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Chiropr Man Therap. 2021, 29:3. 10.1186\/s12998-020-00357-y","journal-title":"Chiropr Man Therap"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2016.04.016","article-title":"The physiological role of tumor necrosis factor in human immunity and its potential implications in spinal manipulative therapy: a narrative literature review","volume":"15","author":"Zhang L","year":"2016","unstructured":"Zhang L, Yao CH. The physiological role of tumor necrosis factor in human immunity and its potential implications in spinal manipulative therapy: a narrative literature review. 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J Physiol Sci. 2019, 69:589-98. 10.1007\/s12576-019-00669-6","journal-title":"J Physiol Sci"},{"key":"ref393","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.599896","article-title":"Sympathetic effect of auricular transcutaneous vagus nerve stimulation on healthy subjects: a crossover controlled clinical trial comparing vagally mediated and active control stimulation using microneurography","volume":"11","author":"Gauthey A","year":"2020","unstructured":"Gauthey A, Morra S, van de Borne P, Deriaz D, Maes N, le Polain de Waroux JB. Sympathetic effect of auricular transcutaneous vagus nerve stimulation on healthy subjects: a crossover controlled clinical trial comparing vagally mediated and active control stimulation using microneurography. Front Physiol. 2020, 11:599896. 10.3389\/fphys.2020.599896","journal-title":"Front Physiol"},{"key":"ref394","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2020.102205","article-title":"Somatosensory evoked fields predict response to vagus nerve stimulation","volume":"26","author":"Mithani K","year":"2020","unstructured":"Mithani K, Wong SM, Mikhail M, et al.. Somatosensory evoked fields predict response to vagus nerve stimulation. Neuroimage Clin. 2020, 26:102205. 10.1016\/j.nicl.2020.102205","journal-title":"Neuroimage Clin"},{"key":"ref395","doi-asserted-by":"publisher","DOI":"10.1002\/art.39043","article-title":"The somatosensory link in fibromyalgia: functional connectivity of the primary somatosensory cortex is altered by sustained pain and is associated with clinical\/autonomic dysfunction","volume":"67","author":"Kim J","year":"2015","unstructured":"Kim J, Loggia ML, Cahalan CM, et al.. 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J Electromyogr Kinesiol. 2012, 22:785-94. 10.1016\/j.jelekin.2012.01.015","journal-title":"J Electromyogr Kinesiol"},{"key":"ref398","article-title":"Proprioceptors and somatic dysfunction","volume":"74","author":"Korr IM","year":"1975","unstructured":"Korr IM. Proprioceptors and somatic dysfunction. J Am Osteopath Assoc. 1975, 74:638-50.","journal-title":"J Am Osteopath Assoc"},{"key":"ref399","article-title":"Somatic dysfunction, osteopathic manipulative treatment, and the nervous system: a few facts, some theories, many questions","volume":"86","author":"Korr IM","year":"1986","unstructured":"Korr IM. Somatic dysfunction, osteopathic manipulative treatment, and the nervous system: a few facts, some theories, many questions. J Am Osteopath Assoc. 1986, 86:109-14.","journal-title":"J Am Osteopath Assoc"},{"key":"ref400","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2006.09.014","article-title":"Cervical spine manipulation alters sensorimotor integration: a somatosensory evoked potential study","volume":"118","author":"Haavik-Taylor H","year":"2007","unstructured":"Haavik-Taylor H, Murphy B. Cervical spine manipulation alters sensorimotor integration: a somatosensory evoked potential study. Clin Neurophysiol. 2007, 118:391-402. 10.1016\/j.clinph.2006.09.014","journal-title":"Clin Neurophysiol"},{"key":"ref401","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmpt.2010.01.005","article-title":"Altered central integration of dual somatosensory input after cervical spine manipulation","volume":"33","author":"Taylor HH","year":"2010","unstructured":"Taylor HH, Murphy B. Altered central integration of dual somatosensory input after cervical spine manipulation. 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Assessing complexity in physiological systems through biomedical signals analysis. Entropy (Basel). 2020, 22:1005. 10.3390\/e22091005","journal-title":"Entropy (Basel)"},{"key":"ref408","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.48755","article-title":"Secondary analysis of a dataset to estimate the prevalence of vertebral subluxation and its implications for health promotion and prevention","volume":"15","author":"Kwon C","year":"2023","unstructured":"Kwon C, Binongo JN, McCoy M. Secondary analysis of a dataset to estimate the prevalence of vertebral subluxation and its implications for health promotion and prevention. Cureus. 2023, 15:e48755. 10.7759\/cureus.48755","journal-title":"Cureus"},{"key":"ref409","doi-asserted-by":"publisher","DOI":"10.2217\/pme.11.7","article-title":"The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?","volume":"8","author":"Lillie EO","year":"2011","unstructured":"Lillie EO, Patay B, Diamant J, Issell B, Topol EJ, Schork NJ. The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?. Per Med. 2011, 8:161-73. 10.2217\/pme.11.7","journal-title":"Per Med"},{"key":"ref410","article-title":"The assessment and correction of vertebral subluxation is central to chiropractic practice: is there a gap in the clinical evidence?","volume":"2","author":"Russell D","year":"2019","unstructured":"Russell D. The assessment and correction of vertebral subluxation is central to chiropractic practice: is there a gap in the clinical evidence?. J Contemp Chiropr. 2019, 2:4-17.","journal-title":"J Contemp Chiropr"},{"key":"ref411","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.L.00242","article-title":"Observational studies in the era of randomized trials: finding the balance","volume":"94 Suppl 1","author":"Castillo RC","year":"2012","unstructured":"Castillo RC, Scharfstein DO, MacKenzie EJ. Observational studies in the era of randomized trials: finding the balance. J Bone Joint Surg Am. 2012, 94 Suppl 1:112-17. 10.2106\/JBJS.L.00242","journal-title":"J Bone Joint Surg Am"},{"key":"ref412","article-title":"The evidence for evidence-based practice implementation","author":"Titler MG","year":"2008","unstructured":"Titler MG. The evidence for evidence-based practice implementation. Patient Safety and Quality: An Evidence-Based Handbook for Nurses. 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