{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T03:21:50Z","timestamp":1773717710739,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,15]]},"DOI":"10.7759\/cureus.50587","type":"journal-article","created":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T17:06:11Z","timestamp":1702659971000},"source":"Crossref","is-referenced-by-count":3,"title":["Leukemic Retinopathy: A Diagnostic Clue for Initial Detection and Prognosis of Leukemia"],"prefix":"10.7759","author":[{"given":"Tatyana","family":"Beketova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel","family":"Mordechaev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Murillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max D","family":"Schlesinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000309","article-title":"Ophthalmic manifestations of leukemia","volume":"27","author":"Talcott KE","year":"2016","unstructured":"Talcott KE, Garg RJ, Garg SJ. Ophthalmic manifestations of leukemia. Curr Opin Ophthalmol. 2016, 27:545-51. 10.1097\/ICU.0000000000000309","journal-title":"Curr Opin Ophthalmol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1989.7.10.1528","article-title":"A prospective ophthalmic evaluation of patients with acute myeloid leukemia: correlation of ocular and hematologic findings","volume":"7","author":"Karesh JW","year":"1989","unstructured":"Karesh JW, Goldman EJ, Reck K, Kelman SE, Lee EJ, Schiffer CA. A prospective ophthalmic evaluation of patients with acute myeloid leukemia: correlation of ocular and hematologic findings. J Clin Oncol. 1989, 7:1528-32. 10.1200\/JCO.1989.7.10.1528","journal-title":"J Clin Oncol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000073077","article-title":"Ocular involvement in leukemia--a study of 288 cases","volume":"217","author":"Reddy SC","year":"2003","unstructured":"Reddy SC, Jackson N, Menon BS. Ocular involvement in leukemia--a study of 288 cases. Ophthalmologica. 2003, 217:441-5. 10.1159\/000073077","journal-title":"Ophthalmologica"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2018.11.017","article-title":"Ocular manifestations in acute lymphoblastic leukemia: a five-year cohort study of pediatric patients","volume":"76","author":"de Queiroz Mendonca C","year":"2019","unstructured":"de Queiroz Mendonca C, Freire MV, Viana SS, Silva Tavares MK, Almeida Silva WM, Cipolotti R. Ocular manifestations in acute lymphoblastic leukemia: a five-year cohort study of pediatric patients. Leuk Res. 2019, 76:24-8. 10.1016\/j.leukres.2018.11.017","journal-title":"Leuk Res"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701308","article-title":"Ophthalmic manifestations of acute leukaemias: the ophthalmologist's role","volume":"18","author":"Sharma T","year":"2004","unstructured":"Sharma T, Grewal J, Gupta S, Murray PI. Ophthalmic manifestations of acute leukaemias: the ophthalmologist's role. Eye (Lond). 2004, 18:663-72. 10.1038\/sj.eye.6701308","journal-title":"Eye (Lond)"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58654-8","article-title":"Ocular manifestations of leukemia and results of treatment with intravitreal methotrexate","volume":"10","author":"Vishnevskia-Dai V","year":"2020","unstructured":"Vishnevskia-Dai V, Sella King S, Lekach R, Fabian ID, Zloto O. Ocular manifestations of leukemia and results of treatment with intravitreal methotrexate. Sci Rep. 2020, 10:1994. 10.1038\/s41598-020-58654-8","journal-title":"Sci Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.76.11.651","article-title":"Prognostic importance of ophthalmic manifestations in childhood leukaemia","volume":"76","author":"Ohkoshi K","year":"1992","unstructured":"Ohkoshi K, Tsiaras WG. Prognostic importance of ophthalmic manifestations in childhood leukaemia. Br J Ophthalmol. 1992, 76:651-5. 10.1136\/bjo.76.11.651","journal-title":"Br J Ophthalmol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/BF01204178","article-title":"Prognostic importance of retinopathy in acute leukemia","volume":"91","author":"Abu el-Asrar AM","year":"1995","unstructured":"Abu el-Asrar AM, al-Momen AK, Kangave D, Harakati MS. Prognostic importance of retinopathy in acute leukemia. Doc Ophthalmol. 1995, 91:273-81. 10.1007\/BF01204178","journal-title":"Doc Ophthalmol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2021.07.001","article-title":"Ophthalmologic manifestations as the initial presentation of chronic myeloid leukemia: a review","volume":"67","author":"Yassin MA","year":"2022","unstructured":"Yassin MA, Ata F, Mohamed SF, et al.. Ophthalmologic manifestations as the initial presentation of chronic myeloid leukemia: a review. Surv Ophthalmol. 2022, 67:530-43. 10.1016\/j.survophthal.2021.07.001","journal-title":"Surv Ophthalmol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0b013e31821cdf29","article-title":"Chronic myelogenous leukemia and retinopathy treated with imatinib","volume":"5","author":"Grunwald L","year":"2011","unstructured":"Grunwald L, Mehta S, Hogarty MD, Liu GT. Chronic myelogenous leukemia and retinopathy treated with imatinib. Retin Cases Brief Rep. 2011, 5:366-8. 10.1097\/ICB.0b013e31821cdf29","journal-title":"Retin Cases Brief Rep"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(02)01964-5","article-title":"Resolution of leukemic retinopathy following treatment with imatinib mesylate for chronic myelogenous leukemia","volume":"135","author":"Christoforidis JB","year":"2003","unstructured":"Christoforidis JB, DeAngelo DJ, D'Amico DJ. Resolution of leukemic retinopathy following treatment with imatinib mesylate for chronic myelogenous leukemia. Am J Ophthalmol. 2003, 135:398-400. 10.1016\/s0002-9394(02)01964-5","journal-title":"Am J Ophthalmol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1977.03630210112032","article-title":"Hydroxyurea in the prevention of the effects of leukostasis in acute leukemia","volume":"137","author":"Grund FM","year":"1977","unstructured":"Grund FM, Armitage JO, Burns P. Hydroxyurea in the prevention of the effects of leukostasis in acute leukemia. Arch Intern Med. 1977, 137:1246-7. 10.1001\/archinte.1977.03630210112032","journal-title":"Arch Intern Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1984.tb02190.x","article-title":"Hyperleucocytic retinopathy in chronic granulocytic leukaemia: the role of intensive leucapheresis","volume":"56","author":"Mehta AB","year":"1984","unstructured":"Mehta AB, Goldman JM, Kohner E. Hyperleucocytic retinopathy in chronic granulocytic leukaemia: the role of intensive leucapheresis. Br J Haematol. 1984, 56:661-7. 10.1111\/j.1365-2141.1984.tb02190.x","journal-title":"Br J Haematol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.oret.2017.08.009","article-title":"Leukemic retinopathy before and after chemotherapy","volume":"1","author":"Lezrek O","year":"2017","unstructured":"Lezrek O, Daoudi C, Laghmari M. Leukemic retinopathy before and after chemotherapy. Ophthalmol Retina. 2017, 1:561. 10.1016\/j.oret.2017.08.009","journal-title":"Ophthalmol Retina"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.127928","article-title":"Intravitreal methotrexate for treating vitreoretinal lymphoma: 10 years of experience","volume":"92","author":"Frenkel S","year":"2008","unstructured":"Frenkel S, Hendler K, Siegal T, Shalom E, Pe'er J. Intravitreal methotrexate for treating vitreoretinal lymphoma: 10 years of experience. Br J Ophthalmol. 2008, 92:383-8. 10.1136\/bjo.2007.127928","journal-title":"Br J Ophthalmol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/189754-leukemic-retinopathy-a-diagnostic-clue-for-initial-detection-and-prognosis-of-leukemia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:09:56Z","timestamp":1707509396000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/189754-leukemic-retinopathy-a-diagnostic-clue-for-initial-detection-and-prognosis-of-leukemia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,15]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.50587","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12,15]]}}}