{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:13:28Z","timestamp":1782846808736,"version":"3.54.5"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,6]]},"DOI":"10.7759\/cureus.46591","type":"journal-article","created":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T15:16:56Z","timestamp":1696605416000},"source":"Crossref","is-referenced-by-count":18,"title":["Low-Grade Appendiceal Mucinous Neoplasm: What Is the Best Treatment?"],"prefix":"10.7759","author":[{"given":"Murat","family":"Guner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cengiz","family":"Ayd\u0131n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/ags3.12241","article-title":"Survival outcomes of appendiceal mucinous neoplasms by histological type and stage: analysis of 266 cases in a multicenter collaborative retrospective clinical study","volume":"3","author":"Sueda T","year":"2019","unstructured":"Sueda T, Murata K, Takeda T, et al.. Survival outcomes of appendiceal mucinous neoplasms by histological type and stage: analysis of 266 cases in a multicenter collaborative retrospective clinical study. Ann Gastroenterol Surg. 2019, 3:291-300. 10.1002\/ags3.12241","journal-title":"Ann Gastroenterol Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2014.129","article-title":"Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei","volume":"28 Suppl 1","author":"Misdraji J","year":"2015","unstructured":"Misdraji J. Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei. Mod Pathol. 2015, 28 Suppl 1:S67-79. 10.1038\/modpathol.2014.129","journal-title":"Mod Pathol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/his.13975","article-title":"The 2019 WHO classification of tumours of the digestive system","volume":"76","author":"Nagtegaal ID","year":"2020","unstructured":"Nagtegaal ID, Odze RD, Klimstra D, et al.. The 2019 WHO classification of tumours of the digestive system. Histopathology. 2020, 76:182-8. 10.1111\/his.13975","journal-title":"Histopathology"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.3980","article-title":"A rare case of low-grade appendiceal mucinous neoplasm: a case report","volume":"11","author":"Gonzalez HH","year":"2019","unstructured":"Gonzalez HH, Herard K, Mijares MC. A rare case of low-grade appendiceal mucinous neoplasm: a case report. Cureus. 2019, 11:e3980. 10.7759\/cureus.3980","journal-title":"Cureus"},{"key":"ref5","article-title":"Appendiceal mucoceles and pseudomyxoma peritonei","volume":"175","author":"Landen S","year":"1992","unstructured":"Landen S, Bertrand C, Maddern GJ, Herman D, Pourbaix A, de Neve A, Schmitz A. Appendiceal mucoceles and pseudomyxoma peritonei. Surg Gynecol Obstet. 1992, 175:401-4.","journal-title":"Surg Gynecol Obstet"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181af6067","article-title":"Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence","volume":"33","author":"Pai RK","year":"2009","unstructured":"Pai RK, Beck AH, Norton JA, Longacre TA. Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence. Am J Surg Pathol. 2009, 33:1425-39. 10.1097\/PAS.0b013e3181af6067","journal-title":"Am J Surg Pathol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21054","article-title":"Consensus statement on the loco-regional treatment of appendiceal mucinous neoplasms with peritoneal dissemination (pseudomyxoma peritonei)","volume":"98","author":"Moran B","year":"2008","unstructured":"Moran B, Baratti D, Yan TD, Kusamura S, Deraco M. Consensus statement on the loco-regional treatment of appendiceal mucinous neoplasms with peritoneal dissemination (pseudomyxoma peritonei). J Surg Oncol. 2008, 98:277-82. 10.1002\/jso.21054","journal-title":"J Surg Oncol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2019.07.035","article-title":"Role of right hemicolectomy in patients with low-grade appendiceal mucinous adenocarcinoma","volume":"218","author":"Nasseri YY","year":"2019","unstructured":"Nasseri YY, Zhu R, Sutanto C, Wai C, Cohen JS, Ellenhorn J, Artinyan A. Role of right hemicolectomy in patients with low-grade appendiceal mucinous adenocarcinoma. Am J Surg. 2019, 218:1239-43. 10.1016\/j.amjsurg.2019.07.035","journal-title":"Am J Surg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000022071","article-title":"Comparative effectiveness of prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) for resected low-grade appendiceal mucinous neoplasm (LAMN): A protocol for systematic review and network meta-analysis","volume":"99","author":"Yang W","year":"2020","unstructured":"Yang W, Nie P, Liu X, Peng J. Comparative effectiveness of prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) for resected low-grade appendiceal mucinous neoplasm (LAMN): A protocol for systematic review and network meta-analysis. Medicine (Baltimore). 2020, 99:e22071. 10.1097\/MD.0000000000022071","journal-title":"Medicine (Baltimore)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-022-02639-w","article-title":"Low-grade mucinous neoplasms (LAMN) of the appendix in Germany between 2011 and 2018: a nationwide analysis based on data provided by the German Center for Cancer Registry Data (ZfKD) at the Robert Koch Institute (RKI)","volume":"407","author":"K\u00f6hler F","year":"2022","unstructured":"K\u00f6hler F, Reese L, Hendricks A, et al.. Low-grade mucinous neoplasms (LAMN) of the appendix in Germany between 2011 and 2018: a nationwide analysis based on data provided by the German Center for Cancer Registry Data (ZfKD) at the Robert Koch Institute (RKI). Langenbecks Arch Surg. 2022, 407:3615-22. 10.1007\/s00423-022-02639-w","journal-title":"Langenbecks Arch Surg"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000001378","article-title":"Predicting appendiceal tumors among patients with appendicitis","volume":"82","author":"Loftus TJ","year":"2017","unstructured":"Loftus TJ, Raymond SL, Sarosi GA Jr, et al.. Predicting appendiceal tumors among patients with appendicitis. J Trauma Acute Care Surg. 2017, 82:771-5. 10.1097\/TA.0000000000001378","journal-title":"J Trauma Acute Care Surg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2020.02.012","article-title":"Appendiceal tumours and pseudomyxoma peritonei: literature review with PSOGI\/EURACAN clinical practice guidelines for diagnosis and treatment","volume":"47","author":"Govaerts K","year":"2021","unstructured":"Govaerts K, Lurvink RJ, De Hingh IH, et al.. Appendiceal tumours and pseudomyxoma peritonei: literature review with PSOGI\/EURACAN clinical practice guidelines for diagnosis and treatment. Eur J Surg Oncol. 2021, 47:11-35. 10.1016\/j.ejso.2020.02.012","journal-title":"Eur J Surg Oncol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-006-0454-1","article-title":"Mucocele of the appendix","volume":"31","author":"Ruiz-Tovar J","year":"2007","unstructured":"Ruiz-Tovar J, Teruel DG, Casti\u00f1eiras VM, Dehesa AS, Quind\u00f3s PL, Molina EM. Mucocele of the appendix. World J Surg. 2007, 31:542-8. 10.1007\/s00268-006-0454-1","journal-title":"World J Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2017.01.006","article-title":"Radical appendectomy as an alternative to right colon resection in patients with epithelial appendiceal neoplasms","volume":"26","author":"Gonz\u00e1lez-Moreno S","year":"2017","unstructured":"Gonz\u00e1lez-Moreno S, Sugarbaker PH. Radical appendectomy as an alternative to right colon resection in patients with epithelial appendiceal neoplasms. Surg Oncol. 2017, 26:86-90. 10.1016\/j.suronc.2017.01.006","journal-title":"Surg Oncol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4393","article-title":"Right hemicolectomy does not confer a survival advantage in patients with mucinous carcinoma of the appendix and peritoneal seeding","volume":"91","author":"Gonz\u00e1lez-Moreno S","year":"2004","unstructured":"Gonz\u00e1lez-Moreno S, Sugarbaker PH. Right hemicolectomy does not confer a survival advantage in patients with mucinous carcinoma of the appendix and peritoneal seeding. Br J Surg. 2004, 91:304-11. 10.1002\/bjs.4393","journal-title":"Br J Surg"},{"key":"ref16","article-title":"Right psoas muscle\/aortoiliac groove recurrence: an unusual anatomic site for progression of epithelial tumors of the appendix","volume":"87","author":"Ortega-Perez G","year":"2002","unstructured":"Ortega-Perez G, Sugarbaker PH. Right psoas muscle\/aortoiliac groove recurrence: an unusual anatomic site for progression of epithelial tumors of the appendix. Int Surg. 2002, 87:212-6.","journal-title":"Int Surg"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2014-0246-OA","article-title":"Significance of proximal margin involvement in low-grade appendiceal mucinous neoplasms","volume":"139","author":"Arnason T","year":"2015","unstructured":"Arnason T, Kamionek M, Yang M, Yantiss RK, Misdraji J. Significance of proximal margin involvement in low-grade appendiceal mucinous neoplasms. Arch Pathol Lab Med. 2015, 139:518-21. 10.5858\/arpa.2014-0246-OA","journal-title":"Arch Pathol Lab Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-016-5588-2","article-title":"Low-grade appendiceal mucinous neoplasm of uncertain malignant potential (LAMN-UMP): prognostic factors and implications for treatment and follow-up","volume":"24","author":"Fournier K","year":"2017","unstructured":"Fournier K, Rafeeq S, Taggart M, et al.. Low-grade appendiceal mucinous neoplasm of uncertain malignant potential (LAMN-UMP): prognostic factors and implications for treatment and follow-up. Ann Surg Oncol. 2017, 24:187-93. 10.1245\/s10434-016-5588-2","journal-title":"Ann Surg Oncol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-020-0628-7","article-title":"Updated staging and patient outcomes in low-grade appendiceal mucinous neoplasms","volume":"34","author":"Ballentine SJ","year":"2021","unstructured":"Ballentine SJ, Carr J, Bekhor EY, Sarpel U, Polydorides AD. Updated staging and patient outcomes in low-grade appendiceal mucinous neoplasms. Mod Pathol. 2021, 34:104-15. 10.1038\/s41379-020-0628-7","journal-title":"Mod Pathol"},{"key":"ref20","article-title":"Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in appendix cancer A single-center experience","volume":"93","author":"Yuksel C","year":"2022","unstructured":"Yuksel C, Basceken SI, Ersen O, Culcu S, Mercan U, Bak\u0131rarar B, Unal AE. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in appendix cancer A single-center experience. Ann Ital Chir. 2022, 93:584-591.","journal-title":"Ann Ital Chir"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-3469-5","article-title":"Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: an emerging treatment option for advanced goblet cell tumors of the appendix","volume":"21","author":"McConnell YJ","year":"2014","unstructured":"McConnell YJ, Mack LA, Gui X, et al.. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: an emerging treatment option for advanced goblet cell tumors of the appendix. Ann Surg Oncol. 2014, 21:1975-82. 10.1245\/s10434-013-3469-5","journal-title":"Ann Surg Oncol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-019-07678-0","article-title":"Surveillance of low-grade appendiceal mucinous neoplasms with peritoneal metastases after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: are 5 years enough? A multisite experience","volume":"27","author":"Solomon D","year":"2020","unstructured":"Solomon D, Bekhor E, Leigh N, et al.. Surveillance of low-grade appendiceal mucinous neoplasms with peritoneal metastases after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: are 5 years enough? A multisite experience. Ann Surg Oncol. 2020, 27:147-53. 10.1245\/s10434-019-07678-0","journal-title":"Ann Surg Oncol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/194394-low-grade-appendiceal-mucinous-neoplasm-what-is-the-best-treatment","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:07:38Z","timestamp":1707509258000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/194394-low-grade-appendiceal-mucinous-neoplasm-what-is-the-best-treatment"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,6]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.46591","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10,6]]}}}