{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T08:23:54Z","timestamp":1773735834391,"version":"3.50.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,14]]},"DOI":"10.7759\/cureus.52261","type":"journal-article","created":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T17:22:20Z","timestamp":1705252940000},"source":"Crossref","is-referenced-by-count":4,"title":["Semi-Immersive Virtual Reality Exercise Therapy for Upper Limb Rehabilitation in Patients With Spinal Cord Injury Using the Leap Motion Controller"],"prefix":"10.7759","author":[{"given":"Moaied Mohamed Ahmed","family":"Al Nattah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Tiberti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leandro","family":"Segaletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Anatomy and physiology of the spinal cord. In: Transplantation of neural tissue into the spinal cord","author":"Antal N","year":"2006","unstructured":"Antal N, Gerta V. Anatomy and physiology of the spinal cord. In: Transplantation of neural tissue into the spinal cord. Springer, Boston, MA; 2006. 1-23."},{"key":"ref2","article-title":"","author":"Snell RS","year":"2010","unstructured":"Snell RS. Clinical Neuroanatomy. Wolters Kluwer Health\/Lippincott Williams & Wilkins, Philadelphia; 2010. https:\/\/books.google.it\/books\/about\/Clinical_Neuroanatomy.html?id=ABPmvroyrD0C&redir_esc=y."},{"key":"ref3","article-title":"Spinal Injury: Assessment and Initial Management","author":"National Clinical Guideline Centre","year":"2016","unstructured":"National Clinical Guideline Centre. Spinal Injury: Assessment and Initial Management. Spinal Cord Decompression National Institute for Health and Care Excellence (NICE). London; 2016."},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS-D-15-00697","article-title":"Joint contractures resulting from prolonged immobilization: etiology, prevention, and management","volume":"25","author":"Born CT","year":"2017","unstructured":"Born CT, Gil JA, Goodman AD. Joint contractures resulting from prolonged immobilization: etiology, prevention, and management. J Am Acad Orthop Surg. 2017, 25:110-6. 10.5435\/JAAOS-D-15-00697","journal-title":"J Am Acad Orthop Surg"},{"key":"ref5","article-title":"National Guideline Alliance (UK). Physical interventions for people with complex rehabilitations needs after traumatic injury: Rehabilitation after traumatic injury: Evidence review B.1. London: National Institute for Health and Care Excellence","year":"2022","unstructured":"National Guideline Alliance (UK). Physical interventions for people with complex rehabilitations needs after traumatic injury. Rehabilitation after traumatic injury: Evidence review B.1. London: National Institute for Health and Care Excellence. NICE. 2022,","journal-title":"NICE"},{"key":"ref6","article-title":"Environments and system types of virtual reality technology in STEM: A survey","volume":"8","author":"Asmaa Saeed","year":"2017","unstructured":"Asmaa Saeed, et al.. Environments and system types of virtual reality technology in STEM: A survey. Inter Jr Adv Com Sci App. 2017, 8:6.","journal-title":"Inter Jr Adv Com Sci App"},{"key":"ref7","article-title":"Unity 3D game development by example: A Seat-of-your-pants manual for building fun, groovy little games quickly","author":"CREIGHTON","year":"2010","unstructured":"CREIGHTON, Ryan Henson. Unity 3D game development by example: A Seat-of-your-pants manual for building fun, groovy little games quickly. Packt Publishing Ltd. 2010,","journal-title":"Packt Publishing Ltd"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/s21062065","article-title":"Leap motion controller video game-based therapy for upper extremity motor recovery in patients with central nervous system diseases. a systematic review with meta-analysis","volume":"21","author":"Cort\u00e9s-P\u00e9rez I","year":"2021","unstructured":"Cort\u00e9s-P\u00e9rez I, Zagalaz-Anula N, Montoro-C\u00e1rdenas D, Lomas-Vega R, Obrero-Gait\u00e1n E, Osuna-P\u00e9rez MC. Leap motion controller video game-based therapy for upper extremity motor recovery in patients with central nervous system diseases. a systematic review with meta-analysis. Sensors (Basel). 2021, 21:10.3390\/s21062065","journal-title":"Sensors (Basel)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6639762","article-title":"Intraoperative quantitative measurements for bradykinesia evaluation during deep brain stimulation surgery using leap motion controller: a pilot study","volume":"2021","author":"Wu J","year":"2021","unstructured":"Wu J, Yu N, Yu Y, et al.. Intraoperative quantitative measurements for bradykinesia evaluation during deep brain stimulation surgery using leap motion controller: a pilot study. Parkinsons Dis. 2021, 2021:6639762. 10.1155\/2021\/6639762","journal-title":"Parkinsons Dis"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s12938-018-0600-7","article-title":"Objective and automatic classification of Parkinson disease with Leap Motion controller","volume":"17","author":"Butt AH","year":"2018","unstructured":"Butt AH, Rovini E, Dolciotti C, De Petris G, Bongioanni P, Carboncini MC, Cavallo F. Objective and automatic classification of Parkinson disease with Leap Motion controller. Biomed Eng Online. 2018, 17:168. 10.1186\/s12938-018-0600-7","journal-title":"Biomed Eng Online"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.716102","article-title":"Towards objective quantification of hand tremors and bradykinesia using contactless sensors: a systematic review","volume":"13","author":"Garcia-Agundez A","year":"2021","unstructured":"Garcia-Agundez A, Eickhoff C. Towards objective quantification of hand tremors and bradykinesia using contactless sensors: a systematic review. Front Aging Neurosci. 2021, 13:716102. 10.3389\/fnagi.2021.716102","journal-title":"Front Aging Neurosci"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s12984-019-0601-1","article-title":"Advantages of using 3D virtual reality based training in persons with Parkinson's disease: a parallel study","volume":"16","author":"Cikajlo I","year":"2019","unstructured":"Cikajlo I, Peterlin Potisk K. Advantages of using 3D virtual reality based training in persons with Parkinson's disease: a parallel study. J Neuroeng Rehabil. 2019, 16:119. 10.1186\/s12984-019-0601-1","journal-title":"J Neuroeng Rehabil"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jht.2019.03.012","article-title":"Leap Motion Controller-based training for upper extremity rehabilitation in children and adolescents with physical disabilities: A randomized controlled trial","volume":"33","author":"Tarakci E","year":"2020","unstructured":"Tarakci E, Arman N, Tarakci D, Kasapcopur O. Leap Motion Controller-based training for upper extremity rehabilitation in children and adolescents with physical disabilities: A randomized controlled trial. J Hand Ther. 2020, 33:220-228.e1. 10.1016\/j.jht.2019.03.012","journal-title":"J Hand Ther"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.219043","article-title":"Leap Motion-based virtual reality training for improving motor functional recovery of upper limbs and neural reorganization in subacute stroke patients","volume":"12","author":"Wang ZR","year":"2017","unstructured":"Wang ZR, Wang P, Xing L, Mei LP, Zhao J, Zhang T. Leap Motion-based virtual reality training for improving motor functional recovery of upper limbs and neural reorganization in subacute stroke patients. Neural Regen Res. 2017, 12:1823-31. 10.4103\/1673-5374.219043","journal-title":"Neural Regen Res"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2196\/11925","article-title":"Use of commercial off-the-shelf devices for the detection of manual gestures in surgery: systematic literature review","volume":"21","author":"Alvarez-Lopez F","year":"2019","unstructured":"Alvarez-Lopez F, Maina MF, Saig\u00ed-Rubi\u00f3 F. Use of commercial off-the-shelf devices for the detection of manual gestures in surgery: systematic literature review. J Med Internet Res. 2019, 21:e11925. 10.2196\/11925","journal-title":"J Med Internet Res"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s12984-020-00718-x","article-title":"Effects of virtual reality associated with serious games for upper limb rehabilitation inpatients with multiple sclerosis: randomized controlled trial","volume":"17","author":"Cuesta-G\u00f3mez A","year":"2020","unstructured":"Cuesta-G\u00f3mez A, S\u00e1nchez-Herrera-Baeza P, O\u00f1a-Simba\u00f1a ED, et al.. Effects of virtual reality associated with serious games for upper limb rehabilitation inpatients with multiple sclerosis: randomized controlled trial. J Neuroeng Rehabil. 2020, 17:90. 10.1186\/s12984-020-00718-x","journal-title":"J Neuroeng Rehabil"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0267549","article-title":"A research protocol on leap motion tracking device: A novel intervention method in distal radial fracture rehabilitation","volume":"17","author":"Arora SP","year":"2022","unstructured":"Arora SP, Naqvi WM. A research protocol on leap motion tracking device: A novel intervention method in distal radial fracture rehabilitation. PLoS One. 2022, 17:e0267549. 10.1371\/journal.pone.0267549","journal-title":"PLoS One"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2011.62","article-title":"The effects of exercise training on physical capacity, strength, body composition and functional performance among adults with spinal cord injury: a systematic review","volume":"49","author":"Hicks AL","year":"2011","unstructured":"Hicks AL, Martin Ginis KA, Pelletier CA, Ditor DS, Foulon B, Wolfe DL. The effects of exercise training on physical capacity, strength, body composition and functional performance among adults with spinal cord injury: a systematic review. Spinal Cord. 2011, 49:1103-27. 10.1038\/sc.2011.62","journal-title":"Spinal Cord"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-016-5133-4","article-title":"Classifications in brief: American Spinal Injury Association (ASIA) impairment scale","volume":"475","author":"Roberts TT","year":"2017","unstructured":"Roberts TT, Leonard GR, Cepela DJ. Classifications in brief: American Spinal Injury Association (ASIA) impairment scale. Clin Orthop Relat Res. 2017, 475:1499-504. 10.1007\/s11999-016-5133-4","journal-title":"Clin Orthop Relat Res"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3109\/02844319509034334","article-title":"Sollerman hand function test. A standardised method and its use in tetraplegic patients","volume":"29","author":"Sollerman C","year":"1995","unstructured":"Sollerman C, Ejesk\u00e4r A. Sollerman hand function test. A standardised method and its use in tetraplegic patients. Scand J Plast Reconstr Surg Hand Surg. 1995, 29:167-76. 10.3109\/02844319509034334","journal-title":"Scand J Plast Reconstr Surg Hand Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/219063-semi-immersive-virtual-reality-exercise-therapy-for-upper-limb-rehabilitation-in-patients-with-spinal-cord-injury-using-the-leap-motion-controller","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:14:13Z","timestamp":1707509653000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/219063-semi-immersive-virtual-reality-exercise-therapy-for-upper-limb-rehabilitation-in-patients-with-spinal-cord-injury-using-the-leap-motion-controller"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,14]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.52261","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1,14]]}}}