{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T01:51:51Z","timestamp":1778982711047,"version":"3.51.4"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,7]]},"DOI":"10.7759\/cureus.55721","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T14:15:00Z","timestamp":1709820900000},"source":"Crossref","is-referenced-by-count":3,"title":["End-Stage Achalasia With Megaesophagus Refractory to Two Heller Myotomies"],"prefix":"10.7759","author":[{"given":"Lorraine I","family":"Chong Tai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Akil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly Q","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aryama","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.388","article-title":"Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study","volume":"107","author":"von Renteln D","year":"2012","unstructured":"von Renteln D, Inoue H, Minami H, et al.. Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study. Am J Gastroenterol. 2012, 107:411-7. 10.1038\/ajg.2011.388","journal-title":"Am J Gastroenterol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2016.02.039","article-title":"Megaesophagus in achalasia","volume":"351","author":"Maiti A","year":"2016","unstructured":"Maiti A, Bhattacharjee M. Megaesophagus in achalasia. Am J Med Sci. 2016, 351:549. 10.1016\/j.amjms.2016.02.039","journal-title":"Am J Med Sci"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-6-12","article-title":"Gender effect on clinical features of achalasia: a prospective study","volume":"6","author":"Mikaeli J","year":"2006","unstructured":"Mikaeli J, Farrokhi F, Bishehsari F, Mahdavinia M, Malekzadeh R. Gender effect on clinical features of achalasia: a prospective study. BMC Gastroenterol. 2006, 6:12. 10.1186\/1471-230X-6-12","journal-title":"BMC Gastroenterol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1999.035005445.x","article-title":"Inflammatory aetiology of primary oesophageal achalasia: an immunohistochemical and ultrastructural study of Auerbach's plexus","volume":"35","author":"Raymond L","year":"1999","unstructured":"Raymond L, Lach B, Shamji FM. Inflammatory aetiology of primary oesophageal achalasia: an immunohistochemical and ultrastructural study of Auerbach's plexus. Histopathology. 1999, 35:445-53. 10.1046\/j.1365-2559.1999.035005445.x","journal-title":"Histopathology"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.1016\/0003-4975(89)90369-X","article-title":"Esophageal resection for achalasia: indications and results","volume":"47","author":"Orringer MB","year":"1989","unstructured":"Orringer MB, Stirling MC. Esophageal resection for achalasia: indications and results. Ann Thorac Surg. 1989, 47:340-5.","journal-title":"Ann Thorac Surg"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.22516\/25007440.460","article-title":"Megaes\u00f3fago como complicaci\u00f3n de acalasia: reporte de caso y revisi\u00f3n narrativa de la literatura (Article in Spanish)","volume":"4","author":"Rond\u00f3n-Carvajal J","year":"2020","unstructured":"Rond\u00f3n-Carvajal J, Ardila-Hani C, Hani-Ardila A, Vargas-Rubio R, Legu\u00edzamo-Naranjo AM, Ca\u00f1adas-Garrido R, Puentes-Leal G. Megaes\u00f3fago como complicaci\u00f3n de acalasia: reporte de caso y revisi\u00f3n narrativa de la literatura (Article in Spanish). Rev Colomb Gastroenterol. 2020, 4:2021-10. 10.22516\/25007440.460","journal-title":"Rev Colomb Gastroenterol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/2040622317710010","article-title":"Achalasia: current therapeutic options","volume":"8","author":"Arora Z","year":"2017","unstructured":"Arora Z, Thota PN, Sanaka MR. Achalasia: current therapeutic options. Ther Adv Chronic Dis. 2017, 8:101-8. 10.1177\/2040622317710010","journal-title":"Ther Adv Chronic Dis"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.196","article-title":"ACG clinical guideline: diagnosis and management of achalasia","volume":"108","author":"Vaezi MF","year":"2013","unstructured":"Vaezi MF, Pandolfino JE, Vela MF. ACG clinical guideline: diagnosis and management of achalasia. Am J Gastroenterol. 2013, 108:1238-49. 10.1038\/ajg.2013.196","journal-title":"Am J Gastroenterol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.gassur.2006.07.006","article-title":"Long-term results of conventional myotomy in patients with achalasia: a prospective 20-year analysis","volume":"10","author":"Gockel I","year":"2006","unstructured":"Gockel I, Junginger T, Eckardt VF. Long-term results of conventional myotomy in patients with achalasia: a prospective 20-year analysis. J Gastrointest Surg. 2006, 10:1400-8. 10.1016\/j.gassur.2006.07.006","journal-title":"J Gastrointest Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-004-8941-7","article-title":"The laparoscopic Heller-Dor operation remains an effective treatment for esophageal achalasia at a minimum 6-year follow-up","volume":"19","author":"Costantini M","year":"2005","unstructured":"Costantini M, Zaninotto G, Guirroli E, et al.. The laparoscopic Heller-Dor operation remains an effective treatment for esophageal achalasia at a minimum 6-year follow-up. Surg Endosc. 2005, 19:345-51. 10.1007\/s00464-004-8941-7","journal-title":"Surg Endosc"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2006.03784.x","article-title":"Laparoscopic cardiomyotomy for achalasia: long-term outcomes","volume":"76","author":"Bessell JR","year":"2006","unstructured":"Bessell JR, Lally CJ, Schloithe A, Jamieson GG, Devitt PG, Watson DI. Laparoscopic cardiomyotomy for achalasia: long-term outcomes. ANZ J Surg. 2006, 76:558-62. 10.1111\/j.1445-2197.2006.03784.x","journal-title":"ANZ J Surg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.4103\/0972-9941.37193","article-title":"Recurrent achalasia after Heller-Toupet procedure: laparoscopic extended redo Heller myotomy and floppy Dor","volume":"3","author":"Golash V","year":"2007","unstructured":"Golash V. Recurrent achalasia after Heller-Toupet procedure: laparoscopic extended redo Heller myotomy and floppy Dor. J Minim Access Surg. 2007, 3:104-7. 10.4103\/0972-9941.37193","journal-title":"J Minim Access Surg"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-011-2017-2","article-title":"SAGES guidelines for the surgical treatment of esophageal achalasia","volume":"26","author":"Stefanidis D","year":"2012","unstructured":"Stefanidis D, Richardson W, Farrell TM, Kohn GP, Augenstein V, Fanelli RD. SAGES guidelines for the surgical treatment of esophageal achalasia. Surg Endosc. 2012, 26:296-311. 10.1007\/s00464-011-2017-2","journal-title":"Surg Endosc"},{"key":"ref14","article-title":"Esophageal resection for end-stage achalasia","volume":"84","author":"Aiolfi A","year":"2018","unstructured":"Aiolfi A, Asti E, Bonitta G, Siboni S, Bonavina L. Esophageal resection for end-stage achalasia. Am Surg. 2018, 84:506-11.","journal-title":"Am Surg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.07.84","article-title":"Peroral endoscopic myotomy (POEM) for achalasia","volume":"11","author":"Ahmed Y","year":"2019","unstructured":"Ahmed Y, Othman MO. Peroral endoscopic myotomy (POEM) for achalasia. J Thorac Dis. 2019, 11:S1618-28. 10.21037\/jtd.2019.07.84","journal-title":"J Thorac Dis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.5056\/jnm15191","article-title":"Peroral endoscopic myotomy for treating achalasia and esophageal motility disorders","volume":"22","author":"Youn YH","year":"2016","unstructured":"Youn YH, Minami H, Chiu PW, Park H. Peroral endoscopic myotomy for treating achalasia and esophageal motility disorders. J Neurogastroenterol Motil. 2016, 22:14-24. 10.5056\/jnm15191","journal-title":"J Neurogastroenterol Motil"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.05.025","article-title":"Peroral endoscopic myotomy is a viable option for failed surgical esophagocardiomyotomy instead of redo surgical Heller myotomy: a single center prospective study","volume":"217","author":"Onimaru M","year":"2013","unstructured":"Onimaru M, Inoue H, Ikeda H, et al.. Peroral endoscopic myotomy is a viable option for failed surgical esophagocardiomyotomy instead of redo surgical Heller myotomy: a single center prospective study. J Am Coll Surg. 2013, 217:598-605. 10.1016\/j.jamcollsurg.2013.05.025","journal-title":"J Am Coll Surg"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s004649901044","article-title":"Does botulinum toxin injection make esophagomyotomy a more difficult operation?","volume":"13","author":"Horgan S","year":"1999","unstructured":"Horgan S, Hudda K, Eubanks T, McAllister J, Pellegrini CA. Does botulinum toxin injection make esophagomyotomy a more difficult operation?. Surg Endosc. 1999, 13:576-9. 10.1007\/s004649901044","journal-title":"Surg Endosc"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1023\/a:1026660921776","article-title":"Effects of previous treatment on results of laparoscopic Heller myotomy for achalasia","volume":"44","author":"Patti MG","year":"1999","unstructured":"Patti MG, Feo CV, Arcerito M, et al.. Effects of previous treatment on results of laparoscopic Heller myotomy for achalasia. Dig Dis Sci. 1999, 44:2270-2276. 10.1023\/a:1026660921776","journal-title":"Dig Dis Sci"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000217524.75529.2d","article-title":"Endoscopic therapy for achalasia before Heller myotomy results in worse outcomes than heller myotomy alone","volume":"243","author":"Smith CD","year":"2006","unstructured":"Smith CD, Stival A, Howell DL, Swafford V. Endoscopic therapy for achalasia before Heller myotomy results in worse outcomes than heller myotomy alone. Ann Surg. 2006, 243:579-84. 10.1097\/01.sla.0000217524.75529.2d","journal-title":"Ann Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/233275-end-stage-achalasia-with-megaesophagus-refractory-to-two-heller-myotomies","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T14:15:04Z","timestamp":1709820904000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/233275-end-stage-achalasia-with-megaesophagus-refractory-to-two-heller-myotomies"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,7]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.55721","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3,7]]}}}