{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T16:18:03Z","timestamp":1789402683066,"version":"build-2803163510"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,31]]},"DOI":"10.7759\/cureus.42763","type":"journal-article","created":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T22:49:01Z","timestamp":1690843741000},"source":"Crossref","is-referenced-by-count":5,"title":["Anti-SOX-1 Antibody-Positive Paraneoplastic Limbic Encephalitis Diagnosed During Small Cell Lung Cancer Treatment"],"prefix":"10.7759","author":[{"given":"Toru","family":"Yoshino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoji","family":"Hoshina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiko","family":"Ishimine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-2-22","article-title":"Paraneoplastic neurological syndromes","volume":"2","author":"Honnorat J","year":"2007","unstructured":"Honnorat J, Antoine JC. Paraneoplastic neurological syndromes. Orphanet J Rare Dis. 2007, 2:22. 10.1186\/1750-1172-2-22","journal-title":"Orphanet J Rare Dis"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13290","article-title":"Anti-SOX1 antibody-positive paraneoplastic neurological syndrome presenting with Lambert-Eaton myasthenic syndrome and small cell lung cancer: a case report","volume":"11","author":"Li C","year":"2020","unstructured":"Li C, Wang X, Sun L, Deng H, Han Y, Zheng W. Anti-SOX1 antibody-positive paraneoplastic neurological syndrome presenting with Lambert-Eaton myasthenic syndrome and small cell lung cancer: a case report. Thorac Cancer. 2020, 11:465-9. 10.1111\/1759-7714.13290","journal-title":"Thorac Cancer"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2009.341","article-title":"Paraneoplastic neurologic syndrome in the PNS Euronetwork database: a European study from 20 centers","volume":"67","author":"Giometto B","year":"2010","unstructured":"Giometto B, Grisold W, Vitaliani R, Graus F, Honnorat J, Bertolini G. Paraneoplastic neurologic syndrome in the PNS Euronetwork database: a European study from 20 centers. Arch Neurol. 2010, 67:330-5. 10.1001\/archneurol.2009.341","journal-title":"Arch Neurol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2005.03.020","article-title":"Anti-glial nuclear antibody: marker of lung cancer-related paraneoplastic neurological syndromes","volume":"165","author":"Graus F","year":"2005","unstructured":"Graus F, Vincent A, Pozo-Rosich P, Sabater L, Saiz A, Lang B, Dalmau J. Anti-glial nuclear antibody: marker of lung cancer-related paraneoplastic neurological syndromes. J Neuroimmunol. 2005, 165:166-71. 10.1016\/j.jneuroim.2005.03.020","journal-title":"J Neuroimmunol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.6169","article-title":"SOX antibodies in small-cell lung cancer and Lambert-Eaton myasthenic syndrome: frequency and relation with survival","volume":"27","author":"Titulaer MJ","year":"2009","unstructured":"Titulaer MJ, Klooster R, Potman M, et al.. SOX antibodies in small-cell lung cancer and Lambert-Eaton myasthenic syndrome: frequency and relation with survival. J Clin Oncol. 2009, 27:4260-7. 10.1200\/JCO.2008.20.6169","journal-title":"J Clin Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000281663.81079.24","article-title":"SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome","volume":"70","author":"Sabater L","year":"2008","unstructured":"Sabater L, Titulaer M, Saiz A, Verschuuren J, G\u00fcre AO, Graus F. SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome. Neurology. 2008, 70:924-8. 10.1212\/01.wnl.0000281663.81079.24","journal-title":"Neurology"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1856-1","article-title":"Cefepime-induced neurotoxicity: a systematic review","volume":"21","author":"Payne LE","year":"2017","unstructured":"Payne LE, Gagnon DJ, Riker RR, Seder DB, Glisic EK, Morris JG, Fraser GL. Cefepime-induced neurotoxicity: a systematic review. Crit Care. 2017, 21:276. 10.1186\/s13054-017-1856-1","journal-title":"Crit Care"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofx170","article-title":"Characterizing cefepime neurotoxicity: a systematic review","volume":"4","author":"Appa AA","year":"2017","unstructured":"Appa AA, Jain R, Rakita RM, Hakimian S, Pottinger PS. Characterizing cefepime neurotoxicity: a systematic review. Open Forum Infect Dis. 2017, 4:ofx170. 10.1093\/ofid\/ofx170","journal-title":"Open Forum Infect Dis"},{"key":"ref9","article-title":"Paraneoplastic limbic encephalitis in an elderly patient with small cell lung carcinoma","volume":"79","author":"White D","year":"2010","unstructured":"White D, Beringer T. Paraneoplastic limbic encephalitis in an elderly patient with small cell lung carcinoma. Ulster Med J. 2010, 79:22-4.","journal-title":"Ulster Med J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00401-9","article-title":"A clinical approach to diagnosis of autoimmune encephalitis","volume":"15","author":"Graus F","year":"2016","unstructured":"Graus F, Titulaer MJ, Balu R, et al.. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol. 2016, 15:391-404. 10.1016\/S1474-4422(15)00401-9","journal-title":"Lancet Neurol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.53.8.1719","article-title":"Clinical outcome of patients with anti-Hu-associated encephalomyelitis after treatment of the tumor","volume":"53","author":"Keime-Guibert F","year":"1999","unstructured":"Keime-Guibert F, Graus F, Bro\u00ebt P, Re\u00f1\u00e9 R, Molinuevo JL, Ascaso C, Delattre JY. Clinical outcome of patients with anti-Hu-associated encephalomyelitis after treatment of the tumor. Neurology. 1999, 53:1719-23. 10.1212\/wnl.53.8.1719","journal-title":"Neurology"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1708712","article-title":"Antibody-mediated encephalitis","volume":"378","author":"Dalmau J","year":"2018","unstructured":"Dalmau J, Graus F. Antibody-mediated encephalitis. N Engl J Med. 2018, 378:840-51. 10.1056\/NEJMra1708712","journal-title":"N Engl J Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.6.923","article-title":"Limbic encephalitis and small cell lung cancer. Clinical and immunological features","volume":"120 ( Pt 6)","author":"Alamowitch S","year":"1997","unstructured":"Alamowitch S, Graus F, Uchuya M, Re\u00f1\u00e9 R, Bescansa E, Delattre JY. Limbic encephalitis and small cell lung cancer. Clinical and immunological features. Brain. 1997, 120 ( Pt 6):923-8. 10.1093\/brain\/120.6.923","journal-title":"Brain"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2017.1395125","article-title":"Assessment of neuronal autoantibodies in patients with small cell lung cancer treated with chemotherapy with or without ipilimumab","volume":"7","author":"Hardy-Werbin M","year":"2018","unstructured":"Hardy-Werbin M, Arp\u00ed O, Taus A, et al.. Assessment of neuronal autoantibodies in patients with small cell lung cancer treated with chemotherapy with or without ipilimumab. Oncoimmunology. 2018, 7:e1395125. 10.1080\/2162402X.2017.1395125","journal-title":"Oncoimmunology"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/169762-anti-sox-1-antibody-positive-paraneoplastic-limbic-encephalitis-diagnosed-during-small-cell-lung-cancer-treatment","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:02:46Z","timestamp":1707508966000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/169762-anti-sox-1-antibody-positive-paraneoplastic-limbic-encephalitis-diagnosed-during-small-cell-lung-cancer-treatment"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,31]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.42763","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7,31]]}}}