{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T12:41:15Z","timestamp":1781008875958,"version":"3.54.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,10]]},"DOI":"10.7759\/cureus.60059","type":"journal-article","created":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T01:54:58Z","timestamp":1715392498000},"source":"Crossref","is-referenced-by-count":1,"title":["Low Anterior Resection Syndrome and Quality of Life of Patients After Sphincter Preservation Surgery: A Prospective Study"],"prefix":"10.7759","author":[{"given":"Chandramohan","family":"K","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhil T","family":"Jacob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhu","family":"Muralee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mira W","family":"Sudham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayadevi","family":"L","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sithara","family":"Balakrishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9223","article-title":"Impact of bowel dysfunction on quality of life after sphincter-preserving resection for rectal cancer","volume":"100","author":"Emmertsen KJ","year":"2013","unstructured":"Emmertsen KJ, Laurberg S. Impact of bowel dysfunction on quality of life after sphincter-preserving resection for rectal cancer. Br J Surg. 2013, 100:1377-87. 10.1002\/bjs.9223","journal-title":"Br J Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70236-X","article-title":"Anterior resection syndrome","volume":"1016","author":"Bryant CL","year":"2012","unstructured":"Bryant CL, Lunniss PJ, Knowles CH, Thaha MA, Chan CL.. Anterior resection syndrome. Lancet Oncol. 2012, 1016:1470-2045. 10.1016\/S1470-2045(12)70236-X","journal-title":"Lancet Oncol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000116","article-title":"Low anterior resection syndrome and quality of life: an international multicenter study","volume":"57","author":"Juul T","year":"2014","unstructured":"Juul T, Ahlberg M, Biondo S, et al.. Low anterior resection syndrome and quality of life: an international multicenter study. Dis Colon Rectum. 2014, 57:585-91. 10.1097\/DCR.0000000000000116","journal-title":"Dis Colon Rectum"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31824f1c21","article-title":"Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer","volume":"255","author":"Emmertsen KJ","year":"2012","unstructured":"Emmertsen KJ, Laurberg S. Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer. Ann Surg. 2012, 255:922-8. 10.1097\/SLA.0b013e31824f1c21","journal-title":"Ann Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/BF02050307","article-title":"Etiology and management of fecal incontinence","volume":"36","author":"Jorge JM","year":"1993","unstructured":"Jorge JM, Wexner SD. Etiology and management of fecal incontinence. Dis Colon Rectum. 1993, 36:77-97. 10.1007\/BF02050307","journal-title":"Dis Colon Rectum"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e318245190e","article-title":"Internal anal sphincter parasympathetic-nitrergic and sympathetic-adrenergic innervation: a 3-dimensional morphological and functional analysis","volume":"55","author":"Moszkowicz D","year":"2012","unstructured":"Moszkowicz D, Peschaud F, Bessede T, Benoit G, Alsaid B. Internal anal sphincter parasympathetic-nitrergic and sympathetic-adrenergic innervation: a 3-dimensional morphological and functional analysis. Dis Colon Rectum. 2012, 55:473-81. 10.1097\/DCR.0b013e318245190e","journal-title":"Dis Colon Rectum"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.02942.x","article-title":"Preoperative MRI sphincter morphology and anal manometry: can they be markers of functional outcome following anterior resection for rectal cancer?","volume":"14","author":"How P","year":"2012","unstructured":"How P, Evans J, Moran B, Swift I, Brown G. Preoperative MRI sphincter morphology and anal manometry: can they be markers of functional outcome following anterior resection for rectal cancer?. Colorectal Dis. 2012, 14:e339-45. 10.1111\/j.1463-1318.2012.02942.x","journal-title":"Colorectal Dis"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-012-0909-3","article-title":"Low anterior resection syndrome (LARS): cause and effect and reconstructive considerations","volume":"17","author":"Ziv Y","year":"2013","unstructured":"Ziv Y, Zbar A, Bar-Shavit Y, Igov I. Low anterior resection syndrome (LARS): cause and effect and reconstructive considerations. Tech Coloproctol. 2013, 17:151-62. 10.1007\/s10151-012-0909-3","journal-title":"Tech Coloproctol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2013.07.004","article-title":"Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer","volume":"108","author":"Bregendahl S","year":"2013","unstructured":"Bregendahl S, Emmertsen KJ, Fassov J, Krogh K, Zhao J, Gregersen H, Laurberg S. Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer. Radiother Oncol. 2013, 108:331-6. 10.1016\/j.radonc.2013.07.004","journal-title":"Radiother Oncol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2008.2","article-title":"Neorectal irritability after short-term preoperative radiotherapy and surgical resection for rectal cancer","volume":"104","author":"Bakx R","year":"2009","unstructured":"Bakx R, Doeksen A, Slors JF, Bemelman WA, van Lanschot JJ, Boeckxstaens GE. Neorectal irritability after short-term preoperative radiotherapy and surgical resection for rectal cancer. Am J Gastroenterol. 2009, 104:133-41. 10.1038\/ajg.2008.2","journal-title":"Am J Gastroenterol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-001-0144-y","article-title":"Barostat examination of proximal site of the anastomosis in patients with rectal cancer after low anterior resection","volume":"25","author":"Mochiki E","year":"2001","unstructured":"Mochiki E, Nakabayashi T, Suzuki H, Haga N, Fujita K, Asao T, Kuwano H. Barostat examination of proximal site of the anastomosis in patients with rectal cancer after low anterior resection. World J Surg. 2001, 25:1377-82. 10.1007\/s00268-001-0144-y","journal-title":"World J Surg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2014.06.020","article-title":"Health-related quality of life 14 years after preoperative short-term radiotherapy and total mesorectal excision for rectal cancer: report of a multicenter randomised trial","volume":"50","author":"Wiltink LM","year":"2014","unstructured":"Wiltink LM, Chen TY, Nout RA, et al.. Health-related quality of life 14 years after preoperative short-term radiotherapy and total mesorectal excision for rectal cancer: report of a multicenter randomised trial. Eur J Cancer. 2014, 50:2390-8. 10.1016\/j.ejca.2014.06.020","journal-title":"Eur J Cancer"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clcc.2014.12.007","article-title":"Bowel function 14 years after preoperative short-course radiotherapy and total mesorectal excision for rectal cancer: report of a multicenter randomized trial","volume":"14","author":"Chen TY","year":"2015","unstructured":"Chen TY, Wiltink LM, Nout RA, Meershoek-Klein Kranenbarg E, Laurberg S, Marijnen CA, van de Velde CJ. Bowel function 14 years after preoperative short-course radiotherapy and total mesorectal excision for rectal cancer: report of a multicenter randomized trial. Clin Colorectal Cancer. 2015, 14:106-14. 10.1016\/j.clcc.2014.12.007","journal-title":"Clin Colorectal Cancer"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12244","article-title":"Bowel dysfunction after low anterior resection with and without neoadjuvant therapy for rectal cancer: a population-based cross-sectional study","volume":"15","author":"Bregendahl S","year":"2013","unstructured":"Bregendahl S, Emmertsen KJ, Lous J, Laurberg S. Bowel dysfunction after low anterior resection with and without neoadjuvant therapy for rectal cancer: a population-based cross-sectional study. Colorectal Dis. 2013, 15:1130-9. 10.1111\/codi.12244","journal-title":"Colorectal Dis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-016-2659-6","article-title":"Long-term functional follow-up after anterior rectal resection for cancer","volume":"32","author":"Sturiale A","year":"2017","unstructured":"Sturiale A, Martellucci J, Zurli L, et al.. Long-term functional follow-up after anterior rectal resection for cancer. Int J Colorectal Dis. 2017, 32:83-8. 10.1007\/s00384-016-2659-6","journal-title":"Int J Colorectal Dis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2004.12.009","article-title":"Quality of life in colorectal cancer patients with colectomy and the validation of the Functional Assessment of Cancer Therapy-Colorectal (FACT-C), Version 4","volume":"30","author":"Yoo HJ","year":"2005","unstructured":"Yoo HJ, Kim JC, Eremenco S, Han OS. Quality of life in colorectal cancer patients with colectomy and the validation of the Functional Assessment of Cancer Therapy-Colorectal (FACT-C), Version 4. J Pain Symptom Manage. 2005, 30:24-32. 10.1016\/j.jpainsymman.2004.12.009","journal-title":"J Pain Symptom Manage"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/250796-low-anterior-resection-syndrome-and-quality-of-life-of-patients-after-sphincter-preservation-surgery-a-prospective-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,11]],"date-time":"2024-05-11T01:55:05Z","timestamp":1715392505000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/250796-low-anterior-resection-syndrome-and-quality-of-life-of-patients-after-sphincter-preservation-surgery-a-prospective-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,10]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.60059","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5,10]]}}}