{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T01:26:28Z","timestamp":1776821188835,"version":"3.51.2"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,26]]},"DOI":"10.7759\/cureus.54968","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T20:08:35Z","timestamp":1708978115000},"source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and Impact of Thyroid Dysfunction in Patients With Chronic Pulmonary Obstructive Pulmonary Disorder: A Systematic Review and Meta-Analysis"],"prefix":"10.7759","author":[{"given":"Divine Besong","family":"Arrey Agbor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moulika","family":"Kari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel Chandra Harika","family":"Chukka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manisha","family":"Guntha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aung K","family":"Zin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandipkumar S","family":"Chaudhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sai Kumar","family":"Kurva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adil","family":"Amin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00063198-200203000-00001","article-title":"Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines for chronic obstructive pulmonary disease","volume":"8","author":"G\u00f3mez FP","year":"2002","unstructured":"G\u00f3mez FP, Rodriguez-Roisin R. Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines for chronic obstructive pulmonary disease. Curr Opin Pulm Med. 2002, 8:81-6. 10.1097\/00063198-200203000-00001","journal-title":"Curr Opin Pulm Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-013-9537-6","article-title":"COPD and thyroid dysfunctions","volume":"192","author":"Terzano C","year":"2014","unstructured":"Terzano C, Romani S, Paone G, Conti V, Oriolo F. COPD and thyroid dysfunctions. Lung. 2014, 192:103-9. 10.1007\/s00408-013-9537-6","journal-title":"Lung"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00103708","article-title":"Endocrinological derangements in COPD","volume":"34","author":"Laghi F","year":"2009","unstructured":"Laghi F, Adiguzel N, Tobin MJ. Endocrinological derangements in COPD. Eur Respir J. 2009, 34:975-96. 10.1183\/09031936.00103708","journal-title":"Eur Respir J"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.6.2165","article-title":"Hormones and breathing","volume":"122","author":"Saaresranta T","year":"2002","unstructured":"Saaresranta T, Polo O. Hormones and breathing. Chest. 2002, 122:2165-82. 10.1378\/chest.122.6.2165","journal-title":"Chest"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(11)70005-1","article-title":"Neurological and endocrinological disorders: orphans in chronic obstructive pulmonary disease","volume":"105 Suppl 1","author":"Doehner W","year":"2011","unstructured":"Doehner W, Haeusler KG, Endres M, Anker SD, MacNee W, Lainscak M. Neurological and endocrinological disorders: orphans in chronic obstructive pulmonary disease. Respir Med. 2011, 105 Suppl 1:S12-9. 10.1016\/S0954-6111(11)70005-1","journal-title":"Respir Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_84_17","article-title":"Prevalence of thyroid dysfunction in chronic obstructive pulmonary disease patients in a tertiary care center in North India","volume":"7","author":"Chaudhary SC","year":"2018","unstructured":"Chaudhary SC, Ahmad T, Usman K, Sawlani KK, Gupta KK, Verma AK, Reddy DH. Prevalence of thyroid dysfunction in chronic obstructive pulmonary disease patients in a tertiary care center in North India. J Family Med Prim Care. 2018, 7:584-8. 10.4103\/jfmpc.jfmpc_84_17","journal-title":"J Family Med Prim Care"},{"key":"ref7","article-title":"Evaluation of thyroid dysfunction in chronic obstructive pulmonary disease","volume":"24","author":"Gupta M","year":"2013","unstructured":"Gupta M, Vardey SK, Joshi N, Dixit R. Evaluation of thyroid dysfunction in chronic obstructive pulmonary disease. Biomed Res (Aligarh). 2013, 24:110-113.","journal-title":"Biomed Res (Aligarh)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-14-11","article-title":"Comorbidity in patients with chronic obstructive pulmonary disease in family practice: a cross sectional study","volume":"14","author":"Garc\u00eda-Olmos L","year":"2013","unstructured":"Garc\u00eda-Olmos L, Alberquilla A, Ayala V, et al.. Comorbidity in patients with chronic obstructive pulmonary disease in family practice: a cross sectional study. BMC Fam Pract. 2013, 14:11. 10.1186\/1471-2296-14-11","journal-title":"BMC Fam Pract"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2007.01.016","article-title":"Correlates of non-thyroidal illness syndrome in chronic obstructive pulmonary disease","volume":"101","author":"Karadag F","year":"2007","unstructured":"Karadag F, Ozcan H, Karul AB, Yilmaz M, Cildag O. Correlates of non-thyroidal illness syndrome in chronic obstructive pulmonary disease. Respir Med. 2007, 101:1439-46. 10.1016\/j.rmed.2007.01.016","journal-title":"Respir Med"},{"key":"ref10","article-title":"Thyroid disease in the elderly: sex-related differences in clinical expression","volume":"28","author":"Morganti S","year":"2005","unstructured":"Morganti S, Ceda GP, Saccani M, et al.. Thyroid disease in the elderly: sex-related differences in clinical expression. J Endocrinol Invest. 2005, 28:101-4.","journal-title":"J Endocrinol Invest"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/thx.42.7.520","article-title":"Thyroid function and endocrine abnormalities in elderly patients with severe chronic obstructive lung disease","volume":"42","author":"Gow SM","year":"1987","unstructured":"Gow SM, Seth J, Beckett GJ, Douglas G. Thyroid function and endocrine abnormalities in elderly patients with severe chronic obstructive lung disease. Thorax. 1987, 42:520-5. 10.1136\/thx.42.7.520","journal-title":"Thorax"},{"key":"ref12","article-title":"Thyroid dysfunction in exacerbation of chronic obstructive pulmonary disease","volume":"34","author":"Bah\u00e7ecio\u011flu SN","year":"2023","unstructured":"Bah\u00e7ecio\u011flu SN, Ko\u00e7 EM, Akkale TK, Yal\u00e7in MM, K\u00f6kt\u00fcrk N. Thyroid dysfunction in exacerbation of chronic obstructive pulmonary disease. Gazi Med J. 2023, 34:22-6.","journal-title":"Gazi Med J"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/7479992","article-title":"Thyroid gland disease as a comorbid condition in COPD","volume":"2021","author":"Gumus A","year":"2021","unstructured":"Gumus A, Ozcelik N, Yilmaz Kara B, Ozyurt S, Sahin U. Thyroid gland disease as a comorbid condition in COPD. Pulm Med. 2021, 2021:7479992. 10.1155\/2021\/7479992","journal-title":"Pulm Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S291807","article-title":"Association between thyroid function and acute exacerbation of chronic obstructive pulmonary disease","volume":"16","author":"Huang D","year":"2021","unstructured":"Huang D, Wu D, He J, Chen M, Zhao X, Li D, Wu B. Association between thyroid function and acute exacerbation of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2021, 16:333-9. 10.2147\/COPD.S291807","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref15","article-title":"Prevalence of thyroid dysfunction in moderate to severe chronic obstructive pulmonary disease patients - a cross-sectional study","volume":"9","author":"Sebasan RV","year":"2021","unstructured":"Sebasan RV, Baliga KV. Prevalence of thyroid dysfunction in moderate to severe chronic obstructive pulmonary disease patients - a cross-sectional study. Int J Sci Study. 2021, 9:160-3.","journal-title":"Int J Sci Study"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-8-64","article-title":"Effect of thyroid function on COPD exacerbation frequency: a preliminary study","volume":"8","author":"Sarinc Ulasli S","year":"2013","unstructured":"Sarinc Ulasli S, Bozbas SS, Ozen ZE, Ozyurek BA, Ulubay G. Effect of thyroid function on COPD exacerbation frequency: a preliminary study. Multidiscip Respir Med. 2013, 8:64. 10.1186\/2049-6958-8-64","journal-title":"Multidiscip Respir Med"},{"key":"ref17","article-title":"A study of prevalence of thyroid disorders in chronic obstructive pulmonary disease patients at a tertiary care center in U.P","volume":"3","author":"Singh L","year":"2016","unstructured":"Singh L, Jain A, Agrawal A, Tandon R, Kumar H. A study of prevalence of thyroid disorders in chronic obstructive pulmonary disease patients at a tertiary care center in U.P. Int J Contemp Med Res. 2016, 3:1239-42.","journal-title":"Int J Contemp Med Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.14260\/JEMDS\/2019\/488","article-title":"To study the association of thyroid dysfunction in chronic obstructive pulmonary disease patients (a cross sectional prevalence study single centre only)","volume":"8","author":"Verma S","year":"2019","unstructured":"Verma S, Gautam S, Bhan U, Vohra DK, Gupa A, Mittal S, Singh G. To study the association of thyroid dysfunction in chronic obstructive pulmonary disease patients (a cross sectional prevalence study single centre only). J Evolution Med Dent Sci. 2019, 8:2230-3. 10.14260\/JEMDS\/2019\/488","journal-title":"J Evolution Med Dent Sci"},{"key":"ref19","article-title":"Evaluation of thyroid functions in chronic obstructive pulmonary disease","volume":"11","author":"Prakash R","year":"2014","unstructured":"Prakash R, Harish M, Suryanarayana V, Padma Priya M, Dharmic S. Evaluation of thyroid functions in chronic obstructive pulmonary disease. World J Med Sci. 2014, 11:57-8.","journal-title":"World J Med Sci"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.5578\/tt.68257","article-title":"An underestimated comorbidity of COPD: Thyroid dysfunction","volume":"67","author":"Akp\u0131nar EE","year":"2019","unstructured":"Akp\u0131nar EE. An underestimated comorbidity of COPD: Thyroid dysfunction. Tuberk Toraks. 2019, 67:131-5. 10.5578\/tt.68257","journal-title":"Tuberk Toraks"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199003000-00009","article-title":"Hypoxia and hypercarbia of chronic lung disease: minimal effects on anterior pituitary function","volume":"83","author":"Banks WA","year":"1990","unstructured":"Banks WA, Cooper JA. Hypoxia and hypercarbia of chronic lung disease: minimal effects on anterior pituitary function. South Med J. 1990, 83:290-3. 10.1097\/00007611-199003000-00009","journal-title":"South Med J"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1136\/thx.43.11.945-a","article-title":"Thyroid function and endocrine abnormalities in elderly patients with severe chronic obstructive lung disease","volume":"43","author":"Semple PD","year":"1988","unstructured":"Semple PD, Hume R, Beastall GH, Watson WS. Thyroid function and endocrine abnormalities in elderly patients with severe chronic obstructive lung disease. Thorax. 1988, 43:945-6. 10.1136\/thx.43.11.945-a","journal-title":"Thorax"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1053\/meta.2001.28157","article-title":"Effects of severity of chronic obstructive pulmonary disease on thyroid function","volume":"50","author":"Dimopoulou I","year":"2001","unstructured":"Dimopoulou I, Ilias I, Mastorakos G, Mantzos E, Roussos C, Koutras DA. Effects of severity of chronic obstructive pulmonary disease on thyroid function. Metabolism. 2001, 50:1397-401. 10.1053\/meta.2001.28157","journal-title":"Metabolism"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.5578\/tt.67725","article-title":"Does exercise capacity, dyspnea level, or quality of life actually predict mortality in patients with COPD? 8-year follow-up","volume":"67","author":"\u00c7ift\u00e7i F","year":"2019","unstructured":"\u00c7ift\u00e7i F, \u015een E, Akkoca Y\u0131ld\u0131z \u00d6, Saryal S. Does exercise capacity, dyspnea level, or quality of life actually predict mortality in patients with COPD? 8-year follow-up. Tuberk Toraks. 2019, 67:83-91. 10.5578\/tt.67725","journal-title":"Tuberk Toraks"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-49540-z","article-title":"Prevalence and risk factors of thyroid dysfunction in older adults in the community","volume":"9","author":"Diab N","year":"2019","unstructured":"Diab N, Daya NR, Juraschek SP, et al.. Prevalence and risk factors of thyroid dysfunction in older adults in the community. Sci Rep. 2019, 9:13156. 10.1038\/s41598-019-49540-z","journal-title":"Sci Rep"},{"key":"ref26","article-title":"Can impairments of thyroid function test affect prognosis in patients with respiratory failure?","volume":"55","author":"Bacako\u011flu F","year":"2007","unstructured":"Bacako\u011flu F, Ba\u015fo\u011flu OK, G\u00fcrg\u00fcn A, Bayraktar F, Kiran B, Ozhan MH. Can impairments of thyroid function test affect prognosis in patients with respiratory failure?. Tuberk Toraks. 2007, 55:329-35.","journal-title":"Tuberk Toraks"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/230204-prevalence-and-impact-of-thyroid-dysfunction-in-patients-with-chronic-pulmonary-obstructive-pulmonary-disorder-a-systematic-review-and-meta-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T20:08:41Z","timestamp":1708978121000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/230204-prevalence-and-impact-of-thyroid-dysfunction-in-patients-with-chronic-pulmonary-obstructive-pulmonary-disorder-a-systematic-review-and-meta-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,26]]},"references-count":26,"URL":"https:\/\/doi.org\/10.7759\/cureus.54968","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2,26]]}}}