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Dent Mater. 2013, 29:495-505. 10.1016\/j.dental.2013.03.011","journal-title":"Dent Mater"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.3390\/ma15165504","article-title":"Mechanical and thermal stress analysis of cervical resin composite restorations containing different ratios of zinc oxide nanoparticles: a 3D finite element study","volume":"15","author":"Yazdani N","year":"2022","unstructured":"Yazdani N, Ashrafi H, \u00d6zcan M, Nekoueimehr N, Kholdi M, Farzad A. Mechanical and thermal stress analysis of cervical resin composite restorations containing different ratios of zinc oxide nanoparticles: a 3D finite element study. Materials (Basel). 2022, 15:5504. 10.3390\/ma15165504","journal-title":"Materials (Basel)"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S246764","article-title":"The antibacterial mechanism of silver nanoparticles and its application in dentistry","volume":"15","author":"Yin IX","year":"2020","unstructured":"Yin IX, Zhang J, Zhao IS, Mei ML, Li Q, Chu CH. The antibacterial mechanism of silver nanoparticles and its application in dentistry. Int J Nanomedicine. 2020, 15:2555-62. 10.2147\/IJN.S246764","journal-title":"Int J Nanomedicine"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1590\/2177-6709.25.2.052-060.oar","article-title":"Comparison of antibacterial effects of orthodontic composites containing different nanoparticles on Streptococcus mutans at different times","volume":"25","author":"Yassaei S","year":"2020","unstructured":"Yassaei S, Nasr A, Zandi H, Motallaei MN. Comparison of antibacterial effects of orthodontic composites containing different nanoparticles on Streptococcus mutans at different times. Dental Press J Orthod. 2020, 25:52-60. 10.1590\/2177-6709.25.2.052-060.oar","journal-title":"Dental Press J Orthod"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.3390\/jfb14080402","article-title":"Influence of the loading with newly green silver nanoparticles synthesized using equisetum sylvaticum on the antibacterial activity and surface hardness of a composite resin","volume":"14","author":"T\u0103r\u0103boan\u021b\u0103 I","year":"2023","unstructured":"T\u0103r\u0103boan\u021b\u0103 I, Burlec AF, Stoleriu S, et al.. Influence of the loading with newly green silver nanoparticles synthesized using equisetum sylvaticum on the antibacterial activity and surface hardness of a composite resin. J Funct Biomater. 2023, 14:402. 10.3390\/jfb14080402","journal-title":"J Funct Biomater"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27217182","article-title":"Antibacterial activity of dental composite with ciprofloxacin loaded silver nanoparticles","volume":"27","author":"Arif W","year":"2022","unstructured":"Arif W, Rana NF, Saleem I, et al.. Antibacterial activity of dental composite with ciprofloxacin loaded silver nanoparticles. Molecules. 2022, 27:7182. 10.3390\/molecules27217182","journal-title":"Molecules"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/4743411","article-title":"A novel developed bioactive composite resin containing silver\/zinc oxide (Ag\/ZnO) nanoparticles as an antimicrobial material against Streptococcus mutans, Lactobacillus, and Candida albicans","volume":"2021","author":"Kachoei M","year":"2021","unstructured":"Kachoei M, Divband B, Rahbar M, Esmaeilzadeh M, Ghanizadeh M, Alam M. 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Sci Rep. 2020, 10:9811. 10.1038\/s41598-020-66819-8","journal-title":"Sci Rep"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejwf.2020.03.001","article-title":"Antibacterial activity and debonding force of different lingual retainers bonded with conventional composite and nanoparticle containing composite: An in\u00a0vitro study","volume":"9","author":"Kotta M","year":"2020","unstructured":"Kotta M, Gorantla S, Muddada V, Lenka RR, Karri T, Kumar S, Tivanani M. Antibacterial activity and debonding force of different lingual retainers bonded with conventional composite and nanoparticle containing composite: An in\u00a0vitro study. 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