{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:42:20Z","timestamp":1790876540780,"version":"4.1.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,31]]},"DOI":"10.7759\/cureus.42713","type":"journal-article","created":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T07:12:00Z","timestamp":1690787520000},"source":"Crossref","is-referenced-by-count":4,"title":["Comparing the Effect of Phenylephrine Bolus and Phenylephrine Infusion for Maintaining Arterial Blood Pressure During Cesarean Delivery Under Spinal Anesthesia: A Randomized Prospective Study"],"prefix":"10.7759","author":[{"given":"Dheer","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay Brijesh Singh","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit K","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrityunjay K","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000602","article-title":"Norepinephrine for spinal hypotension during cesarean delivery: another paradigm shift?","volume":"122","author":"Carvalho B","year":"2015","unstructured":"Carvalho B, Dyer RA. Norepinephrine for spinal hypotension during cesarean delivery: another paradigm shift?. Anesthesiology. 2015, 122:728-30. 10.1097\/ALN.0000000000000602","journal-title":"Anesthesiology"},{"key":"ref2","article-title":"Maternal hypotension during spinal anesthesia for caesarean delivery","volume":"79","author":"Mercier FJ","year":"2013","unstructured":"Mercier FJ, Aug\u00e8 M, Hoffmann C, Fischer C, Le Gouez A. Maternal hypotension during spinal anesthesia for caesarean delivery. Minerva Anestesiol. 2013, 79:62-73.","journal-title":"Minerva Anestesiol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14268","article-title":"Randomised double-blind comparison of bolus phenylephrine or ephedrine for treatment of hypotension in women with pre-eclampsia undergoing caesarean section","volume":"73","author":"Mohta M","year":"2018","unstructured":"Mohta M, Duggal S, Chilkoti GT. Randomised double-blind comparison of bolus phenylephrine or ephedrine for treatment of hypotension in women with pre-eclampsia undergoing caesarean section. Anaesthesia. 2018, 73:839-46. 10.1111\/anae.14268","journal-title":"Anaesthesia"},{"key":"ref4","article-title":"Anesthesia for obstetrics","author":"Birnbach DJ","year":"2010","unstructured":"Birnbach DJ, Bateman BT. Anesthesia for obstetrics. Miller's Anesthesia. 7th ed. Miller RD (ed): Churchill Livingstone, Philadelphia; 2010. 4758."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.20471\/acc.2019.58.s1.13","article-title":"Spinal anaesthesia-induced hypotension in obstetrics: prevention and therapy","volume":"58","author":"\u0160klebar I","year":"2019","unstructured":"\u0160klebar I, Bujas T, Habek D. Spinal anaesthesia-induced hypotension in obstetrics: prevention and therapy. Acta Clin Croat. 2019, 58:90-5. 10.20471\/acc.2019.58.s1.13","journal-title":"Acta Clin Croat"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2017.01.001","article-title":"Spinal-induced hypotension: incidence, mechanisms, prophylaxis, and management: summarizing 20 years of research","volume":"31","author":"Lee JE","year":"2017","unstructured":"Lee JE, George RB, Habib AS. Spinal-induced hypotension: incidence, mechanisms, prophylaxis, and management: summarizing 20 years of research. Best Pract Res Clin Anaesthesiol. 2017, 31:57-68. 10.1016\/j.bpa.2017.01.001","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4103\/aer.AER_23_18","article-title":"Study comparing phenylephrine bolus and infusion for maternal hypotension and neonatal outcome during cesarean section under spinal anesthesia","volume":"12","author":"Choudhary M","year":"2018","unstructured":"Choudhary M, Bajaj JK. Study comparing phenylephrine bolus and infusion for maternal hypotension and neonatal outcome during cesarean section under spinal anesthesia. Anesth Essays Res. 2018, 12:446-51. 10.4103\/aer.AER_23_18","journal-title":"Anesth Essays Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200204000-00028","article-title":"A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery","volume":"94","author":"Lee A","year":"2002","unstructured":"Lee A, Ngan Kee WD, Gin T. A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg. 2002, 94:920-6. 10.1097\/00000539-200204000-00028","journal-title":"Anesth Analg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200212000-00034","article-title":"Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery","volume":"97","author":"Cooper DW","year":"2002","unstructured":"Cooper DW, Carpenter M, Mowbray P, Desira WR, Ryall DM, Kokri MS. Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Anesthesiology. 2002, 97:1582-90. 10.1097\/00000542-200212000-00034","journal-title":"Anesthesiology"},{"key":"ref10","article-title":"Review and update on inotropes and vasopressors","volume":"19","author":"Cooper BE","year":"2008","unstructured":"Cooper BE. Review and update on inotropes and vasopressors. AACN Adv Crit Care. 2008, 19:5-13.","journal-title":"AACN Adv Crit Care"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003704","article-title":"Comparison of intermittent intravenous boluses of phenylephrine and norepinephrine to prevent and treat spinal-induced hypotension in cesarean deliveries: randomized controlled trial","volume":"129","author":"Sharkey AM","year":"2019","unstructured":"Sharkey AM, Siddiqui N, Downey K, Ye XY, Guevara J, Carvalho JC. Comparison of intermittent intravenous boluses of phenylephrine and norepinephrine to prevent and treat spinal-induced hypotension in cesarean deliveries: randomized controlled trial. Anesth Analg. 2019, 129:1312-8. 10.1213\/ANE.0000000000003704","journal-title":"Anesth Analg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14950","article-title":"Prophylactic phenylephrine and fluid co-administration to reduce spinal hypotension during elective caesarean section in a resource-limited setting: a prospective alternating intervention study","volume":"75","author":"Buthelezi AS","year":"2020","unstructured":"Buthelezi AS, Bishop DG, Rodseth RN, Dyer RA. Prophylactic phenylephrine and fluid co-administration to reduce spinal hypotension during elective caesarean section in a resource-limited setting: a prospective alternating intervention study. Anaesthesia. 2020, 75:487-92. 10.1111\/anae.14950","journal-title":"Anaesthesia"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182373a3e","article-title":"A review of the impact of phenylephrine administration on maternal hemodynamics and maternal and neonatal outcomes in women undergoing cesarean delivery under spinal anesthesia","volume":"114","author":"Habib AS","year":"2012","unstructured":"Habib AS. A review of the impact of phenylephrine administration on maternal hemodynamics and maternal and neonatal outcomes in women undergoing cesarean delivery under spinal anesthesia. Anesth Analg. 2012, 114:377-90. 10.1213\/ANE.0b013e3182373a3e","journal-title":"Anesth Analg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181e1db21","article-title":"A double-blind, placebo-controlled trial of four fixed rate infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery","volume":"111","author":"Allen TK","year":"2010","unstructured":"Allen TK, George RB, White WD, Muir HA, Habib AS. A double-blind, placebo-controlled trial of four fixed rate infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery. Anesth Analg. 2010, 111:1221-9. 10.1213\/ANE.0b013e3181e1db21","journal-title":"Anesth Analg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000099782.78002.30","article-title":"Prophylactic phenylephrine infusion for preventing hypotension during spinal anesthesia for cesarean delivery","volume":"98","author":"Ngan Kee WD","year":"2004","unstructured":"Ngan Kee WD, Khaw KS, Ng FF, Lee BB. Prophylactic phenylephrine infusion for preventing hypotension during spinal anesthesia for cesarean delivery. Anesth Analg. 2004, 98:815-21, table of contents. 10.1213\/01.ane.0000099782.78002.30","journal-title":"Anesth Analg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/anae.12445","article-title":"Prophylactic phenylephrine for caesarean section under spinal anaesthesia: systematic review and meta-analysis","volume":"69","author":"Heesen M","year":"2014","unstructured":"Heesen M, K\u00f6lhr S, Rossaint R, Straube S. Prophylactic phenylephrine for caesarean section under spinal anaesthesia: systematic review and meta-analysis. Anaesthesia. 2014, 69:143-65. 10.1111\/anae.12445","journal-title":"Anaesthesia"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-017-1034-6","article-title":"A randomized trial of phenylephrine infusion versus bolus dosing for nausea and vomiting during cesarean delivery in obese women","volume":"65","author":"George RB","year":"2018","unstructured":"George RB, McKeen DM, Dominguez JE, Allen TK, Doyle PA, Habib AS. A randomized trial of phenylephrine infusion versus bolus dosing for nausea and vomiting during cesarean delivery in obese women. Can J Anaesth. 2018, 65:254-62. 10.1007\/s12630-017-1034-6","journal-title":"Can J Anaesth"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/169457-comparing-the-effect-of-phenylephrine-bolus-and-phenylephrine-infusion-for-maintaining-arterial-blood-pressure-during-cesarean-delivery-under-spinal-anesthesia-a-randomized-prospective-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:02:53Z","timestamp":1707508973000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/169457-comparing-the-effect-of-phenylephrine-bolus-and-phenylephrine-infusion-for-maintaining-arterial-blood-pressure-during-cesarean-delivery-under-spinal-anesthesia-a-randomized-prospective-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,31]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.42713","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7,31]]}}}