{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T21:04:44Z","timestamp":1776805484626,"version":"3.51.2"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,7]]},"DOI":"10.7759\/cureus.44844","type":"journal-article","created":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T14:14:58Z","timestamp":1694096098000},"source":"Crossref","is-referenced-by-count":1,"title":["Epinephrine-Containing Topical Anesthetic Gel Inducing Systemic Epinephrine Toxicity: A Case Report"],"prefix":"10.7759","author":[{"given":"MD J","family":"Fateha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Willsie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/s1808-8694(15)30791-6","article-title":"Topical use of adrenaline in different concentrations for endoscopic sinus surgery","volume":"75","author":"Sarmento Junior KM","year":"2009","unstructured":"Sarmento Junior KM, Tomita S, K\u00f3s AO. Topical use of adrenaline in different concentrations for endoscopic sinus surgery. Braz J Otorhinolaryngol. 2009, 75:280-9. 10.1016\/s1808-8694(15)30791-6","journal-title":"Braz J Otorhinolaryngol"},{"key":"ref2","article-title":"The consequence of epinephrine (adrenaline) overdose (Article in Lithuanian)","volume":"42","author":"Reingardiene D","year":"2006","unstructured":"Reingardiene D. The consequence of epinephrine (adrenaline) overdose (Article in Lithuanian). Medicina (Kaunas). 2006, 42:606-9.","journal-title":"Medicina (Kaunas)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2008.10.001","article-title":"The effects of topical epinephrine on haemodynamics and markers of tissue perfusion in burned and non-burned patients requiring skin grafting","volume":"35","author":"Papp AA","year":"2009","unstructured":"Papp AA, Uusaro AV, Ruokonen ET. The effects of topical epinephrine on haemodynamics and markers of tissue perfusion in burned and non-burned patients requiring skin grafting. Burns. 2009, 35:832-9. 10.1016\/j.burns.2008.10.001","journal-title":"Burns"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/1099-081x(199911)20:8<401::aid-bdd204>3.0.co;2-l","article-title":"Epinephrine absorption after different routes of administration in an animal model","volume":"20","author":"Gu X","year":"1999","unstructured":"Gu X, Simons FE, Simons KJ. Epinephrine absorption after different routes of administration in an animal model. Biopharm Drug Dispos. 1999, 20:401-5. 10.1002\/1099-081x(199911)20:8&lt;401::aid-bdd204&gt;3.0.co;2-l","journal-title":"Biopharm Drug Dispos"},{"key":"ref5","article-title":"Lidocaine Toxicity","author":"Torp KD","year":"2023","unstructured":"Torp KD, Metheny E, Simon LV. Lidocaine Toxicity. StatPearls [Internet], StatPearls Publishing, Treasure Island, FL; 2023."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.1275","article-title":"Lidocaine-induced systemic toxicity: a case report and review of literature","volume":"9","author":"Hasan B","year":"2017","unstructured":"Hasan B, Asif T, Hasan M. Lidocaine-induced systemic toxicity: a case report and review of literature. Cureus. 2017, 9:e1275. 10.7759\/cureus.1275","journal-title":"Cureus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/176694-epinephrine-containing-topical-anesthetic-gel-inducing-systemic-epinephrine-toxicity-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:05:39Z","timestamp":1707509139000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/176694-epinephrine-containing-topical-anesthetic-gel-inducing-systemic-epinephrine-toxicity-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,7]]},"references-count":6,"URL":"https:\/\/doi.org\/10.7759\/cureus.44844","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9,7]]}}}