{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T16:40:36Z","timestamp":1787157636981,"version":"build-2736575974"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,16]]},"DOI":"10.7759\/cureus.54285","type":"journal-article","created":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T10:43:09Z","timestamp":1708080189000},"source":"Crossref","is-referenced-by-count":1,"title":["The Anesthetic Complexity of Eisenmenger Syndrome: A Clinical Case"],"prefix":"10.7759","author":[{"given":"R\u00faben","family":"Calaia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neuza","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Branquinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduarda","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Guedes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.01.022","article-title":"Eisenmenger syndrome: JACC state-of-the-art review","volume":"79","author":"Arvanitaki A","year":"2022","unstructured":"Arvanitaki A, Gatzoulis MA, Opotowsky AR, et al.. Eisenmenger syndrome: JACC state-of-the-art review. J Am Coll Cardiol. 2022, 79:1183-98. 10.1016\/j.jacc.2022.01.022","journal-title":"J Am Coll Cardiol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.119142","article-title":"Case series: dexmedetomidine and ketamine for anesthesia in patients with uncorrected congenital cyanotic heart disease presenting for non-cardiac surgery","volume":"29","author":"Goyal R","year":"2013","unstructured":"Goyal R, Singh S, Bangi A, Singh SK. Case series: dexmedetomidine and ketamine for anesthesia in patients with uncorrected congenital cyanotic heart disease presenting for non-cardiac surgery. J Anaesthesiol Clin Pharmacol. 2013, 29:543-6. 10.4103\/0970-9185.119142","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/s0750-7658(05)80390-9","article-title":"Effects of mechanical ventilation with PEEP on right to left intra-cardiac shunt caused by patent foramen ovale","volume":"14","author":"V\u00e9drinne JM","year":"1995","unstructured":"V\u00e9drinne JM, Duperret S, Gratadour P, Barth\u00e9l\u00e9my C, Motin J. Effects of mechanical ventilation with PEEP on right to left intra-cardiac shunt caused by patent foramen ovale. Ann Fr Anesth Reanim. 1995, 14:387-92. 10.1016\/s0750-7658(05)80390-9","journal-title":"Ann Fr Anesth Reanim"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjane.2021.02.020","article-title":"Dexmedetomidine reduces postoperative cognitive and behavioral dysfunction in adults submitted to general anesthesia for non-cardiac surgery: meta-analysis of randomized clinical trials","volume":"71","author":"Gov\u00eaia CS","year":"2021","unstructured":"Gov\u00eaia CS, Miranda DB, Oliveira LV, Praxedes FB, Moreira LG, Guimar\u00e3es GM. Dexmedetomidine reduces postoperative cognitive and behavioral dysfunction in adults submitted to general anesthesia for non-cardiac surgery: meta-analysis of randomized clinical trials. Braz J Anesthesiol. 2021, 71:413-20. 10.1016\/j.bjane.2021.02.020","journal-title":"Braz J Anesthesiol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpaic.2010.12.010","article-title":"Intravenous anaesthetic agents","volume":"12","author":"Pandit J","year":"2011","unstructured":"Pandit J. Intravenous anaesthetic agents. Anaesth Intensive Care Med. 2011, 12:144-150. 10.1016\/j.mpaic.2010.12.010","journal-title":"Anaesth Intensive Care Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/0885066616689555","article-title":"Dexmedetomidine for refractory intracranial hypertension","volume":"34","author":"Schomer KJ","year":"2019","unstructured":"Schomer KJ, Sebat CM, Adams JY, Duby JJ, Shahlaie K, Louie EL. Dexmedetomidine for refractory intracranial hypertension. J Intensive Care Med. 2019, 34:62-6. 10.1177\/0885066616689555","journal-title":"J Intensive Care Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-017-0507-7","article-title":"Clinical pharmacokinetics and pharmacodynamics of dexmedetomidine","volume":"56","author":"Weerink MA","year":"2017","unstructured":"Weerink MA, Struys MM, Hannivoort LN, Barends CR, Absalom AR, Colin P. Clinical pharmacokinetics and pharmacodynamics of dexmedetomidine. Clin Pharmacokinet. 2017, 56:893-913. 10.1007\/s40262-017-0507-7","journal-title":"Clin Pharmacokinet"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4097\/kja.19259","article-title":"Dexmedetomidine: present and future directions","volume":"72","author":"Lee S","year":"2019","unstructured":"Lee S. Dexmedetomidine: present and future directions. Korean J Anesthesiol. 2019, 72:323-30. 10.4097\/kja.19259","journal-title":"Korean J Anesthesiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-018-1455-1","article-title":"Dexmedetomidine attenuates lung apoptosis induced by renal ischemia-reperfusion injury through \u03b1(2)AR\/PI3K\/Akt pathway","volume":"16","author":"Li J","year":"2018","unstructured":"Li J, Chen Q, He X, et al.. Dexmedetomidine attenuates lung apoptosis induced by renal ischemia-reperfusion injury through \u03b1(2)AR\/PI3K\/Akt pathway. J Transl Med. 2018, 16:78. 10.1186\/s12967-018-1455-1","journal-title":"J Transl Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-023-03261-w","article-title":"Dexmedetomidine as a cardioprotective drug: a narrative review","volume":"37","author":"Takahashi K","year":"2023","unstructured":"Takahashi K, Yoshikawa Y, Kanda M, Hirata N, Yamakage M. Dexmedetomidine as a cardioprotective drug: a narrative review. J Anesth. 2023, 37:961-70. 10.1007\/s00540-023-03261-w","journal-title":"J Anesth"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/230096-the-anesthetic-complexity-of-eisenmenger-syndrome-a-clinical-case","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T10:43:11Z","timestamp":1708080191000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/230096-the-anesthetic-complexity-of-eisenmenger-syndrome-a-clinical-case"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,16]]},"references-count":10,"URL":"https:\/\/doi.org\/10.7759\/cureus.54285","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2,16]]}}}