{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T00:36:38Z","timestamp":1707525398453},"reference-count":27,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,13]]},"DOI":"10.7759\/cureus.48739","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T16:18:17Z","timestamp":1699892297000},"source":"Crossref","is-referenced-by-count":0,"title":["A Comparative Cytocompatibility Assessment of Leukocyte-Platelet-Rich Fibrin (L-PRF) and Injectable Platelet-Rich Fibrin (I-PRF) on the Pre-osteoblastic MG-63 Cell Line in Chronic Periodontitis Patients: An In Vitro Study"],"prefix":"10.7759","author":[{"given":"Sheryl","family":"Dolly A.","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravishankar","family":"PL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prem","family":"Blaisie Rajula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sai Sri Soury","family":"Geddam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lochini","family":"S","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sindhujaa","family":"R","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Rashik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","article-title":"The potential role of growth and differentiation factors in periodontal regeneration","volume":"67","author":"William VG","year":"1996","unstructured":"William VG. The potential role of growth and differentiation factors in periodontal regeneration. J Periodontol. 1996, 67:545-553.","journal-title":"J Periodontol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.11.1624","article-title":"Position paper: guidelines for periodontal therapy","volume":"72","author":"Greenwell H","year":"2001","unstructured":"Greenwell H. Position paper: guidelines for periodontal therapy. J Periodontol. 2001, 72:1624-1628. 10.1902\/jop.2001.72.11.1624","journal-title":"J Periodontol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1976.47.5.256","article-title":"On the repair potential of periodontal tissues","volume":"47","author":"Melcher AH","year":"1976","unstructured":"Melcher AH. On the repair potential of periodontal tissues. J Periodontol. 1976, 47:256-260. 10.1902\/jop.1976.47.5.256","journal-title":"J Periodontol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/s8756-3282(96)00127-5","article-title":"Periodontal tissue engineering by growth factors","volume":"19","author":"Giannobile WV","year":"1996","unstructured":"Giannobile WV. Periodontal tissue engineering by growth factors. Bone. 1996, 19:23S-37S. 10.1016\/s8756-3282(96)00127-5","journal-title":"Bone"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/s0278-2391(97)90187-7","article-title":"Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery","volume":"1","author":"Whitman DH","year":"1997","unstructured":"Whitman DH, Berry RL, Green DM. Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg. 1997, 1:1294-1299. 10.1016\/s0278-2391(97)90187-7","journal-title":"J Oral Maxillofac Surg"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1051\/mbcb\/2022025","article-title":"Platelet concentrates in periodontics: review of in vivo studies and systematic reviews","volume":"28","author":"Anegundi RV","year":"2022","unstructured":"Anegundi RV, Shenoy SB, Kaukab SF, Talwar A. Platelet concentrates in periodontics: review of in vivo studies and systematic reviews. J Oral Maxillofac Surg. 2022, 28:10.1051\/mbcb\/2022025","journal-title":"J Oral Maxillofac Surg"},{"key":"ref7","article-title":"Une opportunit?? en paro-implantologie: Le PRF","volume":"42","author":"Choukroun J","year":"2001","unstructured":"Choukroun J, Adda F, Schoeffler C, Vervelle A. Une opportunit?? en paro-implantologie: Le PRF. Implantodontie. 2001, 42:55-62.","journal-title":"Implantodontie"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2174\/138920112800624391","article-title":"Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 1: periodontal and dentoalveolar surgery","volume":"13","author":"Del Corso M","year":"2012","unstructured":"Del Corso M, Vervelle A, Simonpieri A, Jimbo R, Inchingolo F, Sammartino G, Dohan Ehrenfest DM. Current knowledge and perspectives for the use of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in oral and maxillofacial surgery part 1: periodontal and dentoalveolar surgery. Curr Pharm Biotechnol. 2012, 13:1207-1230. 10.2174\/138920112800624391","journal-title":"Curr Pharm Biotechnol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2008.11.009","article-title":"Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF)","volume":"27","author":"Dohan Ehrenfest DM","year":"2009","unstructured":"Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol. 2009, 27:158-167. 10.1016\/j.tibtech.2008.11.009","journal-title":"Trends Biotechnol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00068-017-0767-9","article-title":"Reduction of relative centrifugation force within injectable platelet-rich-fibrin (PRF) concentrates advances patients\u2019 own inflammatory cells, platelets and growth factors: the first introduction to the low speed centrifugation concept","volume":"44","author":"Choukroun J","year":"2018","unstructured":"Choukroun J, Ghanaati S. Reduction of relative centrifugation force within injectable platelet-rich-fibrin (PRF) concentrates advances patients\u2019 own inflammatory cells, platelets and growth factors: the first introduction to the low speed centrifugation concept. Eur J Trauma Emerg Surg. 2018, 44:87-95. 10.1007%2Fs00068-017-0767-9","journal-title":"Eur J Trauma Emerg Surg"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1563\/aaid-joi-D-17-00231","article-title":"The application of three-dimensional printing model and platelet-rich fibrin technology in guided tissue regeneration surgery for severe bone defects","volume":"45","author":"Lei L","year":"2019","unstructured":"Lei L, Yu Y, Ke T, Sun W, Chen L. The application of three-dimensional printing model and platelet-rich fibrin technology in guided tissue regeneration surgery for severe bone defects. J Oral Implantol. 2019, 45:35-43. 10.1563\/aaid-joi-D-17-00231","journal-title":"J Oral Implantol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.36792","article-title":"Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells","volume":"108","author":"Zhang J","year":"2020","unstructured":"Zhang J, Yin C, Zhao Q, Zhao Z, Wang J, Miron RJ, Zhang Y. Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells. J Biomed Mater Res A. 2020, 108:61-68. 10.1002\/jbm.a.36792","journal-title":"J Biomed Mater Res A"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2555-2","article-title":"Injectable platelet rich fibrin: cell content, morphological, and protein characterization","volume":"23","author":"Varela HA","year":"2019","unstructured":"Varela HA, Souza JC, Nascimento RM, et al.. Injectable platelet rich fibrin: cell content, morphological, and protein characterization. Clin Oral Investig. 2019, 23:1309-1318. 10.1007\/s00784-018-2555-2","journal-title":"Clin Oral Investig"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041230316","article-title":"1 alpha, 25-dihydroxyvitamin D3 specific regulation of growth, morphology, and fibronectin in a human osteosarcoma cell line","volume":"123","author":"Franceschi RT","year":"1985","unstructured":"Franceschi RT, James WM, Zerlauth G. 1 alpha, 25-dihydroxyvitamin D3 specific regulation of growth, morphology, and fibronectin in a human osteosarcoma cell line. J Cell Physiol. 1985, 123:401-409. 10.1002\/jcp.1041230316","journal-title":"J Cell Physiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.07.008","article-title":"Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution","volume":"101","author":"Dohan DM","year":"2006","unstructured":"Dohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006, 101:e37-e44. 10.1016\/j.tripleo.2005.07.008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2063-9","article-title":"Injectable platelet rich fibrin (i-PRF): opportunities in regenerative dentistry?","volume":"21","author":"Miron RJ","year":"2017","unstructured":"Miron RJ, Fujioka-Kobayashi M, Hernandez M, Kandalam U, Zhang Y, Ghanaati S, Choukroun J. Injectable platelet rich fibrin (i-PRF): opportunities in regenerative dentistry?. Clin Oral Investig. 2017, 21:2619-2627. 10.1007\/s00784-017-2063-9","journal-title":"Clin Oral Investig"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-018-4309-2","article-title":"Uncoupling Warburg effect and stemness in CD133(+ve) cancer stem cells from Saos-2 (osteosarcoma) cell line under hypoxia","volume":"45","author":"Koka P","year":"2018","unstructured":"Koka P, Mundre RS, Rangarajan R, Chandramohan Y, Subramanian RK, Dhanasekaran A. Uncoupling Warburg effect and stemness in CD133(+ve) cancer stem cells from Saos-2 (osteosarcoma) cell line under hypoxia. Mol Biol Rep. 2018, 45:1653-1662. 10.1007\/s11033-018-4309-2","journal-title":"Mol Biol Rep"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1089\/ten.TEB.2016.0233","article-title":"Platelet-rich fibrin and soft tissue wound healing: a systematic review","volume":"23","author":"Miron RJ","year":"2017","unstructured":"Miron RJ, Fujioka-Kobayashi M, Bishara M, Zhang Y, Hernandez M, Choukroun J. Platelet-rich fibrin and soft tissue wound healing: a systematic review. Tissue Eng Part B Rev. 2017, 23:83-99. 10.1089\/ten.TEB.2016.0233","journal-title":"Tissue Eng Part B Rev"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/9781119406792.ch2","article-title":"Biological components of platelet rich fibrin: Growth factor release and cellular activity","author":"Fujioka\u2010Kobayashi M","year":"2017","unstructured":"Fujioka\u2010Kobayashi M, Miron RJ. Biological components of platelet rich fibrin: Growth factor release and cellular activity. Platelet Rich Fibrin in Regenerative Dentistry: Biological Background and Clinical Indications: Biological Background and Clinical Indications, One. Miron Rj, Choukroun J (ed): John Wiley &amp; Sons, Inc, 2017. 15-31. 10.1002\/9781119406792.ch2"},{"key":"ref20","article-title":"Physiological bases of bone regeneration I. Histology and physiology of bone tissue","volume":"11","author":"Fern\u00e1ndez-Tresguerres-Hern\u00e1ndez-Gil I","year":"2006","unstructured":"Fern\u00e1ndez-Tresguerres-Hern\u00e1ndez-Gil I, Alobera-Gracia MA, del-Canto-Pingarr\u00f3n M, Blanco-Jerez L. Physiological bases of bone regeneration I. Histology and physiology of bone tissue. Med Oral Patol Oral Cir Bucal. 2006, 11:47-51.","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2020.1773386","article-title":"Platelet-rich fibrin and concentrated growth factors as novel platelet concentrates for chronic hard-to-heal skin ulcers: a systematic review and Meta-analysis of randomized controlled trials","volume":"33","author":"Chen J","year":"2022","unstructured":"Chen J, Wan Y, Lin Y, Jiang H. Platelet-rich fibrin and concentrated growth factors as novel platelet concentrates for chronic hard-to-heal skin ulcers: a systematic review and Meta-analysis of randomized controlled trials. J Dermatolog Treat. 2022, 33:613-621. 10.1080\/09546634.2020.1773386","journal-title":"J Dermatolog Treat"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.30476\/dentjods.2022.93305.1709","article-title":"Comparative evaluation of the effect of two platelet concentrates (a-PRF and L-PRF) on the cellular activity of pre-osteoblastic MG-63 cell line: an in vitro study","volume":"24","author":"Esmaeilnejad A","year":"2023","unstructured":"Esmaeilnejad A, Talebi Ardakani M, Shokri M, Nima Hosseini Khou P, Kamani M. Comparative evaluation of the effect of two platelet concentrates (a-PRF and L-PRF) on the cellular activity of pre-osteoblastic MG-63 cell line: an in vitro study. J Dent (Shiraz). 2023, 24:235-244. 10.30476\/dentjods.2022.93305.1709","journal-title":"J Dent (Shiraz)"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3892%2Fmmr.2018.9472","article-title":"Platelet\u2011rich fibrin exudate promotes the proliferation and osteogenic differentiation of human periodontal ligament cells in vitro","volume":"18","author":"Li X","year":"2018","unstructured":"Li X, Yang H, Zhang Z, Yan Z, Lv H, Zhang Y, Wu B. Platelet\u2011rich fibrin exudate promotes the proliferation and osteogenic differentiation of human periodontal ligament cells in vitro. Mol Med Rep. 2018, 18:4477-4485. 10.3892%2Fmmr.2018.9472","journal-title":"Mol Med Rep"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/jre.13116","article-title":"An in vitro study into three different PRF preparations for osteogenesis potential","volume":"58","author":"Kosmidis K","year":"2023","unstructured":"Kosmidis K, Ehsan K, Pitzurra L, Loos B, Jansen I. An in vitro study into three different PRF preparations for osteogenesis potential. J Periodontal Res. 2023, 58:483-492. 10.1111\/jre.13116","journal-title":"J Periodontal Res"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1080\/09537104.2017.1293807","article-title":"Effects of an injectable platelet-rich fibrin on osteoblast behavior and bone tissue formation in comparison to platelet-rich plasma","volume":"29","author":"Wang X","year":"2018","unstructured":"Wang X, Zhang Y, Choukroun J, Ghanaati S, Miron RJ. Effects of an injectable platelet-rich fibrin on osteoblast behavior and bone tissue formation in comparison to platelet-rich plasma. Platelets. 2018, 29:48-55. 10.1080\/09537104.2017.1293807","journal-title":"Platelets"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.47162\/RJME.61.1.21","article-title":"Injectable platelet-rich fibrin influences the behavior of gingival mesenchymal stem cells","volume":"61","author":"Iozon S","year":"2020","unstructured":"Iozon S, Caracostea GV, P\u00e1ll E, et al.. Injectable platelet-rich fibrin influences the behavior of gingival mesenchymal stem cells. Rom J Morphol Embryol. 2020, 61:189-198. 10.47162\/RJME.61.1.21","journal-title":"Rom J Morphol Embryol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20246243","article-title":"Systematic comparison of the effect of four clinical-grade platelet rich hemoderivatives on osteoblast behaviour","volume":"20","author":"Fern\u00e1ndez-Medina T","year":"2019","unstructured":"Fern\u00e1ndez-Medina T, Vaquette C, Ivanovski S. Systematic comparison of the effect of four clinical-grade platelet rich hemoderivatives on osteoblast behaviour. Int J Mol Sci. 2019, 20:6243. 10.3390\/ijms20246243","journal-title":"Int J Mol Sci"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/201381-a-comparative-cytocompatibility-assessment-of-leukocyte-platelet-rich-fibrin-l-prf-and-injectable-platelet-rich-fibrin-i-prf-on-the-pre-osteoblastic-mg-63-cell-line-in-chronic-periodontitis-patients-an-in-vitro-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:09:53Z","timestamp":1707509393000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/201381-a-comparative-cytocompatibility-assessment-of-leukocyte-platelet-rich-fibrin-l-prf-and-injectable-platelet-rich-fibrin-i-prf-on-the-pre-osteoblastic-mg-63-cell-line-in-chronic-periodontitis-patients-an-in-vitro-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,13]]},"references-count":27,"URL":"https:\/\/doi.org\/10.7759\/cureus.48739","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11,13]]}}}