{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T15:32:05Z","timestamp":1788449525740,"version":"build-2803163510"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,1]]},"DOI":"10.7759\/cureus.59476","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T19:40:51Z","timestamp":1714592451000},"source":"Crossref","is-referenced-by-count":1,"title":["Multimodal Neurologic Monitoring in Patients Undergoing Extracorporeal Membrane Oxygenation"],"prefix":"10.7759","author":[{"given":"Khwaja","family":"Siddiqui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad U","family":"Hafeez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed O","family":"Kazmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subhasis","family":"Chatterjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Bershad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Hirzallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chethan","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Damani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2008.08.009","article-title":"Review of ECMO (extra corporeal membrane oxygenation) support in critically ill adult patients","volume":"17 Suppl 4","author":"Marasco SF","year":"2008","unstructured":"Marasco SF, Lukas G, McDonald M, McMillan J, Ihle B. Review of ECMO (extra corporeal membrane oxygenation) support in critically ill adult patients. Heart Lung Circ. 2008, 17 Suppl 4:S41-7. 10.1016\/j.hlc.2008.08.009","journal-title":"Heart Lung Circ"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2072-1439.2015.07.17","article-title":"Extra corporeal membrane oxygenation (ECMO) review of a lifesaving technology","volume":"7","author":"Makdisi G","year":"2015","unstructured":"Makdisi G, Wang IW. Extra corporeal membrane oxygenation (ECMO) review of a lifesaving technology. J Thorac Dis. 2015, 7:E166-76. 10.3978\/j.issn.2072-1439.2015.07.17","journal-title":"J Thorac Dis"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001865","article-title":"In-hospital neurologic complications in adult patients undergoing venoarterial extracorporeal membrane oxygenation: results from the Extracorporeal Life Support Organization Registry","volume":"44","author":"Lorusso R","year":"2016","unstructured":"Lorusso R, Barili F, Mauro MD, et al.. In-hospital neurologic complications in adult patients undergoing venoarterial extracorporeal membrane oxygenation: results from the Extracorporeal Life Support Organization Registry. Crit Care Med. 2016, 44:e964-72. 10.1097\/CCM.0000000000001865","journal-title":"Crit Care Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03533-5","article-title":"Neurological complications during veno-venous extracorporeal membrane oxygenation: does the configuration matter? A retrospective analysis of the ELSO database","volume":"25","author":"Lorusso R","year":"2021","unstructured":"Lorusso R, Belliato M, Mazzeffi M, et al.. Neurological complications during veno-venous extracorporeal membrane oxygenation: does the configuration matter? A retrospective analysis of the ELSO database. Crit Care. 2021, 25:107. 10.1186\/s13054-021-03533-5","journal-title":"Crit Care"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2017.03.001","article-title":"Neurologic complications of extracorporeal membrane oxygenation: a review","volume":"31","author":"Xie A","year":"2017","unstructured":"Xie A, Lo P, Yan TD, Forrest P. Neurologic complications of extracorporeal membrane oxygenation: a review. J Cardiothorac Vasc Anesth. 2017, 31:1836-46. 10.1053\/j.jvca.2017.03.001","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.11586","article-title":"Determination of brain death\/death by neurologic criteria: the World Brain Death Project","volume":"324","author":"Greer DM","year":"2020","unstructured":"Greer DM, Shemie SD, Lewis A, et al..  Determination of brain death\/death by neurologic criteria: the World Brain Death Project. JAMA. 2020, 324:1078-97. 10.1001\/jama.2020.11586","journal-title":"JAMA"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.14060","article-title":"Transcranial Doppler is an effective method in assessing cerebral blood flow patterns during peripheral venoarterial extracorporeal membrane oxygenation","volume":"34","author":"Salna M","year":"2019","unstructured":"Salna M, Ikegami H, Willey JZ, et al.. Transcranial Doppler is an effective method in assessing cerebral blood flow patterns during peripheral venoarterial extracorporeal membrane oxygenation. J Card Surg. 2019, 34:447-52. 10.1111\/jocs.14060","journal-title":"J Card Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000001013","article-title":"Noninvasive neurological monitoring in extracorporeal membrane oxygenation","volume":"66","author":"Cho SM","year":"2020","unstructured":"Cho SM, Ziai W, Mayasi Y, et al.. Noninvasive neurological monitoring in extracorporeal membrane oxygenation. ASAIO J. 2020, 66:388-93. 10.1097\/MAT.0000000000001013","journal-title":"ASAIO J"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2019.08.44","article-title":"Evaluation of a heparin monitoring protocol for extracorporeal membrane oxygenation and review of the literature","volume":"11","author":"Colman E","year":"2019","unstructured":"Colman E, Yin EB, Laine G, et al.. Evaluation of a heparin monitoring protocol for extracorporeal membrane oxygenation and review of the literature. J Thorac Dis. 2019, 11:3325-35. 10.21037\/jtd.2019.08.44","journal-title":"J Thorac Dis"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000000415","article-title":"Neuromonitoring during extracorporeal membrane oxygenation: a systematic review of the literature","volume":"16","author":"Bembea MM","year":"2015","unstructured":"Bembea MM, Felling R, Anton B, Salorio CF, Johnston MV. Neuromonitoring during extracorporeal membrane oxygenation: a systematic review of the literature. Pediatr Crit Care Med. 2015, 16:558-64. 10.1097\/PCC.0000000000000415","journal-title":"Pediatr Crit Care Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/1550059419892757","article-title":"Neurophysiological findings and brain injury pattern in patients on ECMO","volume":"52","author":"Cho SM","year":"2021","unstructured":"Cho SM, Choi CW, Whitman G, Suarez JI, Martinez NC, Geocadin RG, Ritzl EK. Neurophysiological findings and brain injury pattern in patients on ECMO. Clin EEG Neurosci. 2021, 52:462-9. 10.1177\/1550059419892757","journal-title":"Clin EEG Neurosci"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.922355","article-title":"A standardized multimodal neurological monitoring protocol-guided cerebral protection therapy for venoarterial extracorporeal membrane oxygenation supported patients","volume":"9","author":"Shi X","year":"2022","unstructured":"Shi X, Gu Q, Li Y, Diao M, Wen X, Hu W, Xi S. A standardized multimodal neurological monitoring protocol-guided cerebral protection therapy for venoarterial extracorporeal membrane oxygenation supported patients. Front Med (Lausanne). 2022, 9:922355. 10.3389\/fmed.2022.922355","journal-title":"Front Med (Lausanne)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2021.09.063","article-title":"Neuromonitoring detects brain injury in patients receiving extracorporeal membrane oxygenation support","volume":"165","author":"Ong CS","year":"2023","unstructured":"Ong CS, Etchill E, Dong J, et al.. Neuromonitoring detects brain injury in patients receiving extracorporeal membrane oxygenation support. J Thorac Cardiovasc Surg. 2023, 165:2104-10.e1. 10.1016\/j.jtcvs.2021.09.063","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.713333","article-title":"Narrative review of neurologic complications in adults on ECMO: Prevalence, risks, outcomes, and prevention strategies","volume":"8","author":"Zhang H","year":"2021","unstructured":"Zhang H, Xu J, Yang X, Zou X, Shu H, Liu Z, Shang Y. Narrative review of neurologic complications in adults on ECMO: Prevalence, risks, outcomes, and prevention strategies. Front Med (Lausanne). 2021, 8:713333. 10.3389\/fmed.2021.713333","journal-title":"Front Med (Lausanne)"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002502","article-title":"Neurologic injury in adults supported with veno-venous extracorporeal membrane oxygenation for respiratory failure: findings from the Extracorporeal Life Support Organization database","volume":"45","author":"Lorusso R","year":"2017","unstructured":"Lorusso R, Gelsomino S, Parise O, et al.. Neurologic injury in adults supported with veno-venous extracorporeal membrane oxygenation for respiratory failure: findings from the Extracorporeal Life Support Organization database. Crit Care Med. 2017, 45:1389-97. 10.1097\/CCM.0000000000002502","journal-title":"Crit Care Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200002000-00039","article-title":"Venovenous versus venoarterial extracorporeal life support for pediatric respiratory failure: are there differences in survival and acute complications?","volume":"28","author":"Zahraa JN","year":"2000","unstructured":"Zahraa JN, Moler FW, Annich GM, Maxvold NJ, Bartlett RH, Custer JR. Venovenous versus venoarterial extracorporeal life support for pediatric respiratory failure: are there differences in survival and acute complications?. Crit Care Med. 2000, 28:521-5. 10.1097\/00003246-200002000-00039","journal-title":"Crit Care Med"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-013-2985-x","article-title":"Neurologic complications in neonates supported with extracorporeal membrane oxygenation. An analysis of ELSO registry data","volume":"39","author":"Polito A","year":"2013","unstructured":"Polito A, Barrett CS, Wypij D, Rycus PT, Netto R, Cogo PE, Thiagarajan RR. Neurologic complications in neonates supported with extracorporeal membrane oxygenation. An analysis of ELSO registry data. Intensive Care Med. 2013, 39:1594-601. 10.1007\/s00134-013-2985-x","journal-title":"Intensive Care Med"},{"key":"ref18","article-title":"Neurologic complications and neuromonitoring on ECMO","author":"Pinto VL","year":"2019","unstructured":"Pinto VL. Neurologic complications and neuromonitoring on ECMO. Advances in Extracorporeal Membrane Oxygenation - Volume 3. Firstenberg MS (ed): IntechOpen, London, UK; 2019."},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003223","article-title":"Acute neurologic complications during extracorporeal membrane oxygenation: a systematic review","volume":"46","author":"Sutter R","year":"2018","unstructured":"Sutter R, Tisljar K, Marsch S. Acute neurologic complications during extracorporeal membrane oxygenation: a systematic review. Crit Care Med. 2018, 46:1506-13. 10.1097\/CCM.0000000000003223","journal-title":"Crit Care Med"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0376-2491.2019.24.014","article-title":"China statistics of extracorporeal life support in 2018 [Article in Chinese]","volume":"99","author":"Li CL","year":"2019","unstructured":"Li CL, Hou XT, Hei FL, et al.. China statistics of extracorporeal life support in 2018 [Article in Chinese]. Zhonghua Yi Xue Za Zhi. 2019, 99:1911-5. 10.3760\/cma.j.issn.0376-2491.2019.24.014","journal-title":"Zhonghua Yi Xue Za Zhi"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2016.07.050","article-title":"Transcranial Doppler changes in patients treated with extracorporeal membrane oxygenation","volume":"25","author":"Kavi T","year":"2016","unstructured":"Kavi T, Esch M, Rinsky B, Rosengart A, Lahiri S, Lyden PD. Transcranial Doppler changes in patients treated with extracorporeal membrane oxygenation. J Stroke Cerebrovasc Dis. 2016, 25:2882-5. 10.1016\/j.jstrokecerebrovasdis.2016.07.050","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000636","article-title":"Retrospective analysis of transcranial doppler patterns in veno-arterial extracorporeal membrane oxygenation patients: feasibility of cerebral circulatory arrest diagnosis","volume":"64","author":"Marinoni M","year":"2018","unstructured":"Marinoni M, Cianchi G, Trapani S, et al.. Retrospective analysis of transcranial doppler patterns in veno-arterial extracorporeal membrane oxygenation patients: feasibility of cerebral circulatory arrest diagnosis. ASAIO J. 2018, 64:175-82. 10.1097\/MAT.0000000000000636","journal-title":"ASAIO J"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000721","article-title":"TCD and cerebral circulatory arrest in VA ECMO patients","volume":"64","author":"Marinoni M","year":"2018","unstructured":"Marinoni M, Cianchi G, Trapani S, et al.. TCD and cerebral circulatory arrest in VA ECMO patients. ASAIO J. 2018, 64:e79. 10.1097\/MAT.0000000000000721","journal-title":"ASAIO J"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3182712d62","article-title":"Extracorporeal membrane oxygenation and cerebral blood flow velocity in children","volume":"14","author":"O'Brien NF","year":"2013","unstructured":"O'Brien NF, Hall MW. Extracorporeal membrane oxygenation and cerebral blood flow velocity in children. Pediatr Crit Care Med. 2013, 14:e126-34. 10.1097\/PCC.0b013e3182712d62","journal-title":"Pediatr Crit Care Med"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001778","article-title":"Cerebrovascular physiology during pediatric extracorporeal membrane oxygenation: a multicenter study using transcranial Doppler ultrasonography","volume":"20","author":"O'Brien NF","year":"2019","unstructured":"O'Brien NF, Buttram SD, Maa T, Lovett ME, Reuter-Rice K, LaRovere KL. Cerebrovascular physiology during pediatric extracorporeal membrane oxygenation: a multicenter study using transcranial Doppler ultrasonography. Pediatr Crit Care Med. 2019, 20:178-86. 10.1097\/PCC.0000000000001778","journal-title":"Pediatr Crit Care Med"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/3237810","article-title":"Cerebral pathophysiology in extracorporeal membrane oxygenation: pitfalls in daily clinical management","volume":"2018","author":"Kazmi SO","year":"2018","unstructured":"Kazmi SO, Sivakumar S, Karakitsos D, Alharthy A, Lazaridis C. Cerebral pathophysiology in extracorporeal membrane oxygenation: pitfalls in daily clinical management. Crit Care Res Pract. 2018, 2018:3237810. 10.1155\/2018\/3237810","journal-title":"Crit Care Res Pract"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1117\/1.NPh.4.4.041410","article-title":"Impairment of cerebral autoregulation in pediatric extracorporeal membrane oxygenation associated with neuroimaging abnormalities","volume":"4","author":"Tian F","year":"2017","unstructured":"Tian F, Morriss MC, Chalak L, Venkataraman R, Ahn C, Liu H, Raman L. Impairment of cerebral autoregulation in pediatric extracorporeal membrane oxygenation associated with neuroimaging abnormalities. Neurophotonics. 2017, 4:041410. 10.1117\/1.NPh.4.4.041410","journal-title":"Neurophotonics"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25539","article-title":"Early electroencephalogram for neurologic prognostication: a self-fulfilling prophecy?","volume":"86","author":"Cho SM","year":"2019","unstructured":"Cho SM, Mulder M, Geocadin RG. Early electroencephalogram for neurologic prognostication: a self-fulfilling prophecy?. Ann Neurol. 2019, 86:473-4. 10.1002\/ana.25539","journal-title":"Ann Neurol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-020-01099-8","article-title":"Neurological prognostication using electroencephalogram in adult veno-arterial extracorporeal membrane oxygenation: limitations and recommendations","volume":"33","author":"Cho SM","year":"2020","unstructured":"Cho SM, Ritzl EK. Neurological prognostication using electroencephalogram in adult veno-arterial extracorporeal membrane oxygenation: limitations and recommendations. Neurocrit Care. 2020, 33:652-4. 10.1007\/s12028-020-01099-8","journal-title":"Neurocrit Care"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000239","article-title":"Neuron-specific enolase levels in adults under venoarterial extracorporeal membrane oxygenation","volume":"2","author":"Reuter J","year":"2020","unstructured":"Reuter J, Peoc'h K, Bouadma L, et al.. Neuron-specific enolase levels in adults under venoarterial extracorporeal membrane oxygenation. Crit Care Explor. 2020, 2:e0239. 10.1097\/CCE.0000000000000239","journal-title":"Crit Care Explor"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/241078-multimodal-neurologic-monitoring-in-patients-undergoing-extracorporeal-membrane-oxygenation","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T19:43:03Z","timestamp":1714592583000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/241078-multimodal-neurologic-monitoring-in-patients-undergoing-extracorporeal-membrane-oxygenation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,1]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.59476","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5,1]]}}}