{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T02:44:44Z","timestamp":1778035484914,"version":"3.51.4"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,31]]},"DOI":"10.7759\/cureus.44466","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T19:06:52Z","timestamp":1693508812000},"source":"Crossref","is-referenced-by-count":1,"title":["Pathologic Features, Treatment, and Clinical Outcomes of Lacrimal Gland Cancer"],"prefix":"10.7759","author":[{"given":"Jerome M","family":"Karp","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex J","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Belinsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Jacobson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zujun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Persky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Persky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babak","family":"Givi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moses M","family":"Tam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2012.02403.x","article-title":"Lacrimal gland lesions in Denmark between 1974 and 2007","volume":"91","author":"von Holstein SL","year":"2013","unstructured":"von Holstein SL, Therkildsen MH, Prause JU, Stenman G, Siersma VD, Heegaard S. Lacrimal gland lesions in Denmark between 1974 and 2007. Acta Ophthalmol. 2013, 91:349-54. 10.1111\/j.1755-3768.2012.02403.x","journal-title":"Acta Ophthalmol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000531","article-title":"Management of lacrimal gland carcinoma: lessons from the literature in the past 40 years","volume":"32","author":"Woo KI","year":"2016","unstructured":"Woo KI, Yeom A, Esmaeli B. Management of lacrimal gland carcinoma: lessons from the literature in the past 40 years. Ophthalmic Plast Reconstr Surg. 2016, 32:1-10. 10.1097\/IOP.0000000000000531","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.3.315","article-title":"Neoadjuvant intracarotid chemotherapy for treatment of advanced adenocystic carcinoma of the lacrimal gland","volume":"116","author":"Meldrum ML","year":"1998","unstructured":"Meldrum ML, Tse DT, Benedetto P. Neoadjuvant intracarotid chemotherapy for treatment of advanced adenocystic carcinoma of the lacrimal gland. Arch Ophthalmol. 1998, 116:315-21. 10.1001\/archopht.116.3.315","journal-title":"Arch Ophthalmol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.08.068","article-title":"Clinical analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma","volume":"141","author":"Tse DT","year":"2006","unstructured":"Tse DT, Benedetto P, Dubovy S, Schiffman JC, Feuer WJ. Clinical analysis of the effect of intraarterial cytoreductive chemotherapy in the treatment of lacrimal gland adenoid cystic carcinoma. Am J Ophthalmol. 2006, 141:44-53. 10.1016\/j.ajo.2005.08.068","journal-title":"Am J Ophthalmol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2014.2846","article-title":"Epidemiology and treatment of lacrimal gland tumors: a population-based cohort analysis","volume":"140","author":"Mallen-St Clair J","year":"2014","unstructured":"Mallen-St Clair J, Arshi A, Tajudeen B, Abemayor E, St John M. Epidemiology and treatment of lacrimal gland tumors: a population-based cohort analysis. JAMA Otolaryngol Head Neck Surg. 2014, 140:1110-6. 10.1001\/jamaoto.2014.2846","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814556624","article-title":"Epidemiological trends in malignant lacrimal gland tumors","volume":"152","author":"Andreoli MT","year":"2015","unstructured":"Andreoli MT, Aakalu V, Setabutr P. Epidemiological trends in malignant lacrimal gland tumors. Otolaryngol Head Neck Surg. 2015, 152:279-83. 10.1177\/0194599814556624","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.27109","article-title":"Current trends in the management of epithelial lacrimal gland tumors: a retrospective national cancer database analysis","volume":"14","author":"Ashok Kumar P","year":"2022","unstructured":"Ashok Kumar P, Wang D, Huang D, Paulraj S, Sivapiragasam A. Current trends in the management of epithelial lacrimal gland tumors: a retrospective national cancer database analysis. Cureus. 2022, 14:e27109. 10.7759\/cureus.27109","journal-title":"Cureus"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.2042","article-title":"Unusual lacrimal gland tumor epidemiology explained","volume":"141","author":"Belliveau MJ","year":"2015","unstructured":"Belliveau MJ. Unusual lacrimal gland tumor epidemiology explained. JAMA Otolaryngol Head Neck Surg. 2015, 141:946. 10.1001\/jamaoto.2015.2042","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.22608\/APO.201707","article-title":"An update on tumors of the lacrimal gland","volume":"6","author":"Andreasen S","year":"2017","unstructured":"Andreasen S, Esmaeli B, Holstein SL, Mikkelsen LH, Rasmussen PK, Heegaard S. An update on tumors of the lacrimal gland. Asia Pac J Ophthalmol (Phila). 2017, 6:159-72. 10.22608\/APO.201707","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"key":"ref10","article-title":"Unusual lacrimal gland tumor epidemiology explained","volume":"141","author":"Mallen-St Clair J","year":"2015","unstructured":"Mallen-St Clair J, Arshi A, St John M. Unusual lacrimal gland tumor epidemiology explained. JAMA Otolaryngol. 2015, 141:946-7.","journal-title":"JAMA Otolaryngol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000301","article-title":"Current treatment of lacrimal gland carcinoma","volume":"27","author":"Woo KI","year":"2016","unstructured":"Woo KI, Kim YD, Sa HS, Esmaeli B. Current treatment of lacrimal gland carcinoma. Curr Opin Ophthalmol. 2016, 27:449-56. 10.1097\/ICU.0000000000000301","journal-title":"Curr Opin Ophthalmol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.76.7.401","article-title":"Primary malignant neoplasms of the lacrimal gland","volume":"76","author":"Wright JE","year":"1992","unstructured":"Wright JE, Rose GE, Garner A. Primary malignant neoplasms of the lacrimal gland. Br J Ophthalmol. 1992, 76:401-7. 10.1136\/bjo.76.7.401","journal-title":"Br J Ophthalmol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-316142","article-title":"Prognostic factors for local recurrence and survival and impact of local treatments on survival in lacrimal gland carcinoma","volume":"105","author":"Ford JR","year":"2021","unstructured":"Ford JR, Rubin ML, Frank SJ, et al.. Prognostic factors for local recurrence and survival and impact of local treatments on survival in lacrimal gland carcinoma. Br J Ophthalmol. 2021, 105:768-74. 10.1136\/bjophthalmol-2020-316142","journal-title":"Br J Ophthalmol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.12.049","article-title":"American Joint Committee on Cancer classification predicts outcome of patients with lacrimal gland adenoid cystic carcinoma","volume":"116","author":"Ahmad SM","year":"2009","unstructured":"Ahmad SM, Esmaeli B, Williams M, et al.. American Joint Committee on Cancer classification predicts outcome of patients with lacrimal gland adenoid cystic carcinoma. Ophthalmology. 2009, 116:1210-5. 10.1016\/j.ophtha.2008.12.049","journal-title":"Ophthalmology"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/01.IOP.0000105518.72611.4F","article-title":"Outcomes in patients with adenoid cystic carcinoma of the lacrimal gland","volume":"20","author":"Esmaeli B","year":"2004","unstructured":"Esmaeli B, Ahmadi MA, Youssef A, et al.. Outcomes in patients with adenoid cystic carcinoma of the lacrimal gland. Ophthalmic Plast Reconstr Surg. 2004, 20:22-6. 10.1097\/01.IOP.0000105518.72611.4F","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000001106","article-title":"Eye-preserving surgery followed by adjuvant radiotherapy for lacrimal gland carcinoma: outcomes in 37 patients","volume":"34","author":"Woo KI","year":"2018","unstructured":"Woo KI, Sagiv O, Han J, Frank SJ, Kim YD, Esmaeli B. Eye-preserving surgery followed by adjuvant radiotherapy for lacrimal gland carcinoma: outcomes in 37 patients. Ophthalmic Plast Reconstr Surg. 2018, 34:570-4. 10.1097\/IOP.0000000000001106","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2018.07.024","article-title":"Long-term outcomes of globe-preserving surgery with proton beam radiation for adenoid cystic carcinoma of the lacrimal gland","volume":"195","author":"Wolkow N","year":"2018","unstructured":"Wolkow N, Jakobiec FA, Lee H, Sutula FC. Long-term outcomes of globe-preserving surgery with proton beam radiation for adenoid cystic carcinoma of the lacrimal gland. Am J Ophthalmol. 2018, 195:43-62. 10.1016\/j.ajo.2018.07.024","journal-title":"Am J Ophthalmol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24433","article-title":"Eye-sparing multidisciplinary approach for the management of lacrimal gland carcinoma","volume":"38","author":"Esmaeli B","year":"2016","unstructured":"Esmaeli B, Yin VT, Hanna EY, Kies MS, William WN Jr, Bell D, Frank SJ. Eye-sparing multidisciplinary approach for the management of lacrimal gland carcinoma. Head Neck. 2016, 38:1258-62. 10.1002\/hed.24433","journal-title":"Head Neck"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-020-01601-8","article-title":"Outcomes in patients with lacrimal gland carcinoma treated with definitive radiotherapy or eye-sparing surgery followed by adjuvant radiotherapy","volume":"15","author":"Lin YH","year":"2020","unstructured":"Lin YH, Huang SM, Yap WK, et al.. Outcomes in patients with lacrimal gland carcinoma treated with definitive radiotherapy or eye-sparing surgery followed by adjuvant radiotherapy. Radiat Oncol. 2020, 15:156. 10.1186\/s13014-020-01601-8","journal-title":"Radiat Oncol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/181385-pathologic-features-treatment-and-clinical-outcomes-of-lacrimal-gland-cancer","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:58:24Z","timestamp":1707508704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/181385-pathologic-features-treatment-and-clinical-outcomes-of-lacrimal-gland-cancer"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.44466","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8,31]]}}}