{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T01:30:08Z","timestamp":1773970208662,"version":"3.50.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,4]]},"DOI":"10.7759\/cureus.39954","type":"journal-article","created":{"date-parts":[[2023,6,5]],"date-time":"2023-06-05T03:49:08Z","timestamp":1685936948000},"source":"Crossref","is-referenced-by-count":4,"title":["The Efficacy of Denosumab in Treating Spinal Aneurysmal Bone Cyst: A Case Report"],"prefix":"10.7759","author":[{"given":"Shinji","family":"Kotaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Ota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Manabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199803010-00018","article-title":"Aneurysmal bone cyst of the spine. Management and outcome","volume":"23","author":"Papagelopoulos PJ","year":"1998","unstructured":"Papagelopoulos PJ, Currier BL, Shaughnessy WJ, Sim FH, Ebsersold MJ, Bond JR, Unni KK. Aneurysmal bone cyst of the spine. Management and outcome. Spine (Phila Pa 1976). 1998, 23:621-8. 10.1097\/00007632-199803010-00018","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-016-9371-6","article-title":"Current management of aneurysmal bone cysts","volume":"9","author":"Park HY","year":"2016","unstructured":"Park HY, Yang SK, Sheppard WL, et al.. Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med. 2016, 9:435-44. 10.1007\/s12178-016-9371-6","journal-title":"Curr Rev Musculoskelet Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920615)69:12<2921::aid-cncr2820691210>3.0.co;2-e","article-title":"Aneurysmal bone cyst. A clinicopathologic study of 238 cases","volume":"69","author":"Vergel De Dios AM","year":"1992","unstructured":"Vergel De Dios AM, Bond JR, Shives TC, McLeod RA, Unni KK. Aneurysmal bone cyst. A clinicopathologic study of 238 cases. Cancer. 1992, 69:2921-31. 10.1002\/1097-0142(19920615)69:12&lt;2921::aid-cncr2820691210&gt;3.0.co;2-e","journal-title":"Cancer"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2022.03.040","article-title":"Aneurysmal bone cyst of the spine in adult patients: a systematic review and comparison of primary vs secondary lesions","volume":"100","author":"Palmisciano P","year":"2022","unstructured":"Palmisciano P, Hunter M, Lokesh N, et al.. Aneurysmal bone cyst of the spine in adult patients: a systematic review and comparison of primary vs secondary lesions. J Clin Neurosci. 2022, 100:15-22. 10.1016\/j.jocn.2022.03.040","journal-title":"J Clin Neurosci"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001350","article-title":"Interest of denosumab for the treatment of giant-cells tumors and aneurysmal bone cysts of the spine. About nine cases","volume":"41","author":"Dubory A","year":"2016","unstructured":"Dubory A, Missenard G, Domont J, Court C. Interest of denosumab for the treatment of giant-cells tumors and aneurysmal bone cysts of the spine. About nine cases. Spine (Phila Pa 1976). 2016, 41:E654-60. 10.1097\/BRS.0000000000001350","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1302\/2633-1462.22.BJO-2020-0168","article-title":"Efficacy of treatment interventions for primary aneurysmal bone cysts: a systematic review","volume":"2","author":"Bavan L","year":"2021","unstructured":"Bavan L, Wijendra A, Kothari A. Efficacy of treatment interventions for primary aneurysmal bone cysts: a systematic review. Bone Jt Open. 2021, 2:125-33. 10.1302\/2633-1462.22.BJO-2020-0168","journal-title":"Bone Jt Open"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.26926","article-title":"Denosumab treatment in aneurysmal bone cyst: evaluation of nine cases","volume":"65","author":"Kurucu N","year":"2018","unstructured":"Kurucu N, Akyuz C, Ergen FB, et al.. Denosumab treatment in aneurysmal bone cyst: evaluation of nine cases. Pediatr Blood Cancer. 2018, 65:10.1002\/pbc.26926","journal-title":"Pediatr Blood Cancer"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e328354c129","article-title":"RANKL, denosumab, and giant cell tumor of bone","volume":"24","author":"Thomas DM","year":"2012","unstructured":"Thomas DM. RANKL, denosumab, and giant cell tumor of bone. Curr Opin Oncol. 2012, 24:397-403. 10.1097\/CCO.0b013e328354c129","journal-title":"Curr Opin Oncol"},{"key":"ref9","article-title":"Denosumab: non-surgical treatment option for selective arterial embolization resistant aneurysmal bone cyst of the spine and sacrum. Case report","volume":"20","author":"Ghermandi R","year":"2016","unstructured":"Ghermandi R, Terzi S, Gasbarrini A, Boriani S. Denosumab: non-surgical treatment option for selective arterial embolization resistant aneurysmal bone cyst of the spine and sacrum. Case report. Eur Rev Med Pharmacol Sci. 2016, 20:3692-5.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-009-1137-z","article-title":"Morbidity of en bloc resections in the spine","volume":"19","author":"Boriani S","year":"2010","unstructured":"Boriani S, Bandiera S, Donthineni R, Amendola L, Cappuccio M, De Iure F, Gasbarrini A. Morbidity of en bloc resections in the spine. Eur Spine J. 2010, 19:231-41. 10.1007\/s00586-009-1137-z","journal-title":"Eur Spine J"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000208","article-title":"Radiation therapy for aneurysmal bone cysts","volume":"40","author":"Zhu S","year":"2017","unstructured":"Zhu S, Hitchcock KE, Mendenhall WM. Radiation therapy for aneurysmal bone cysts. Am J Clin Oncol. 2017, 40:621-4. 10.1097\/COC.0000000000000208","journal-title":"Am J Clin Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2566-7","article-title":"Aneurysmal bone cyst of the mobile spine: the therapeutic role of embolization","volume":"22","author":"Amendola L","year":"2013","unstructured":"Amendola L, Simonetti L, Simoes CE, Bandiera S, De Iure F, Boriani S. Aneurysmal bone cyst of the mobile spine: the therapeutic role of embolization. Eur Spine J. 2013, 22:533-41. 10.1007\/s00586-012-2566-7","journal-title":"Eur Spine J"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20120525-43","article-title":"Successful treatment of aggressive aneurysmal bone cyst of the pelvis with serial embolization","volume":"35","author":"Rossi G","year":"2012","unstructured":"Rossi G, Mavrogenis AF, Papagelopoulos PJ, Rimondi E, Ruggieri P. Successful treatment of aggressive aneurysmal bone cyst of the pelvis with serial embolization. Orthopedics. 2012, 35:e963-8. 10.3928\/01477447-20120525-43","journal-title":"Orthopedics"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-010912","article-title":"Percutaneous treatment of symptomatic aneurysmal bone cyst of L5 by percutaneous injection of osteoconductive material (Cerament)","volume":"2013","author":"Guarnieri G","year":"2013","unstructured":"Guarnieri G, Vassallo P, Muto M, Muto M. Percutaneous treatment of symptomatic aneurysmal bone cyst of L5 by percutaneous injection of osteoconductive material (Cerament). BMJ Case Rep. 2013, 2013:10.1136\/bcr-2013-010912","journal-title":"BMJ Case Rep"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-019-2855-y","article-title":"Aneurysmal bone cyst: results of an off label treatment with denosumab","volume":"20","author":"D\u00fcrr HR","year":"2019","unstructured":"D\u00fcrr HR, Grahneis F, Baur-Melnyk A, Kn\u00f6sel T, Birkenmaier C, Jansson V, Klein A. Aneurysmal bone cyst: results of an off label treatment with denosumab. BMC Musculoskelet Disord. 2019, 20:456. 10.1186\/s12891-019-2855-y","journal-title":"BMC Musculoskelet Disord"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2021.105260","article-title":"Denosumab in the management of aneurysmal bone cyst","volume":"89","author":"Maximen J","year":"2022","unstructured":"Maximen J, Robin F, Tronchot A, Rossetti A, Ropars M, Guggenbuhl P. Denosumab in the management of aneurysmal bone cyst. Joint Bone Spine. 2022, 89:105260. 10.1016\/j.jbspin.2021.105260","journal-title":"Joint Bone Spine"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/159125-the-efficacy-of-denosumab-in-treating-spinal-aneurysmal-bone-cyst-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:58:24Z","timestamp":1707508704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/159125-the-efficacy-of-denosumab-in-treating-spinal-aneurysmal-bone-cyst-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,4]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.39954","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6,4]]}}}