{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T15:24:04Z","timestamp":1779377044752,"version":"3.53.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,19]]},"DOI":"10.7759\/cureus.43752","type":"journal-article","created":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T14:25:18Z","timestamp":1692455118000},"source":"Crossref","is-referenced-by-count":3,"title":["Clinical Characteristics of Ischemic Stroke Patients <50 Years Old at a University Hospital: A Retrospective Descriptive Study"],"prefix":"10.7759","author":[{"given":"Abdullah","family":"Alkutbi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh","family":"Binmahfooz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rawan H","family":"AlSaidlani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasana B","family":"Albeirouti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Kamal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Alalawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed N","family":"Aljehani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsin","family":"Khared","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar A","family":"Ayoub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31460-X","article-title":"Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015","volume":"388","year":"2016","unstructured":"Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015. a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016, 388:1603-58. 10.1016\/S0140-6736(16)31460-X","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afp196","article-title":"Stroke knowledge and awareness: an integrative review of the evidence","volume":"39","author":"Jones SP","year":"2010","unstructured":"Jones SP, Jenkinson AJ, Leathley MJ, Watkins CL. Stroke knowledge and awareness: an integrative review of the evidence. Age Ageing. 2010, 39:11-22. 10.1093\/ageing\/afp196","journal-title":"Age Ageing"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00252-0","article-title":"Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"20","year":"2021","unstructured":"Global, regional, and national burden of stroke and its risk factors, 1990-2019. a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021, 20:795-820. 10.1016\/S1474-4422(21)00252-0","journal-title":"Lancet Neurol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30034-1","article-title":"Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","year":"2019","unstructured":"Global, regional, and national burden of stroke, 1990-2016. a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019, 18:439-58. 10.1016\/S1474-4422(19)30034-1","journal-title":"Lancet Neurol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1804492","article-title":"Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016","volume":"379","author":"Feigin VL","year":"2018","unstructured":"Feigin VL, Nguyen G, Cercy K, et al.. Global, regional, and country-specific lifetime risks of stroke, 1990 and 2016. N Engl J Med. 2018, 379:2429-37. 10.1056\/NEJMoa1804492","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-029079","article-title":"Analysis on geographic variations in hospital deaths and endovascular therapy in ischaemic stroke patients: an observational cross-sectional study in China","volume":"9","author":"Chen H","year":"2019","unstructured":"Chen H, Shi L, Wang N, et al.. Analysis on geographic variations in hospital deaths and endovascular therapy in ischaemic stroke patients: an observational cross-sectional study in China. BMJ Open. 2019, 9:e029079. 10.1136\/bmjopen-2019-029079","journal-title":"BMJ Open"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/hs1101.098524","article-title":"Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank","volume":"32","author":"Grau AJ","year":"2001","unstructured":"Grau AJ, Weimar C, Buggle F, et al.. Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German stroke data bank. Stroke. 2001, 32:2559-66. 10.1161\/hs1101.098524","journal-title":"Stroke"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000217652.42273.02","article-title":"Health-related quality of life among young adults with ischemic stroke on long-term follow-up","volume":"37","author":"Naess H","year":"2006","unstructured":"Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Health-related quality of life among young adults with ischemic stroke on long-term follow-up. Stroke. 2006, 37:1232-6. 10.1161\/01.STR.0000217652.42273.02","journal-title":"Stroke"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.112.662866","article-title":"Demographic and geographic vascular risk factor differences in European young adults with ischemic stroke: the 15 cities young stroke study","volume":"43","author":"Putaala J","year":"2012","unstructured":"Putaala J, Yesilot N, Waje-Andreassen U, et al.. Demographic and geographic vascular risk factor differences in European young adults with ischemic stroke: the 15 cities young stroke study. Stroke. 2012, 43:2624-30. 10.1161\/STROKEAHA.112.662866","journal-title":"Stroke"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268481","article-title":"Causes of ischemic stroke in young adults versus non-young adults: a multicenter hospital-based observational study","volume":"17","author":"Ohya Y","year":"2022","unstructured":"Ohya Y, Matsuo R, Sato N, et al.. Causes of ischemic stroke in young adults versus non-young adults: a multicenter hospital-based observational study. PLoS One. 2022, 17:e0268481. 10.1371\/journal.pone.0268481","journal-title":"PLoS One"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(18)30233-3","article-title":"Epidemiology, aetiology, and management of ischaemic stroke in young adults","volume":"17","author":"Ekker MS","year":"2018","unstructured":"Ekker MS, Boot EM, Singhal AB, et al.. Epidemiology, aetiology, and management of ischaemic stroke in young adults. Lancet Neurol. 2018, 17:790-801. 10.1016\/s1474-4422(18)30233-3","journal-title":"Lancet Neurol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000522","article-title":"Stroke in young adults: five new things","volume":"8","author":"Bhatt N","year":"2018","unstructured":"Bhatt N, Malik AM, Chaturvedi S. Stroke in young adults: five new things. Neurol Clin Pract. 2018, 8:501-6. 10.1212\/CPJ.0000000000000522","journal-title":"Neurol Clin Pract"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2021.01.015","article-title":"Clinical and economic burden of stroke among young, midlife, and older adults in the United States, 2002-2017","volume":"5","author":"Khan SU","year":"2021","unstructured":"Khan SU, Khan MZ, Khan MU, et al.. Clinical and economic burden of stroke among young, midlife, and older adults in the United States, 2002-2017. Mayo Clin Proc Innov Qual Outcomes. 2021, 5:431-41. 10.1016\/j.mayocpiqo.2021.01.015","journal-title":"Mayo Clin Proc Innov Qual Outcomes"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8502758","article-title":"Preference and values of stroke interventions, Kingdom of Saudi Arabia","volume":"2019","author":"Alamri R","year":"2019","unstructured":"Alamri R, Alhazzani A, Alqahtani SA, Al-Alfard H, Mukhtar S, Alshahrany K, Asiri F. Preference and values of stroke interventions, Kingdom of Saudi Arabia. Neurol Res Int. 2019, 2019:8502758. 10.1155\/2019\/8502758","journal-title":"Neurol Res Int"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S373493","article-title":"Uric acid and clinical outcomes in young patients with ischemic stroke","volume":"18","author":"Liu Y","year":"2022","unstructured":"Liu Y, Liu X, Jia J, Guo J, Li G, Zhao X. Uric acid and clinical outcomes in young patients with ischemic stroke. Neuropsychiatr Dis Treat. 2022, 18:2219-28. 10.2147\/NDT.S373493","journal-title":"Neuropsychiatr Dis Treat"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.925764","article-title":"Clinical characteristics and outcomes of ischemic stroke patients during Ramadan vs. non-Ramadan months: Is there a difference?","volume":"13","author":"Alotaibi N","year":"2022","unstructured":"Alotaibi N, Aldriweesh MA, Alhasson MA, et al.. Clinical characteristics and outcomes of ischemic stroke patients during Ramadan vs. non-Ramadan months: Is there a difference?. Front Neurol. 2022, 13:925764. 10.3389\/fneur.2022.925764","journal-title":"Front Neurol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.707420","article-title":"Stroke seasonality and weather Association in a Middle East country: a single tertiary center experience","volume":"12","author":"Alghamdi SA","year":"2021","unstructured":"Alghamdi SA, Aldriweesh MA, Al Bdah BA, et al.. Stroke seasonality and weather Association in a Middle East country: a single tertiary center experience. Front Neurol. 2021, 12:707420. 10.3389\/fneur.2021.707420","journal-title":"Front Neurol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0000000000000040","article-title":"Which comorbidities and complications predict ischemic stroke recovery and length of stay?","volume":"20","author":"Mohamed W","year":"2015","unstructured":"Mohamed W, Bhattacharya P, Shankar L, Chaturvedi S, Madhavan R. Which comorbidities and complications predict ischemic stroke recovery and length of stay?. Neurologist. 2015, 20:27-32. 10.1097\/NRL.0000000000000040","journal-title":"Neurologist"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.000590","article-title":"Factors associated with length of hospitalization in patients admitted with transient ischemic attack in United States","volume":"44","author":"Qureshi AI","year":"2013","unstructured":"Qureshi AI, Adil MM, Zacharatos H, Suri MF. Factors associated with length of hospitalization in patients admitted with transient ischemic attack in United States. Stroke. 2013, 44:1601-5. 10.1161\/STROKEAHA.111.000590","journal-title":"Stroke"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1191\/026921598676265330","article-title":"A study of the factors which influence the length of hospital stay of stroke patients","volume":"12","author":"Hakim EA","year":"1998","unstructured":"Hakim EA, Bakheit AM. A study of the factors which influence the length of hospital stay of stroke patients. Clin Rehabil. 1998, 12:151-6. 10.1191\/026921598676265330","journal-title":"Clin Rehabil"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.14467","article-title":"Stroke-related length of hospitalization trends and in-hospital mortality in Peru","volume":"10","author":"Lab\u00e1n-Seminario LM","year":"2022","unstructured":"Lab\u00e1n-Seminario LM, Carrillo-Larco RM, Bernab\u00e9-Ortiz A. Stroke-related length of hospitalization trends and in-hospital mortality in Peru. PeerJ. 2022, 10:e14467. 10.7717\/peerj.14467","journal-title":"PeerJ"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.12932","article-title":"Prevalence of diabetes and its effects on stroke\u00a0outcomes: A meta-analysis and literature review","volume":"10","author":"Lau LH","year":"2019","unstructured":"Lau LH, Lew J, Borschmann K, Thijs V, Ekinci EI. Prevalence of diabetes and its effects on stroke\u00a0outcomes: A meta-analysis and literature review. J Diabetes Investig. 2019, 10:780-92. 10.1111\/jdi.12932","journal-title":"J Diabetes Investig"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/179551-clinical-characteristics-of-ischemic-stroke-patients-50-years-old-at-a-university-hospital-a-retrospective-descriptive-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:03:59Z","timestamp":1707509039000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/179551-clinical-characteristics-of-ischemic-stroke-patients-50-years-old-at-a-university-hospital-a-retrospective-descriptive-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,19]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.43752","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8,19]]}}}