{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:25:33Z","timestamp":1785209133132,"version":"3.55.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,26]]},"DOI":"10.7759\/cureus.59059","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T12:20:37Z","timestamp":1714134037000},"source":"Crossref","is-referenced-by-count":1,"title":["A Rare and Unusual Evolution of Hypothyroidism in Hashimoto's Thyroiditis to Graves' Disease: A Case Report and Literature Review"],"prefix":"10.7759","author":[{"given":"Amal","family":"Essouabni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima Zahrae","family":"Melki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Amine","family":"Essafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayat","family":"Aynaou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houda","family":"Salhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2008.0142","article-title":"Conversion to Graves' hyperthyroidism in a patient with hypothyroidism due to Hashimoto's thyroiditis documented by real-time thyroid ultrasonography","volume":"18","author":"Champion B","year":"2008","unstructured":"Champion B, Gopinath B, Ma G, El-Kaissi S, Wall JR. Conversion to Graves' hyperthyroidism in a patient with hypothyroidism due to Hashimoto's thyroiditis documented by real-time thyroid ultrasonography. Thyroid. 2008, 18:1135-7. 10.1089\/thy.2008.0142","journal-title":"Thyroid"},{"key":"ref2","article-title":"Hashimoto's thyroiditis following Graves' disease","volume":"42","author":"Umar H","year":"2010","unstructured":"Umar H, Muallima N, Adam JM, Sanusi H. Hashimoto's thyroiditis following Graves' disease. Acta Med Indones. 2010, 42:31-5.","journal-title":"Acta Med Indones"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.20945\/2359-3997000000086","article-title":"Conversion to Graves disease from Hashimoto thyroiditis: a study of 24 patients","volume":"62","author":"Gonzalez-Aguilera B","year":"2018","unstructured":"Gonzalez-Aguilera B, Betea D, Lutteri L, Cavalier E, Geenen V, Beckers A, Valdes-Socin H. Conversion to Graves disease from Hashimoto thyroiditis: a study of 24 patients. Arch Endocrinol Metab. 2018, 62:609-14. 10.20945\/2359-3997000000086","journal-title":"Arch Endocrinol Metab"},{"key":"ref4","article-title":"Four patients with hypothyroid Graves' disease","volume":"68","author":"Starrenburg-Razenberg AJ","year":"2010","unstructured":"Starrenburg-Razenberg AJ, Castro Cabezas M, Gan IM, Njo TL, Rietveld AP, Elte JW. Four patients with hypothyroid Graves' disease. Neth J Med. 2010, 68:178-80.","journal-title":"Neth J Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-64-4-718","article-title":"The mechanism of spontaneous hypothyroidism in patients with Graves' disease after antithyroid drug treatment","volume":"64","author":"Tamai H","year":"1987","unstructured":"Tamai H, Hirota Y, Kasagi K, et al.. The mechanism of spontaneous hypothyroidism in patients with Graves' disease after antithyroid drug treatment. J Clin Endocrinol Metab. 1987, 64:718-22. 10.1210\/jcem-64-4-718","journal-title":"J Clin Endocrinol Metab"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-14-0047","article-title":"Mechanisms in endocrinology: autoimmune thyroid disease: old and new players","volume":"170","author":"Effraimidis G","year":"2014","unstructured":"Effraimidis G, Wiersinga WM. Mechanisms in endocrinology: autoimmune thyroid disease: old and new players. Eur J Endocrinol. 2014, 170:R241-52. 10.1530\/EJE-14-0047","journal-title":"Eur J Endocrinol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2020.101387","article-title":"Graves' disease: epidemiology, genetic and environmental risk factors and viruses","volume":"34","author":"Antonelli A","year":"2020","unstructured":"Antonelli A, Ferrari SM, Ragusa F, et al.. Graves' disease: epidemiology, genetic and environmental risk factors and viruses. Best Pract Res Clin Endocrinol Metab. 2020, 34:101387. 10.1016\/j.beem.2020.101387","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/antib12030048","article-title":"The usefulness of thyroid antibodies in the diagnostic approach to autoimmune thyroid disease","volume":"12","author":"Vargas-Uricoechea H","year":"2023","unstructured":"Vargas-Uricoechea H, Nogueira JP, Pinz\u00f3n-Fern\u00e1ndez MV, Schwarzstein D. The usefulness of thyroid antibodies in the diagnostic approach to autoimmune thyroid disease. Antibodies (Basel). 2023, 12:48. 10.3390\/antib12030048","journal-title":"Antibodies (Basel)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59040757","article-title":"Autoimmune thyroiditis shifting from Hashimoto's thyroiditis to Graves' disease","volume":"59","author":"Daramjav N","year":"2023","unstructured":"Daramjav N, Takagi J, Iwayama H, et al.. Autoimmune thyroiditis shifting from Hashimoto's thyroiditis to Graves' disease. Medicina (Kaunas). 2023, 59:757. 10.3390\/medicina59040757","journal-title":"Medicina (Kaunas)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0374","article-title":"Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa","volume":"23","author":"McLachlan SM","year":"2013","unstructured":"McLachlan SM, Rapoport B. Thyrotropin-blocking autoantibodies and thyroid-stimulating autoantibodies: potential mechanisms involved in the pendulum swinging from hypothyroidism to hyperthyroidism or vice versa. Thyroid. 2013, 23:14-24. 10.1089\/thy.2012.0374","journal-title":"Thyroid"},{"key":"ref11","article-title":"Basedow disease following autoimmune primary hypothyroidism. Apropos of 7 cases. (Article in French)","volume":"55","author":"Osorio-Salazar C","year":"1994","unstructured":"Osorio-Salazar C, Lecomte P, Madec AM, Baulieu JL. Basedow disease following autoimmune primary hypothyroidism. Apropos of 7 cases. (Article in French). Ann Endocrinol (Paris). 1994, 55:185-9.","journal-title":"Ann Endocrinol (Paris)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2012.04397.x","article-title":"Thyrotrophin receptor antibody characteristics in a woman with long-standing Hashimoto's who developed Graves' disease and pretibial myxoedema","volume":"77","author":"Kamath C","year":"2012","unstructured":"Kamath C, Young S, Kabelis K, et al.. Thyrotrophin receptor antibody characteristics in a woman with long-standing Hashimoto's who developed Graves' disease and pretibial myxoedema. Clin Endocrinol (Oxf). 2012, 77:465-70. 10.1111\/j.1365-2265.2012.04397.x","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-28-11-1623","article-title":"Ophthalmopathy without hyperthyroidism in patients with histologic Hashimoto's thyroiditis","volume":"28","author":"Wyse EP","year":"1968","unstructured":"Wyse EP, McConahey WM, Woolner LB, Scholz DA, Kearns TP. Ophthalmopathy without hyperthyroidism in patients with histologic Hashimoto's thyroiditis. J Clin Endocrinol Metab. 1968, 28:1623-9. 10.1210\/jcem-28-11-1623","journal-title":"J Clin Endocrinol Metab"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-14942","article-title":"TSBAb (TSH-stimulation blocking antibody) and TSAb (thyroid stimulating antibody) in TSBAb-positive patients with hypothyroidism and Graves' patients with hyperthyroidism","volume":"33","author":"Takasu N","year":"2001","unstructured":"Takasu N, Yamashiro K, Ochi Y, Sato Y, Nagata A, Komiya I, Yoshimura H. TSBAb (TSH-stimulation blocking antibody) and TSAb (thyroid stimulating antibody) in TSBAb-positive patients with hypothyroidism and Graves' patients with hyperthyroidism. Horm Metab Res. 2001, 33:232-7. 10.1055\/s-2001-14942","journal-title":"Horm Metab Res"},{"key":"ref15","article-title":"Hyperthyroidism following hypothyroidism--a case report","volume":"46","author":"Kang BH","year":"1991","unstructured":"Kang BH. Hyperthyroidism following hypothyroidism--a case report. Med J Malaysia. 1991, 46:287-9.","journal-title":"Med J Malaysia"},{"key":"ref16","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/182176","article-title":"Changes of TSH-stimulation blocking antibody (TSBAb) and thyroid stimulating antibody (TSAb) over 10 years in 34 TSBAb-positive patients with hypothyroidism and in 98 TSAb-positive Graves\u2019 patients with hyperthyroidism: reevaluation of TSBAb and TSAb in TSH-receptor-antibody (TRAb)-positive patients","volume":"2012","author":"Takasu N","year":"2012","unstructured":"Takasu N, Matsushita M. Changes of TSH-stimulation blocking antibody (TSBAb) and thyroid stimulating antibody (TSAb) over 10 years in 34 TSBAb-positive patients with hypothyroidism and in 98 TSAb-positive Graves\u2019 patients with hyperthyroidism: reevaluation of TSBAb and TSAb in TSH-receptor-antibody (TRAb)-positive patients. J Thyroid Res. 2012, 2012:182176.","journal-title":"J Thyroid Res"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1992.tb00960.x","article-title":"Changes in stimulating and blocking TSH receptor antibodies in a patient undergoing three cycles of transition from hypo to hyper-thyroidism and back to hypothyroidism","volume":"36","author":"Kraiem Z","year":"1992","unstructured":"Kraiem Z, Baron E, Kahana L, Sadeh O, Sheinfeld M. Changes in stimulating and blocking TSH receptor antibodies in a patient undergoing three cycles of transition from hypo to hyper-thyroidism and back to hypothyroidism. Clin Endocrinol (Oxf). 1992, 36:211-4. 10.1111\/j.1365-2265.1992.tb00960.x","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1507\/endocrj.50.113","article-title":"TSH-receptor antibody measurement in patients with various thyrotoxicosis and Hashimoto's thyroiditis: a comparison of two two-step assays, coated plate ELISA using porcine TSH-receptor and coated tube radioassay using human recombinant TSH-receptor","volume":"50","author":"Kamijo K","year":"2003","unstructured":"Kamijo K. TSH-receptor antibody measurement in patients with various thyrotoxicosis and Hashimoto's thyroiditis: a comparison of two two-step assays, coated plate ELISA using porcine TSH-receptor and coated tube radioassay using human recombinant TSH-receptor. Endocr J. 2003, 50:113-6. 10.1507\/endocrj.50.113","journal-title":"Endocr J"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-020-00602-8","article-title":"Basedow's disease with associated features of Hashimoto's thyroiditis based on histopathological findings","volume":"20","author":"Horiya M","year":"2020","unstructured":"Horiya M, Anno T, Kawasaki F, et al.. Basedow's disease with associated features of Hashimoto's thyroiditis based on histopathological findings. BMC Endocr Disord. 2020, 20:120. 10.1186\/s12902-020-00602-8","journal-title":"BMC Endocr Disord"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3402\/jchimp.v4.25734","article-title":"Oscillating hypothyroidism and hyperthyroidism - a case-based review","volume":"4","author":"Fan W","year":"2014","unstructured":"Fan W, Tandon P, Krishnamurthy M. Oscillating hypothyroidism and hyperthyroidism - a case-based review. J Community Hosp Intern Med Perspect. 2014, 4:25734. 10.3402\/jchimp.v4.25734","journal-title":"J Community Hosp Intern Med Perspect"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2010.03831.x","article-title":"Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sample","volume":"73","author":"Evans M","year":"2010","unstructured":"Evans M, Sanders J, Tagami T, et al.. Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sample. Clin Endocrinol (Oxf). 2010, 73:404-12. 10.1111\/j.1365-2265.2010.03831.x","journal-title":"Clin Endocrinol (Oxf)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/237947-a-rare-and-unusual-evolution-of-hypothyroidism-in-hashimotos-thyroiditis-to-graves-disease-a-case-report-and-literature-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T12:20:43Z","timestamp":1714134043000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/237947-a-rare-and-unusual-evolution-of-hypothyroidism-in-hashimotos-thyroiditis-to-graves-disease-a-case-report-and-literature-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,26]]},"references-count":21,"URL":"https:\/\/doi.org\/10.7759\/cureus.59059","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4,26]]}}}