{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T08:21:15Z","timestamp":1773735675280,"version":"3.50.1"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,27]]},"DOI":"10.7759\/cureus.53043","type":"journal-article","created":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T12:13:46Z","timestamp":1706357626000},"source":"Crossref","is-referenced-by-count":1,"title":["Acute Encephalopathy in a 10-Year-Old Patient With Maple Syrup Urine Disease: A Challenging Diagnosis"],"prefix":"10.7759","author":[{"given":"Pedro","family":"Miragaia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Grangeia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esmeralda","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augusto","family":"Ribeiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000032174","article-title":"Neonatal maple syrup urine disease case report and literature review","volume":"101","author":"Liu Q","year":"2022","unstructured":"Liu Q, Li F, Zhou J, Liu X, Peng J, Gong L. Neonatal maple syrup urine disease case report and literature review. Medicine (Baltimore). 2022, 101:e32174. 10.1097\/MD.0000000000032174","journal-title":"Medicine (Baltimore)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12113797","article-title":"Acute encephalopathy caused by inherited metabolic diseases","volume":"12","author":"Sugiyama Y","year":"2023","unstructured":"Sugiyama Y, Murayama K. Acute encephalopathy caused by inherited metabolic diseases. J Clin Med. 2023, 12:3797. 10.3390\/jcm12113797","journal-title":"J Clin Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.351031","article-title":"Tissue-specific and nutrient regulation of the branched-chain \u03b1-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm)","volume":"287","author":"Zhou M","year":"2012","unstructured":"Zhou M, Lu G, Gao C, Wang Y, Sun H. Tissue-specific and nutrient regulation of the branched-chain \u03b1-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). J Biol Chem. 2012, 287:23397-406. 10.1074\/jbc.M112.351031","journal-title":"J Biol Chem"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2020.08.001","article-title":"Guidelines for the diagnosis and treatment of acute encephalopathy in childhood","volume":"43","author":"Mizuguchi M","year":"2021","unstructured":"Mizuguchi M, Ichiyama T, Imataka G, et al.. Guidelines for the diagnosis and treatment of acute encephalopathy in childhood. Brain Dev. 2021, 43:2-31. 10.1016\/j.braindev.2020.08.001","journal-title":"Brain Dev"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2147\/TACG.S125962","article-title":"Maple syrup urine disease: mechanisms and management","volume":"10","author":"Blackburn PR","year":"2017","unstructured":"Blackburn PR, Gass JM, Vairo FP, et al.. Maple syrup urine disease: mechanisms and management. Appl Clin Genet. 2017, 10:57-66. 10.2147\/TACG.S125962","journal-title":"Appl Clin Genet"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X231183981","article-title":"Metabolic crisis in maple syrup urine disease: an unusual complication of a rare disease: a case report","volume":"52","author":"Doshi HP","year":"2024","unstructured":"Doshi HP, Vachharajani HH, Tchan MC, Nasreddine MA, Billmore KE. Metabolic crisis in maple syrup urine disease: an unusual complication of a rare disease: a case report. Anaesth Intensive Care. 2024, 52:64-8. 10.1177\/0310057X231183981","journal-title":"Anaesth Intensive Care"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11195921","article-title":"A comprehensive review of pediatric acute encephalopathy","volume":"11","author":"Imataka G","year":"2022","unstructured":"Imataka G, Kuwashima S, Yoshihara S. A comprehensive review of pediatric acute encephalopathy. J Clin Med. 2022, 11:5921. 10.3390\/jcm11195921","journal-title":"J Clin Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2009.11.010","article-title":"Maple syrup urine disease: further evidence that newborn screening may fail to identify variant forms","volume":"100","author":"Puckett RL","year":"2010","unstructured":"Puckett RL, Lorey F, Rinaldo P, et al.. Maple syrup urine disease: further evidence that newborn screening may fail to identify variant forms. Mol Genet Metab. 2010, 100:136-42. 10.1016\/j.ymgme.2009.11.010","journal-title":"Mol Genet Metab"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-006-0276-1","article-title":"Variant maple syrup urine disease (MSUD)\u2014the entire spectrum","volume":"29","author":"Simon E","year":"2006","unstructured":"Simon E, Flaschker N, Schadewaldt P, Langenbeck U, Wendel U. Variant maple syrup urine disease (MSUD)\u2014the entire spectrum. J Inherit Metab Dis. 2006, 29:716-24. 10.1007\/s10545-006-0276-1","journal-title":"J Inherit Metab Dis"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-0427","article-title":"Intermittent maple syrup urine disease: two case reports","volume":"133","author":"Axler O","year":"2014","unstructured":"Axler O, Holmquist P. Intermittent maple syrup urine disease: two case reports. Pediatrics. 2014, 133:e458-60. 10.1542\/peds.2013-0427","journal-title":"Pediatrics"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v11.i5.1077","article-title":"Diagnosis of an intermediate case of maple syrup urine disease: a case report","volume":"11","author":"Lin YT","year":"2023","unstructured":"Lin YT, Cai YN, Ting TH, et al.. Diagnosis of an intermediate case of maple syrup urine disease: a case report. World J Clin Cases. 2023, 11:1077-85. 10.12998\/wjcc.v11.i5.1077","journal-title":"World J Clin Cases"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/217876-acute-encephalopathy-in-a-10-year-old-patient-with-maple-syrup-urine-disease-a-challenging-diagnosis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T20:14:11Z","timestamp":1707509651000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/217876-acute-encephalopathy-in-a-10-year-old-patient-with-maple-syrup-urine-disease-a-challenging-diagnosis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,27]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.53043","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1,27]]}}}