical repair. Swiss Med Wkly. 2007, 137:337-40. 10.4414\/smw.2007.11796","journal-title":"Swiss Med Wkly"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/150112-a-rare-manifestation-of-unknown-hyperparathyroidism-as-a-perforated-peptic-ulcer","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:58:52Z","timestamp":1707508732000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/150112-a-rare-manifestation-of-unknown-hyperparathyroidism-as-a-perforated-peptic-ulcer"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,16]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.37635","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4,16]]}}}