{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T00:29:59Z","timestamp":1707524999687},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,20]]},"DOI":"10.7759\/cureus.37868","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T13:17:08Z","timestamp":1681996628000},"source":"Crossref","is-referenced-by-count":0,"title":["Low Bone Mass and Recurrent Fractures in Neurofibromatosis With Concomitant Hemoglobin Sickle Cell (SC) Disease"],"prefix":"10.7759","author":[{"given":"Hussam","family":"Alkaissi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beisi","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parima","family":"Saxena","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Navid","family":"Salahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Muthu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samy I.","family":"McFarlane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathmechdis-012418-012838","article-title":"Pathophysiology of sickle cell disease","volume":"14","author":"Sundd P","year":"2019","unstructured":"Sundd P, Gladwin MT, Novelli EM. Pathophysiology of sickle cell disease. Annu Rev Pathol. 2019, 14:263-92. 10.1146\/annurev-pathmechdis-012418-012838","journal-title":"Annu Rev Pathol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18041832","article-title":"Mechanisms of bone impairment in sickle bone disease","volume":"18","author":"Giordano P","year":"2021","unstructured":"Giordano P, Urbano F, Lassandro G, Faienza MF. Mechanisms of bone impairment in sickle bone disease. Int J Environ Res Public Health. 2021, 18:1832. 10.3390\/ijerph18041832","journal-title":"Int J Environ Res Public Health"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3204","article-title":"Neurofibromatosis type 1 revisited","volume":"123","author":"Williams VC","year":"2009","unstructured":"Williams VC, Lucas J, Babcock MA, Gutmann DH, Korf B, Maria BL. Neurofibromatosis type 1 revisited. Pediatrics. 2009, 123:124-33. 10.1542\/peds.2007-3204","journal-title":"Pediatrics"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11020444","article-title":"Current aspects on the pathophysiology of bone metabolic defects during progression of scoliosis in neurofibromatosis type 1","volume":"11","author":"Kaspiris A","year":"2022","unstructured":"Kaspiris A, Savvidou OD, Vasiliadis ES, et al.. Current aspects on the pathophysiology of bone metabolic defects during progression of scoliosis in neurofibromatosis type 1. J Clin Med. 2022, 11:444. 10.3390\/jcm11020444","journal-title":"J Clin Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.06487.x","article-title":"Bone mass density in adults with sickle cell disease","volume":"136","author":"Sarrai M","year":"2007","unstructured":"Sarrai M, Duroseau H, D'Augustine J, Moktan S, Bellevue R. Bone mass density in adults with sickle cell disease. Br J Haematol. 2007, 136:666-72. 10.1111\/j.1365-2141.2006.06487.x","journal-title":"Br J Haematol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2021.07.002","article-title":"Metabolic bone diseases in sickle cell anemia patients and evaluation of associated factors","volume":"363","author":"Eskiocak \u00d6","year":"2022","unstructured":"Eskiocak \u00d6, Y\u0131lmaz M\u00d6, \u0130lhan G. Metabolic bone diseases in sickle cell anemia patients and evaluation of associated factors. Am J Med Sci. 2022, 363:490-4. 10.1016\/j.amjms.2021.07.002","journal-title":"Am J Med Sci"},{"key":"ref7","article-title":"Prevalence of vitamin D deficiency in adults with sickle cell disease","volume":"102","author":"Goodman BM","year":"2010","unstructured":"Goodman BM, Artz N, Radford B, Chen IA. Prevalence of vitamin D deficiency in adults with sickle cell disease. J Natl Med Assoc. 2010, 102:332-5.","journal-title":"J Natl Med Assoc"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3263951","article-title":"Amelioration of sickle cell pain after parathyroidectomy in two patients with concurrent hyperparathyroidism: an interesting finding","volume":"2016","author":"Muthu J","year":"2016","unstructured":"Muthu J, Ali M. Amelioration of sickle cell pain after parathyroidectomy in two patients with concurrent hyperparathyroidism: an interesting finding. Case Rep Med. 2016, 2016:3263951. 10.1155\/2016\/3263951","journal-title":"Case Rep Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.1078853","article-title":"Mineral bone disorders and kidney disease in hospitalized children with sickle cell anemia","volume":"10","author":"Batte A","year":"2022","unstructured":"Batte A, Kasirye P, Baluku R, et al.. Mineral bone disorders and kidney disease in hospitalized children with sickle cell anemia. Front Pediatr. 2022, 10:1078853. 10.3389\/fped.2022.1078853","journal-title":"Front Pediatr"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-009-0933-y","article-title":"High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1","volume":"21","author":"Seitz S","year":"2010","unstructured":"Seitz S, Schnabel C, Busse B, et al.. High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1. Osteoporos Int. 2010, 21:119-27. 10.1007\/s00198-009-0933-y","journal-title":"Osteoporos Int"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29092","article-title":"Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions","volume":"116","author":"Yang FC","year":"2006","unstructured":"Yang FC, Chen S, Robling AG, et al.. Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions. J Clin Invest. 2006, 116:2880-91. 10.1172\/JCI29092","journal-title":"J Clin Invest"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1992","article-title":"Hyperactive transforming growth factor-\u03b21 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model","volume":"28","author":"Rhodes SD","year":"2013","unstructured":"Rhodes SD, Wu X, He Y, et al.. Hyperactive transforming growth factor-\u03b21 signaling potentiates skeletal defects in a neurofibromatosis type 1 mouse model. J Bone Miner Res. 2013, 28:2476-89. 10.1002\/jbmr.1992","journal-title":"J Bone Miner Res"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2011.12.011","article-title":"Osteoclasts derived from patients with neurofibromatosis 1 (NF1) display insensitivity to bisphosphonates in vitro","volume":"50","author":"Heerv\u00e4 E","year":"2012","unstructured":"Heerv\u00e4 E, Peltonen S, Svedstr\u00f6m E, Aro HT, V\u00e4\u00e4n\u00e4nen K, Peltonen J. Osteoclasts derived from patients with neurofibromatosis 1 (NF1) display insensitivity to bisphosphonates in vitro. Bone. 2012, 50:798-803. 10.1016\/j.bone.2011.12.011","journal-title":"Bone"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-013-9835-2","article-title":"Follow-up of six patients with neurofibromatosis 1-related osteoporosis treated with alendronate for 23 months","volume":"94","author":"Heerv\u00e4 E","year":"2014","unstructured":"Heerv\u00e4 E, Huilaja L, Leinonen P, Peltonen S, Peltonen J. Follow-up of six patients with neurofibromatosis 1-related osteoporosis treated with alendronate for 23 months. Calcif Tissue Int. 2014, 94:608-12. 10.1007\/s00223-013-9835-2","journal-title":"Calcif Tissue Int"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2007.12.004","article-title":"Generalized metabolic bone disease in neurofibromatosis type I","volume":"94","author":"Brunetti-Pierri N","year":"2008","unstructured":"Brunetti-Pierri N, Doty SB, Hicks J, et al.. Generalized metabolic bone disease in neurofibromatosis type I. Mol Genet Metab. 2008, 94:105-11. 10.1016\/j.ymgme.2007.12.004","journal-title":"Mol Genet Metab"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000002647","article-title":"A rare report of the coexistence of sickle cell disease, neurofibromatosis type 1, and intracranial hypertension in a pediatric patient","volume":"45","author":"Patel A","year":"2023","unstructured":"Patel A, Winter T, Jain A. A rare report of the coexistence of sickle cell disease, neurofibromatosis type 1, and intracranial hypertension in a pediatric patient. J Pediatr Hematol Oncol. 2023, 45:155-8. 10.1097\/MPH.0000000000002647","journal-title":"J Pediatr Hematol Oncol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/151991-low-bone-mass-and-recurrent-fractures-in-neurofibromatosis-with-concomitant-hemoglobin-sickle-cell-sc-disease","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:59:52Z","timestamp":1707508792000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/151991-low-bone-mass-and-recurrent-fractures-in-neurofibromatosis-with-concomitant-hemoglobin-sickle-cell-sc-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,20]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.37868","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4,20]]}}}