{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:59:50Z","timestamp":1792094390335,"version":"4.4.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,27]]},"DOI":"10.7759\/cureus.61201","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T05:15:16Z","timestamp":1716873316000},"source":"Crossref","is-referenced-by-count":1,"title":["Unmasking the Rarity: A Case Report on Type B Lactic Acidosis in Pediatric Acute Lymphoblastic Leukemia"],"prefix":"10.7759","author":[{"given":"Keta","family":"Vagha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atish","family":"Bakane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aashita","family":"Malik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaitanya Kumar","family":"Javvaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunita","family":"Vagha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddhartha","family":"Murhekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1400972","article-title":"Acute lymphoblastic leukemia in children","volume":"373","author":"Hunger SP","year":"2015","unstructured":"Hunger SP, Mullighan CG. Acute lymphoblastic leukemia in children. N Engl J Med. 2015, 373:1541-52. 10.1056\/NEJMra1400972","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0b013e318125759a","article-title":"Type B lactic acidosis as a severe metabolic complication in lymphoma and leukemia: a case series from a single institution and literature review","volume":"86","author":"Friedenberg AS","year":"2007","unstructured":"Friedenberg AS, Brandoff DE, Schiffman FJ. Type B lactic acidosis as a severe metabolic complication in lymphoma and leukemia: a case series from a single institution and literature review. Medicine (Baltimore). 2007, 86:225-32.","journal-title":"Medicine (Baltimore)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2011.125","article-title":"Type B lactic acidosis secondary to malignancy: case report, review of published cases, insights into pathogenesis, and prospects for therapy","volume":"11","author":"Ruiz JP","year":"2011","unstructured":"Ruiz JP, Singh AK, Hart P. Type B lactic acidosis secondary to malignancy: case report, review of published cases, insights into pathogenesis, and prospects for therapy. ScientificWorldJournal. 2011, 11:1316-24. 10.1100\/tsw.2011.125","journal-title":"ScientificWorldJournal"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3390\/ph15121496","article-title":"Lactic acidosis related to pharmacotherapy and human diseases","volume":"15","author":"Zanza C","year":"2022","unstructured":"Zanza C, Facelli V, Romenskaya T, et al.. Lactic acidosis related to pharmacotherapy and human diseases. Pharmaceuticals (Basel). 2022, 15:1496. 10.3390\/ph15121496","journal-title":"Pharmaceuticals (Basel)"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s13049-017-0415-8","article-title":"Serum lactate is an independent predictor of hospital mortality in critically ill patients in the emergency department: a retrospective study","volume":"25","author":"Bou Chebl R","year":"2017","unstructured":"Bou Chebl R, El Khuri C, Shami A, Rajha E, Faris N, Bachir R, Abou Dagher G. Serum lactate is an independent predictor of hospital mortality in critically ill patients in the emergency department: a retrospective study. Scand J Trauma Resusc Emerg Med. 2017, 25:69. 10.1186\/s13049-017-0415-8","journal-title":"Scand J Trauma Resusc Emerg Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1309483","article-title":"Lactic acidosis","volume":"371","author":"Kraut JA","year":"2014","unstructured":"Kraut JA, Madias NE. Lactic acidosis. N Engl J Med. 2014, 371:2309-19. 10.1056\/NEJMra1309483","journal-title":"N Engl J Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.2561","article-title":"Persistent lactic acidosis: thinking outside the box","volume":"10","author":"Arif H","year":"2018","unstructured":"Arif H, Zahid S, Kaura A. Persistent lactic acidosis: thinking outside the box. Cureus. 2018, 10:e2561. 10.7759\/cureus.2561","journal-title":"Cureus"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2013.06.012","article-title":"Etiology and therapeutic approach to elevated lactate levels","volume":"88","author":"Andersen LW","year":"2013","unstructured":"Andersen LW, Mackenhauer J, Roberts JC, Berg KM, Cocchi MN, Donnino MW. Etiology and therapeutic approach to elevated lactate levels. Mayo Clin Proc. 2013, 88:1127-40. 10.1016\/j.mayocp.2013.06.012","journal-title":"Mayo Clin Proc"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20011101)92:9<2237::aid-cncr1569>3.0.co;2-9","article-title":"Lactic acidosis: a metabolic complication of hematologic malignancies: case report and review of the literature","volume":"92","author":"Sillos EM","year":"2001","unstructured":"Sillos EM, Shenep JL, Burghen GA, Pui CH, Behm FG, Sandlund JT. Lactic acidosis: a metabolic complication of hematologic malignancies: case report and review of the literature. Cancer. 2001, 92:2237-46. 10.1002\/1097-0142(20011101)92:9&lt;2237::aid-cncr1569&gt;3.0.co;2-9","journal-title":"Cancer"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1126\/science.123.3191.309","article-title":"On the origin of cancer cells","volume":"123","author":"Warburg O","year":"1956","unstructured":"Warburg O. On the origin of cancer cells. Science. 1956, 123:309-14. 10.1126\/science.123.3191.309","journal-title":"Science"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2017.211","article-title":"Oncogene-driven metabolic alterations in cancer","volume":"26","author":"Min HY","year":"2018","unstructured":"Min HY, Lee HY. Oncogene-driven metabolic alterations in cancer. Biomol Ther (Seoul). 2018, 26:45-56. 10.4062\/biomolther.2017.211","journal-title":"Biomol Ther (Seoul)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-016-0913-1","article-title":"Metabolic liver diseases presenting as acute liver failure in children","volume":"53","author":"Alam S","year":"2016","unstructured":"Alam S, Lal BB. Metabolic liver diseases presenting as acute liver failure in children. Indian Pediatr. 2016, 53:695-701. 10.1007\/s13312-016-0913-1","journal-title":"Indian Pediatr"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2010.09.003","article-title":"Oxidative phosphorylation in cancer cells","volume":"1807","author":"Solaini G","year":"2011","unstructured":"Solaini G, Sgarbi G, Baracca A. Oxidative phosphorylation in cancer cells. Biochim Biophys Acta. 2011, 1807:534-42. 10.1016\/j.bbabio.2010.09.003","journal-title":"Biochim Biophys Acta"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.23208","article-title":"Inflammatory responses and inflammation-associated diseases in organs","volume":"9","author":"Chen L","year":"2018","unstructured":"Chen L, Deng H, Cui H, et al.. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget. 2018, 9:7204-18. 10.18632\/oncotarget.23208","journal-title":"Oncotarget"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/cc1824","article-title":"Bench-to-bedside review: cytopathic hypoxia","volume":"6","author":"Fink MP","year":"2002","unstructured":"Fink MP. Bench-to-bedside review: cytopathic hypoxia. Crit Care. 2002, 6:491-9. 10.1186\/cc1824","journal-title":"Crit Care"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2013.07.004","article-title":"Kidney involvement in leukemia and lymphoma","volume":"21","author":"Luciano RL","year":"2014","unstructured":"Luciano RL, Brewster UC. Kidney involvement in leukemia and lymphoma. Adv Chronic Kidney Dis. 2014, 21:27-35. 10.1053\/j.ackd.2013.07.004","journal-title":"Adv Chronic Kidney Dis"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/cc1518","article-title":"Bench-to-bedside review: lactate and the kidney","volume":"6","author":"Bellomo R","year":"2002","unstructured":"Bellomo R. Bench-to-bedside review: lactate and the kidney. Crit Care. 2002, 6:322-6. 10.1186\/cc1518","journal-title":"Crit Care"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.4103\/ijn.IJN_181_16","article-title":"Type B lactic acidosis: a rare initial presentation of childhood acute lymphoblastic leukemia","volume":"29","author":"Narayani S","year":"2019","unstructured":"Narayani S, Balu P, Santhanam R, Scott JX. Type B lactic acidosis: a rare initial presentation of childhood acute lymphoblastic leukemia. Indian J Nephrol. 2019, 29:71-3. 10.4103\/ijn.IJN_181_16","journal-title":"Indian J Nephrol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.26557","article-title":"An oncological emergency: severe type B lactic acidosis from Warburg effect in diffuse large B-cell lymphoma","volume":"14","author":"Sanivarapu R","year":"2022","unstructured":"Sanivarapu R, Upadrista PK, Otero-Colon J, Shah K, Cadet B, Tao Q, Iqbal J. An oncological emergency: severe type B lactic acidosis from Warburg effect in diffuse large B-cell lymphoma. Cureus. 2022, 14:e26557. 10.7759\/cureus.26557","journal-title":"Cureus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/258966-unmasking-the-rarity-a-case-report-on-type-b-lactic-acidosis-in-pediatric-acute-lymphoblastic-leukemia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T05:15:20Z","timestamp":1716873320000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/258966-unmasking-the-rarity-a-case-report-on-type-b-lactic-acidosis-in-pediatric-acute-lymphoblastic-leukemia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,27]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.61201","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5,27]]}}}