{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T23:17:37Z","timestamp":1785453457858,"version":"3.56.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,12]]},"DOI":"10.7759\/cureus.52165","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T15:10:17Z","timestamp":1705072217000},"source":"Crossref","is-referenced-by-count":2,"title":["Knowledge of Dental Students and Practitioners About Medication-Related Osteonecrosis of the Jaw in the Central Region of Saudi Arabia"],"prefix":"10.7759","author":[{"given":"Meshal M","family":"Alghofaili","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Fareed","family":"Mohsin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada Mohammed","family":"Nahari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamim S","family":"Alkhalifah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayan Khaled","family":"Almazyad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed  K","family":"Alsaegh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.5125\/jkaoms.2017.43.4.272","article-title":"A case of bisphosphonate-related osteonecrosis of the jaw with a particularly unfavourable course: a case report","volume":"43","author":"Viviano M","year":"2017","unstructured":"Viviano M, Addamo A, Cocca S. A case of bisphosphonate-related osteonecrosis of the jaw with a particularly unfavourable course: a case report. J Korean Assoc Oral Maxillofac Surg. 2017, 43:272-5. 10.5125\/jkaoms.2017.43.4.272","journal-title":"J Korean Assoc Oral Maxillofac Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.25266","article-title":"Risks and benefits of bisphosphonate therapies","volume":"117","author":"Reyes C","year":"2016","unstructured":"Reyes C, Hitz M, Prieto-Alhambra D, Abrahamsen B. Risks and benefits of bisphosphonate therapies. J Cell Biochem. 2016, 117:20-8. 10.1002\/jcb.25266","journal-title":"J Cell Biochem"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.21433","article-title":"Knowledge of bisphosphonate-related osteonecrosis of the jaws among Mexican dentists","volume":"22","author":"Vinitzky-Brener I","year":"2017","unstructured":"Vinitzky-Brener I, Ib\u00e1\u00f1ez-Mancera NG, Aguilar-Rojas AM, \u00c1lvarez-Jard\u00f3n AP. Knowledge of bisphosphonate-related osteonecrosis of the jaws among Mexican dentists. Med Oral Patol Oral Cir Bucal. 2017, 22:e84-7. 10.4317\/medoral.21433","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2022.02.008","article-title":"American Association of Oral and Maxillofacial Surgeons' position paper on medication-related osteonecrosis of the jaws-2022 update","volume":"80","author":"Ruggiero SL","year":"2022","unstructured":"Ruggiero SL, Dodson TB, Aghaloo T, Carlson ER, Ward BB, Kademani D. American Association of Oral and Maxillofacial Surgeons' position paper on medication-related osteonecrosis of the jaws-2022 update. J Oral Maxillofac Surg. 2022, 80:920-43. 10.1016\/j.joms.2022.02.008","journal-title":"J Oral Maxillofac Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.04.031","article-title":"American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update","volume":"72","author":"Ruggiero SL","year":"2014","unstructured":"Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, O'Ryan F. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update. J Oral Maxillofac Surg. 2014, 72:1938-56. 10.1016\/j.joms.2014.04.031","journal-title":"J Oral Maxillofac Surg"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.01.009","article-title":"American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws--2009 update","volume":"67","author":"Ruggiero SL","year":"2009","unstructured":"Ruggiero SL, Dodson TB, Assael LA, Landesberg R, Marx RE, Mehrotra B. American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws--2009 update. J Oral Maxillofac Surg. 2009, 67:2-12. 10.1016\/j.joms.2009.01.009","journal-title":"J Oral Maxillofac Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0278-2391(03)00720-1","article-title":"Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic","volume":"61","author":"Marx RE","year":"2003","unstructured":"Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg. 2003, 61:1115-7. 10.1016\/s0278-2391(03)00720-1","journal-title":"J Oral Maxillofac Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2007.0346","article-title":"Denture-related osteonecrosis of the maxilla associated with oral bisphosphonate treatment","volume":"138","author":"Levin L","year":"2007","unstructured":"Levin L, Laviv A, Schwartz-Arad D. Denture-related osteonecrosis of the maxilla associated with oral bisphosphonate treatment. J Am Dent Assoc. 2007, 138:1218-20. 10.14219\/jada.archive.2007.0346","journal-title":"J Am Dent Assoc"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21380","article-title":"Successful treatment of advanced bisphosphonate-related osteonecrosis of the mandible with adjunctive teriparatide therapy","volume":"33","author":"Lee JJ","year":"2011","unstructured":"Lee JJ, Cheng SJ, Jeng JH, Chiang CP, Lau HP, Kok SH. Successful treatment of advanced bisphosphonate-related osteonecrosis of the mandible with adjunctive teriparatide therapy. Head Neck. 2011, 33:1366-71. 10.1002\/hed.21380","journal-title":"Head Neck"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2010.02.037","article-title":"Oral bisphosphonate-associated osteonecrosis of the jaw after implant surgery: a case report and literature review","volume":"68","author":"Bedogni A","year":"2010","unstructured":"Bedogni A, Bettini G, Totola A, Saia G, Nocini PF. Oral bisphosphonate-associated osteonecrosis of the jaw after implant surgery: a case report and literature review. J Oral Maxillofac Surg. 2010, 68:1662-6. 10.1016\/j.joms.2010.02.037","journal-title":"J Oral Maxillofac Surg"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1563\/aaid-joi-D-18-00254","article-title":"Treatment of bisphosphonate-related osteonecrosis of the jaw with plasma rich in growth factors after dental implant surgery: a case report","volume":"45","author":"Gil IG","year":"2019","unstructured":"Gil IG, Ponte BM, Mateo ST, Garc\u00eda JJ. Treatment of bisphosphonate-related osteonecrosis of the jaw with plasma rich in growth factors after dental implant surgery: a case report. J Oral Implantol. 2019, 45:289-96. 10.1563\/aaid-joi-D-18-00254","journal-title":"J Oral Implantol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4103\/ejd.ejd_264_16","article-title":"A case of tooth fracture occurred upon medicating bisphosphonate for an elderly person: preservation therapy and responses for stage 0 of bisphosphonate-related osteonecrosis of jaw","volume":"11","author":"Suzuki N","year":"2017","unstructured":"Suzuki N, Oguchi H, Yamauchi Y, Karube Y, Suzuki Y, Hosoya N. A case of tooth fracture occurred upon medicating bisphosphonate for an elderly person: preservation therapy and responses for stage 0 of bisphosphonate-related osteonecrosis of jaw. Eur J Dent. 2017, 11:258-63. 10.4103\/ejd.ejd_264_16","journal-title":"Eur J Dent"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.04.051","article-title":"Bisphosphonate-related osteonecrosis of the jaw: clinical features, risk factors, management, and treatment outcomes of 26 patients","volume":"67","author":"Thumbigere-Math V","year":"2009","unstructured":"Thumbigere-Math V, Sabino MC, Gopalakrishnan R, et al.. Bisphosphonate-related osteonecrosis of the jaw: clinical features, risk factors, management, and treatment outcomes of 26 patients. J Oral Maxillofac Surg. 2009, 67:1904-13. 10.1016\/j.joms.2009.04.051","journal-title":"J Oral Maxillofac Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2019.03.006","article-title":"Serum C-terminal cross-linking telopeptide level as a predictive biomarker of osteonecrosis after dentoalveolar surgery in patients receiving bisphosphonate therapy: systematic review and meta-analysis","volume":"150","author":"Awad ME","year":"2019","unstructured":"Awad ME, Sun C, Jernigan J, Elsalanty M. Serum C-terminal cross-linking telopeptide level as a predictive biomarker of osteonecrosis after dentoalveolar surgery in patients receiving bisphosphonate therapy: systematic review and meta-analysis. J Am Dent Assoc. 2019, 150:664-675.e8. 10.1016\/j.adaj.2019.03.006","journal-title":"J Am Dent Assoc"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2007.08.008","article-title":"A review of the literature on osteonecrosis of the jaw in patients with osteoporosis treated with oral bisphosphonates: prevalence, risk factors, and clinical characteristics","volume":"29","author":"Pazianas M","year":"2007","unstructured":"Pazianas M, Miller P, Blumentals WA, Bernal M, Kothawala P. A review of the literature on osteonecrosis of the jaw in patients with osteoporosis treated with oral bisphosphonates: prevalence, risk factors, and clinical characteristics. Clin Ther. 2007, 29:1548-58. 10.1016\/j.clinthera.2007.08.008","journal-title":"Clin Ther"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.5125\/jkaoms.2018.44.5.225","article-title":"Clinical characteristics and recurrence-related factors of medication-related osteonecrosis of the jaw","volume":"44","author":"Kang MH","year":"2018","unstructured":"Kang MH, Lee DK, Kim CW, Song IS, Jun SH. Clinical characteristics and recurrence-related factors of medication-related osteonecrosis of the jaw. J Korean Assoc Oral Maxillofac Surg. 2018, 44:225-31. 10.5125\/jkaoms.2018.44.5.225","journal-title":"J Korean Assoc Oral Maxillofac Surg"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012432.pub2","article-title":"Interventions for managing medication-related osteonecrosis of the jaw","volume":"10","author":"Beth-Tasdogan NH","year":"2017","unstructured":"Beth-Tasdogan NH, Mayer B, Hussein H, Zolk O. Interventions for managing medication-related osteonecrosis of the jaw. Cochrane Database Syst Rev. 2017, 10:CD012432. 10.1002\/14651858.CD012432.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.4103\/2231-0762.178742","article-title":"Medication-related osteonecrosis of the jaw: clinical and practical guidelines","volume":"6","author":"Rosella D","year":"2016","unstructured":"Rosella D, Papi P, Giardino R, Cicalini E, Piccoli L, Pompa G. Medication-related osteonecrosis of the jaw: clinical and practical guidelines. J Int Soc Prev Community Dent. 2016, 6:97-104. 10.4103\/2231-0762.178742","journal-title":"J Int Soc Prev Community Dent"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.9-90004-28","article-title":"Safety of intravenous and oral bisphosphonates and compliance with dosing regimens","volume":"9","author":"Conte P","year":"2004","unstructured":"Conte P, Guarneri V. Safety of intravenous and oral bisphosphonates and compliance with dosing regimens. Oncologist. 2004, 9:28-37. 10.1634\/theoncologist.9-90004-28","journal-title":"Oncologist"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.12.040","article-title":"Knowledge, practices, and opinions of ontario dentists when treating patients receiving bisphosphonates","volume":"73","author":"Alhussain A","year":"2015","unstructured":"Alhussain A, Peel S, Dempster L, Clokie C, Azarpazhooh A. Knowledge, practices, and opinions of ontario dentists when treating patients receiving bisphosphonates. J Oral Maxillofac Surg. 2015, 73:1095-105. 10.1016\/j.joms.2014.12.040","journal-title":"J Oral Maxillofac Surg"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-015-2689-6","article-title":"Knowledge and attitudes of Brazilian dental students and dentists regarding bisphosphonate-related osteonecrosis of the jaw","volume":"23","author":"de Lima PB","year":"2015","unstructured":"de Lima PB, Brasil VL, de Castro JF, de Moraes Ramos-Perez FM, Alves FA, dos Anjos Pontual ML, da Cruz Perez DE. Knowledge and attitudes of Brazilian dental students and dentists regarding bisphosphonate-related osteonecrosis of the jaw. Support Care Cancer. 2015, 23:3421-6. 10.1007\/s00520-015-2689-6","journal-title":"Support Care Cancer"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2020.12.012","article-title":"Dental practitioners' and students' knowledge of medication related osteonecrosis of the jaw (MRONJ)","volume":"29","author":"Almousa MA","year":"2021","unstructured":"Almousa MA, Alharbi GK, Alqahtani AS, Chachar Y, Alkadi L, Aboalela A. Dental practitioners' and students' knowledge of medication related osteonecrosis of the jaw (MRONJ). Saudi Pharm J. 2021, 29:96-103. 10.1016\/j.jsps.2020.12.012","journal-title":"Saudi Pharm J"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e04321","article-title":"Dentists' knowledge about medication-related osteonecrosis of the jaw and its management","volume":"6","author":"Al-Eid R","year":"2020","unstructured":"Al-Eid R, Alduwayan T, Bin Khuthaylah M, Al Shemali M. Dentists' knowledge about medication-related osteonecrosis of the jaw and its management. Heliyon. 2020, 6:e04321. 10.1016\/j.heliyon.2020.e04321","journal-title":"Heliyon"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1701542","article-title":"Knowledge and opinions of Saudi dentists regarding dental treatment of patients undergoing bisphosphonates","volume":"14","author":"Al-Maweri SA","year":"2020","unstructured":"Al-Maweri SA, Alshammari MN, Alharbi AR, et al.. Knowledge and opinions of Saudi dentists regarding dental treatment of patients undergoing bisphosphonates. Eur J Dent. 2020, 14:144-51. 10.1055\/s-0040-1701542","journal-title":"Eur J Dent"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3290\/j.ohpd.a43361","article-title":"Awareness about medication-related osteonecrosis of the jaw among dental professionals: a multicentre study","volume":"18","author":"Patil V","year":"2020","unstructured":"Patil V, Acharya S, Vineetha R, Nikhil K. Awareness about medication-related osteonecrosis of the jaw among dental professionals: a multicentre study. Oral Health Prev Dent. 2020, 18:505-9. 10.3290\/j.ohpd.a43361","journal-title":"Oral Health Prev Dent"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.4103\/ejd.ejd_27_17","article-title":"Dental students' knowledge of medication-related osteonecrosis of the jaw","volume":"11","author":"Rosella D","year":"2017","unstructured":"Rosella D, Papi P, Pompa G, Capogreco M, De Angelis F, Di Carlo S. Dental students' knowledge of medication-related osteonecrosis of the jaw. Eur J Dent. 2017, 11:461-8. 10.4103\/ejd.ejd_27_17","journal-title":"Eur J Dent"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2753.2009.01203.x","article-title":"Bisphosphonate-associated osteonecrosis of the jaw. Knowledge and attitudes of dentists and dental students: a preliminary study","volume":"16","author":"L\u00f3pez-Jornet P","year":"2010","unstructured":"L\u00f3pez-Jornet P, Camacho-Alonso F, Molina-Mi\u00f1ano F, Gomez-Garcia F. Bisphosphonate-associated osteonecrosis of the jaw. Knowledge and attitudes of dentists and dental students: a preliminary study. J Eval Clin Pract. 2010, 16:878-82. 10.1111\/j.1365-2753.2009.01203.x","journal-title":"J Eval Clin Pract"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/214685-knowledge-of-dental-students-and-practitioners-about-medication-related-osteonecrosis-of-the-jaw-in-the-central-region-of-saudi-arabia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:11:49Z","timestamp":1707509509000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/214685-knowledge-of-dental-students-and-practitioners-about-medication-related-osteonecrosis-of-the-jaw-in-the-central-region-of-saudi-arabia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,12]]},"references-count":27,"URL":"https:\/\/doi.org\/10.7759\/cureus.52165","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1,12]]}}}