{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T13:07:15Z","timestamp":1763644035121},"reference-count":34,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,20]]},"DOI":"10.7759\/cureus.47375","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T12:46:23Z","timestamp":1697805983000},"source":"Crossref","is-referenced-by-count":1,"title":["A Rare Case of Penoscrotal Webbing and Extensive Hernias: An Anatomical Report With Genetic Insights"],"prefix":"10.7759","author":[{"given":"Carley M","family":"Olson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrey","family":"Frolov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meadow","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9261.70637","article-title":"Webbed penis: a new classification","volume":"15","author":"El-Koutby M","year":"2010","unstructured":"El-Koutby M, Mohamed Amin el G. Webbed penis: a new classification. J Indian Assoc Pediatr Surg. 2010, 15:50-2. 10.4103\/0971-9261.70637","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4103\/UROS.UROS_5_20","article-title":"Webbed penis: etiology, symptoms, surgical treatments, and outcomes","volume":"31","author":"Chao TC","year":"2020","unstructured":"Chao TC, Yang SS, Chang SJ, Lin CD. Webbed penis: etiology, symptoms, surgical treatments, and outcomes. Urol Sci. 2020, 31:200-5. 10.4103\/UROS.UROS_5_20","journal-title":"Urol Sci"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.diff.2018.08.001","article-title":"Development of the human penis and clitoris","volume":"103","author":"Baskin L","year":"2018","unstructured":"Baskin L, Shen J, Sinclair A, et al.. Development of the human penis and clitoris. Differentiation. 2018, 103:74-85. 10.1016\/j.diff.2018.08.001","journal-title":"Differentiation"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-196806000-00013","article-title":"Adult congenital penile deformity. Case report","volume":"41","author":"Glanz S","year":"1968","unstructured":"Glanz S. Adult congenital penile deformity. Case report. Plast Reconstr Surg. 1968, 41:579-80. 10.1097\/00006534-196806000-00013","journal-title":"Plast Reconstr Surg"},{"key":"ref5","unstructured":"Hernia. (2023). Accessed. March 2, 2023: https:\/\/my.clevelandclinic.org\/health\/diseases\/15757-hernia."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/31818161","article-title":"Male infertility: the role of imaging in diagnosis and management","volume":"85 Spec No 1","author":"Ammar T","year":"2012","unstructured":"Ammar T, Sidhu PS, Wilkins CJ. Male infertility: the role of imaging in diagnosis and management. Br J Radiol. 2012, 85 Spec No 1:S59-68. 10.1259\/bjr\/31818161","journal-title":"Br J Radiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1055\/a-0643-4524","article-title":"Ultrasound evaluation of testicular volume in patients with testicular microlithiasis","volume":"4","author":"Pedersen MR","year":"2018","unstructured":"Pedersen MR, Osther PJ, Rafaelsen SR. Ultrasound evaluation of testicular volume in patients with testicular microlithiasis. Ultrasound Int Open. 2018, 4:E99-E103. 10.1055\/a-0643-4524","journal-title":"Ultrasound Int Open"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1242\/dev.128.21.4241","article-title":"Unique functions of Sonic hedgehog signaling during external genitalia development","volume":"128","author":"Haraguchi R","year":"2001","unstructured":"Haraguchi R, Mo R, Hui C, et al.. Unique functions of Sonic hedgehog signaling during external genitalia development. Development. 2001, 128:4241-50. 10.1242\/dev.128.21.4241","journal-title":"Development"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.diff.2012.06.003","article-title":"Molecular mechanisms of external genitalia development","volume":"84","author":"Blaschko SD","year":"2012","unstructured":"Blaschko SD, Cunha GR, Baskin LS. Molecular mechanisms of external genitalia development. Differentiation. 2012, 84:261-8. 10.1016\/j.diff.2012.06.003","journal-title":"Differentiation"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/nature02061","article-title":"Hedgehog signalling in the mouse requires intraflagellar transport proteins","volume":"426","author":"Huangfu D","year":"2003","unstructured":"Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, Anderson KV. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature. 2003, 426:83-7. 10.1038\/nature02061","journal-title":"Nature"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2009.04.008","article-title":"The primary cilium as a cellular signaling center: lessons from disease","volume":"19","author":"Lancaster MA","year":"2009","unstructured":"Lancaster MA, Gleeson JG. The primary cilium as a cellular signaling center: lessons from disease. Curr Opin Genet Dev. 2009, 19:220-9. 10.1016\/j.gde.2009.04.008","journal-title":"Curr Opin Genet Dev"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2774","article-title":"The primary cilium: a signalling centre during vertebrate development","volume":"11","author":"Goetz SC","year":"2010","unstructured":"Goetz SC, Anderson KV. The primary cilium: a signalling centre during vertebrate development. Nat Rev Genet. 2010, 11:331-44. 10.1038\/nrg2774","journal-title":"Nat Rev Genet"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/path.3004","article-title":"Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling","volume":"226","author":"Christensen ST","year":"2012","unstructured":"Christensen ST, Clement CA, Satir P, Pedersen LB. Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling. J Pathol. 2012, 226:172-84. 10.1002\/path.3004","journal-title":"J Pathol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2259","article-title":"Subcellular spatial regulation of canonical Wnt signalling at the primary cilium","volume":"13","author":"Lancaster MA","year":"2011","unstructured":"Lancaster MA, Schroth J, Gleeson JG. Subcellular spatial regulation of canonical Wnt signalling at the primary cilium. Nat Cell Biol. 2011, 13:700-7. 10.1038\/ncb2259","journal-title":"Nat Cell Biol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1903","article-title":"The makings of maleness: towards an integrated view of male sexual development","volume":"7","author":"Wilhelm D","year":"2006","unstructured":"Wilhelm D, Koopman P. The makings of maleness: towards an integrated view of male sexual development. Nat Rev Genet. 2006, 7:620-31. 10.1038\/nrg1903","journal-title":"Nat Rev Genet"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2016.02.003","article-title":"Correction of congenital penoscrotal webbing in children: a retrospective review of three surgical techniques","volume":"12","author":"Bonitz RP","year":"2016","unstructured":"Bonitz RP, Hanna MK. Correction of congenital penoscrotal webbing in children: a retrospective review of three surgical techniques. J Pediatr Urol. 2016, 12:161.e1-5. 10.1016\/j.jpurol.2016.02.003","journal-title":"J Pediatr Urol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.105775","article-title":"Complete penoscrotal transposition: a three-stage procedure","volume":"28","author":"Somoza I","year":"2012","unstructured":"Somoza I, Palacios MG, Mendez R, Vela D. Complete penoscrotal transposition: a three-stage procedure. Indian J Urol. 2012, 28:450-2. 10.4103\/0970-1591.105775","journal-title":"Indian J Urol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s12262-012-0472-1","article-title":"Penoscrotal transposition: a case report","volume":"75","author":"Naren SD","year":"2013","unstructured":"Naren SD, Soren C, Subbarao PV. Penoscrotal transposition: a case report. Indian J Surg. 2013, 75:64-5. 10.1007\/s12262-012-0472-1","journal-title":"Indian J Surg"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-013-1128-1","article-title":"Skin as marker for collagen type I\/III ratio in abdominal wall fascia","volume":"18","author":"Peeters E","year":"2014","unstructured":"Peeters E, De Hertogh G, Junge K, Klinge U, Miserez M. Skin as marker for collagen type I\/III ratio in abdominal wall fascia. Hernia. 2014, 18:519-25. 10.1007\/s10029-013-1128-1","journal-title":"Hernia"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159\/000008740","article-title":"Abnormal collagen I to III distribution in the skin of patients with incisional hernia","volume":"32","author":"Klinge U","year":"2000","unstructured":"Klinge U, Si ZY, Zheng H, Schumpelick V, Bhardwaj RS, Klosterhalfen B. Abnormal collagen I to III distribution in the skin of patients with incisional hernia. Eur Surg Res. 2000, 32:43-8. 10.1159\/000008740","journal-title":"Eur Surg Res"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(74)90155-3","article-title":"Direct inguinal herniation in men: a disease of collagen","volume":"17","author":"Wagh PV","year":"1974","unstructured":"Wagh PV, Ieverich AP, Sun CN. Direct inguinal herniation in men: a disease of collagen. J Surg Res. 1974, 17:425-33. 10.1016\/0022-4804(74)90155-3","journal-title":"J Surg Res"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.167353","article-title":"Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia","volume":"58","author":"Asling B","year":"2009","unstructured":"Asling B, Jirholt J, Hammond P, et al.. Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia. Gut. 2009, 58:1063-9. 10.1136\/gut.2008.167353","journal-title":"Gut"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2019.05.003","article-title":"Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases","volume":"707","author":"Kuivaniemi H","year":"2019","unstructured":"Kuivaniemi H, Tromp G. Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases. Gene. 2019, 707:151-71. 10.1016\/j.gene.2019.05.003","journal-title":"Gene"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1177\/1457496918766694","article-title":"Type V collagen is persistently altered after inguinal hernia repair","volume":"107","author":"Lorentzen L","year":"2018","unstructured":"Lorentzen L, Henriksen NA, Juhl P, Mortensen JH, \u00c5gren MS, Karsdal MA, Jorgensen LN. Type V collagen is persistently altered after inguinal hernia repair. Scand J Surg. 2018, 107:212-7. 10.1177\/1457496918766694","journal-title":"Scand J Surg"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21647","article-title":"Identification of a mutation causing deficient BMP1\/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta","volume":"33","author":"Mart\u00ednez-Glez V","year":"2012","unstructured":"Mart\u00ednez-Glez V, Valencia M, Caparr\u00f3s-Mart\u00edn JA, et al.. Identification of a mutation causing deficient BMP1\/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta. Hum Mutat. 2012, 33:343-50. 10.1002\/humu.21647","journal-title":"Hum Mutat"},{"key":"ref26","article-title":"[Histological alterations of the muscle cremaster in certain inguinal-scrotal anomalies]","volume":"20","author":"Esteban RM","year":"2007","unstructured":"Esteban RM, Cueva C, S\u00e1nchez BV, Mariscal MG, Vargas JR, Garc\u00eda AL, Ruiz MG. [Histological alterations of the muscle cremaster in certain inguinal-scrotal anomalies]. Cir Pediatr. 2007, 20:44-8.","journal-title":"Cir Pediatr"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/79.4.610","article-title":"A new congenital non-progressive myopathy","volume":"79","author":"Magee KR","year":"1956","unstructured":"Magee KR, Shy GM. A new congenital non-progressive myopathy. Brain. 1956, 79:610-21. 10.1093\/brain\/79.4.610","journal-title":"Brain"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2012-008058","article-title":"Cricopharyngeal myotomy for cricopharyngeus stricture in an inclusion body myositis patient with hiatus hernia: a learning experience","volume":"2013","author":"Sanei-Moghaddam A","year":"2013","unstructured":"Sanei-Moghaddam A, Kumar S, Jani P, Brierley C. Cricopharyngeal myotomy for cricopharyngeus stricture in an inclusion body myositis patient with hiatus hernia: a learning experience. BMJ Case Rep. 2013, 2013:10.1136\/bcr-2012-008058","journal-title":"BMJ Case Rep"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.52","article-title":"Nemaline myopathy caused byTNNT1 mutations in a Dutch pedigree","volume":"2","author":"van der Pol WL","year":"2014","unstructured":"van der Pol WL, Leijenaar JF, Spliet WG, et al.. Nemaline myopathy caused byTNNT1 mutations in a Dutch pedigree. Mol Genet Genomic Med. 2014, 2:134-7. 10.1002\/mgg3.52","journal-title":"Mol Genet Genomic Med"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000455418.80357.d4","article-title":"Incisional hernia defect size and abdominal wall compliance","volume":"134","author":"Trzcinski B","year":"2014","unstructured":"Trzcinski B, Myers A, Kuzon, WM. Incisional hernia defect size and abdominal wall compliance. Plast Reconstr Surg. 2014, 134:72-3. 10.1097\/01.prs.0000455418.80357.d4","journal-title":"Plast Reconstr Surg"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.11138\/gchir\/2016.37.5.216","article-title":"Repair of an inguinoscrotal hernia in a patient with Becker muscular dystrophy","volume":"37","author":"Tatulli F","year":"2017","unstructured":"Tatulli F, Caraglia A, Delcuratolo A, Cassano S, Chetta GS. Repair of an inguinoscrotal hernia in a patient with Becker muscular dystrophy. G Chir. 2017, 37:216-9. 10.11138\/gchir\/2016.37.5.216","journal-title":"G Chir"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s10029-012-1032-0","article-title":"Histological findings in direct inguinal hernia : investigating the histological changes of the herniated groin looking forward to ascertain the pathogenesis of hernia disease","volume":"17","author":"Amato G","year":"2013","unstructured":"Amato G, Agrusa A, Romano G, et al.. Histological findings in direct inguinal hernia : investigating the histological changes of the herniated groin looking forward to ascertain the pathogenesis of hernia disease. Hernia. 2013, 17:757-63. 10.1007\/s10029-012-1032-0","journal-title":"Hernia"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2016.05.055","article-title":"Combined inguinal hernia in the elderly. Portraying the progression of hernia disease","volume":"33 Suppl 1","author":"Amato G","year":"2016","unstructured":"Amato G, Agrusa A, Rodolico V, et al.. Combined inguinal hernia in the elderly. Portraying the progression of hernia disease. Int J Surg. 2016, 33 Suppl 1:S20-9. 10.1016\/j.ijsu.2016.05.055","journal-title":"Int J Surg"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1080\/08941939.2018.1497734","article-title":"The septum inguinalis: a clue to hernia genesis?","volume":"33","author":"Amato G","year":"2020","unstructured":"Amato G, Cal\u00f2 P, Rodolico V, et al.. The septum inguinalis: a clue to hernia genesis?. J Invest Surg. 2020, 33:231-9. 10.1080\/08941939.2018.1497734","journal-title":"J Invest Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/198049-a-rare-case-of-penoscrotal-webbing-and-extensive-hernias-an-anatomical-report-with-genetic-insights","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:07:02Z","timestamp":1707509222000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/198049-a-rare-case-of-penoscrotal-webbing-and-extensive-hernias-an-anatomical-report-with-genetic-insights"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,20]]},"references-count":34,"URL":"https:\/\/doi.org\/10.7759\/cureus.47375","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10,20]]}}}