{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:57:57Z","timestamp":1792616277601,"version":"4.5.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,13]]},"DOI":"10.7759\/cureus.48746","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T18:12:52Z","timestamp":1699899172000},"source":"Crossref","is-referenced-by-count":5,"title":["Study Comparing Topical Ivermectin Versus Topical Permethrin in the Treatment of Scabies"],"prefix":"10.7759","author":[{"given":"Afshan","family":"Saeed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahan","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Iqbal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza","family":"Ismaeel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asher","family":"Mashhood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musarrat H","family":"Raza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Ammar","family":"Hamid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe1511805","article-title":"Scabies and global control of neglected tropical diseases","volume":"373","author":"Currie BJ","year":"2015","unstructured":"Currie BJ. Scabies and global control of neglected tropical diseases. N Engl J Med. 2015, 373:2371-2. 10.1056\/NEJMe1511805","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e32835eb851","article-title":"Epidemiology of scabies","volume":"26","author":"Fuller LC","year":"2013","unstructured":"Fuller LC. Epidemiology of scabies. Curr Opin Infect Dis. 2013, 26:123-6. 10.1097\/QCO.0b013e32835eb851","journal-title":"Curr Opin Infect Dis"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2006.01809.x","article-title":"Clinical features and associated morbidity of scabies in a rural community in Alagoas, Brazil","volume":"12","author":"Jackson A","year":"2007","unstructured":"Jackson A, Heukelbach J, Filho AF, J\u00fanior Ede B, Feldmeier H. Clinical features and associated morbidity of scabies in a rural community in Alagoas, Brazil. Trop Med Int Health. 2007, 12:493-502. 10.1111\/j.1365-3156.2006.01809.x","journal-title":"Trop Med Int Health"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.47750\/pnr.2022.13.S07.768","article-title":"Scabies is associated with more anxiety, depression, and impaired quality of life: a cross-sectional comparative study","volume":"30","author":"Seetan K","year":"2022","unstructured":"Seetan K, Khamees A, Abusohyon B, Alrababah HM. Scabies is associated with more anxiety, depression, and impaired quality of life: a cross-sectional comparative study. J Pharm Negative Results. 2022, 30:6314-20. 10.47750\/pnr.2022.13.S07.768","journal-title":"J Pharm Negative Results"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06591.x","article-title":"Epidemiology and morbidity of scabies and pediculosis capitis in resource-poor communities in Brazil","volume":"153","author":"Heukelbach J","year":"2005","unstructured":"Heukelbach J, Wilcke T, Winter B, Feldmeier H. Epidemiology and morbidity of scabies and pediculosis capitis in resource-poor communities in Brazil. Br J Dermatol. 2005, 153:150-6. 10.1111\/j.1365-2133.2005.06591.x","journal-title":"Br J Dermatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00132-2","article-title":"Prevalence of scabies and impetigo worldwide: a systematic review","volume":"15","author":"Romani L","year":"2015","unstructured":"Romani L, Steer AC, Whitfeld MJ, Kaldor JM. Prevalence of scabies and impetigo worldwide: a systematic review. Lancet Infect Dis. 2015, 15:960-7. 10.1016\/S1473-3099(15)00132-2","journal-title":"Lancet Infect Dis"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD000320.pub2","article-title":"Interventions for treating scabies","volume":"2007","author":"Strong M","year":"2007","unstructured":"Strong M, Johnstone P. Interventions for treating scabies. Cochrane Database Syst Rev. 2007, 2007:CD000320. 10.1002\/14651858.CD000320.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/med.2610130103","article-title":"Ivermectin, an antiparasitic agent","volume":"13","author":"Campbell WC","year":"1993","unstructured":"Campbell WC. Ivermectin, an antiparasitic agent. Med Res Rev. 1993, 13:61-79. 10.1002\/med.2610130103","journal-title":"Med Res Rev"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2001.018001063.x","article-title":"Topical ivermectin: a new successful treatment for scabies","volume":"18","author":"Victoria J","year":"2001","unstructured":"Victoria J, Trujillo R. Topical ivermectin: a new successful treatment for scabies. Pediatr Dermatol. 2001, 18:63-5. 10.1046\/j.1525-1470.2001.018001063.x","journal-title":"Pediatr Dermatol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1080\/00034989859348","article-title":"Control of human scabies by topical application of ivermectin","volume":"92","author":"Yeruham I","year":"1998","unstructured":"Yeruham I, Hadani A. Control of human scabies by topical application of ivermectin. Ann Trop Med Parasitol. 1998, 92:627-9. 10.1080\/00034989859348","journal-title":"Ann Trop Med Parasitol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1995.53.652","article-title":"Topical application of ivermectin for human ectoparasites","volume":"53","author":"Youssef MY","year":"1995","unstructured":"Youssef MY, Sadaka HA, Eissa MM, el-Ariny AF. Topical application of ivermectin for human ectoparasites. Am J Trop Med Hyg. 1995, 53:652-3. 10.4269\/ajtmh.1995.53.652","journal-title":"Am J Trop Med Hyg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2016.0757","article-title":"The treatment of scabies","volume":"113","author":"Dressler C","year":"2016","unstructured":"Dressler C, Rosumeck S, Sunderk\u00f6tter C, Werner RN, Nast A. The treatment of scabies. Dtsch Arztebl Int. 2016, 113:757-62. 10.3238\/arztebl.2016.0757","journal-title":"Dtsch Arztebl Int"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.09.006","article-title":"Ivermectin versus permethrin in the treatment of scabies: a systematic review and meta-analysis of randomized controlled trials","volume":"78","author":"Dhana A","year":"2018","unstructured":"Dhana A, Yen H, Okhovat JP, Cho E, Keum N, Khumalo NP. Ivermectin versus permethrin in the treatment of scabies: a systematic review and meta-analysis of randomized controlled trials. J Am Acad Dermatol. 2018, 78:194-8. 10.1016\/j.jaad.2017.09.006","journal-title":"J Am Acad Dermatol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.100571","article-title":"Comparative efficacy and safety of topical permethrin, topical ivermectin, and oral ivermectin in patients of uncomplicated scabies","volume":"78","author":"Chhaiya SB","year":"2012","unstructured":"Chhaiya SB, Patel VJ, Dave JN, Mehta DS, Shah HA. Comparative efficacy and safety of topical permethrin, topical ivermectin, and oral ivermectin in patients of uncomplicated scabies. Indian J Dermatol Venereol Leprol. 2012, 78:605-10. 10.4103\/0378-6323.100571","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012994","article-title":"Ivermectin and permethrin for treating scabies","volume":"4","author":"Rosumeck S","year":"2018","unstructured":"Rosumeck S, Nast A, Dressler C. Ivermectin and permethrin for treating scabies. Cochrane Database Syst Rev. 2018, 4:CD012994. 10.1002\/14651858.CD012994","journal-title":"Cochrane Database Syst Rev"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004691","article-title":"Scabies: advances in noninvasive diagnosis","volume":"10","author":"Micali G","year":"2016","unstructured":"Micali G, Lacarrubba F, Verz\u00ec AE, Chosidow O, Schwartz RA. Scabies: advances in noninvasive diagnosis. PLoS Negl Trop Dis. 2016, 10:e0004691. 10.1371\/journal.pntd.0004691","journal-title":"PLoS Negl Trop Dis"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159\/000077310","article-title":"Dermoscopy for the in vivo detection of sarcoptes scabiei","volume":"208","author":"Prins C","year":"2004","unstructured":"Prins C, Stucki L, French L, Saurat JH, Braun RP. Dermoscopy for the in vivo detection of sarcoptes scabiei. Dermatology. 2004, 208:241-3. 10.1159\/000077310","journal-title":"Dermatology"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18943","article-title":"The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies","volume":"183","author":"Engelman D","year":"2020","unstructured":"Engelman D, Yoshizumi J, Hay RJ, et al.. The 2020 International Alliance for the Control of Scabies Consensus Criteria for the Diagnosis of Scabies. Br J Dermatol. 2020, 183:808-20. 10.1111\/bjd.18943","journal-title":"Br J Dermatol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.48882","article-title":"Comparison of safety, efficacy, and cost effectiveness of benzyl benzoate, permethrin, and ivermectin in patients of scabies","volume":"41","author":"Bachewar NP","year":"2009","unstructured":"Bachewar NP, Thawani VR, Mali SN, Gharpure KJ, Shingade VP, Dakhale GN. Comparison of safety, efficacy, and cost effectiveness of benzyl benzoate, permethrin, and ivermectin in patients of scabies. Indian J Pharmacol. 2009, 41:9-14. 10.4103\/0253-7613.48882","journal-title":"Indian J Pharmacol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.2471\/blt.08.052308","article-title":"Ivermectin versus benzyl benzoate applied once or twice to treat human scabies in Dakar, Senegal: a randomized controlled trial","volume":"87","author":"Ly F","year":"2009","unstructured":"Ly F, Caumes E, Ndaw CA, Ndiaye B, Mah\u00e9 A. Ivermectin versus benzyl benzoate applied once or twice to treat human scabies in Dakar, Senegal: a randomized controlled trial. Bull World Health Organ. 2009, 87:424-30. 10.2471\/blt.08.052308","journal-title":"Bull World Health Organ"},{"key":"ref21","article-title":"The effect of a topical insecticide containing permethrin on the number of Culicoides midges caught near horses with and without insect bite hypersensitivity in the Netherlands","volume":"15","author":"De Raat IJ","year":"2008","unstructured":"De Raat IJ, Van den Boom R, Van Poppel M, et al.. The effect of a topical insecticide containing permethrin on the number of Culicoides midges caught near horses with and without insect bite hypersensitivity in the Netherlands. Tijdschr Diergeneeskd. 2008, 15:838-42.","journal-title":"Tijdschr Diergeneeskd"},{"key":"ref22","unstructured":"Medications. (2019). Accessed. November 11, 2023: https:\/\/www.cdc.gov\/parasites\/scabies\/health_professionals\/meds.html."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01481.x","article-title":"Treatment of scabies: comparison of permethrin 5% versus ivermectin","volume":"39","author":"Goldust M","year":"2012","unstructured":"Goldust M, Rezaee E, Hemayat S. Treatment of scabies: comparison of permethrin 5% versus ivermectin. J Dermatol. 2012, 39:545-7. 10.1111\/j.1346-8138.2011.01481.x","journal-title":"J Dermatol"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.2807\/ese.13.48.19052-en","article-title":"A persistent problem with scabies in and outside a nursing home in Amsterdam: indications for resistance to lindane and ivermectin","volume":"13","author":"van den Hoek JA","year":"2008","unstructured":"van den Hoek JA, van de Weerd JA, Baayen TD, Molenaar PM, Sonder GJ, van Ouwerkerk IM, de Vries HJ. A persistent problem with scabies in and outside a nursing home in Amsterdam: indications for resistance to lindane and ivermectin. Euro Surveill. 2008, 13:5-6. 10.2807\/ese.13.48.19052-en","journal-title":"Euro Surveill"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2008.10.023","article-title":"Outbreak of sarcoptic mange in alpacas (Vicugna pacos) and control with repeated subcutaneous ivermectin injections","volume":"159","author":"Twomey DF","year":"2009","unstructured":"Twomey DF, Birch ES, Schock A. Outbreak of sarcoptic mange in alpacas (Vicugna pacos) and control with repeated subcutaneous ivermectin injections. Vet Parasitol. 2009, 159:186-91. 10.1016\/j.vetpar.2008.10.023","journal-title":"Vet Parasitol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn161","article-title":"The effect of a single dose of oral ivermectin on pruritus in the homeless","volume":"62","author":"Badiaga S","year":"2008","unstructured":"Badiaga S, Foucault C, Rogier C, et al.. The effect of a single dose of oral ivermectin on pruritus in the homeless. J Antimicrob Chemother. 2008, 62:404-9. 10.1093\/jac\/dkn161","journal-title":"J Antimicrob Chemother"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1086\/521657","article-title":"Use of ivermectin to treat an institutional outbreak of scabies in a low-resource setting","volume":"28","author":"Garcia C","year":"2007","unstructured":"Garcia C, Iglesias D, Terashima A, Canales M, Gotuzzo E. Use of ivermectin to treat an institutional outbreak of scabies in a low-resource setting. Infect Control Hosp Epidemiol. 2007, 28:1337-8. 10.1086\/521657","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref28","article-title":"Comparison of efficacy of permethrin 5% cream with crotamiton 10% cream in patients with scabies","volume":"31","author":"Rao MA","year":"2019","unstructured":"Rao MA, Raza N, Faheem M, Saleem MA. Comparison of efficacy of permethrin 5% cream with crotamiton 10% cream in patients with scabies. J Ayub Med Coll Abbottabad. 2019, 31:230-2.","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90131-2","article-title":"A comparative study of oral ivermectin and topical permethrin cream in the treatment of scabies","volume":"42","author":"Usha V","year":"2000","unstructured":"Usha V, Gopalakrishnan Nair TV. A comparative study of oral ivermectin and topical permethrin cream in the treatment of scabies. J Am Acad Dermatol. 2000, 42:236-40. 10.1016\/S0190-9622(00)90131-2","journal-title":"J Am Acad Dermatol"},{"key":"ref30","article-title":"The efficacy of permethrin 5% vs. oral ivermectin for the treatment of scabies","volume":"59","author":"Ranjkesh MR","year":"2013","unstructured":"Ranjkesh MR, Naghili B, Goldust M, Rezaee E. The efficacy of permethrin 5% vs. oral ivermectin for the treatment of scabies. Ann Parasitol. 2013, 59:189-94.","journal-title":"Ann Parasitol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/185685-study-comparing-topical-ivermectin-versus-topical-permethrin-in-the-treatment-of-scabies","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:09:48Z","timestamp":1707509388000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/185685-study-comparing-topical-ivermectin-versus-topical-permethrin-in-the-treatment-of-scabies"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,13]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.48746","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11,13]]}}}