{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:20:26Z","timestamp":1791930026899,"version":"4.3.4"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,29]]},"DOI":"10.7759\/cureus.39655","type":"journal-article","created":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T19:31:16Z","timestamp":1685388676000},"source":"Crossref","is-referenced-by-count":2,"title":["Pituitary Macroadenoma Secondary to Congenital Hypothyroidism With Growth Failure and Developmental Delay: A Rare Presentation"],"prefix":"10.7759","author":[{"given":"Sham","family":"Lohiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitturi","family":"Venkata Sai Akhil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubhangi Patil","family":"Ganvir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richa","family":"Chaudhary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayant","family":"Vagha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198803103181003","article-title":"Long-term growth in juvenile acquired hypothyroidism: the failure to achieve normal adult stature","volume":"318","author":"Rivkees SA","year":"1988","unstructured":"Rivkees SA, Bode HH, Crawford JD. Long-term growth in juvenile acquired hypothyroidism: the failure to achieve normal adult stature. N Engl J Med. 1988, 318:599-602. 10.1056\/NEJM198803103181003","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4158\/EP.12.1.29","article-title":"Pituitary enlargement in patients with primary hypothyroidism","volume":"12","author":"Khawaja NM","year":"2006","unstructured":"Khawaja NM, Taher BM, Barham ME, et al.. Pituitary enlargement in patients with primary hypothyroidism. Endocr Pract. 2006, 12:29-34. 10.4158\/EP.12.1.29","journal-title":"Endocr Pract"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1515\/jpem.2001.14.9.1665","article-title":"Pituitary pseudotumor with unusual presentation reversed shortly after the introduction of thyroxine replacement therapy","volume":"14","author":"Kocova M","year":"2001","unstructured":"Kocova M, Netkov S, Sukarova-Angelovska E. Pituitary pseudotumor with unusual presentation reversed shortly after the introduction of thyroxine replacement therapy. J Pediatr Endocrinol Metab. 2001, 14:1665-9. 10.1515\/jpem.2001.14.9.1665","journal-title":"J Pediatr Endocrinol Metab"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1017\/s0317167100027153","article-title":"Primary hypothyroidism presenting as growth delay and pituitary enlargement","volume":"15","author":"Farley JD","year":"1988","unstructured":"Farley JD, Toth EL, Ryan EA. Primary hypothyroidism presenting as growth delay and pituitary enlargement. Can J Neurol Sci. 1988, 15:35-7. 10.1017\/s0317167100027153","journal-title":"Can J Neurol Sci"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159\/000181287","article-title":"Pituitary gland enlargement in primary hypothyroidism: a report of 5 cases with follow-up data","volume":"32","author":"Ahmed M","year":"1989","unstructured":"Ahmed M, Banna M, Sakati N, Woodhouse N. Pituitary gland enlargement in primary hypothyroidism: a report of 5 cases with follow-up data. Horm Res. 1989, 32:188-92. 10.1159\/000181287","journal-title":"Horm Res"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1996.02170310057010","article-title":"Pituitary enlargement on magnetic resonance imaging in congenital hypothyroidism","volume":"150","author":"Desai MP","year":"1996","unstructured":"Desai MP, Mehta RU, Choksi CS, Colaco MP. Pituitary enlargement on magnetic resonance imaging in congenital hypothyroidism. Arch Pediatr Adolesc Med. 1996, 150:623-8. 10.1001\/archpedi.1996.02170310057010","journal-title":"Arch Pediatr Adolesc Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1515\/jpem.2011.310","article-title":"Does clinical management impact height potential in children with severe acquired hypothyroidism?","volume":"24","author":"Nebesio TD","year":"2011","unstructured":"Nebesio TD, Wise MD, Perkins SM, Eugster EA. Does clinical management impact height potential in children with severe acquired hypothyroidism?. J Pediatr Endocrinol Metab. 2011, 24:893-6. 10.1515\/jpem.2011.310","journal-title":"J Pediatr Endocrinol Metab"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3171\/ped.2005.102.4.0413","article-title":"Primary hypothyroidism in a 12-year-old girl with a suprasellar pituitary mass: rapid regression after thyroid replacement therapy: case report","volume":"102","author":"Ashley WW Jr","year":"2005","unstructured":"Ashley WW Jr, Ojemann JG, Park TS, Wippold FJ 2nd. Primary hypothyroidism in a 12-year-old girl with a suprasellar pituitary mass: rapid regression after thyroid replacement therapy: case report. J Neurosurg. 2005, 102:413-6. 10.3171\/ped.2005.102.4.0413","journal-title":"J Neurosurg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000028649","article-title":"Primary hypothyroidism mimicking a pituitary macroadenoma","volume":"28","author":"Ehirim PU","year":"1998","unstructured":"Ehirim PU, Kerr DS, Cohen AR. Primary hypothyroidism mimicking a pituitary macroadenoma. Pediatr Neurosurg. 1998, 28:195-7. 10.1159\/000028649","journal-title":"Pediatr Neurosurg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/000456320103800518","article-title":"Autoimmune hypothyroidism coexisting with a pituitary adenoma secreting thyroid-stimulating hormone, prolactin and alpha-subunit","volume":"38","author":"Idiculla JM","year":"2001","unstructured":"Idiculla JM, Beckett G, Statham PF, Ironside JW, Atkin SL, Patrick AW. Autoimmune hypothyroidism coexisting with a pituitary adenoma secreting thyroid-stimulating hormone, prolactin and alpha-subunit. Ann Clin Biochem. 2001, 38:566-71. 10.1177\/000456320103800518","journal-title":"Ann Clin Biochem"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000070827","article-title":"Empty sella following spontaneous resolution of a pituitary macroadenoma","volume":"60","author":"Weiss RE","year":"2003","unstructured":"Weiss RE. Empty sella following spontaneous resolution of a pituitary macroadenoma. Horm Res. 2003, 60:49-52. 10.1159\/000070827","journal-title":"Horm Res"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12201","article-title":"Reactive pituitary hyperplasia associated with paediatric primary hypothyroidism","volume":"49","author":"Mills NJ","year":"2013","unstructured":"Mills NJ, Wong SC, Sabin MA, Hewitt JK. Reactive pituitary hyperplasia associated with paediatric primary hypothyroidism. J Paediatr Child Health. 2013, 49:421-2. 10.1111\/jpc.12201","journal-title":"J Paediatr Child Health"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-008-1012-9","article-title":"Primary hypothyroidism mimicking a pituitary macroadenoma: regression after thyroid hormone replacement therapy","volume":"39","author":"Eom KS","year":"2009","unstructured":"Eom KS, See-Sung C, Kim JD, Kim JM, Kim TY. Primary hypothyroidism mimicking a pituitary macroadenoma: regression after thyroid hormone replacement therapy. Pediatr Radiol. 2009, 39:164-7. 10.1007\/s00247-008-1012-9","journal-title":"Pediatr Radiol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-013-1221-6","article-title":"Autoimmune hypothyroidism presenting as pituitary hyperplasia","volume":"81","author":"Namburi RP","year":"2014","unstructured":"Namburi RP, Karthik TS, Ponnala AR. Autoimmune hypothyroidism presenting as pituitary hyperplasia. Indian J Pediatr. 2014, 81:937-9. 10.1007\/s12098-013-1221-6","journal-title":"Indian J Pediatr"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2017.06.007","article-title":"Pituitary hyperplasia due to primary hypothyroidism. (Article in French)","volume":"38","author":"Ammar M","year":"2017","unstructured":"Ammar M, HadjKacem F, Maalej A, Abid G, Charfi N, Abid M. Pituitary hyperplasia due to primary hypothyroidism. (Article in French). Rev Med Interne. 2017, 38:844-6. 10.1016\/j.revmed.2017.06.007","journal-title":"Rev Med Interne"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050087","article-title":"MR imaging of pituitary hyperplasia in a child with growth arrest and primary hypothyroidism","volume":"10","author":"Papakonstantinou O","year":"2000","unstructured":"Papakonstantinou O, Bitsori M, Mamoulakis D, Bakantaki A, Papadaki E, Gourtsoyiannis N. MR imaging of pituitary hyperplasia in a child with growth arrest and primary hypothyroidism. Eur Radiol. 2000, 10:516-8. 10.1007\/s003300050087","journal-title":"Eur Radiol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1053\/crad.2002.1119","article-title":"MRI in the differential diagnosis of a sellar mass","volume":"58","author":"Connor SE","year":"2003","unstructured":"Connor SE, Penney CC. MRI in the differential diagnosis of a sellar mass. Clin Radiol. 2003, 58:20-31. 10.1053\/crad.2002.1119","journal-title":"Clin Radiol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/124757-pituitary-macroadenoma-secondary-to-congenital-hypothyroidism-with-growth-failure-and-developmental-delay-a-rare-presentation","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:03:48Z","timestamp":1707509028000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/124757-pituitary-macroadenoma-secondary-to-congenital-hypothyroidism-with-growth-failure-and-developmental-delay-a-rare-presentation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,29]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.39655","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5,29]]}}}