{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T07:04:30Z","timestamp":1760598270449},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,18]]},"DOI":"10.7759\/cureus.49025","type":"journal-article","created":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T01:20:32Z","timestamp":1700356832000},"source":"Crossref","is-referenced-by-count":1,"title":["Abrupt Withdrawal From Chronic High-Dose Zolpidem Use: A Case Report of Resulting Delirium"],"prefix":"10.7759","author":[{"given":"Harshal","family":"Awasthi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhimanyu","family":"Vohra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"Highlights of prescribing information. (2016). Accessed. November 17, 2023: http:\/\/US Food and Drug Administration."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200418001-00004","article-title":"The pharmacology and mechanisms of action of new generation, non-benzodiazepine hypnotic agents","volume":"18 Suppl 1","author":"Sanger DJ","year":"2004","unstructured":"Sanger DJ. The pharmacology and mechanisms of action of new generation, non-benzodiazepine hypnotic agents. CNS Drugs. 2004, 18 Suppl 1:9-45. 10.2165\/00023210-200418001-00004","journal-title":"CNS Drugs"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/026988119901304S03","article-title":"New insights into the mechanism of action of hypnotics","volume":"13","author":"Doble A","year":"1999","unstructured":"Doble A. New insights into the mechanism of action of hypnotics. J Psychopharmacol. 1999, 13:S11-20. 10.1177\/026988119901304S03","journal-title":"J Psychopharmacol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-5949.2010.00158.x","article-title":"Role of zolpidem in the management of insomnia","volume":"17","author":"Dang A","year":"2011","unstructured":"Dang A, Garg A, Rataboli PV. Role of zolpidem in the management of insomnia. CNS Neurosci Ther. 2011, 17:387-97. 10.1111\/j.1755-5949.2010.00158.x","journal-title":"CNS Neurosci Ther"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1345\/aph.17111","article-title":"Beyond benzodiazepines: alternative pharmacologic agents for the treatment of insomnia","volume":"32","author":"Wagner J","year":"1998","unstructured":"Wagner J, Wagner ML, Hening WA. Beyond benzodiazepines: alternative pharmacologic agents for the treatment of insomnia. Ann Pharmacother. 1998, 32:680-91. 10.1345\/aph.17111","journal-title":"Ann Pharmacother"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200326040-00004","article-title":"New drugs for insomnia: comparative tolerability of zopiclone, zolpidem and zaleplon","volume":"26","author":"Terzano MG","year":"2003","unstructured":"Terzano MG, Rossi M, Palomba V, Smerieri A, Parrino L. New drugs for insomnia: comparative tolerability of zopiclone, zolpidem and zaleplon. Drug Saf. 2003, 26:261-82. 10.2165\/00002018-200326040-00004","journal-title":"Drug Saf"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1080\/10550887.2014.882725","article-title":"An update on zolpidem abuse and dependence","volume":"33","author":"Victorri-Vigneau C","year":"2014","unstructured":"Victorri-Vigneau C, G\u00e9rardin M, Rousselet M, Guerlais M, Grall-Bronnec M, Jolliet P. An update on zolpidem abuse and dependence. J Addict Dis. 2014, 33:15-23. 10.1080\/10550887.2014.882725","journal-title":"J Addict Dis"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.9758\/cpn.2021.19.2.367","article-title":"Z-trip? A comprehensive overview and a case-series of zolpidem misuse","volume":"19","author":"Orsolini L","year":"2021","unstructured":"Orsolini L, Chiappini S, Grandinetti P, et al.. Z-trip? A comprehensive overview and a case-series of zolpidem misuse. Clin Psychopharmacol Neurosci. 2021, 19:367-87. 10.9758\/cpn.2021.19.2.367","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.12775\/JEHS.2022.12.09.018","article-title":"Review of the literature on the dangers of zolpidem use, its potential for abuse and addiction","volume":"12","author":"Skowro\u0144ska K","year":"2022","unstructured":"Skowro\u0144ska K, Chmura A, Pondel K, Cyboran K, Baciur P. Review of the literature on the dangers of zolpidem use, its potential for abuse and addiction. J Educ Health Sport. 2022, 12:144-9. 10.12775\/JEHS.2022.12.09.018","journal-title":"J Educ Health Sport"},{"key":"ref10","article-title":"Emergency department visits attributed to overmedication that involved the insomnia medication zolpidem.","author":"Bush DM","year":"2014","unstructured":"Bush DM. Emergency department visits attributed to overmedication that involved the insomnia medication zolpidem.. Bush DM (ed): Substance Abuse and Mental Health Services Administration (US), Rockville, MD; 2014."},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/0253717621992372","article-title":"Zolpidem for insomnia: a double-edged sword. A systematic literature review on zolpidem-induced complex sleep behaviors","volume":"43","author":"Mittal N","year":"2021","unstructured":"Mittal N, Mittal R, Gupta MC. Zolpidem for insomnia: a double-edged sword. A systematic literature review on zolpidem-induced complex sleep behaviors. Indian J Psychol Med. 2021, 43:373-81. 10.1177\/0253717621992372","journal-title":"Indian J Psychol Med"},{"key":"ref12","unstructured":"FDA drug safety communication. FDA approves new label changes and dosing for zolpidem products and a recommendation to avoid driving the day after using Ambien CR. (2023). Accessed: September 10: https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-drug-safety-communication-fda-approves-new-label-changes-a...."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.19926","article-title":"Zolpidem dependency and withdrawal seizure: a case report study","volume":"16","author":"Haji Seyed Javadi SA","year":"2014","unstructured":"Haji Seyed Javadi SA, Hajiali F, Nassiri-Asl M. Zolpidem dependency and withdrawal seizure: a case report study. Iran Red Crescent Med J. 2014, 16:e19926. 10.5812\/ircmj.19926","journal-title":"Iran Red Crescent Med J"},{"key":"ref14","article-title":"Zolpidem dependence and withdrawal seizure--report of two cases","volume":"23","author":"Wang LJ","year":"2011","unstructured":"Wang LJ, Ree SC, Chu CL, Juang YY. Zolpidem dependence and withdrawal seizure--report of two cases. Psychiatr Danub. 2011, 23:76-8.","journal-title":"Psychiatr Danub"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2010.22.4.451.e27","article-title":"Zolpidem withdrawal delirium: a case report","volume":"22","author":"Aggarwal A","year":"2010","unstructured":"Aggarwal A, Sharma DD. Zolpidem withdrawal delirium: a case report. J Neuropsychiatry Clin Neurosci. 2010, 22:451-o.e27-451.e28. 10.1176\/jnp.2010.22.4.451.e27","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3109\/14659890903013067","article-title":"Zolpidem withdrawal delirium, seizure, and acute psychosis: case reports and literature review","volume":"16","author":"Chien CC","year":"2011","unstructured":"Chien CC, Huanga HT, Lung FW, Lin CH. Zolpidem withdrawal delirium, seizure, and acute psychosis: case reports and literature review. J Subst Use. 2011, 16:330-8. 10.3109\/14659890903013067","journal-title":"J Subst Use"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.52314\/tjima.2023.v3i1.113","article-title":"Missing the woods for the trees in the management of zolpidem dependence: a case report","volume":"3","author":"Innamuri R","year":"2023","unstructured":"Innamuri R, Kattula D, Dholakia S, Akula V, Singh P. Missing the woods for the trees in the management of zolpidem dependence: a case report. Telangana J IMA. 2023, 3:30-2. 10.52314\/tjima.2023.v3i1.113","journal-title":"Telangana J IMA"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.23937\/2378-3656\/1410044","article-title":"Potentiating the adverse effects of zolpidem in a patient with alcohol dependence and SSRI use","volume":"2","author":"Chopra N","year":"2015","unstructured":"Chopra N, Rayapati A, Patel A. Potentiating the adverse effects of zolpidem in a patient with alcohol dependence and SSRI use. Clin Med Rev Case Rep. 2015, 2:44. 10.23937\/2378-3656\/1410044","journal-title":"Clin Med Rev Case Rep"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.89838","article-title":"Zolpidem withdrawal delirium","volume":"43","author":"Mattoo SK","year":"2011","unstructured":"Mattoo SK, Gaur N, Das PP. Zolpidem withdrawal delirium. Indian J Pharmacol. 2011, 43:729-30. 10.4103\/0253-7613.89838","journal-title":"Indian J Pharmacol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.4103\/0974-5009.120050","article-title":"Zolpidem induced delirium","volume":"40","author":"Chate SS","year":"2013","unstructured":"Chate SS, Nayak RB, Patil NM, Chattopadhyay S. Zolpidem induced delirium. J Sci Soc. 2013, 40:164-5. 10.4103\/0974-5009.120050","journal-title":"J Sci Soc"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/195208-abrupt-withdrawal-from-chronic-high-dose-zolpidem-use-a-case-report-of-resulting-delirium","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:52:25Z","timestamp":1707508345000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/195208-abrupt-withdrawal-from-chronic-high-dose-zolpidem-use-a-case-report-of-resulting-delirium"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,18]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.49025","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11,18]]}}}